#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q0P564	uniprotkb:O54822	intact:EBI-8552790|intact:MINT-6823052|ensembl:ENSBTAP00000026031	intact:EBI-8552809|intact:MINT-6823037	psi-mi:crbn_bovin(display_long)|uniprotkb:CRBN(gene name)|psi-mi:CRBN(display_short)	psi-mi:o54822_rat(display_long)|uniprotkb:ClC-2(gene name)|psi-mi:ClC-2(display_short)	psi-mi:"MI:0018"(two hybrid)	Hohberger et al. (2009)	mint:MINT-6822955|pubmed:19166841|imex:IM-11636|doi:10.1016/j.febslet.2009.01.018|mint:d-08-02275	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8552785|mint:MINT-6823070|imex:IM-11636-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001068995.1|ensembl:ENSBTAG00000019536(gene)|ensembl:ENSBTAT00000026031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1902607"(negative regulation of large conductance calcium-activated potassium channel activity)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR004910(Yippee-like protein)|interpro:IPR015947(PUA-like)|interpro:IPR034750|mint:Q0P564|mint:MINT-6823073(identity)	interpro:IPR002244(Chloride channel CLC-2)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|mint:O54822|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|mint:MINT-6823072(identity)	-	comment:mint	comment:mint	figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/01/08	2014/10/16	rogid:JvZpxvdOh1lwWs3QWhxzFyxJ7BA9913	rogid:lMrhcpyVWroTvKDzWQr478S5eUc10116	intact-crc:B248EF834542D13A|rigid:6KfK/0SE6VIsEvf5IDokUoJO6xc	false	tag:?-?(MINT-6823101)	tag:?-?(MINT-6823087)|binding-associated region:559-887(MINT-6823090)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O54822	uniprotkb:A4FUY8	intact:EBI-8552809|intact:MINT-6823037	intact:EBI-8552844|intact:MINT-6823122|uniprotkb:F1MWA0|ensembl:ENSBTAP00000020011	psi-mi:o54822_rat(display_long)|uniprotkb:ClC-2(gene name)|psi-mi:ClC-2(display_short)	psi-mi:a4fuy8_bovin(display_long)|uniprotkb:IK(gene name)|psi-mi:IK(display_short)	psi-mi:"MI:0018"(two hybrid)	Hohberger et al. (2009)	mint:MINT-6822955|pubmed:19166841|imex:IM-11636|doi:10.1016/j.febslet.2009.01.018|mint:d-08-02275	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8552839|mint:MINT-6823105|imex:IM-11636-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002244(Chloride channel CLC-2)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|mint:O54822|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|mint:MINT-6823107(identity)	refseq:NP_001096819.1|ensembl:ENSBTAG00000015034(gene)|ensembl:ENSBTAT00000020011(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016607"(nuclear speck)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012492(RED-like, C-terminal)|interpro:IPR012916(RED-like, N-terminal)|interpro:IPR039896|mint:A4FUY8|go:"GO:0042802"(identical protein binding)|mint:MINT-6823113(identity)	-	comment:mint	comment:mint	figure legend:F1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/01/08	2014/10/16	rogid:lMrhcpyVWroTvKDzWQr478S5eUc10116	rogid:mguGRrFDmbilb6eeEkCxKJjgXoY9913	intact-crc:B5501E457AA2AD1A|rigid:O/RCbk+k1roOwT3bXlk+n4vEfG8	false	tag:?-?(MINT-6823110)|binding-associated region:559-887(MINT-6823108)	tag:?-?(MINT-6823114)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q56AP7	uniprotkb:O54822	intact:EBI-8552884|uniprotkb:A1L110|uniprotkb:Q499S7|intact:UNK-5421359|ensembl:ENSRNOP00000008873	intact:EBI-8552809|intact:MINT-6823037	psi-mi:crbn_rat(display_long)|uniprotkb:Crbn(gene name)|psi-mi:Crbn(display_short)	psi-mi:o54822_rat(display_long)|uniprotkb:ClC-2(gene name)|psi-mi:ClC-2(display_short)	psi-mi:"MI:0096"(pull down)	Hohberger et al. (2009)	mint:MINT-6822955|pubmed:19166841|imex:IM-11636|doi:10.1016/j.febslet.2009.01.018|mint:d-08-02275	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8552910|mint:MINT-6823160|imex:IM-11636-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001015003.1|rgd:1310533|ensembl:ENSRNOG00000006534(gene)|ensembl:ENSRNOT00000008873(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902607"(negative regulation of large conductance calcium-activated potassium channel activity)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR004910(Yippee-like protein)|interpro:IPR015947(PUA-like)|interpro:IPR034750|mint:Q56AP7|mint:MINT-6823168(identity)	interpro:IPR002244(Chloride channel CLC-2)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|mint:O54822|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|mint:MINT-6823162(identity)	-	function:"May be involved in memory and learning (By similarity). Modulates cell surface expression of KCNT1"|comment:mint	comment:mint	figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/08	2014/10/16	rogid:qoGMz5q/SLWOK3HXRPFuGS0Bqw810116	rogid:lMrhcpyVWroTvKDzWQr478S5eUc10116	intact-crc:9CB5F85CEDB50BA3|rigid:WQQNzngye21+LzrmUrgJYsyZx8o	false	t7 tag:?-?(MINT-6823169)	glutathione s tranferase tag:?-?(MINT-6823165)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O54822	uniprotkb:Q56AP7	intact:EBI-8552809|intact:MINT-6823037	intact:EBI-8552884|uniprotkb:A1L110|uniprotkb:Q499S7|intact:UNK-5421359|ensembl:ENSRNOP00000008873	psi-mi:o54822_rat(display_long)|uniprotkb:ClC-2(gene name)|psi-mi:ClC-2(display_short)	psi-mi:crbn_rat(display_long)|uniprotkb:Crbn(gene name)|psi-mi:Crbn(display_short)	psi-mi:"MI:0096"(pull down)	Hohberger et al. (2009)	mint:MINT-6822955|pubmed:19166841|imex:IM-11636|doi:10.1016/j.febslet.2009.01.018|mint:d-08-02275	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8552927|mint:MINT-6823197|imex:IM-11636-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002244(Chloride channel CLC-2)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR014743(Chloride channel, core)|mint:O54822|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|mint:MINT-6823199(identity)	refseq:NP_001015003.1|rgd:1310533|ensembl:ENSRNOG00000006534(gene)|ensembl:ENSRNOT00000008873(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1902607"(negative regulation of large conductance calcium-activated potassium channel activity)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR004910(Yippee-like protein)|interpro:IPR015947(PUA-like)|interpro:IPR034750|mint:Q56AP7|mint:MINT-6823203(identity)	-	comment:mint	function:"May be involved in memory and learning (By similarity). Modulates cell surface expression of KCNT1"|comment:mint	figure legend:F2A F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/08	2014/10/16	rogid:lMrhcpyVWroTvKDzWQr478S5eUc10116	rogid:qoGMz5q/SLWOK3HXRPFuGS0Bqw810116	intact-crc:2A6F53217767D162|rigid:WQQNzngye21+LzrmUrgJYsyZx8o	false	glutathione s tranferase tag:?-?(MINT-6823200)|binding-associated region:751-887(MINT-6823209)	binding-associated region:70-331(MINT-6823212)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)