#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q19818	uniprotkb:Q95YF3	intact:EBI-2292125|ensemblmetazoa:F26F4.7.1	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	psi-mi:q19818_caeel(display_long)|uniprotkb:nhl-2(gene name)|psi-mi:nhl-2(display_short)|uniprotkb:F26F4.7(orf name)|uniprotkb:CELE_F26F4.7(orf name)	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:"MI:0018"(two hybrid)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292145|imex:IM-12072-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027370|refseq:NP_498026.1|wormbase:F26F4.7|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001258(NHL repeat)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR017907|reactome:R-CEL-3899300|ensemblmetazoa:F26F4.7.1(transcript)|ensemblmetazoa:WBGene00003598(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043186"(P granule)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045962"(positive regulation of development, heterochronic)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:2000114"(regulation of establishment of cell polarity)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4B, 4C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/03/19	2014/10/16	rogid:UkpH4NhnCWEgM2pMCYFyEd4dpOY6239	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	intact-crc:9F454C9C7CAE7C97|rigid:qApomkW4Q7TPsZcs9FnMiGOfe48	false	-	sufficient binding region:81-430	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q19818	uniprotkb:Q95YF3	intact:EBI-2292125|ensemblmetazoa:F26F4.7.1	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	psi-mi:q19818_caeel(display_long)|uniprotkb:nhl-2(gene name)|psi-mi:nhl-2(display_short)|uniprotkb:F26F4.7(orf name)|uniprotkb:CELE_F26F4.7(orf name)	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292159|imex:IM-12072-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027370|refseq:NP_498026.1|wormbase:F26F4.7|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001258(NHL repeat)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR017907|reactome:R-CEL-3899300|ensemblmetazoa:F26F4.7.1(transcript)|ensemblmetazoa:WBGene00003598(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043186"(P granule)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045962"(positive regulation of development, heterochronic)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:2000114"(regulation of establishment of cell polarity)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:Fig. 4D, 4CE|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2009/03/19	2014/10/16	rogid:UkpH4NhnCWEgM2pMCYFyEd4dpOY6239	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	intact-crc:F58586F6D3D73DE4|rigid:qApomkW4Q7TPsZcs9FnMiGOfe48	false	red fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q95YF3	uniprotkb:O16720	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-895826|ensemblmetazoa:T07D3.7a.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:o16720_caeel(display_long)|uniprotkb:alg-2(gene name)|psi-mi:alg-2(display_short)|uniprotkb:CELE_T07D3.7(orf name)|uniprotkb:T07D3.7(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292178|imex:IM-12072-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	refseq:NP_871992.1|wormbase:T07D3.7a|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|reactome:R-CEL-426486|interpro:IPR036085|interpro:IPR036397|reactome:R-CEL-5578749|reactome:R-CEL-203927|ensemblmetazoa:T07D3.7a.1(transcript)|ensemblmetazoa:WBGene00000106(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016442"(RISC complex)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070922"(small RNA loading onto RISC)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:4vRGlCA5IkZqSyp7DBXn9y+TFuU6239	intact-crc:289328A80DD566E9|rigid:NHveYFkgsSm1OS/xJASbC6y8qbU	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q95YF3	uniprotkb:G5EGR6	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-895878|ensemblmetazoa:F48F7.1a.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:g5egr6_caeel(display_long)|uniprotkb:alg-1(gene name)|psi-mi:alg-1(display_short)|uniprotkb:CELE_F48F7.1(orf name)|uniprotkb:F48F7.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292178|imex:IM-12072-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	uniprotkb:Q20578(uniprot-removed-ac)|refseq:NP_001257238.1|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|wormbase:F48F7.1a|interpro:IPR036085|interpro:IPR036397|ensemblmetazoa:F48F7.1a.1(transcript)|ensemblmetazoa:WBGene00000105(gene)|go:"GO:0000932"(P-body)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016442"(RISC complex)|go:"GO:0035198"(miRNA binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:3GiD5YAB87O34OGTkIBCLSPGnUg6239	intact-crc:289328A80DD566E9|rigid:NHveYFkgsSm1OS/xJASbC6y8qbU	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q95YF3	uniprotkb:Q17740	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-317221|ensemblmetazoa:C06G1.4.