#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20936 uniprotkb:Q96QB1 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546086|mint:MINT-7232539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232541(identity) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232542(identity) - - - figure legend:f1a|comment:homomint|comment:mint|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/07/24 2014/10/16 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 intact-crc:36B801ABCA7C98E6|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false binding-associated region:91-511(IPR000980) binding-associated region:590-880(MINT-7232545) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QB1 uniprotkb:P20936 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546117|mint:MINT-7232590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232592(identity) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232597(identity) - - - figure legend:f2b|comment:homomint|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/24 2014/10/16 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 intact-crc:3A5D20029AE6EAA7|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false - glutathione s tranferase tag:?-?(MINT-7232606)|binding-associated region:277-346(MINT-7232598) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20936 uniprotkb:Q96QB1 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546136|mint:MINT-7232612 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232614(identity) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232621(identity) - - - figure legend:f2d|comment:homomint|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/07/24 2014/10/16 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 intact-crc:5B427596459D48EC|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false glutathione s tranferase tag:?-?(MINT-7232615)|binding-associated region:277-346(MINT-7232617) binding-associated region:641-847(MINT-7232627)|v5 tag:?-?(MINT-7232625) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:Q96QB1 uniprotkb:P20936 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546172|mint:MINT-7232556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232558(identity) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232563(identity) - - - figure legend:f1b|comment:homomint|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/07/24 2014/10/16 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 intact-crc:A6126DFA297E6AB0|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q96QB1 uniprotkb:P20936 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546184|mint:MINT-7232576 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232580(identity) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232578(identity) - - - figure legend:f1b|comment:homomint|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/07/24 2014/10/16 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 intact-crc:E76E233B86E44A02|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20936 uniprotkb:Q96QB1 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2009) mint:MINT-7215316|pubmed:19151751|doi:10.1038/onc.2008.498 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8546206|mint:MINT-7232631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7232640(identity) refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N|mint:MINT-7232633(identity) - - - comment:homomint|comment:mint|figure legend:f2c|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/07/24 2014/10/16 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 intact-crc:BCA4A359B19E6496|rigid:XjMQo02tk5+To7Nh8cUndP+Dcyg false - binding-associated region:798-847(MINT-7232634)|v5 tag:?-?(MINT-7232637) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0396"(predetermined participant)