#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12815 uniprotkb:P36406 intact:EBI-2349743|uniprotkb:Q8N5B2|uniprotkb:F8VSF9|uniprotkb:Q6PJU7|ensembl:ENSP00000257909 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:troap_human(display_long)|uniprotkb:TROAP(gene name)|psi-mi:TROAP(display_short)|uniprotkb:Trophinin-assisting protein(gene name synonym)|uniprotkb:Trophinin-associated protein(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349748|imex:IM-20259-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536027.1|refseq:NP_001094090.1|refseq:NP_005471.3|refseq:NP_001265253.1|dip:DIP-52951N|ensembl:ENSG00000135451(gene)|ensembl:ENST00000257909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|interpro:IPR026133|mint:Q12815 refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9+3f9EdjzudEOEIYnDMmZGrjjKA9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:C9B8B4EF3E6AED5F|rigid:xTDE7aOjCGQrrPsiR1YNDOoGwpM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96EZ8 uniprotkb:Q9Y3C0 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349752|imex:IM-20259-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 intact-crc:B3C10858D6381740|rigid:/0LfZB/nt59LYnnK+9S0COGeAnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96EZ8 uniprotkb:Q86WP2 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-2349758|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285|ensembl:ENSP00000421202 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349756|imex:IM-20259-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 ensembl:ENST00000264779|ensembl:ENSP00000264779|ensembl:ENSP00000421202|ensembl:ENST00000511209|ensembl:ENSP00000422337|ensembl:ENST00000514387|ensembl:ENSP00000421709|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|ensembl:ENSG00000062194(gene)|ensembl:ENST00000506184(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028128|mint:Q86WP2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606 intact-crc:8AF09B10F7844FA4|rigid:YI2UjYAFVOm7hI6GX7+cHXVXkHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96EZ8 uniprotkb:Q96CN9 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349769|imex:IM-20259-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 intact-crc:A7CA11C607C59C24|rigid:WHKXHUV8FtPwmP19ywyD6xCK9Po false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q9UI95 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349773|imex:IM-20259-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:57EE58AD71C14258|rigid:PlS7fGlPgEuGtemXGj+bRQVWM58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60506 uniprotkb:Q9NR22 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349777|imex:IM-20259-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 intact-crc:D014E77C9D048E58|rigid:V0LMA3aDPAmjPU/edNJJiSTnSHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q9UI14 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349781|imex:IM-20259-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:856EEDDA98CABBE3|rigid:aeSpFjgE/USVxzIc2cNzNfpW63s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75886 uniprotkb:O95630 intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904 intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864 psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym) psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349785|imex:IM-20259-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005834.4|ensembl:ENSG00000115145(gene)|ensembl:ENST00000263904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729 refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606 rogid:JUvszgPz9rog/OEpmABJ295BaLw9606 intact-crc:FCB76B7D64CFEAAE|rigid:8o6NFuNsWkLxC6kcCKmnj1qFBeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NTK1 uniprotkb:P36406 intact:EBI-742731|uniprotkb:Q76MX8|uniprotkb:O94997|uniprotkb:Q5T735|ensembl:ENSP00000298295|uniprotkb:B2R6A1 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:depp1_human(display_long)|uniprotkb:DEPP1(gene name)|psi-mi:DEPP1(display_short)|uniprotkb:C10orf10(gene name synonym)|uniprotkb:DEPP(gene name synonym)|uniprotkb:Decidual protein induced by progesterone(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fasting-induced gene protein(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349793|imex:IM-20259-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008952.1|ensembl:ENSG00000165507(gene)|ensembl:ENST00000298295(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR020133 refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dXIt8uYiDcsvDPGDjY0UZwwrsTw9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:E49D2CE711FE079E|rigid:AWoumXlrHl+R0tmbjYA/ul9s31U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95630 uniprotkb:Q15645 intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349789|imex:IM-20259-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JUvszgPz9rog/OEpmABJ295BaLw9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:B20E0D0AE26DE3DF|rigid:Wexod88ov5GqjGI6C7lU83GdbAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q00587 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744130|uniprotkb:Q96GN1|uniprotkb:A8K825|ensembl:ENSP00000249014 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:borg5_human(display_long)|uniprotkb:Binder of Rho GTPases 5(gene name synonym)|uniprotkb:Serum protein MSE55(gene name synonym)|uniprotkb:CEP1(gene name synonym)|uniprotkb:MSE55(gene name synonym)|uniprotkb:CDC42EP1(gene name)|psi-mi:CDC42EP1(display_short)|uniprotkb:BORG5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349797|imex:IM-20259-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_689449.1|refseq:XP_006724170.1|refseq:XP_006724171.1|refseq:XP_006724172.1|ensembl:ENSG00000128283(gene)|ensembl:ENST00000249014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_016884030.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Ros/Dvfb6rdmhUyT755WtSswQjQ9606 intact-crc:70B71FAE3D3564BC|rigid:IVC+j2DJfCgXYYGgEYlXves5+k4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12841 uniprotkb:Q92624 intact:EBI-2349801|uniprotkb:Q549Z0|uniprotkb:A8K523|uniprotkb:B4DTT5|uniprotkb:D3DN90|ensembl:ENSP00000295633 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:fstl1_human(display_long)|uniprotkb:FSTL1(gene name)|psi-mi:FSTL1(display_short)|uniprotkb:FRP(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349806|imex:IM-20259-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009016.1|ensembl:ENSG00000163430(gene)|ensembl:ENST00000295633(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058|reactome:R-HSA-201451|reactome:R-HSA-381426|reactome:R-HSA-8957275 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:2Y10WyTpml76Ksjw+X7dXUozFg09606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:8F5DDC470C234A37|rigid:fLIzrpHxGAdhl7FQBSB5LZ6uQAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36406 uniprotkb:Q9UNA4 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-741774|ensembl:ENSP00000462664|uniprotkb:Q8N590|uniprotkb:Q9H0S1|uniprotkb:Q9NYH6 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:poli_human(display_long)|uniprotkb:Eta2(gene name synonym)|uniprotkb:RAD30 homolog B(gene name synonym)|uniprotkb:POLI(gene name)|psi-mi:POLI(display_short)|uniprotkb:RAD30B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349810|imex:IM-20259-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW rcsb pdb:1T3N|rcsb pdb:1ZET|rcsb pdb:2ALZ|rcsb pdb:2DPI|rcsb pdb:2DPJ|rcsb pdb:2FLL|rcsb pdb:2FLN|rcsb pdb:2FLP|rcsb pdb:2KHU|rcsb pdb:2KHW|rcsb pdb:2KTF|rcsb pdb:2L0F|rcsb pdb:2L0G|rcsb pdb:2MBB|rcsb pdb:3EPG|rcsb pdb:3EPI|rcsb pdb:3G6V|rcsb pdb:3G6X|rcsb pdb:3G6Y|rcsb pdb:3GV5|rcsb pdb:3GV7|rcsb pdb:3GV8|rcsb pdb:3H40|rcsb pdb:3H4B|rcsb pdb:3H4D|ensembl:ENSG00000101751(gene)|ensembl:ENST00000579534(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0019985"(translesion synthesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR017961|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|mint:Q9UNA4|refseq:NP_009126.2|rcsb pdb:3NGD|rcsb pdb:3OSN|rcsb pdb:3Q8P|rcsb pdb:3Q8Q|rcsb pdb:3Q8R|rcsb pdb:3Q8S|rcsb pdb:4EBC|rcsb pdb:4EBD|rcsb pdb:4EBE|rcsb pdb:4EYI|rcsb pdb:4FS1|rcsb pdb:4FS2|rcsb pdb:5KT2|rcsb pdb:5KT3|rcsb pdb:5KT4|rcsb pdb:5KT5|rcsb