#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5JRA6 uniprotkb:Q02388 intact:EBI-2291868|uniprotkb:A8K2S0|uniprotkb:A8MT05|uniprotkb:A8MT13|uniprotkb:B7Z430|uniprotkb:Q3S4X3|uniprotkb:Q5JRB0|uniprotkb:Q14083|uniprotkb:Q5JRA5|uniprotkb:Q5JRB1|uniprotkb:Q5JRB2|uniprotkb:Q6UVY8|uniprotkb:Q86Y60|uniprotkb:Q8N8M5|uniprotkb:Q92580|intact:EBI-2803073|ensembl:ENSP00000340900 intact:EBI-724237|ensembl:ENSP00000332371|ensembl:ENSP00000506558|uniprotkb:Q14054|uniprotkb:Q16507 psi-mi:tgo1_human(display_long)|uniprotkb:TANGO(gene name synonym)|uniprotkb:MIA3(gene name)|psi-mi:MIA3(display_short)|uniprotkb:KIAA0268(gene name synonym)|uniprotkb:C219-reactive peptide(gene name synonym)|uniprotkb:D320(gene name synonym)|uniprotkb:UNQ6077/PRO20088(orf name)|uniprotkb:Melanoma inhibitory activity protein 3(gene name synonym) psi-mi:co7a1_human(display_long)|uniprotkb:Long-chain collagen(gene name synonym)|uniprotkb:COL7A1(gene name)|psi-mi:COL7A1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Saito et al. (2009) imex:IM-12070|pubmed:19269366|mint:MINT-7215289 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291917|imex:IM-12070-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940953.2|refseq:NP_001287796.1|ensembl:ENSG00000154305(gene)|ensembl:ENST00000344922(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|refseq:NP_001310992.1|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:2000402"(negative regulation of lymphocyte migration)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275 refseq:NP_000085.1|ensembl:ENSG00000114270(gene)|ensembl:ENST00000328333(transcript)|ensembl:ENST00000681320(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005590"(collagen type VII trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036116|interpro:IPR036465|interpro:IPR036880|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-204005|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-3000157|reactome:R-HSA-5694530|reactome:R-HSA-8948216|refseq:XP_011531639.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/03/18 2014/10/16 rogid:DGy7mQTlQIbcaklbpG7jmdj9G/I9606 rogid:ToEHGFeu7cs5I0xYYeKHCvb7Xy09606 intact-crc:7AE0CBC2C32C764C|rigid:b0FD3NU8HdRXaJYG6kdPwyyrffw false - identified peptide:852-878,1015-1036,90-105,728-754,59-78,1958-1976 - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q02388 uniprotkb:Q5JRA6 intact:EBI-724237|ensembl:ENSP00000332371|ensembl:ENSP00000506558|uniprotkb:Q14054|uniprotkb:Q16507 intact:EBI-2291868|uniprotkb:A8K2S0|uniprotkb:A8MT05|uniprotkb:A8MT13|uniprotkb:B7Z430|uniprotkb:Q3S4X3|uniprotkb:Q5JRB0|uniprotkb:Q14083|uniprotkb:Q5JRA5|uniprotkb:Q5JRB1|uniprotkb:Q5JRB2|uniprotkb:Q6UVY8|uniprotkb:Q86Y60|uniprotkb:Q8N8M5|uniprotkb:Q92580|intact:EBI-2803073|ensembl:ENSP00000340900 psi-mi:co7a1_human(display_long)|uniprotkb:Long-chain collagen(gene name synonym)|uniprotkb:COL7A1(gene name)|psi-mi:COL7A1(display_short) psi-mi:tgo1_human(display_long)|uniprotkb:TANGO(gene name synonym)|uniprotkb:MIA3(gene name)|psi-mi:MIA3(display_short)|uniprotkb:KIAA0268(gene name synonym)|uniprotkb:C219-reactive peptide(gene name synonym)|uniprotkb:D320(gene name synonym)|uniprotkb:UNQ6077/PRO20088(orf name)|uniprotkb:Melanoma inhibitory activity protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Saito et al. (2009) imex:IM-12070|pubmed:19269366|mint:MINT-7215289 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2291935|imex:IM-12070-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000085.1|ensembl:ENSG00000114270(gene)|ensembl:ENST00000328333(transcript)|ensembl:ENST00000681320(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005590"(collagen type VII trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036116|interpro:IPR036465|interpro:IPR036880|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-204005|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-3000157|reactome:R-HSA-5694530|reactome:R-HSA-8948216|refseq:XP_011531639.1 refseq:NP_940953.2|refseq:NP_001287796.1|ensembl:ENSG00000154305(gene)|ensembl:ENST00000344922(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|refseq:NP_001310992.1|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:2000402"(negative regulation of lymphocyte migration)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 4B|comment:COL7A1 transfected into cell line deficient in this protein|caution:Coordinates of Q5JRA6 SH3 construct not given in paper so have been inferred from the UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/03/18 2014/10/16 rogid:ToEHGFeu7cs5I0xYYeKHCvb7Xy09606 rogid:DGy7mQTlQIbcaklbpG7jmdj9G/I9606 intact-crc:DFACE727270D0304|rigid:b0FD3NU8HdRXaJYG6kdPwyyrffw false - flag tag:c-c|necessary binding region:45..45-107..107(IPR001452) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)