#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18065	uniprotkb:Q9C086	intact:EBI-2504392|ensembl:ENSP00000233809|uniprotkb:Q14619|uniprotkb:Q9UCL3	intact:EBI-715611|ensembl:ENSP00000233331	psi-mi:ibp2_human(display_long)|uniprotkb:BP2(gene name synonym)|uniprotkb:IBP2(gene name synonym)|uniprotkb:IGFBP2(gene name)|psi-mi:IGFBP2(display_short)	psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Miyako et al. (2009)	pubmed:19095771|imex:IM-19174	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2504415|imex:IM-19174-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115457(gene)|ensembl:ENST00000233809(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042493"|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012210(Insulin-like growth factor binding protein 2)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|rcsb pdb:2H7T|reactome:R-HSA-381426|go:"GO:0051384"(response to glucocorticoid)|refseq:NP_000588.2|refseq:NP_001300919.1|refseq:NP_001300921.1|refseq:NP_001300922.1	refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)	-	-	-	caution:The  IGFBP2  construct is described as the mature peptide so the signal sequence, as described in the UniProtKB entry, has been removed.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/01	2014/10/16	rogid:jfWXL4O/e6p6Bo6pE+Ygu8Ouw4c9606	rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606	intact-crc:6AE6FA4036905120|rigid:Q1iqt0vtCtGIA0NHkwoCZy+hGwE	false	sufficient binding region:37..37-325	sufficient binding region:127-356	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18065	uniprotkb:Q9C086	intact:EBI-2504392|ensembl:ENSP00000233809|uniprotkb:Q14619|uniprotkb:Q9UCL3	intact:EBI-715611|ensembl:ENSP00000233331	psi-mi:ibp2_human(display_long)|uniprotkb:BP2(gene name synonym)|uniprotkb:IBP2(gene name synonym)|uniprotkb:IGFBP2(gene name)|psi-mi:IGFBP2(display_short)	psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Miyako et al. (2009)	pubmed:19095771|imex:IM-19174	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2504523|imex:IM-19174-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115457(gene)|ensembl:ENST00000233809(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042493"|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012210(Insulin-like growth factor binding protein 2)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|rcsb pdb:2H7T|reactome:R-HSA-381426|go:"GO:0051384"(response to glucocorticoid)|refseq:NP_000588.2|refseq:NP_001300919.1|refseq:NP_001300921.1|refseq:NP_001300922.1	refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)	-	-	-	figure legend:Fig. 1.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/01	2014/10/16	rogid:jfWXL4O/e6p6Bo6pE+Ygu8Ouw4c9606	rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606	intact-crc:107036C2F53488EC|rigid:Q1iqt0vtCtGIA0NHkwoCZy+hGwE	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P18065	uniprotkb:Q9C086	intact:EBI-2504392|ensembl:ENSP00000233809|uniprotkb:Q14619|uniprotkb:Q9UCL3	intact:EBI-715611|ensembl:ENSP00000233331	psi-mi:ibp2_human(display_long)|uniprotkb:BP2(gene name synonym)|uniprotkb:IBP2(gene name synonym)|uniprotkb:IGFBP2(gene name)|psi-mi:IGFBP2(display_short)	psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Miyako et al. (2009)	pubmed:19095771|imex:IM-19174	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2504787|imex:IM-19174-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115457(gene)|ensembl:ENST00000233809(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042493"|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012210(Insulin-like growth factor binding protein 2)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|rcsb pdb:2H7T|reactome:R-HSA-381426|go:"GO:0051384"(response to glucocorticoid)|refseq:NP_000588.2|refseq:NP_001300919.1|refseq:NP_001300921.1|refseq:NP_001300922.1	refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	-	-	figure legend:Fig.2A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-lncap)|taxid:9606(Human caucasian prostate carcinoma)	-	2009/12/01	2014/10/16	rogid:jfWXL4O/e6p6Bo6pE+Ygu8Ouw4c9606	rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606	intact-crc:A5D5C6AE39DFC6FF|rigid:Q1iqt0vtCtGIA0NHkwoCZy+hGwE	false	-	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9C086	uniprotkb:P18065	intact:EBI-715611|ensembl:ENSP00000233331	intact:EBI-2504392|ensembl:ENSP00000233809|uniprotkb:Q14619|uniprotkb:Q9UCL3	psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym)	psi-mi:ibp2_human(display_long)|uniprotkb:BP2(gene name synonym)|uniprotkb:IBP2(gene name synonym)|uniprotkb:IGFBP2(gene name)|psi-mi:IGFBP2(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Miyako et al. (2009)	pubmed:19095771|imex:IM-19174	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2504857|imex:IM-19174-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)	ensembl:ENSG00000115457(gene)|ensembl:ENST00000233809(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042493"|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012210(Insulin-like growth factor binding protein 2)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|rcsb pdb:2H7T|reactome:R-HSA-381426|go:"GO:0051384"(response to glucocorticoid)|refseq:NP_000588.2|refseq:NP_001300919.1|refseq:NP_001300921.1|refseq:NP_001300922.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 3.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-lncap)|taxid:9606(Human caucasian prostate carcinoma)	-	2009/12/01	2014/10/16	rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606	rogid:jfWXL4O/e6p6Bo6pE+Ygu8Ouw4c9606	intact-crc:0D827907C456DE60|rigid:Q1iqt0vtCtGIA0NHkwoCZy+hGwE	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)