pdb:5KT6|rcsb pdb:5KT7|rcsb pdb:5ULW|rcsb pdb:5ULX|reactome:R-HSA-5656121|reactome:R-HSA-5656169|rcsb pdb:4EYH - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:iH6WfDK+UIzw5XQSHo9wWSfnrJU9606 intact-crc:7FF1652F35B998B2|rigid:cLSSsY1itcdcZ+0Wn1YEettlLTw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q9UNA4 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-741774|ensembl:ENSP00000462664|uniprotkb:Q8N590|uniprotkb:Q9H0S1|uniprotkb:Q9NYH6 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:poli_human(display_long)|uniprotkb:Eta2(gene name synonym)|uniprotkb:RAD30 homolog B(gene name synonym)|uniprotkb:POLI(gene name)|psi-mi:POLI(display_short)|uniprotkb:RAD30B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349814|imex:IM-20259-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 rcsb pdb:1T3N|rcsb pdb:1ZET|rcsb pdb:2ALZ|rcsb pdb:2DPI|rcsb pdb:2DPJ|rcsb pdb:2FLL|rcsb pdb:2FLN|rcsb pdb:2FLP|rcsb pdb:2KHU|rcsb pdb:2KHW|rcsb pdb:2KTF|rcsb pdb:2L0F|rcsb pdb:2L0G|rcsb pdb:2MBB|rcsb pdb:3EPG|rcsb pdb:3EPI|rcsb pdb:3G6V|rcsb pdb:3G6X|rcsb pdb:3G6Y|rcsb pdb:3GV5|rcsb pdb:3GV7|rcsb pdb:3GV8|rcsb pdb:3H40|rcsb pdb:3H4B|rcsb pdb:3H4D|ensembl:ENSG00000101751(gene)|ensembl:ENST00000579534(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0019985"(translesion synthesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR017961|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|mint:Q9UNA4|refseq:NP_009126.2|rcsb pdb:3NGD|rcsb pdb:3OSN|rcsb pdb:3Q8P|rcsb pdb:3Q8Q|rcsb pdb:3Q8R|rcsb pdb:3Q8S|rcsb pdb:4EBC|rcsb pdb:4EBD|rcsb pdb:4EBE|rcsb pdb:4EYI|rcsb pdb:4FS1|rcsb pdb:4FS2|rcsb pdb:5KT2|rcsb pdb:5KT3|rcsb pdb:5KT4|rcsb pdb:5KT5|rcsb pdb:5KT6|rcsb pdb:5KT7|rcsb pdb:5ULW|rcsb pdb:5ULX|reactome:R-HSA-5656121|reactome:R-HSA-5656169|rcsb pdb:4EYH - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:iH6WfDK+UIzw5XQSHo9wWSfnrJU9606 intact-crc:A044ACE41166141D|rigid:nDXE/GzIBTHq8pYnx33WFnPXl68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96PV6 uniprotkb:Q96MA1 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349818|imex:IM-20259-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 intact-crc:86C9FCF1F9EBF03F|rigid:vXtXnuzj04qq7RsfxBxMGZg3H/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NDC0 uniprotkb:Q96PV6 intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349822|imex:IM-20259-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653 refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:CX220vB2TjggPEso5CHNUVzl79g9606 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 intact-crc:106B640467AAD7A0|rigid:kf6+zGwWj6wA5X9apQRZ8E02ads false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q96A09 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-752030|ensembl:ENSP00000289166 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:tet5b_human(display_long)|uniprotkb:TENT5B(gene name)|psi-mi:TENT5B(display_short)|uniprotkb:FAM46B(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349826|imex:IM-20259-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_443175.2|ensembl:ENSG00000158246(gene)|ensembl:ENST00000289166(transcript)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:hcI1m66Kt1B5RS3kqXhFmu0lNrg9606 intact-crc:4683FA356944007B|rigid:eGyMUfqIh9SUEwWe+pyqE9+J7SY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q969Q4 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-751892|ensembl:ENSP00000282026 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:arl11_human(display_long)|uniprotkb:ADP-ribosylation factor-like tumor suppressor protein 1(gene name synonym)|uniprotkb:ARL11(gene name)|psi-mi:ARL11(display_short)|uniprotkb:ARLTS1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349830|imex:IM-20259-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_612459.1|refseq:XP_005266310.1|ensembl:ENSG00000152213(gene)|ensembl:ENST00000282026(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:8Cdo1tj4uifARGdcn7/lC76OAqU9606 intact-crc:667AF64B32327674|rigid:6Lq9jyKNeoiQsbN2deC9FsjRcPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QF0 uniprotkb:Q8TBN0 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349838|imex:IM-20259-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 intact-crc:5C3F493E16EE96B5|rigid:ya6KnFVg/TG0Xjyx/I7xBdiqEmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q8N1L9 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-742695|uniprotkb:Q96EH4|uniprotkb:Q8NAF4|intact:EBI-945729|uniprotkb:Q8NAL8|ensembl:ENSP00000301887|uniprotkb:D9IC56 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:batf2_human(display_long)|uniprotkb:BATF2(gene name)|psi-mi:BATF2(display_short)|uniprotkb:Suppressor of AP-1 regulated by IFN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349834|imex:IM-20259-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_612465.3|refseq:NP_001287736.1|refseq:NP_001287737.1|ensembl:ENSG00000168062(gene)|ensembl:ENST00000301887(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029857|dip:DIP-48662N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:uL+kdibEI8CV/k5zjBeezZNzeAY9606 intact-crc:ABCCA1566698A1EA|rigid:mMi45yWuLqK8c/5JjGQ7u2CD2rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96C03 uniprotkb:Q9UI14 intact:EBI-750153|uniprotkb:Q6ZRD4|uniprotkb:Q96N07|uniprotkb:J3KPT3|ensembl:ENSP00000323591|ensembl:ENSP00000491181 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:mid49_human(display_long)|uniprotkb:MIEF2(gene name)|psi-mi:MIEF2(display_short)|uniprotkb:MID49(gene name synonym)|uniprotkb:Mitochondrial elongation factor 2(gene name synonym)|uniprotkb:SMCR7(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 49 kDa(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349842|imex:IM-20259-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138372.1|refseq:NP_631901.2|refseq:NP_683684.2|ensembl:ENSG00000177427(gene)|ensembl:ENSG00000284495(gene)|ensembl:ENST00000323019(transcript)|ensembl:ENST00000640122(transcript)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:5WP9 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6/vE89OUApM4jmEn3byKeAkZKEw9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:770A8A573F2C579E|rigid:7HYI8R5qBD/kABGEVQSVT/IZeMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27658 uniprotkb:Q6UY14 intact:EBI-747133|uniprotkb:Q96D07|uniprotkb:Q53XI6|uniprotkb:D3DN42|ensembl:ENSP00000261037|ensembl:ENSP00000273342|ensembl:ENSP00000498483 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 psi-mi:co8a1_human(display_long)|uniprotkb:Endothelial collagen(gene name synonym)|uniprotkb:COL8A1(gene name)|psi-mi:COL8A1(display_short)|uniprotkb:C3orf7(gene name synonym) psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349846|imex:IM-20259-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001841.2|refseq:NP_065084.2|ensembl:ENSG00000144810(gene)|ensembl:ENST00000261037(transcript)|ensembl:ENST00000273342(transcript)|ensembl:ENST00000652472(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005591"(collagen type VIII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|mint:P27658|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-8948216|go:"GO:0030198"(extracellular matrix organization) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:7doqmNP4HDwd5sPaFgMCUHg4lLA9606 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 intact-crc:19420D6FD90728A2|rigid:b/Rodlv+qwUVqVvD96DGt0cMaMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WWR8 uniprotkb:Q99750 intact:EBI-746964|uniprotkb:Q96D64|uniprotkb:A8K056|ensembl:ENSP00000375830|ensembl:ENSP00000384804|ensembl:ENSP00000385402|ensembl:ENSP00000478409|ensembl:ENSP00000483726|ensembl:ENSP00000486602|uniprotkb:J3KNJ5 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:neur4_human(display_long)|uniprotkb:N-acetyl-alpha-neuraminidase 4(gene name synonym)|uniprotkb:NEU4(gene name)|psi-mi:NEU4(display_short)|uniprotkb:LP5125(orf name) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349850|imex:IM-20259-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161072.1|refseq:NP_001161073.1|refseq:NP_001161074.1|refseq:NP_542779.2|ensembl:ENSG00000204099(gene)|ensembl:ENSG00000277926(gene)|ensembl:ENST00000391969(transcript)|ensembl:ENST00000405370(transcript)|ensembl:ENST00000407683(transcript)|ensembl:ENST00000618866(transcript)|ensembl:ENST00000621851(transcript)|ensembl:ENST00000630923(transcript)|go:"GO:0004308"(exo-alpha-sialidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019866"(organelle inner membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0052794"("exo-alpha-(2->3)-sialidase activity")|go:"GO:0052795"("exo-alpha-(2->6)-sialidase activity")|go:"GO:0052796"("exo-alpha-(2->8)-sialidase activity")|interpro:IPR026856|interpro:IPR026946|interpro:IPR036278|reactome:R-HSA-1660662|reactome:R-HSA-4085001|interpro:IPR011040(Neuraminidase)|refseq:NP_001161071.