#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8C8R3	uniprotkb:P63260	intact:EBI-774322|intact:EBI-2133064|uniprotkb:Q6PCN2|uniprotkb:Q3TM62|uniprotkb:Q3V2X0|uniprotkb:Q80ZZ7|uniprotkb:Q8BNC1|uniprotkb:Q8C445|uniprotkb:Q8CCV0|intact:EBI-2255612|intact:EBI-8314005|intact:MINT-4115219	intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822	psi-mi:ank2_mouse(display_long)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)	psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2133076|imex:IM-12153-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029340.1|refseq:NP_848770.2|dip:DIP-58645N|mint:Q8C8R3|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001257"(regulation of cation channel activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745	refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608	go:"GO:0043034"(costamere)	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-skeletal-muscle)|taxid:10090(Mus musculus skeletal muscle.)	-	2009/01/06	2014/10/16	rogid:SkB13oxZVcKuMnI8r5ItFIq2pXQ10090	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090	intact-crc:6E96B88F5A32F324|rigid:UGXssTGk2l5/WN4pD0003/VwD/8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P63260	uniprotkb:G5E8K5	intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822	intact:EBI-457262|uniprotkb:G5E8K4|uniprotkb:Q3TSJ8|uniprotkb:Q4U205|uniprotkb:Q4U206|uniprotkb:Q4U256|uniprotkb:Q4U260|uniprotkb:Q61307|uniprotkb:Q8CBN3|uniprotkb:Q8VC68|uniprotkb:O08866|uniprotkb:O08867|uniprotkb:Q61305|uniprotkb:Q61306|uniprotkb:Q61308|uniprotkb:Q61309|uniprotkb:Q61310|intact:EBI-2133089|ensembl:ENSMUSP00000090090|ensembl:ENSMUSP00000138326	psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:ank3_mouse(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2133082|imex:IM-12153-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608	refseq:NP_666117.2|refseq:XP_006513202.1|refseq:NP_033800.2|refseq:NP_733788.2|refseq:NP_733789.1|refseq:NP_733790.2|refseq:NP_733791.2|refseq:NP_733924.2|refseq:NP_733925.2|refseq:NP_733926.2|ensembl:ENSMUSG00000069601(gene)|ensembl:ENSMUST00000092434(transcript)|ensembl:ENSMUST00000182884(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043194"(axon initial segment)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0050808"(synapse organization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|mint:G5E8K5	go:"GO:0043034"(costamere)	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-skeletal-muscle)|taxid:10090(Mus musculus skeletal muscle.)	-	2009/01/06	2014/10/16	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090	rogid:sPFqnXYHQKlR6xjYE/VqOvNFxG010090	intact-crc:2BEA9582B4CF6877|rigid:8hWq74/GzNgZ272u+9YSLvUdR/k	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8C8R3	uniprotkb:Q8CBY8	intact:EBI-774322|intact:EBI-2133064|uniprotkb:Q6PCN2|uniprotkb:Q3TM62|uniprotkb:Q3V2X0|uniprotkb:Q80ZZ7|uniprotkb:Q8BNC1|uniprotkb:Q8C445|uniprotkb:Q8CCV0|intact:EBI-2255612|intact:EBI-8314005|intact:MINT-4115219	intact:EBI-776033|uniprotkb:Q923A0|uniprotkb:Q9D4X0|ensembl:ENSMUSP00000153008	psi-mi:ank2_mouse(display_long)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)	psi-mi:dctn4_mouse(display_long)|uniprotkb:Dynactin subunit p62(gene name synonym)|uniprotkb:Dctn4(gene name)|psi-mi:Dctn4(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134059|imex:IM-12153-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029340.1|refseq:NP_848770.2|dip:DIP-58645N|mint:Q8C8R3|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001257"(regulation of cation channel activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745	refseq:NP_080578.1|refseq:XP_006526252.1|ensembl:ENSMUSG00000024603(gene)|ensembl:ENSMUST00000223984(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001725"(stress fiber)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005869"(dynactin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0030017"(sarcomere)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008603(Dynactin p62)|mint:Q8CBY8|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436	go:"GO:0043034"(costamere)	-	-	figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-skeletal-muscle)|taxid:10090(Mus musculus skeletal muscle.)	-	2009/01/06	2014/10/16	rogid:SkB13oxZVcKuMnI8r5ItFIq2pXQ10090	rogid:ku/Cy0u7rZmYNcJ19nL9Mn6YLYQ10090	intact-crc:2305A7F43A13502C|rigid:nlHLLNO0T8fV0mJwi8zMX/ZZRjo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q01484	uniprotkb:P11532-5	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	intact:EBI-1018651|ensembl:ENSP00000354464	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2133936|imex:IM-12153-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	psi-mi:"MI:0469"(intact)	-	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	figure legend:Fig. 5A, 5B, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	intact-crc:CDE63B9334D44E89|rigid:cfMJOXmrG3Zo4WQIdd+CL/475fE	false	his tag:?