#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q04477 uniprotkb:P40014 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598458|mint:MINT-7233853|imex:IM-13802-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233855(identity) refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233857(identity) - crc64:8BE4B8619DD4C8FB crc64:1BED6CCFF330A5D8 figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292 intact-crc:86143BF09590396C|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P40460 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598458|mint:MINT-7233853|imex:IM-13802-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233855(identity) sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233859(identity) - crc64:8BE4B8619DD4C8FB crc64:7DBC492227A80093 figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292 intact-crc:86143BF09590396C|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P54199 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598458|mint:MINT-7233853|imex:IM-13802-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233855(identity) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233858(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 intact-crc:86143BF09590396C|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P33895 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8 psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598458|mint:MINT-7233853|imex:IM-13802-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233855(identity) ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N|mint:MINT-7233860(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292 intact-crc:86143BF09590396C|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P53148 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-23870|uniprotkb:D6VU52|ensemblfungi:YGL093W psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:sp105_yeast(display_long)|uniprotkb:SPC105(gene name)|psi-mi:SPC105(display_short)|uniprotkb:105 kDa spindle pole component protein(gene name synonym)|uniprotkb:YGL093W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598458|mint:MINT-7233853|imex:IM-13802-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233855(identity) refseq:NP_011422.1|sgd:S000003061|dip:DIP-3019N|mint:P53148|ensemblfungi:YGL093W(gene)|ensemblfungi:YGL093W_mRNA(transcript)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005739"(mitochondrion)|go:"GO:0005816"(spindle pole body)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031617"(NMS complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR013253(Kinetochore Spc7)|interpro:IPR033338|rcsb pdb:4BL0|go:"GO:0000776"(kinetochore)|mint:MINT-7233856(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:aLqZ4g/cTEcu988yJCPrbLM34N8559292 intact-crc:86143BF09590396C|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P54199 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598482|mint:MINT-7233874|imex:IM-13802-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233886(identity) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233880(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 intact-crc:0F33DC4FF59F7E09|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - myc tag:?-?(MINT-7233890) - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P53148 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-23870|uniprotkb:D6VU52|ensemblfungi:YGL093W psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:sp105_yeast(display_long)|uniprotkb:SPC105(gene name)|psi-mi:SPC105(display_short)|uniprotkb:105 kDa spindle pole component protein(gene name synonym)|uniprotkb:YGL093W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598482|mint:MINT-7233874|imex:IM-13802-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233886(identity) refseq:NP_011422.1|sgd:S000003061|dip:DIP-3019N|mint:P53148|ensemblfungi:YGL093W(gene)|ensemblfungi:YGL093W_mRNA(transcript)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005739"(mitochondrion)|go:"GO:0005816"(spindle pole body)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031617"(NMS complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR013253(Kinetochore Spc7)|interpro:IPR033338|rcsb pdb:4BL0|go:"GO:0000776"(kinetochore)|mint:MINT-7233884(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:aLqZ4g/cTEcu988yJCPrbLM34N8559292 intact-crc:0F33DC4FF59F7E09|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P40460 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598482|mint:MINT-7233874|imex:IM-13802-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233886(identity) sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233878(identity) - crc64:8BE4B8619DD4C8FB crc64:7DBC492227A80093 figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292 intact-crc:0F33DC4FF59F7E09|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P33895 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-12377|uniprotkb:Q6B1X5|ensemblfungi:YOL069W|uniprotkb:D6W1Z8 psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:nuf2_yeast(display_long)|uniprotkb:YOL069W(locus name)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598482|mint:MINT-7233874|imex:IM-13802-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233886(identity) ensemblfungi:YOL069W(gene)|ensemblfungi:YOL069W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|rcsb pdb:5TCS|rcsb pdb:5TD8|go:"GO:0045132"(meiotic chromosome segregation)|refseq:NP_014572.1|sgd:S000005430|mint:P33895|dip:DIP-1481N|mint:MINT-7233876(identity) - crc64:8BE4B8619DD4C8FB - figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:oof/8nhKWQCx5bp4lvc7f33OO+0559292 intact-crc:0F33DC4FF59F7E09|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04477 uniprotkb:P40014 intact:EBI-27228|uniprotkb:D6VZU0|ensemblfungi:YMR117C intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C psi-mi:spc24_yeast(display_long)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short)|uniprotkb:YM9718.16C(orf name)|uniprotkb:YMR117C(locus name) psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8598482|mint:MINT-7233874|imex:IM-13802-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013835.1|sgd:S000004723|mint:Q04477|dip:DIP-893N|ensemblfungi:YMR117C(gene)|ensemblfungi:YMR117C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233886(identity) refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233882(identity) - crc64:8BE4B8619DD4C8FB crc64:1BED6CCFF330A5D8 figure legend:f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:B12w0JvNs2He1WjK6c241nF3pZc559292 rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292 intact-crc:0F33DC4FF59F7E09|rigid:yCCuiNhnvxnzHlShmXN2C4RGrgU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P54199 uniprotkb:P40460 intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name) psi-mi:"MI:0096"(pull down) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8598518|mint:MINT-7233901|imex:IM-13802-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233907(identity) sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233905(identity) - - crc64:7DBC492227A80093 figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292 intact-crc:77946C5E1B2F3E6B|rigid:upa3SErK9pFNlxDo3/TS7vkIILc false flag tag:?-?(MINT-7233922) his tag:?-?(MINT-7233925)|binding-associated region:1-257(MINT-7233927) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P54199 uniprotkb:P40460 intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name) psi-mi:"MI:0424"(protein kinase assay) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8598548|mint:MINT-7233930|imex:IM-13802-1 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233932(identity) sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|mint:MINT-7233936(identity) - - crc64:7DBC492227A80093 figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292 intact-crc:8EEBEA177C7DB9DF|rigid:upa3SErK9pFNlxDo3/TS7vkIILc false - binding-associated region:1-257(MINT-7233937) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P54199 uniprotkb:P54199 intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C intact:EBI-11224|uniprotkb:D6VRW4|ensemblfungi:YDL028C psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:mps1_yeast(display_long)|uniprotkb:RPK1(gene name synonym)|uniprotkb:D2785(orf name)|uniprotkb:YDL028C(locus name)|uniprotkb:MPS1(gene name)|psi-mi:MPS1(display_short)|uniprotkb:Regulatory cell proliferation kinase 1(gene name synonym)|uniprotkb:Monopolar spindle protein 1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Kemmler et al. (2009) mint:MINT-7233845|pubmed:19300438|imex:IM-13802|doi:10.1038/emboj.2009.62 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8598563|mint:MINT-7233949|imex:IM-13802-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233951(identity) go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensemblfungi:YDL028C(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensemblfungi:YDL028C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016242(Serine/threonine-protein kinase MPS1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|go:"GO:0051225"(spindle assembly)|refseq:NP_010256.2|sgd:S000002186|mint:P54199|dip:DIP-5897N|mint:MINT-7233953(identity) - - - figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/29 2014/10/16 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 rogid:/Q6Ns18JTjPjJZxx8LLt1tiJRdM559292 intact-crc:3660C4FA79A2B9E4|rigid:FJNioFhaDd4+LxlzsBxMYgupCHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)