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/7pEb6MVBog4FRBxjxtwP8+E3TM9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:490C518963CB2B37|rigid:2ns3WvoQUMgYnR2FUWvbX/VIwk4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96Q35 uniprotkb:O00204 intact:EBI-750451|intact:EBI-1755548|uniprotkb:G5E9S3|uniprotkb:Q53TT6|uniprotkb:Q8N1B6|ensembl:ENSP00000286190|ensembl:ENSP00000385098 intact:EBI-749441|uniprotkb:O00205|uniprotkb:O75814|ensembl:ENSP00000201586 psi-mi:facc1_human(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym) psi-mi:st2b1_human(display_long)|uniprotkb:Alcohol sulfotransferase(gene name synonym)|uniprotkb:Hydroxysteroid sulfotransferase 2(gene name synonym)|uniprotkb:SULT2B1(gene name)|psi-mi:SULT2B1(display_short)|uniprotkb:HSST2(gene name synonym)|uniprotkb:Sulfotransferase family 2B member 1(gene name synonym)|uniprotkb:Sulfotransferase family cytosolic 2B member 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349854|imex:IM-20259-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120863.1|refseq:NP_631902.2|refseq:NP_001276922.1|ensembl:ENSG00000155749(gene)|ensembl:ENST00000286190(transcript)|ensembl:ENST00000405148(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036126"(sperm flagellum)|interpro:IPR026674 refseq:NP_004596.2|refseq:NP_814444.1|ensembl:ENSG00000088002(gene)|ensembl:ENST00000201586(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004027"(alcohol sulfotransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015485"(cholesterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0050294"(steroid sulfotransferase activity)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0051923"(sulfation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990239"(steroid hormone binding)|interpro:IPR000863(Sulphotransferase)|interpro:IPR027417|rcsb pdb:1Q1Q|rcsb pdb:1Q1Z|rcsb pdb:1Q20|rcsb pdb:1Q22|reactome:R-HSA-156584 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:duJOMHCkILW7xWaQjgpDCLSHovs9606 rogid:mon2RxBJKz7A1ArPr/poZuguEXE9606 intact-crc:95A59F0509EFA058|rigid:rMmNiL5ghcVdqK2jxFzMx4ssp5Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WV99 uniprotkb:Q15038 intact:EBI-747823|uniprotkb:Q8NB98|ensembl:ENSP00000289528|ensembl:ENSP00000386898|ensembl:ENSP00000411334 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:zfn2b_human(display_long)|uniprotkb:ZFAND2B(gene name)|psi-mi:ZFAND2B(display_short)|uniprotkb:AIRAPL(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein-like protein(gene name synonym) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349858|imex:IM-20259-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620157.1|refseq:NP_001257928.1|refseq:NP_001257927.1|refseq:XP_016858857.1|ensembl:ENSG00000158552(gene)|ensembl:ENST00000289528(transcript)|ensembl:ENST00000409336(transcript)|ensembl:ENST00000444522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR035896|rcsb pdb:1X4V ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5a4FVFykky/RfCZ4r5cHDhtjh/Q9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:5FC2B47C29E5830B|rigid:OGUYM3h+jQ7zEEblbLmtHVUzvm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NFR7 uniprotkb:P21673 intact:EBI-2349862|uniprotkb:Q96LM2|uniprotkb:Q3B7I4|uniprotkb:Q3KR41|uniprotkb:Q53TM6|uniprotkb:Q3B7I3|uniprotkb:Q4ZG23|uniprotkb:Q96BN5|uniprotkb:Q4ZG12|uniprotkb:F5H839|ensembl:ENSP00000283233 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:cc148_human(display_long)|uniprotkb:CCDC148(gene name)|psi-mi:CCDC148(display_short) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349874|imex:IM-20259-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620158.3|refseq:NP_001288613.1|refseq:NP_001288614.1|ensembl:ENSG00000153237(gene)|ensembl:ENST00000283233(transcript)|interpro:IPR039902 ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NjaVl6Tg5pjMw8pimdrrDArtDgI9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:F8625C1A03D3671D|rigid:L+ujniHJf/tEgnfK8wbiVe/haKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21964 uniprotkb:Q15645 intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349878|imex:IM-20259-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:DB11C0F4FCACDA41|rigid:844ue2UYWAiJOctHI8nJsDqhJp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92624 uniprotkb:A1XBS5 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-2349888|uniprotkb:Q96L09|uniprotkb:Q6AHW7|uniprotkb:A1XBS4|uniprotkb:Q8N8R1|uniprotkb:Q32ND3|ensembl:ENSP00000429367 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:fa92a_human(display_long)|uniprotkb:FAM92A(gene name)|psi-mi:FAM92A(display_short)|uniprotkb:FAM92A1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349886|imex:IM-20259-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_001269963.1|refseq:NP_660312.2|ensembl:ENSG00000188343(gene)|ensembl:ENST00000518322(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005814"(centriole)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0061024"(membrane organization)|go:"GO:0097546"(ciliary base)|go:"GO:0097749"(membrane tubulation)|interpro:IPR009602(Protein of unknown function DUF1208)|interpro:IPR027267|interpro:IPR035590|mint:A1XBS5 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:okcFZHR4G4vduKkWaZ0jXyRVZmY9606 intact-crc:EC02316646A65CA4|rigid:iAA9Q26/6HhGthuOhDYK1O8Ee+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q8IVS8 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-748515|uniprotkb:Q0P630|uniprotkb:Q2EZ43|uniprotkb:Q6Y2K6|uniprotkb:Q7Z6G5|uniprotkb:Q86YR8|uniprotkb:Q8TED2|uniprotkb:Q8WTY2|ensembl:ENSP00000389175 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:glctk_human(display_long)|uniprotkb:HBeAg-binding protein 4(gene name synonym)|uniprotkb:GLYCTK(gene name)|psi-mi:GLYCTK(display_short)|uniprotkb:HBEBP4(gene name synonym)|uniprotkb:LP5910(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349882|imex:IM-20259-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001138423.1|refseq:NP_660305.2|ensembl:ENSG00000168237(gene)|ensembl:ENST00000436784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008887"(glycerate kinase activity)|go:"GO:0061624"(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|interpro:IPR007835(MOFRL)|interpro:IPR025286|interpro:IPR038614|interpro:IPR039760|reactome:R-HSA-70350 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:bllfV0CGOer8LrNYQtIm+i+mhu09606 intact-crc:87D56C7F83A148BF|rigid:oOnPGCcHbKrCP3VB8RzNujt7cqQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12277 uniprotkb:Q96DX5 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349903|imex:IM-20259-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 intact-crc:FC51959E70E3A485|rigid:EV7wBgPng3pGRJY55LiCSlvdf6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NWT6 uniprotkb:Q96DX5 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349907|imex:IM-20259-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 intact-crc:B197F6C7F486A518|rigid:zgfqTugrhpF4G0yekOH+6cGfeJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:P53672 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-750444|uniprotkb:Q9Y562|uniprotkb:Q4ZFX0|ensembl:ENSP00000295728|ensembl:ENSP00000375946 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:crba2_human(display_long)|uniprotkb:Beta-A2 crystallin(gene name synonym)|uniprotkb:CRYBA2(gene name)|psi-mi:CRYBA2(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349911|imex:IM-20259-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_476434.1|refseq:NP_476435.1|ensembl:ENSG00000163499(gene)|ensembl:ENST00000295728(transcript)|ensembl:ENST00000392096(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P53672 