#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0401"(biochemical) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8551401|mint:MINT-7040883|imex:IM-13851-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040885(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040886(identity) go:"GO:0005634"(nucleus) - - comment:mint|figure legend:f1 st1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2014/10/16 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:3648441EAC3A289E|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q0E8J0 uniprotkb:O97159 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8551422|mint:MINT-7040900|imex:IM-13851-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040903(identity) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040905(identity) go:"GO:0005634"(nucleus) - - figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/12 2014/10/16 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:599043435FB27339|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q0E8J0 uniprotkb:O97159 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8551443|mint:MINT-7040912|imex:IM-13851-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040917(identity) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040915(identity) - - - figure legend:f2c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/05/12 2014/10/16 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:858D15E6F47AF13F|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false binding-associated region:1-679(MINT-7040941)|flag tag:?-?(MINT-7040937) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8551469|mint:MINT-7040972|imex:IM-13851-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040976(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040974(identity) go:"GO:0005634"(nucleus) - - figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2009/05/12 2014/10/16 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:84573FCA678CADB3|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8551490|mint:MINT-7040946|imex:IM-13851-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040954(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040948(identity) - - - comment:mint|comment:The same interaction occurs in ovaries cells.|figure legend:f3d f5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2009/05/12 2014/10/16 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:073A618CB562092D|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8551502|mint:MINT-7040961|imex:IM-13851-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040963(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7040965(identity) - - - figure legend:f3d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2009/05/12 2014/10/16 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:2BA40EC0A3CCBDF1|rigid:Xu5ixhFvL0ua7SUc5sTxtkvj6M4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551522|mint:MINT-7041017|imex:IM-13851-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7041026(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7041024(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:50AF78902422B3B5|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q94517 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551522|mint:MINT-7041017|imex:IM-13851-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7041026(identity) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N|mint:MINT-7041022(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:50AF78902422B3B5|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q9VCK0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-84624|ensemblmetazoa:FBpp0088565|intact:EBI-3403399|uniprotkb:Q9NHP3 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:ei3d1_drome(display_long)|uniprotkb:eIF3d1(gene name)|psi-mi:eIF3d1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7-1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit p66(gene name synonym)|uniprotkb:eIF-3p66(gene name synonym)|uniprotkb:CG10161(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551522|mint:MINT-7041017|imex:IM-13851-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7041026(identity) go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:Q9VCK0|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|ensemblmetazoa:FBgn0040227(gene)|ensemblmetazoa:FBtr0089622(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_524463.2|flybase:FBgn0040227|mint:MINT-7041020(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:4SM2qfgDgJnZJsG2EGV7qKfLWK07227 intact-crc:50AF78902422B3B5|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCK0 uniprotkb:Q94517 intact:EBI-84624|ensemblmetazoa:FBpp0088565|intact:EBI-3403399|uniprotkb:Q9NHP3 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:ei3d1_drome(display_long)|uniprotkb:eIF3d1(gene name)|psi-mi:eIF3d1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7-1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit p66(gene name synonym)|uniprotkb:eIF-3p66(gene name synonym)|uniprotkb:CG10161(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551555|mint:MINT-7041049|imex:IM-13851-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:Q9VCK0|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|ensemblmetazoa:FBgn0040227(gene)|ensemblmetazoa:FBtr0089622(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_524463.2|flybase:FBgn0040227|mint:MINT-7041051(identity) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N|mint:MINT-7041053(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:4SM2qfgDgJnZJsG2EGV7qKfLWK07227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:5B5A6759051341FF|rigid:Yc8nEBF8Ml6RHzvrH8saUdcN2Lc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VCK0 uniprotkb:O97159 intact:EBI-84624|ensemblmetazoa:FBpp0088565|intact:EBI-3403399|uniprotkb:Q9NHP3 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:ei3d1_drome(display_long)|uniprotkb:eIF3d1(gene name)|psi-mi:eIF3d1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7-1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit p66(gene name synonym)|uniprotkb:eIF-3p66(gene name synonym)|uniprotkb:CG10161(orf name) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551555|mint:MINT-7041049|imex:IM-13851-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:Q9VCK0|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|ensemblmetazoa:FBgn0040227(gene)|ensemblmetazoa:FBtr0089622(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_524463.2|flybase:FBgn0040227|mint:MINT-7041051(identity) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7041055(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:4SM2qfgDgJnZJsG2EGV7qKfLWK07227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:5B5A6759051341FF|rigid:Yc8nEBF8Ml6RHzvrH8saUdcN2Lc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q94517 uniprotkb:O97159 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551540|mint:MINT-7041035|imex:IM-13851-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N|mint:MINT-7041041(identity) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7041037(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 intact-crc:9FDAC35F808541FA|rigid:Yc8nEBF8Ml6RHzvrH8saUdcN2Lc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q94517 uniprotkb:Q9VCK0 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 intact:EBI-84624|ensemblmetazoa:FBpp0088565|intact:EBI-3403399|uniprotkb:Q9NHP3 psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:ei3d1_drome(display_long)|uniprotkb:eIF3d1(gene name)|psi-mi:eIF3d1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7-1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit p66(gene name synonym)|uniprotkb:eIF-3p66(gene name synonym)|uniprotkb:CG10161(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8551540|mint:MINT-7041035|imex:IM-13851-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N|mint:MINT-7041041(identity) go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:Q9VCK0|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|ensemblmetazoa:FBgn0040227(gene)|ensemblmetazoa:FBtr0089622(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_524463.2|flybase:FBgn0040227|mint:MINT-7041043(identity) - - - comment:homomint|comment:mint|figure legend:F5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 rogid:4SM2qfgDgJnZJsG2EGV7qKfLWK07227 intact-crc:9FDAC35F808541FA|rigid:Yc8nEBF8Ml6RHzvrH8saUdcN2Lc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q9VCK0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-84624|ensemblmetazoa:FBpp0088565|intact:EBI-3403399|uniprotkb:Q9NHP3 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:ei3d1_drome(display_long)|uniprotkb:eIF3d1(gene name)|psi-mi:eIF3d1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7-1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit p66(gene name synonym)|uniprotkb:eIF-3p66(gene name synonym)|uniprotkb:CG10161(orf name) psi-mi:"MI:0027"(cosedimentation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8551579|mint:MINT-7040997|imex:IM-13851-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040999(identity) go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:Q9VCK0|reactome:R-DME-156827|reactome:R-DME-72649|reactome:R-DME-72689|reactome:R-DME-72695|reactome:R-DME-72702|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|ensemblmetazoa:FBgn0040227(gene)|ensemblmetazoa:FBtr0089622(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_524463.2|flybase:FBgn0040227|mint:MINT-7041010(identity) go:"GO:0005634"(nucleus) - - figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:4SM2qfgDgJnZJsG2EGV7qKfLWK07227 intact-crc:193C1676A08CB3C1|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q94517 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0027"(cosedimentation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8551579|mint:MINT-7040997|imex:IM-13851-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040999(identity) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N|mint:MINT-7041007(identity) go:"GO:0005634"(nucleus) - - figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:193C1676A08CB3C1|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O97159 uniprotkb:Q0E8J0 intact:EBI-112333|uniprotkb:Q8MZ43|uniprotkb:Q9VW50|ensemblmetazoa:FBpp0074688|ensemblmetazoa:FBpp0291256 intact:EBI-91014|intact:EBI-1629846|ensemblmetazoa:FBpp0072808|ensemblmetazoa:FBpp0072809|ensemblmetazoa:FBpp0072810|ensemblmetazoa:FBpp0072811|ensemblmetazoa:FBpp0072812|ensemblmetazoa:FBpp0072813|ensemblmetazoa:FBpp0288779 psi-mi:chdm_drome(display_long)|uniprotkb:Mi-2(gene name)|psi-mi:Mi-2(display_short)|uniprotkb:CG8103(orf name)|uniprotkb:ATP-dependent helicase Mi-2(gene name synonym) psi-mi:q0e8j0_drome(display_long)|uniprotkb:MEP-1(gene name)|psi-mi:MEP-1(display_short)|uniprotkb:Dmel\CG1244(gene name synonym)|uniprotkb:MEP1(gene name synonym)|uniprotkb:Q0E8J0_DROME(gene name synonym)|uniprotkb:"anon-EST:Liang-1.37"(gene name synonym)|uniprotkb:anon-WO0118547.584(gene name synonym)|uniprotkb:clone 1.37(gene name synonym)|uniprotkb:dMEP-1(gene name synonym)|uniprotkb:Dmel_CG1244(orf name)|uniprotkb:CG1244(orf name) psi-mi:"MI:0027"(cosedimentation) Kunert et al. (2009) mint:MINT-7040874|pubmed:19165147|imex:IM-13851|doi:10.1038/emboj.2009.3 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8551579|mint:MINT-7040997|imex:IM-13851-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163476.1|refseq:NP_649154.2|flybase:FBgn0262519|dip:DIP-22862N|ensemblmetazoa:FBgn0262519(gene)|ensemblmetazoa:FBtr0074919(transcript)|ensemblmetazoa:FBtr0302046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035327"|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0051312"(chromosome decondensation)|go:"GO:0070615"|go:"GO:0071923"(negative regulation of cohesin loading)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:O97159|reactome:R-DME-3214815|reactome:R-DME-6804758|reactome:R-DME-8943724|mint:MINT-7040999(identity) refseq:NP_001137875.1|refseq:NP_647733.1|refseq:NP_728761.1|refseq:NP_728762.1|refseq:NP_728763.1|refseq:NP_728764.1|refseq:NP_728765.1|flybase:FBgn0035357|ensemblmetazoa:FBgn0035357(gene)|ensemblmetazoa:FBtr0072931(transcript)|ensemblmetazoa:FBtr0072932(transcript)|ensemblmetazoa:FBtr0072933(transcript)|ensemblmetazoa:FBtr0072934(transcript)|ensemblmetazoa:FBtr0072935(transcript)|ensemblmetazoa:FBtr0072936(transcript)|ensemblmetazoa:FBtr0290340(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016581"(NuRD complex)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q0E8J0|mint:MINT-7041001(identity) go:"GO:0005634"(nucleus) - - figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-kc)|taxid:7227(Drosophila melanogaster embryo KC cells) - 2009/05/12 2016/03/30 rogid:AmswZgROGpylfvMV7ZAlNKFF6ZA7227 rogid:rGwbvpMEfM24nz0uz5swcptP1f87227 intact-crc:193C1676A08CB3C1|rigid:X4WmMx/4izqj2B38kIkNtXtbEBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)