#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51649 uniprotkb:P51649 intact:EBI-2684180|uniprotkb:Q546H9|uniprotkb:B2RD26|uniprotkb:G5E949|uniprotkb:Q8N3W6|ensembl:ENSP00000350191 intact:EBI-2684180|uniprotkb:Q546H9|uniprotkb:B2RD26|uniprotkb:G5E949|uniprotkb:Q8N3W6|ensembl:ENSP00000350191 psi-mi:ssdh_human(display_long)|uniprotkb:SSADH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 5 member A1(gene name synonym)|uniprotkb:"NAD(+)-dependent succinic semialdehyde dehydrogenase"(gene name synonym)|uniprotkb:ALDH5A1(gene name)|psi-mi:ALDH5A1(display_short) psi-mi:ssdh_human(display_long)|uniprotkb:SSADH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 5 member A1(gene name synonym)|uniprotkb:"NAD(+)-dependent succinic semialdehyde dehydrogenase"(gene name synonym)|uniprotkb:ALDH5A1(gene name)|psi-mi:ALDH5A1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Kim et al. (2009) mint:MINT-7263394|pubmed:19300440|imex:IM-13803|doi:10.1038/emboj.2009.40 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8598941|mint:MINT-7264027|imex:IM-13803-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001071.1|refseq:NP_733936.1|ensembl:ENSG00000112294(gene)|ensembl:ENST00000357578(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51649|rcsb pdb:2W8N|rcsb pdb:2W8O|rcsb pdb:2W8P|rcsb pdb:2W8Q|rcsb pdb:2W8R|reactome:R-HSA-916853|mint:MINT-7264029(identity) refseq:NP_001071.1|refseq:NP_733936.1|ensembl:ENSG00000112294(gene)|ensembl:ENST00000357578(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51649|rcsb pdb:2W8N|rcsb pdb:2W8O|rcsb pdb:2W8P|rcsb pdb:2W8Q|rcsb pdb:2W8R|reactome:R-HSA-916853|mint:MINT-7264029(identity) - comment:"Stoichiometry: 4.0" comment:"Stoichiometry: 4.0" figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/22 2014/10/16 rogid:gCoItLXLp6W0Cr45kAu+XwADFAs9606 rogid:gCoItLXLp6W0Cr45kAu+XwADFAs9606 intact-crc:5977748075CCBDDD|rigid:6+BtBO8GdePGKdBGoXKEJWRXL1s false - - 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)