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:/WkdaQ4LTxa9mpIiOwVuhd375mE9606 intact-crc:DFB25DF41AE7BF32|rigid:Oz76y1wn3BXN/kllwUVpS+XJm8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UBX3 uniprotkb:Q99750 intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349915|imex:IM-20259-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:9D42C309E5D572F9|rigid:Ld3t/lXV+Iil7z3Vet3JzPctoiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBN0 uniprotkb:Q8IYI6 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349923|imex:IM-20259-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 intact-crc:6FCC33F9926EB5E8|rigid:g5pB71tutJAs/iak9BHftmxAMEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:Q8IYI6 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349919|imex:IM-20259-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 intact-crc:39653791063B3572|rigid:toK5zaQZX/7NDJmS4VgAwTxdlZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IYI6 uniprotkb:Q5JST6 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349935|imex:IM-20259-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 intact-crc:5D81FD4EC0B7D297|rigid:7N1ZBbMp/Q8qXAcKX0H8tH1kAxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13498 uniprotkb:Q99750 intact:EBI-986058|uniprotkb:Q14090|uniprotkb:Q9BR72|ensembl:ENSP00000261623 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:cy24a_human(display_long)|uniprotkb:p22 phagocyte B-cytochrome(gene name synonym)|uniprotkb:Neutrophil cytochrome b 22 kDa polypeptide(gene name synonym)|uniprotkb:p22-phox(gene name synonym)|uniprotkb:"Cytochrome b(558) alpha chain"(gene name synonym)|uniprotkb:Cytochrome b558 subunit alpha(gene name synonym)|uniprotkb:Superoxide-generating NADPH oxidase light chain subunit(gene name synonym)|uniprotkb:CYBA(gene name)|psi-mi:CYBA(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349939|imex:IM-20259-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000051523(gene)|ensembl:ENST00000261623(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001725"(stress fiber)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003106"(negative regulation of glomerular filtration by angiotensin)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014823"(response to activity)|go:"GO:0014895"(smooth muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020037"(heme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904845"(cellular response to L-glutamine)|interpro:IPR007732(Cytochrome b558 alpha-subunit)|mint:P13498|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9673324|refseq:NP_000092.2|dip:DIP-37650N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:FviZIB2lWLr0GrH9y2gxAA6mgCg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:6A52B7F5884589E3|rigid:B2I6KMLxUrs9XZmBovNk5ydDemU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q96LL4 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-751596|uniprotkb:Q96LJ9|ensembl:ENSP00000297324 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:ch048_human(display_long)|uniprotkb:C8orf48(gene name)|psi-mi:C8orf48(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349943|imex:IM-20259-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001007091.1|ensembl:ENSG00000164743(gene)|ensembl:ENST00000297324(transcript)|interpro:IPR027932|mint:Q96LL4 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:JPB4E+42Jc1w9k0ExNOu0GOi9AQ9606 intact-crc:1B0021C13B5AB402|rigid:B6uKVGDO+lpHbyFHRtxht5l9cBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06730 uniprotkb:Q9NRA8 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349947|imex:IM-20259-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 intact-crc:16AFD6E9542EC8D4|rigid:Dc1h8DyCQXhYWB2PyiFTWMWOlMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9L3 uniprotkb:O00423 intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424|ensembl:ENSP00000357202 intact:EBI-751327|uniprotkb:Q86U15|uniprotkb:Q8N536|uniprotkb:Q8N5C4|uniprotkb:Q8WWL6|ensembl:ENSP00000262233 psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name) psi-mi:emal1_human(display_long)|uniprotkb:EML1(gene name)|psi-mi:EML1(display_short)|uniprotkb:EMAP1(gene name synonym)|uniprotkb:EMAPL(gene name synonym)|uniprotkb:EMAPL1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349951|imex:IM-20259-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|reactome:R-HSA-6791226|interpro:IPR037433|mint:Q9H9L3|ensembl:ENSG00000143319(gene)|ensembl:ENST00000313146(transcript)|ensembl:ENST00000368219(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034933|interpro:IPR036397 refseq:NP_001008707.1|refseq:NP_004425.2|ensembl:ENSG00000066629(gene)|ensembl:ENST00000262233(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:O00423|rcsb pdb:4CI8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606 rogid:hfGdCoFa3Miii6W/ozQuZ2cFiHs9606 intact-crc:FEF77C67F1931B7B|rigid:zxfJsH5baonkkTZNrQuABN8QN0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92624 uniprotkb:Q6ZMV9 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-751100|uniprotkb:Q2MDE3|uniprotkb:Q2MDE4|uniprotkb:Q5T8J6|uniprotkb:Q6ZWE3|uniprotkb:Q86T87|uniprotkb:Q8WTV4|ensembl:ENSP00000287152 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:kif6_human(display_long)|uniprotkb:KIF6(gene name)|psi-mi:KIF6(display_short)|uniprotkb:C6orf102(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349955|imex:IM-20259-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_659464.3|refseq:XP_011512661.1|refseq:NP_001275953.1|ensembl:ENSG00000164627(gene)|ensembl:ENST00000287152(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:1990939" - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:LuGQTWtwbNjMg332rMN2II5k6yI9606 intact-crc:FEC482A114D29A98|rigid:BJbbPgetU8Xg9sgQte1HG7b3FSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07332 uniprotkb:Q99750 intact:EBI-1055635|uniprotkb:B4DUD0|uniprotkb:E9PC94|uniprotkb:E9PC95|uniprotkb:Q2VXS7|uniprotkb:Q2VXS8|uniprotkb:Q2VXT0|uniprotkb:Q6GTU5|uniprotkb:B2R6E6|ensembl:ENSP00000331504 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:fes_human(display_long)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:p93c-fes(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349959|imex:IM-20259-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137255.1|refseq:NP_001137256.1|refseq:NP_001137257.1|refseq:NP_001996.1|refseq:XP_005254937.1|refseq:XP_005254939.1|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|mint:P07332|rcsb pdb:1WQU|rcsb pdb:2DCR|rcsb pdb:3BKB|rcsb pdb:3CBL|rcsb pdb:3CD3|rcsb pdb:4DYL|rcsb pdb:4E93|rcsb pdb:6JMF|reactome:R-HSA-1433557|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|ensembl:ENSG00000182511(gene)|ensembl:ENST00000328850(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|refseq:XP_016877494.1|refseq:XP_016877495.1|refseq:XP_016877496.1|refseq:XP_016877497.1|refseq:XP_016877498.1|refseq:XP_016877499.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:F3632F20D99AB673|rigid:O80QLi419U1OmSWaq08zbTGzMak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62070 uniprotkb:Q13671 intact:EBI-491037|uniprotkb:P17082|uniprotkb:B2R9Z3|uniprotkb:B7Z6C4|uniprotkb:B7Z7H6|ensembl:ENSP00000256196|uniprotkb:B7Z5Z2 intact:EBI-366017|uniprotkb:O15010|uniprotkb:Q00427|uniprotkb:Q96CC8|ensembl:ENSP00000310406 psi-mi:rras2_human(display_long)|uniprotkb:Ras-like protein TC21(gene name synonym)|uniprotkb:Teratocarcinoma oncogene(gene name synonym)|uniprotkb:RRAS2(gene name)|psi-mi:RRAS2(display_short)|uniprotkb:TC21(gene name synonym) psi-mi:rin1_human(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)|uniprotkb:Ras inhibitor JC99(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349963|imex:IM-20259-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036382.2|refseq:NP_001096139.1|refseq:NP_001170786.1|refseq:NP_001170785.1|ensembl:ENSG00000133818(gene)|ensembl:ENST00000256196(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:2ERY|reactome:R-HSA-9696273 ensembl:ENSG00000174791(gene)|ensembl:ENST00000311320(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR036860|interpro:IPR037191|reactome:R-HSA-8876198|refseq:NP_004283.2|dip:DIP-117N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WW/YiKaC5t0Qy03E7LQTzpIP9BY9606 