-?	glutathione s tranferase tag:n-n|mutation decreasing interaction:267-267|sufficient binding region:1-359	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P11532-5	uniprotkb:Q3T1J5	intact:EBI-1018651|ensembl:ENSP00000354464	intact:EBI-2133962	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:q3t1j5_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2133972|imex:IM-12153-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR000906(ZU5)|interpro:IPR040745|interpro:IPR037971|go:"GO:0007165"(signal transduction)	psi-mi:"MI:0469"(intact)	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	rogid:Rjc66/vNBlk0GhSU3rkNZLn5zc810116	intact-crc:5F19753A3494E0C5|rigid:NSP0uuKbVU39SQuC/wxggsIm7B8	false	glutathione s tranferase tag:n-n|his tag:c-c	his tag:?-?	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q14118	uniprotkb:Q3T1J5	intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000440705|ensembl:ENSP00000442600|ensembl:ENSP00000501140	intact:EBI-2133962	psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:q3t1j5_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2133983|imex:IM-12153-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|ensembl:ENSP00000312435|ensembl:ENSP00000440705|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000442600|ensembl:ENSP00000501140|dip:DIP-40928N|ensembl:ENSG00000173402(gene)|ensembl:ENST00000308775(transcript)|ensembl:ENST00000515359(transcript)|ensembl:ENST00000538711(transcript)|ensembl:ENST00000539901(transcript)|ensembl:ENST00000541308(transcript)|ensembl:ENST00000545947(transcript)|ensembl:ENST00000673708(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665	interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR000906(ZU5)|interpro:IPR040745|interpro:IPR037971|go:"GO:0007165"(signal transduction)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:q+98wmc5ueyzkpOCrold06eukRg9606	rogid:Rjc66/vNBlk0GhSU3rkNZLn5zc810116	intact-crc:769E1C96054254AD|rigid:Yolb/b3UaNb6zPXUvC7zX40BkEE	false	sufficient binding region:776-895|glutathione s tranferase tag:n-n|his tag:c-c	his tag:?-?	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q01484	uniprotkb:Q9UJW0	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	intact:EBI-2134033|uniprotkb:Q8TAN8|uniprotkb:D3DQH0|intact:EBI-2559420|uniprotkb:B3KWW0|uniprotkb:E5RGT5|ensembl:ENSP00000416968	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:dctn4_human(display_long)|uniprotkb:DCTN4(gene name)|psi-mi:DCTN4(display_short)|uniprotkb:Dynactin subunit p62(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134045|imex:IM-12153-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878	refseq:XP_011535946.1|refseq:XP_011535947.1|refseq:NP_001129116.1|refseq:NP_057305.1|refseq:NP_001129115.1|ensembl:ENSG00000132912(gene)|ensembl:ENST00000447998(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005869"(dynactin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0030017"(sarcomere)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008603(Dynactin p62)|mint:Q9UJW0|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rogid:JradQZl06O4u9N3HH+cpvdP05RA9606	intact-crc:F7B72A0CB11BD851|rigid:xeXWnRo/m2f4QLXIXyP9ZMaRq08	false	his tag:?-?	glutathione s tranferase tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P11532-5	uniprotkb:Q01484	intact:EBI-1018651|ensembl:ENSP00000354464	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134070|imex:IM-12153-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878	psi-mi:"MI:0469"(intact)	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	-	figure legend:Supp. Fig. 3|comment:Presence of DAG1 demonstrated by western blot.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	intact-crc:2D4A63EF438A83BE|rigid:83t8Bh5vLLcQTJsskd98YtY6ga0	false	glutathione s tranferase tag:n-n|mutation decreasing interaction:267-267|sufficient binding region:1-359	his tag:?-?	