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:q17740_caeel(display_long)|uniprotkb:ain-1(gene name)|psi-mi:ain-1(display_short)|uniprotkb:C06G1.4(orf name)|uniprotkb:CELE_C06G1.4(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292211|imex:IM-12072-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	refseq:NP_510687.2|wormbase:C06G1.4|ensemblmetazoa:C06G1.4.1(transcript)|ensemblmetazoa:WBGene00015547(gene)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|mint:Q17740	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C, 6D|comment:RNase treatment of immunoprecipitated material reduces CGH-1 binding to core miRISC components but does not dramatically affect its interaction with NHL-2. Coimmunoprecipitation of ALG-1/2 and AIN-1 with CGH-1 is not affected in the absence of nhl-2.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:0cbGaPitGt4B4rJbCr0Mml+zxvQ6239	intact-crc:CCC9437DBB07E4E4|rigid:mgPmKRP/pXI2YOM5W+SPsfhisvQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q95YF3	uniprotkb:G5EGR6	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-895878|ensemblmetazoa:F48F7.1a.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:g5egr6_caeel(display_long)|uniprotkb:alg-1(gene name)|psi-mi:alg-1(display_short)|uniprotkb:CELE_F48F7.1(orf name)|uniprotkb:F48F7.1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292211|imex:IM-12072-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	uniprotkb:Q20578(uniprot-removed-ac)|refseq:NP_001257238.1|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|wormbase:F48F7.1a|interpro:IPR036085|interpro:IPR036397|ensemblmetazoa:F48F7.1a.1(transcript)|ensemblmetazoa:WBGene00000105(gene)|go:"GO:0000932"(P-body)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016442"(RISC complex)|go:"GO:0035198"(miRNA binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C, 6D|comment:RNase treatment of immunoprecipitated material reduces CGH-1 binding to core miRISC components but does not dramatically affect its interaction with NHL-2. Coimmunoprecipitation of ALG-1/2 and AIN-1 with CGH-1 is not affected in the absence of nhl-2.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:3GiD5YAB87O34OGTkIBCLSPGnUg6239	intact-crc:CCC9437DBB07E4E4|rigid:mgPmKRP/pXI2YOM5W+SPsfhisvQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q95YF3	uniprotkb:O16720	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-895826|ensemblmetazoa:T07D3.7a.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:o16720_caeel(display_long)|uniprotkb:alg-2(gene name)|psi-mi:alg-2(display_short)|uniprotkb:CELE_T07D3.7(orf name)|uniprotkb:T07D3.7(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292211|imex:IM-12072-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	refseq:NP_871992.1|wormbase:T07D3.7a|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|reactome:R-CEL-426486|interpro:IPR036085|interpro:IPR036397|reactome:R-CEL-5578749|reactome:R-CEL-203927|ensemblmetazoa:T07D3.7a.1(transcript)|ensemblmetazoa:WBGene00000106(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016442"(RISC complex)|go:"GO:0016892"(endoribonuclease activity, producing 3'-phosphomonoesters)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070922"(small RNA loading onto RISC)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C, 6D|comment:RNase treatment of immunoprecipitated material reduces CGH-1 binding to core miRISC components but does not dramatically affect its interaction with NHL-2. Coimmunoprecipitation of ALG-1/2 and AIN-1 with CGH-1 is not affected in the absence of nhl-2.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:4vRGlCA5IkZqSyp7DBXn9y+TFuU6239	intact-crc:CCC9437DBB07E4E4|rigid:mgPmKRP/pXI2YOM5W+SPsfhisvQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q95YF3	uniprotkb:Q19818	intact:EBI-314525|ensemblmetazoa:C07H6.5.1	intact:EBI-2292125|ensemblmetazoa:F26F4.7.1	psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short)	psi-mi:q19818_caeel(display_long)|uniprotkb:nhl-2(gene name)|psi-mi:nhl-2(display_short)|uniprotkb:F26F4.7(orf name)|uniprotkb:CELE_F26F4.7(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hammell et al. (2009)	imex:IM-12072|pubmed:19269369	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2292211|imex:IM-12072-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N	interpro:IPR027370|refseq:NP_498026.1|wormbase:F26F4.7|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001258(NHL repeat)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR017907|reactome:R-CEL-3899300|ensemblmetazoa:F26F4.7.1(transcript)|ensemblmetazoa:WBGene00003598(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043186"(P granule)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045962"(positive regulation of development, heterochronic)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:2000114"(regulation of establishment of cell polarity)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C, 6D|comment:RNase treatment of immunoprecipitated material reduces CGH-1 binding to core miRISC components but does not dramatically affect its interaction with NHL-2. Coimmunoprecipitation of ALG-1/2 and AIN-1 with CGH-1 is not affected in the absence of nhl-2.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm)	-	2009/03/19	2014/10/16	rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239	rogid:UkpH4NhnCWEgM2pMCYFyEd4dpOY6239	intact-crc:CCC9437DBB07E4E4|rigid:mgPmKRP/pXI2YOM5W+SPsfhisvQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)