rogid:oj/ZbyM0Oqe0wDMlFbJHCtGzMwA9606 intact-crc:8B521FDC545AAA5B|rigid:VFn+jhdcLcBpZRY8EN4sYzkG3+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WV24 uniprotkb:Q99750 intact:EBI-738731|uniprotkb:Q15184|uniprotkb:Q2TAN2|uniprotkb:Q9NZ17|uniprotkb:A1A4G9|ensembl:ENSP00000266671|ensembl:ENSP00000480767 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:phla1_human(display_long)|uniprotkb:PHLDA1(gene name)|psi-mi:PHLDA1(display_short)|uniprotkb:T-cell death-associated gene 51 protein(gene name synonym)|uniprotkb:Apoptosis-associated nuclear protein(gene name synonym)|uniprotkb:Proline- and histidine-rich protein(gene name synonym)|uniprotkb:Proline- and glutamine-rich protein(gene name synonym)|uniprotkb:PHRIP(gene name synonym)|uniprotkb:TDAG51(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349967|imex:IM-20259-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031376.3|ensembl:ENSG00000139289(gene)|ensembl:ENST00000266671(transcript)|ensembl:ENST00000619060(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045210"(FasL biosynthetic process)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR042832|reactome:R-HSA-8854521 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NS+bTnhkGzSYrQNsSRqehTkl0809606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:48A36334FC732C32|rigid:wpXo1PbEWl+IPJnw58U5hd6SZ7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:O94907 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-742864|uniprotkb:B2RC19|ensembl:ENSP00000363081 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:dkk1_human(display_long)|uniprotkb:SK(gene name synonym)|uniprotkb:DKK1(gene name)|psi-mi:DKK1(display_short)|uniprotkb:UNQ492/PRO1008(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349971|imex:IM-20259-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_036374.1|interpro:IPR039863|rcsb pdb:3S2K|rcsb pdb:3S8V|rcsb pdb:3SOQ|rcsb pdb:5FWW|rcsb pdb:5GJE|reactome:R-HSA-201681|reactome:R-HSA-3772470|reactome:R-HSA-5339717|ensembl:ENSG00000107984(gene)|ensembl:ENST00000373970(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0008083"(growth factor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042662"(negative regulation of mesodermal cell fate specification)|go:"GO:0042663"(regulation of endodermal cell fate specification)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045813"(positive regulation of Wnt signaling pathway, calcium modulating pathway)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060173"(limb development)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098883"(synapse pruning)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901296"(negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1904338"(regulation of dopaminergic neuron differentiation)|go:"GO:1904723"(negative regulation of Wnt-Frizzled-LRP5/6 complex assembly)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|dip:DIP-46461N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:OOYhVQDXaaC6AbdFdUKMCjB9L1M9606 intact-crc:84472D50D200F0BF|rigid:5JAgny2PE5pYbkDE/E3/EWXIuQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BQ70 uniprotkb:P21673 intact:EBI-745182|uniprotkb:Q2MK75|uniprotkb:Q9UPV3|ensembl:ENSP00000263346|ensembl:ENSP00000491638 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:tcf25_human(display_long)|uniprotkb:Nuclear localized protein 1(gene name synonym)|uniprotkb:TCF25(gene name)|psi-mi:TCF25(display_short)|uniprotkb:KIAA1049(gene name synonym)|uniprotkb:NULP1(gene name synonym)|uniprotkb:FKSG26(orf name) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349975|imex:IM-20259-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055787.1|ensembl:ENSG00000141002(gene)|ensembl:ENST00000263346(transcript)|ensembl:ENST00000640279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:1990112"(RQC complex)|interpro:IPR006994(Basic helix-loop-helix, Nulp1-type)|interpro:IPR011990(Tetratricopeptide-like helical) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+UEKIIV2LaFWrqJiOWgGU74ITVM9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:C629EF71541583EF|rigid:T4Y21e1OdaoW0M4QBcx9qdnLta0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:Q96HL7 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-749393 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:q96hl7_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349979|imex:IM-20259-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 interpro:IPR019749|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR029071|interpro:IPR030691|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR035963 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:8FzDjTTcZeOZDZkuoLZy0pjwuKc9606 intact-crc:F007DDA0FE7E5B7B|rigid:LkCYL8wTLNPVAANGkxOsK104AqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14687 uniprotkb:Q9P2K3 intact:EBI-372619|uniprotkb:Q8IY61|uniprotkb:Q96GA4|uniprotkb:Q9BW09|uniprotkb:D3DUM4|ensembl:ENSP00000253458 intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972 psi-mi:gse1_human(display_long)|uniprotkb:GSE1(gene name)|psi-mi:GSE1(display_short)|uniprotkb:KIAA0182(gene name synonym) psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349983|imex:IM-20259-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127945.1|refseq:NP_055430.1|refseq:NP_001265113.1|ensembl:ENSG00000131149(gene)|ensembl:ENST00000253458(transcript)|interpro:IPR022207|interpro:IPR042337 rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:demu8MwWIxvbEfrM+pBn3gDTUO09606 rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606 intact-crc:788D49065523BEDF|rigid:TlugEfoLJACm/9TuUAItQ27l0w4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BT88 uniprotkb:Q92624 intact:EBI-751770|uniprotkb:Q14998|uniprotkb:Q68CT5|uniprotkb:Q8IXU3|uniprotkb:Q96SU2|uniprotkb:Q5W0D4|ensembl:ENSP00000357307 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:syt11_human(display_long)|uniprotkb:Synaptotagmin XI(gene name synonym)|uniprotkb:SYT11(gene name)|psi-mi:SYT11(display_short)|uniprotkb:KIAA0080(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349987|imex:IM-20259-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689493.3|ensembl:ENSG00000132718(gene)|ensembl:ENST00000368324(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1900243"(negative regulation of synaptic vesicle endocytosis)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905154"(negative regulation of membrane invagination)|go:"GO:1905162"(regulation of phagosome maturation)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|go:"GO:1905469"(negative regulation of clathrin-coated pit assembly)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028699|interpro:IPR035892|reactome:R-HSA-8856825|reactome:R-HSA-8856828 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+unyxZC+Tuj9r8wtvicjY+Yig+I9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:6F24FE29D1288F70|rigid:mEIa+MwDNQ+ki1Sojl4tU/6VbGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q96D21 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-2349993|uniprotkb:Q5THY8|uniprotkb:O95520|ensembl:ENSP00000216127 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:rhes_human(display_long)|uniprotkb:RASD2(gene name)|psi-mi:RASD2(display_short)|uniprotkb:TEM2(gene name synonym)|uniprotkb:Ras homolog enriched in striatum(gene name synonym)|uniprotkb:Tumor endothelial marker 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2349991|imex:IM-20259-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:XP_011528342.1|refseq:NP_055125.2|refseq:XP_005261499.1|refseq:XP_016884190.1|refseq:XP_016884191.1|ensembl:ENSG00000100302(gene)|ensembl:ENST00000216127(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:gEU7RPbzdPERuaXm8i6CoRjmz/Q9606 intact-crc:F4556D78697CB94F|rigid:+SjGmP2vfhOhWqvrPs7XG0NBzSM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95865 uniprotkb:Q15645 intact:EBI-749139|uniprotkb:A2BEZ7|ensembl:ENSP00000364943|ensembl:ENSP00000364945|ensembl:ENSP00000364949|ensembl:ENSP00000372901|ensembl:ENSP00000382935|ensembl:ENSP00000389552|ensembl:ENSP00000391632|ensembl:ENSP00000391833|ensembl:ENSP00000395372|ensembl:ENSP00000395759|ensembl:ENSP00000397466|ensembl:ENSP00000399023|ensembl:ENSP00000399357|ensembl:ENSP00000402594|ensembl:ENSP00000403154|ensembl:ENSP00000404342|ensembl:ENSP00000404851|ensembl:ENSP00000405515|ensembl:ENSP00000408148|ensembl:ENSP00000409396|ensembl:ENSP00000412327|ensembl:ENSP00000412800|ensembl:ENSP00000382936 