#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P60293	uniprotkb:P22524	intact:EBI-554679|uniprotkb:P36567|ensemblbacteria:AAC74008|ensemblbacteria:BAA35668	intact:EBI-554672|ensemblbacteria:AAC74009|ensemblbacteria:BAA35669	psi-mi:mukf_ecoli(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:kicB(gene name synonym)|uniprotkb:b0922(locus name)|uniprotkb:JW0905(locus name)|uniprotkb:Protein KicB(gene name synonym)	psi-mi:muke_ecoli(display_long)|uniprotkb:ycbA(gene name synonym)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:kicA(gene name synonym)|uniprotkb:b0923(locus name)|uniprotkb:JW0906(locus name)|uniprotkb:Protein KicA(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213576|wwpdb:3EUH|imex:IM-12157-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415442.1|refseq:WP_001288850.1|dip:DIP-39981N|mint:P60293|ensemblbacteria:AAC74008(transcript)|ensemblbacteria:b0922(gene)|ensemblbacteria:BAA35668(gene)|ensemblbacteria:BAA35668(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|interpro:IPR038198|rcsb pdb:1T98|rcsb pdb:3EUH|rcsb pdb:3RPU	refseq:NP_415443.2|refseq:WP_001295347.1|dip:DIP-10274N|mint:P22524|ensemblbacteria:AAC74009(transcript)|ensemblbacteria:b0923(gene)|ensemblbacteria:BAA35669(gene)|ensemblbacteria:BAA35669(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)|interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|interpro:IPR042037|interpro:IPR042038|rcsb pdb:3EUH|rcsb pdb:3RPU	-	-	-	comment:"Through the dimerization of MukF, two copies of the heterotrimeric unit associated with each other to form a large (MukF-(MukE)2)2 hexameric complex"|figure legend:Fig. 1, Supp. Fig. 1|3d-resolution:2.9A|3d-r-factors:22.47% working, 27.05% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	rogid:4jdW6g1N/h18JnHrGERNc1TNd1s83333	rogid:9Wb+/zS/xWsgxo8Rr/GZ3M3EYTk83333	intact-crc:759716F5B89C4799|rigid:WZzPBpPJ40bv/GrVyjwRMq62vl8	false	-	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:27575"	uniprotkb:Q7VL96	intact:EBI-1209042	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:adenosine 5'-[gamma-thio]triphosphate(display_short)|psi-mi:"CHEBI:27575"(display_long)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213614|wwpdb:3EUK|imex:IM-12157-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 2A, Supp. Table 1|3d-resolution:4A|3d-r-factors:26.7% working, 32.2% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:B3A8B7B27C6F6827	false	-	experimental feature:272-1263|mutation:1435-1435|sufficient binding region:34-1496	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:27575"	uniprotkb:Q7VL95	intact:EBI-1209042	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:adenosine 5'-[gamma-thio]triphosphate(display_short)|psi-mi:"CHEBI:27575"(display_long)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213614|wwpdb:3EUK|imex:IM-12157-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 2A, Supp. Table 1|3d-resolution:4A|3d-r-factors:26.7% working, 32.2% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:B3A8B7B27C6F6827	false	-	-	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:27575"	uniprotkb:Q7VL94	intact:EBI-1209042	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:adenosine 5'-[gamma-thio]triphosphate(display_short)|psi-mi:"CHEBI:27575"(display_long)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213614|wwpdb:3EUK|imex:IM-12157-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 2A, Supp. Table 1|3d-resolution:4A|3d-r-factors:26.7% working, 32.2% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:B3A8B7B27C6F6827	false	-	sufficient binding region:293-443	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:27575"	uniprotkb:Q7VL96	intact:EBI-1209042	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:adenosine 5'-[gamma-thio]triphosphate(display_short)|psi-mi:"CHEBI:27575"(display_long)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213645|wwpdb:3EUJ|imex:IM-12157-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 2A, Supp. Table 1|3d-resolution:3.1A|3d-r-factors:25.9% working, 29.0% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:902EACA57EF51A25	false	-	sufficient binding region:34-1496|mutation:1435-1435	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:27575"	uniprotkb:Q7VL94	intact:EBI-1209042	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:adenosine 5'-[gamma-thio]triphosphate(display_short)|psi-mi:"CHEBI:27575"(display_long)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213645|wwpdb:3EUJ|imex:IM-12157-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 2A, Supp. Table 1|3d-resolution:3.1A|3d-r-factors:25.9% working, 29.0% free|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:902EACA57EF51A25	false	-	sufficient binding region:293-443	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1772244	uniprotkb:Q7VL95	-	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:pbr322-ecoli-dna(display_short)|psi-mi:EBI-1772244(display_long)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213666|imex:IM-12157-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank_nucl_gi:208958(primary-reference)	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	go:"GO:0003690"(double-stranded DNA binding)	-	-	figure legend:Fig. 2D|comment:pBR322 was radio-labeled|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:774AB6AF2F74E58A	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-1772244	uniprotkb:Q7VL96	-	