#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32366	uniprotkb:P32563	intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C	intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C	psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym)	psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Thaker et al. (2009)	mint:MINT-7011761|pubmed:19289121|doi:10.1016/j.febslet.2009.03.013|mint:d-09-00187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8593021|mint:MINT-7012028	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N|mint:MINT-7012030(identity)	sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563|mint:MINT-7012031(identity)	-	crc64:53A19450CAF35632	crc64:77709A914410CD4D	figure legend:F3|kinetics:kd 60 nanomolar|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/03/09	2014/10/16	rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292	rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292	intact-crc:DB01031CE2B62EA3|rigid:09YDVLEiuSJ7h6po9FyS9scqtqY	false	-	binding-associated region:1-388(MINT-7012036)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32366	uniprotkb:P17255	intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym)	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Thaker et al. (2009)	mint:MINT-7011761|pubmed:19289121|doi:10.1016/j.febslet.2009.03.013|mint:d-09-00187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8593036|mint:MINT-7012041	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N|mint:MINT-7012047(identity)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N|mint:MINT-7012043(identity)	-	crc64:53A19450CAF35632	crc64:2A4C65D2F59426FD	figure legend:F5D|comment:homomint|kinetics:kd 200 nanomolar|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/03/09	2014/10/16	rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	intact-crc:0A62A643D6E52F19|rigid:AmtkHqybx/a6utgUCXZGAFXhBFg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17255	uniprotkb:P32366	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym)	psi-mi:"MI:0052"(fluorescence correlation spectroscopy)	Thaker et al. (2009)	mint:MINT-7011761|pubmed:19289121|doi:10.1016/j.febslet.2009.03.013|mint:d-09-00187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8593057|mint:MINT-7012054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N|mint:MINT-7012056(identity)	sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N|mint:MINT-7012058(identity)	-	crc64:2A4C65D2F59426FD	crc64:53A19450CAF35632	figure legend:F5B F5C|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/03/09	2014/10/16	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292	intact-crc:9E31562B6C34B1C2|rigid:AmtkHqybx/a6utgUCXZGAFXhBFg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)