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P11532-5	uniprotkb:Q14118	intact:EBI-1018651|ensembl:ENSP00000354464	intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000440705|ensembl:ENSP00000442600|ensembl:ENSP00000501140	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134070|imex:IM-12153-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|ensembl:ENSP00000312435|ensembl:ENSP00000440705|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000442600|ensembl:ENSP00000501140|dip:DIP-40928N|ensembl:ENSG00000173402(gene)|ensembl:ENST00000308775(transcript)|ensembl:ENST00000515359(transcript)|ensembl:ENST00000538711(transcript)|ensembl:ENST00000539901(transcript)|ensembl:ENST00000541308(transcript)|ensembl:ENST00000545947(transcript)|ensembl:ENST00000673708(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665	psi-mi:"MI:0469"(intact)	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	-	figure legend:Supp. Fig. 3|comment:Presence of DAG1 demonstrated by western blot.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	rogid:q+98wmc5ueyzkpOCrold06eukRg9606	intact-crc:2D4A63EF438A83BE|rigid:83t8Bh5vLLcQTJsskd98YtY6ga0	false	glutathione s tranferase tag:n-n|mutation decreasing interaction:267-267|sufficient binding region:1-359	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P11532-5	uniprotkb:Q14118	intact:EBI-1018651|ensembl:ENSP00000354464	intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000440705|ensembl:ENSP00000442600|ensembl:ENSP00000501140	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134085|imex:IM-12153-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|ensembl:ENSP00000312435|ensembl:ENSP00000440705|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000442600|ensembl:ENSP00000501140|dip:DIP-40928N|ensembl:ENSG00000173402(gene)|ensembl:ENST00000308775(transcript)|ensembl:ENST00000515359(transcript)|ensembl:ENST00000538711(transcript)|ensembl:ENST00000539901(transcript)|ensembl:ENST00000541308(transcript)|ensembl:ENST00000545947(transcript)|ensembl:ENST00000673708(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665	psi-mi:"MI:0469"(intact)	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	-	figure legend:Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	rogid:q+98wmc5ueyzkpOCrold06eukRg9606	intact-crc:938F1FDE9F2F8F7E|rigid:NOg3rL0NCVcDP5oMdPg2AdPZhyE	false	glutathione s tranferase tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P11532-5	uniprotkb:Q3T1J5	intact:EBI-1018651|ensembl:ENSP00000354464	intact:EBI-2133962	psi-mi:p11532-5(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short)|uniprotkb:Dp71ab(isoform synonym)	psi-mi:q3t1j5_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134085|imex:IM-12153-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-295827(dmd_human)|ensembl:ENSG00000198947(gene)|ensembl:ENST00000361471(transcript)	interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR000906(ZU5)|interpro:IPR040745|interpro:IPR037971|go:"GO:0007165"(signal transduction)	psi-mi:"MI:0469"(intact)	isoform-comment:Contains a phosphothreonine at position 340. Contains a phosphoserine at position 348. Contains a phosphoserine at position 344. Contains a phosphothreonine at position 616. Produced by alternative splicing of isoform 12.	-	figure legend:Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:rvvuhY0FxFLNwf10FXFIrSQ7AvQ9606	rogid:Rjc66/vNBlk0GhSU3rkNZLn5zc810116	intact-crc:938F1FDE9F2F8F7E|rigid:NOg3rL0NCVcDP5oMdPg2AdPZhyE	false	glutathione s tranferase tag:n-n|his tag:c-c	his tag:?-?	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q14118	uniprotkb:Q3T1J5	intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000440705|ensembl:ENSP00000442600|ensembl:ENSP00000501140	intact:EBI-2133962	psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:q3t1j5_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0096"(pull down)	Ayalon et al. (2008)	imex:IM-12153|pubmed:19109891	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2134010|imex:IM-12153-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|ensembl:ENSP00000312435|ensembl:ENSP00000440705|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000442600|ensembl:ENSP00000501140|dip:DIP-40928N|ensembl:ENSG00000173402(gene)|ensembl:ENST00000308775(transcript)|ensembl:ENST00000515359(transcript)|ensembl:ENST00000538711(transcript)|ensembl:ENST00000539901(transcript)|ensembl:ENST00000541308(transcript)|ensembl:ENST00000545947(transcript)|ensembl:ENST00000673708(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665	interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR000906(ZU5)|interpro:IPR040745|interpro:IPR037971|go:"GO:0007165"(signal transduction)	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/06	2014/10/16	rogid:q+98wmc5ueyzkpOCrold06eukRg9606	rogid:Rjc66/vNBlk0GhSU3rkNZLn5zc810116	intact-crc:7239FB16DB02D44C|rigid:Yolb/b3UaNb6zPXUvC7zX40BkEE	false	necessary binding region:798-800|glutathione s tranferase tag:n-n|his tag:c-c|mutation disrupting interaction:802-803|mutation decreasing interaction:805-806	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)