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:pbr322-ecoli-dna(display_short)|psi-mi:EBI-1772244(display_long)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213666|imex:IM-12157-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank_nucl_gi:208958(primary-reference)	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	go:"GO:0003690"(double-stranded DNA binding)	-	-	figure legend:Fig. 2D|comment:pBR322 was radio-labeled|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:774AB6AF2F74E58A	false	-	sufficient binding region:34-1496|mutation:1435-1435|mutation disrupting interaction:216-216,218-218|mutation disrupting interaction:146-146|mutation decreasing interaction:104-104,106-106|mutation decreasing interaction:1274-1274,1278-1278|mutation decreasing interaction:1423-1423,1418-1418|mutation decreasing interaction:127-127|experimental feature:272-1263	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-1772244	uniprotkb:Q7VL94	-	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:pbr322-ecoli-dna(display_short)|psi-mi:EBI-1772244(display_long)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213666|imex:IM-12157-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank_nucl_gi:208958(primary-reference)	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	go:"GO:0003690"(double-stranded DNA binding)	-	-	figure legend:Fig. 2D|comment:pBR322 was radio-labeled|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:774AB6AF2F74E58A	false	-	sufficient binding region:293-443	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q7VL96	uniprotkb:Q7VL96	intact:EBI-2213597|ensemblbacteria:AAP96363	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213710|imex:IM-12157-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3C, 3D|comment:Appears to bind ATP or a non-hydrolysable AMPPNP analogue.|stimulant:Presence of the mukE/F protein complex|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:5DE3094B4E2CEBD1|rigid:mlqyBbH6G3Oa7SMcodO91wpy15E	false	sufficient binding region:33-1496|mutation:272-1262	sufficient binding region:33-1496|mutation:272-1262	2	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q7VL94	uniprotkb:Q7VL95	intact:EBI-2213621|ensemblbacteria:AAP96365	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213718|imex:IM-12157-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	psi-mi:"MI:0469"(intact)	-	-	figure legend:FigS. 3C, 4A, 4B|comment:Residues 337-354 of MukF appear to be required for detachment of MukE-MukF from dimerized MukB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:BC1666148A983E07|rigid:PVJrTEJgleFnKTE0pB5aBWP5kXo	false	sufficient binding region:293-443	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:47785"	uniprotkb:Q7VL96	intact:EBI-1554642	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:amp-pnp(display_short)|psi-mi:"CHEBI:47785"(display_long)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213797|imex:IM-12157-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 4A|comment:"mukF containing its C-terminal WHD only (residues 358-440) does not allow dissociation of the complex on ATP binding. Addition of a synthetic peptide consisting of the missing linker region, causes the complex to dissociate."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:2CD8832A89719D56	false	-	mutation:272-1262|sufficient binding region:33-1496	-	2	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:47785"	uniprotkb:Q7VL95	intact:EBI-1554642	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:amp-pnp(display_short)|psi-mi:"CHEBI:47785"(display_long)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213797|imex:IM-12157-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 4A|comment:"mukF containing its C-terminal WHD only (residues 358-440) does not allow dissociation of the complex on ATP binding. Addition of a synthetic peptide consisting of the missing linker region, causes the complex to dissociate."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:2CD8832A89719D56	false	-	-	-	1	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:47785"	uniprotkb:Q7VL94	intact:EBI-1554642	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:amp-pnp(display_short)|psi-mi:"CHEBI:47785"(display_long)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213797|imex:IM-12157-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 4A|comment:"mukF containing its C-terminal WHD only (residues 358-440) does not allow dissociation of the complex on ATP binding. Addition of a synthetic peptide consisting of the missing linker region, causes the complex to dissociate."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:2CD8832A89719D56	false	-	sufficient binding region:358-440	-	1	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:15422"	uniprotkb:Q7VL96	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213775|imex:IM-12157-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 6A, Supp. Fig. 6|comment:"mukB g;u1435gln mutant is catalytically inactive. Once reacted with ATP, as a result of the separation of MukF C-WHD from MukBEQ, this reaction generated five new complexes  with stoichiomentry 1:4, 1:3, 1:2, 1:1 and 1:0 between MukEF and MukB"|comment:ATP contains a radio-labelled tracer|comment:The wild-type MukB-MukEF-MukB complex was reacted with 10 mM ATP or AMPPNP. In the presence of AMPPNP, this complex underwent the same conversion reaction described in this entry. In contrast the ATP-bound, engaged dimer of MukB heads is short-lived.