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ddah2_human(display_long)|uniprotkb:DDAHII(gene name synonym)|uniprotkb:Dimethylargininase-2(gene name synonym)|uniprotkb:S-phase protein(gene name synonym)|uniprotkb:Protein G6a(gene name synonym)|uniprotkb:DDAH2(gene name)|psi-mi:DDAH2(display_short)|uniprotkb:DDAH(gene name synonym)|uniprotkb:G6A(gene name synonym)|uniprotkb:NG30(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350001|imex:IM-20259-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206395(gene)|ensembl:ENSG00000213722(gene)|ensembl:ENSG00000225635(gene)|ensembl:ENSG00000226634(gene)|ensembl:ENSG00000227317(gene)|ensembl:ENSG00000228128(gene)|ensembl:ENSG00000233076(gene)|refseq:NP_039268.1|refseq:XP_011512750.1|refseq:NP_001289936.1|refseq:NP_001289937.1|ensembl:ENST00000375787(transcript)|ensembl:ENST00000375789(transcript)|ensembl:ENST00000375792(transcript)|ensembl:ENST00000383409(transcript)|ensembl:ENST00000437889(transcript)|ensembl:ENST00000400062(transcript)|ensembl:ENST00000400063(transcript)|ensembl:ENST00000411456(transcript)|ensembl:ENST00000413532(transcript)|ensembl:ENST00000413655(transcript)|ensembl:ENST00000414455(transcript)|ensembl:ENST00000416410(transcript)|ensembl:ENST00000443533(transcript)|ensembl:ENST00000424790(transcript)|ensembl:ENST00000426149(transcript)|ensembl:ENST00000444699(transcript)|ensembl:ENST00000447101(transcript)|ensembl:ENST00000451411(transcript)|ensembl:ENST00000454138(transcript)|ensembl:ENST00000427126(transcript)|go:"GO:0000052"(citrulline metabolic process)|ensembl:ENST00000430482(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005739"(mitochondrion)|ensembl:ENST00000434464(transcript)|ensembl:ENST00000436437(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016403"(dimethylargininase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR033199|interpro:IPR033202|reactome:R-HSA-203615|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:u/xau/wTFcLGsICADPBRLQWljkk9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:AFA4FABC4C812B87|rigid:4J3Vf3fPc2tGf0WaJCDCMlJcr4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q9UBV8 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-724639|ensembl:ENSP00000362807 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:pef1_human(display_long)|uniprotkb:PEF protein with a long N-terminal hydrophobic domain(gene name synonym)|uniprotkb:Penta-EF hand domain-containing protein 1(gene name synonym)|uniprotkb:PEF1(gene name)|psi-mi:PEF1(display_short)|uniprotkb:ABP32(gene name synonym)|uniprotkb:UNQ1845/PRO3573(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350005|imex:IM-20259-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_036524.1|ensembl:ENSG00000162517(gene)|ensembl:ENST00000373703(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0003723"(RNA binding)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBV8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:HoQa0GPucZdIv5g9+OoHdanlyPo9606 intact-crc:E59A56CDD118CDE3|rigid:vLKsKHujiO9uz8MaVQYWuh69/TQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95073 uniprotkb:O95073 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350014|imex:IM-20259-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 intact-crc:52D027683C708052|rigid:ZRn7LzQChXXs5PheOPxqgl6t+h0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6RW13 uniprotkb:Q9UKF7 intact:EBI-741181|ensembl:ENSP00000319713|uniprotkb:A8MVQ5|uniprotkb:Q5SNV4|uniprotkb:Q5SNV5|uniprotkb:Q96AC0|uniprotkb:Q96PL4|uniprotkb:Q9NRW9 intact:EBI-749241|uniprotkb:Q96I07|uniprotkb:A8K473|uniprotkb:J3QR20|ensembl:ENSP00000464006 psi-mi:atrap_human(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:ATRAP(gene name synonym) psi-mi:pitc1_human(display_long)|uniprotkb:Retinal degeneration B homolog beta(gene name synonym)|uniprotkb:Mammalian rdgB homolog beta(gene name synonym)|uniprotkb:PITPNC1(gene name)|psi-mi:PITPNC1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350018|imex:IM-20259-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035284.1|refseq:NP_001035285.1|refseq:NP_001035286.1|refseq:NP_001035287.1|refseq:NP_065083.3|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:Q6RW13|reactome:R-HSA-6802952|ensembl:ENSG00000177674(gene)|ensembl:ENST00000314340(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus) refseq:NP_858057.1|refseq:NP_036549.2|ensembl:ENSG00000154217(gene)|ensembl:ENST00000581322(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901611"(phosphatidylglycerol binding)|go:"GO:1990050"(phosphatidic acid transfer activity)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR023393 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:z+Us8VGLb+tlxNibfVodbuMZ6+89606 rogid:wN3p8shBXRlygSywNjvBMcVNmq89606 intact-crc:AFBEB539BC05F769|rigid:9Zg3QyAVwJxO4sz3TWCtOFF4nn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y247 uniprotkb:O95751 intact:EBI-742802|uniprotkb:Q5T2L6|ensembl:ENSP00000369627|ensembl:ENSP00000496837 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:fa50b_human(display_long)|uniprotkb:Protein XAP-5-like(gene name synonym)|uniprotkb:FAM50B(gene name)|psi-mi:FAM50B(display_short)|uniprotkb:X5L(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350022|imex:IM-20259-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036267.1|ensembl:ENST00000380274(transcript)|ensembl:ENST00000648326(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030496"(midbody)|go:"GO:0045171"(intercellular bridge)|interpro:IPR007005(XAP5 protein)|mint:Q9Y247|ensembl:ENSG00000145945(gene)|refseq:XP_016866218.1 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+GYwKGuchxbVElEibszICsOAgFo9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:B4DF78CE03C29736|rigid:khXRxvo6bloVRAWhvxZxU2f7OLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q8NE01 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-741032|ensembl:ENSP00000305449|uniprotkb:Q8TBV4|uniprotkb:Q96IW4|uniprotkb:Q9NRK4|uniprotkb:Q9NXW6|uniprotkb:B3KX67 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cnnm3_human(display_long)|uniprotkb:Cyclin-M3(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 3(gene name synonym)|uniprotkb:CNNM3(gene name)|psi-mi:CNNM3(display_short)|uniprotkb:ACDP3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350026|imex:IM-20259-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_060093.3|refseq:NP_951060.1|ensembl:ENSG00000168763(gene)|ensembl:ENST00000305510(transcript)|go:"GO:0006811"(ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR044751|mint:Q8NE01|rcsb pdb:5K22|rcsb pdb:5K23|rcsb pdb:5K25|rcsb pdb:5TSR|rcsb pdb:6DFD|rcsb pdb:6MN6|rcsb pdb:6WUR|go:"GO:0005886"(plasma membrane) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:AHuatMC/j3lteiKZli8vu5ZM6vk9606 intact-crc:996452C0E8CA4754|rigid:ZWSDWU1KDmiT9YfWRJ53eM0FuLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P55040 uniprotkb:P36406 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350030|imex:IM-20259-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:8733048892E2A090|rigid:o/NjexZaxcAomAiDcIkgcNrkduI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GA7 uniprotkb:Q9UGJ1 intact:EBI-744440|ensembl:ENSP00000341117|ensembl:ENSP00000385790 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:sdsl_human(display_long)|uniprotkb:Serine dehydratase 2(gene name synonym)|uniprotkb:SDSL(gene name)|psi-mi:SDSL(display_short)|uniprotkb:L-serine deaminase(gene name synonym)|uniprotkb:L-threonine dehydratase(gene name synonym)|uniprotkb:L-serine dehydratase/L-threonine deaminase(gene name synonym) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350034|imex:IM-20259-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612441.1|refseq:NP_001291922.1|refseq:XP_011536148.1|refseq:XP_005253888.1|ensembl:ENSG00000139410(gene)|ensembl:ENST00000345635(transcript)|ensembl:ENST00000403593(transcript)|go:"GO:0003941"(L-serine ammonia-lyase activity)|go:"GO:0004794"(L-threonine ammonia-lyase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006567"(threonine catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000634(Serine/threonine dehydratase, pyridoxal-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR036052|rcsb pdb:2RKB|reactome:R-HSA-8849175 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:h/KXL0QQIvUmSrpZt/Kgg41l5Ck9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:1311AB05828FE9B6|rigid:SQMqY81w3rdq0D+8phHUxZgbvFQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UGJ1 uniprotkb:Q9UKJ5 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-741528|ensembl:ENSP00000263921|uniprotkb:B2R639 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:chic2_human(display_long)|uniprotkb:BrX-like translocated in leukemia(gene name synonym)|uniprotkb:CHIC2(gene name)|psi-mi:CHIC2(display_short)|uniprotkb:BTL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350038|imex:IM-20259-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_036242.1|ensembl:ENSG00000109220(gene)|ensembl:ENST00000263921(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019383|interpro:IPR039735 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:pdPnbCymmDTe6+o8PTDcQT595nY9606 intact-crc:DECA619B09770C2F|rigid:YZwdDhPx/G5Ss+E7e6BmDUJbrfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6UY14 uniprotkb:Q9UGJ1 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350042|imex:IM-20259-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:79B55FE66A45E8C0|rigid:A9hA5jCjRGqJIQFK006AbrRL8Ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UGJ1 uniprotkb:P14373 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350046|imex:IM-20259-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 intact-crc:608F859FF674CBFB|rigid:XYzcFJ1DVvTfVHhZ1f59rBOKe4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5JST6 uniprotkb:Q9UGJ1 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350050|imex:IM-20259-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:D2385DB0502E9080|rigid:ym92aHkXmiMjbfWyumi6odbnOdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N653 uniprotkb:Q9UGJ1 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350054|imex:IM-20259-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:1936A7E8D405D88A|rigid:zmcpscywWaynm9yCntg03mKuTLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UGJ1 uniprotkb:Q8TES7 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-2350063|uniprotkb:B5MEM5|uniprotkb:Q96IF6|uniprotkb:Q96MA8|uniprotkb:Q96JG4|ensembl:ENSP00000465132 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:fbf1_human(display_long)|uniprotkb:ALB(gene name synonym)|uniprotkb:Protein albatross(gene name synonym)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)|uniprotkb:KIAA1863(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350071|imex:IM-20259-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_001306122.1|ensembl:ENSG00000188878(gene)|ensembl:ENST00000586717(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043297"(apical junction assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|reactome:R-HSA-5620912 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:L3WrrMbCU9aCdYlXB4h9s/WVU2o9606 intact-crc:E779D36F54B575BB|rigid:spo3BY6305IR7WYf/SlQ3PLOq/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62310 uniprotkb:Q969L4 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 intact:EBI-373268|ensembl:ENSP00000319341 psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:lsm10_human(display_long)|uniprotkb:LSM10(gene name)|psi-mi:LSM10(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350075|imex:IM-20259-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N refseq:NP_116270.1|ensembl:ENSG00000181817(gene)|ensembl:ENST00000315732(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005683"(U7 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:6V4X|reactome:R-HSA-111367|reactome:R-HSA-73856|reactome:R-HSA-77588 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rogid:4ppK2+oa0v/jsg0A8/cbgcZs2g49606 intact-crc:EFDFFE55DC27CD7D|rigid:ruHwUQ9sQlULEh9OjA7OlADQB24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92624 uniprotkb:P14770 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350083|imex:IM-20259-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606 intact-crc:C3C68FDD23631865|rigid:lIKQPQMsqiNXGxJTN/FWgXCoVO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96M61 uniprotkb:Q06547 intact:EBI-741835|ensembl:ENSP00000314543 intact:EBI-618165|ensembl:ENSP00000220429|uniprotkb:Q06545|uniprotkb:Q12940|uniprotkb:Q12941|uniprotkb:Q12942|uniprotkb:Q8IYD0|uniprotkb:A8IE52 psi-mi:magbi_human(display_long)|uniprotkb:MAGE-B18 antigen(gene name synonym)|uniprotkb:MAGEB18(gene name)|psi-mi:MAGEB18(display_short) psi-mi:gabp1_human(display_long)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350087|imex:IM-20259-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775970.1|ensembl:ENSG00000176774(gene)|ensembl:ENST00000325250(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|ensembl:ENSP00000314543 ensembl:ENSG00000104064(gene)|ensembl:ENST00000220429(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q06547|reactome:R-HSA-2151201|refseq:NP_002032.2|refseq:NP_005245.2|refseq:NP_057738.1|refseq:NP_057739.1|refseq:NP_852092.1|refseq:NP_001307839.1|refseq:XP_005254331.1|refseq:XP_016877542.1|dip:DIP-33979N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:eiI365GXPz0jCpm8/Oc1QscEDD09606 rogid:JO5HOl2ohh7LmNIn5UyYNbGviYE9606 intact-crc:7EF6BED877624171|rigid:xaCiANXO6WsWK8NbUpNvY1L3RJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0W9 uniprotkb:Q15645 intact:EBI-740204|uniprotkb:Q6FI88|uniprotkb:Q6XYB0|uniprotkb:Q96EI3|uniprotkb:Q96IX1|uniprotkb:Q9Y6B4|ensembl:ENSP00000346403|ensembl:ENSP00000435113|ensembl:ENSP00000331209|uniprotkb:A8K850 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ck054_human(display_long)|uniprotkb:C11orf54(gene name)|psi-mi:C11orf54(display_short)|uniprotkb:LP4947(orf name)|uniprotkb:PTD012(orf name) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350091|imex:IM-20259-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272996.1|refseq:NP_001272997.1|refseq:NP_001272998.1|refseq:NP_001272999.1|refseq:NP_001273000.1|refseq:NP_054758.2|ensembl:ENST00000331239(transcript)|ensembl:ENST00000354421(transcript)|ensembl:ENST00000528099(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015021(Region of unknown function DUF1907)|rcsb pdb:1XCR|ensembl:ENSG00000182919(gene)|refseq:XP_016873105.1|refseq:XP_011541083.1|refseq:XP_011541084.1|refseq:XP_006718887.1|refseq:XP_016873102.1|refseq:XP_016873103.1|refseq:XP_016873104.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+tNv81xp+nSoxhIbvT5MAYrZ+FY9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:60962031C0D705DD|rigid:3W+o68y9SFFYLhr3CWi3rOvXbjU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21266 uniprotkb:P21266 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350095|imex:IM-20259-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249 refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 intact-crc:FFDC5534505741C4|rigid:EqAux5AHNCr/MkVeOk9dZRdDRpM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21673 uniprotkb:P17482 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350107|imex:IM-20259-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:F371B0659FEE3211|rigid:BXElRzW3BNfp72dUfMMig/8g2ds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:P17482 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350103|imex:IM-20259-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:2665B2B562B81D42|rigid:ffBFWN4bPe4MINWhvDXOfHqP/24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15654 uniprotkb:P31269 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-742314|uniprotkb:O43369|uniprotkb:O43429|uniprotkb:Q99820|ensembl:ENSP00000343619 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:hxa9_human(display_long)|uniprotkb:HOXA9(gene name)|psi-mi:HOXA9(display_short)|uniprotkb:HOX1G(gene name synonym)|uniprotkb:Homeobox protein Hox-1G(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350099|imex:IM-20259-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_689952.