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:533C01B95B09F881	false	-	sufficient binding region:33-1496|mutation:1435-1435|mutation:272-1262	-	2	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:15422"	uniprotkb:Q7VL95	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213775|imex:IM-12157-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 6A, Supp. Fig. 6|comment:"mukB g;u1435gln mutant is catalytically inactive. Once reacted with ATP, as a result of the separation of MukF C-WHD from MukBEQ, this reaction generated five new complexes  with stoichiomentry 1:4, 1:3, 1:2, 1:1 and 1:0 between MukEF and MukB"|comment:ATP contains a radio-labelled tracer|comment:The wild-type MukB-MukEF-MukB complex was reacted with 10 mM ATP or AMPPNP. In the presence of AMPPNP, this complex underwent the same conversion reaction described in this entry. In contrast the ATP-bound, engaged dimer of MukB heads is short-lived.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:533C01B95B09F881	false	-	-	-	1	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:15422"	uniprotkb:Q7VL94	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213775|imex:IM-12157-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Fig. 6A, Supp. Fig. 6|comment:"mukB g;u1435gln mutant is catalytically inactive. Once reacted with ATP, as a result of the separation of MukF C-WHD from MukBEQ, this reaction generated five new complexes  with stoichiomentry 1:4, 1:3, 1:2, 1:1 and 1:0 between MukEF and MukB"|comment:ATP contains a radio-labelled tracer|comment:The wild-type MukB-MukEF-MukB complex was reacted with 10 mM ATP or AMPPNP. In the presence of AMPPNP, this complex underwent the same conversion reaction described in this entry. In contrast the ATP-bound, engaged dimer of MukB heads is short-lived.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:533C01B95B09F881	false	-	sufficient binding region:358-440	-	1	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q7VL96	uniprotkb:Q7VL94	intact:EBI-2213597|ensemblbacteria:AAP96363	intact:EBI-2213621|ensemblbacteria:AAP96365	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:mukf_haedu(display_long)|uniprotkb:mukF(gene name)|psi-mi:mukF(display_short)|uniprotkb:HD_1585(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213740|imex:IM-12157-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	interpro:IPR033439|interpro:IPR033440|interpro:IPR033441|interpro:IPR005582(Prokaryotic chromosome segregation and condensation protein MukF)|rcsb pdb:3EUJ|rcsb pdb:3EUK|refseq:WP_010945397.1|interpro:IPR038198|interpro:IPR036141|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAP96365(transcript)|ensemblbacteria:HD_1585(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	-	2009/01/27	2014/10/16	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	rogid:y+mevTN3YRV4+Uu49HbF5/ct4JQ233412	intact-crc:AF98320DC064623E|rigid:SYBnHS0xmHKuOqCa4uIg+5zOPRA	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q7VL96	uniprotkb:Q7VL95	intact:EBI-2213597|ensemblbacteria:AAP96363	intact:EBI-2213586|ensemblbacteria:AAP96364	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:muke_haedu(display_long)|uniprotkb:mukE(gene name)|psi-mi:mukE(display_short)|uniprotkb:HD_1584(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213740|imex:IM-12157-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	interpro:IPR007385(Prokaryotic chromosome segregation and condensation protein MukE)|rcsb pdb:3EUK|refseq:WP_010945396.1|interpro:IPR042037|interpro:IPR042038|ensemblbacteria:AAP96364(transcript)|ensemblbacteria:HD_1584(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	-	2009/01/27	2014/10/16	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	rogid:qlc3+KWvZx71oms8xoOpUSJuEZA233412	intact-crc:AF98320DC064623E|rigid:SYBnHS0xmHKuOqCa4uIg+5zOPRA	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
chebi:"CHEBI:15422"	uniprotkb:Q7VL96	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-2213597|ensemblbacteria:AAP96363	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:mukb_haedu(display_long)|uniprotkb:mukB(gene name)|psi-mi:mukB(display_short)|uniprotkb:Structural maintenance of chromosome-related protein(gene name synonym)|uniprotkb:HD_1582(locus name)	psi-mi:"MI:0880"(atpase assay)	Woo et al. (2009)	imex:IM-12157|pubmed:19135891	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:233412(haedu)|taxid:233412("Haemophilus ducreyi (strain 35000HP / ATCC 700724)")	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2213761|imex:IM-12157-10	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR012090(Chromosome partition protein MukB)|interpro:IPR007406(Prokaryotic chromosome segregation and condensation protein MukB, N-terminal)|rcsb pdb:3EUJ|rcsb pdb:3EUK|interpro:IPR032520|refseq:WP_010945395.1|interpro:IPR027417|interpro:IPR042501|ensemblbacteria:AAP96363(transcript)|ensemblbacteria:HD_1582(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009295"(nucleoid)|go:"GO:0030261"(chromosome condensation)|go:"GO:0051301"(cell division)	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Fig. 5A|stimulant:"mukE/mukF(292-443) complex"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/27	2014/10/16	-	rogid:VM+qAdAYTr6ZmOFeORXVUbkEaPI233412	intact-crc:EBE83607C98B63E7	false	-	sufficient binding region:34-1496|mutation:1435-1435	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)