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSG00000078399(gene)|ensembl:ENST00000343483(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:04nr6zxW4HQtzJhTZNTajO6jmWY9606 intact-crc:0A630CF30AFC607B|rigid:fv04ItSTaBaZaR+mRyswcg0ME0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29972 uniprotkb:Q6UY14 intact:EBI-745213|uniprotkb:Q8TBI5|uniprotkb:Q8TDC1|uniprotkb:B5BU39|ensembl:ENSP00000311165|ensembl:ENSP00000498672|uniprotkb:F5GY19|uniprotkb:E7EM69|uniprotkb:E9PC21 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 psi-mi:aqp1_human(display_long)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)|uniprotkb:Urine water channel(gene name synonym)|uniprotkb:AQP1(gene name)|psi-mi:AQP1(display_short)|uniprotkb:CHIP28(gene name synonym) psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350115|imex:IM-20259-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932766.1|ensembl:ENSG00000240583(gene)|ensembl:ENST00000311813(transcript)|ensembl:ENST00000652696(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|rcsb pdb:1FQY|rcsb pdb:1H6I|rcsb pdb:1IH5|rcsb pdb:4CSK|rcsb pdb:6POJ|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-29607N refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:0y0L/lmXZ68WhUSetgKRrSFdT1I9606 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 intact-crc:A2E667E623889488|rigid:CZmv83gz6s+SRn3zGrw0gf/8qcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29972 uniprotkb:Q99750 intact:EBI-745213|uniprotkb:Q8TBI5|uniprotkb:Q8TDC1|uniprotkb:B5BU39|ensembl:ENSP00000311165|ensembl:ENSP00000498672|uniprotkb:F5GY19|uniprotkb:E7EM69|uniprotkb:E9PC21 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:aqp1_human(display_long)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)|uniprotkb:Urine water channel(gene name synonym)|uniprotkb:AQP1(gene name)|psi-mi:AQP1(display_short)|uniprotkb:CHIP28(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350111|imex:IM-20259-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932766.1|ensembl:ENSG00000240583(gene)|ensembl:ENST00000311813(transcript)|ensembl:ENST00000652696(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|rcsb pdb:1FQY|rcsb pdb:1H6I|rcsb pdb:1IH5|rcsb pdb:4CSK|rcsb pdb:6POJ|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-29607N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:0y0L/lmXZ68WhUSetgKRrSFdT1I9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:AFD95733F75C11BE|rigid:vSDDKcLShwOLPH57V3bHjjpggBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06547 uniprotkb:Q8IUU6 intact:EBI-618165|ensembl:ENSP00000220429|uniprotkb:Q06545|uniprotkb:Q12940|uniprotkb:Q12941|uniprotkb:Q12942|uniprotkb:Q8IYD0|uniprotkb:A8IE52 intact:EBI-746574 psi-mi:gabp1_human(display_long)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym) psi-mi:q8iuu6_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350119|imex:IM-20259-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104064(gene)|ensembl:ENST00000220429(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q06547|reactome:R-HSA-2151201|refseq:NP_002032.2|refseq:NP_005245.2|refseq:NP_057738.1|refseq:NP_057739.1|refseq:NP_852092.1|refseq:NP_001307839.1|refseq:XP_005254331.1|refseq:XP_016877542.1|dip:DIP-33979N interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JO5HOl2ohh7LmNIn5UyYNbGviYE9606 rogid:6UMK2pY5ytVRxzocsv5L27L5Y4c9606 intact-crc:54856A0EC58B964B|rigid:LpZ8VWoRMbp4gz+b4bvCQZOnaaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IUU6 uniprotkb:Q96MA1 intact:EBI-746574 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 psi-mi:q8iuu6_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short) psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350123|imex:IM-20259-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6UMK2pY5ytVRxzocsv5L27L5Y4c9606 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 intact-crc:99819A5F36E2911C|rigid:5IvcDAKH8O6rBYV4GLgSK8j+ZVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q14847 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350131|imex:IM-20259-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 intact-crc:F955B8C30EE76ABA|rigid:d8D3aBEKwZ1TL+zzUdxmUZWdEbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:P55064 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-746103|uniprotkb:Q6FGW8|ensembl:ENSP00000293599 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:aqp5_human(display_long)|uniprotkb:AQP5(gene name)|psi-mi:AQP5(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350127|imex:IM-20259-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001642.1|ensembl:ENSG00000161798(gene)|ensembl:ENST00000293599(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0005902"(microvillus)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046541"(saliva secretion)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023276|interpro:IPR034294|rcsb pdb:3D9S|rcsb pdb:5C5X|rcsb pdb:5DYE|reactome:R-HSA-432047|dip:DIP-46292N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:YqO+Y0prbff02iGeHMUow4FcIRc9606 intact-crc:1C8A8C9952BE9F9B|rigid:sf998/lrdGdrE50CNHfwLSSGoy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14847 uniprotkb:Q15645 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350135|imex:IM-20259-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:0FD118F215A51DEA|rigid:EH2HGAakeh0Gq1uo0pBpitqiOBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14847 uniprotkb:Q15038 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350139|imex:IM-20259-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:619CE365B360DA03|rigid:qbODRqJs9/9admDJ+dPblBLCqis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:P48059 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350143|imex:IM-20259-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606 intact-crc:368350DF630ADC73|rigid:IxRG/E4n4boa5Ukk1otVm1yV6ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75427 uniprotkb:Q99750 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350147|imex:IM-20259-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:193B5F23B7874700|rigid:iCvWrkm+sYPB2PzGi5PtkGzkXfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q5T681 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744052|uniprotkb:Q49A70|uniprotkb:Q8N3Y6|ensembl:ENSP00000359674 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cj062_human(display_long)|uniprotkb:C10orf62(gene name)|psi-mi:C10orf62(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350151|imex:IM-20259-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001009997.2|ensembl:ENSG00000203942(gene)|ensembl:ENST00000370640(transcript)|interpro:IPR037649 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:UL8jisC+5EfnT+1B4SyTXUxQVlg9606 intact-crc:7CE9A208D193C603|rigid:kc/rtqDyAUBaZiidWEY+qSttrCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40692 uniprotkb:O75152 intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym) psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350155|imex:IM-20259-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446 refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 intact-crc:2530AEDF669964F1|rigid:QrpbSGZh99Bq1o25P7i8VZbnC9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:O95182 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350159|imex:IM-20259-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 intact-crc:59684BE3F030108E|rigid:RfabJbdTP6p2PKdqSn6NukEDiOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60260 uniprotkb:Q15645 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350167|imex:IM-20259-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:87BF8D90AF9743DA|rigid:xOYs9y00A8MghVFchHCvMKpXo3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23511 uniprotkb:Q92624 intact:EBI-389739|uniprotkb:Q8IXU0|ensembl:ENSP00000345702 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:nfya_human(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350163|imex:IM-20259-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002496.1|refseq:NP_068351.1|ensembl:ENSG00000001167(gene)|ensembl:ENST00000341376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B)|interpro:IPR018362|rcsb pdb:4AWL|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ZzEyS17rD3653YFSvnBoGdl1T3s9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:5803D948A475CBE6|rigid:CxR3VDsOVUNAPPKD+VV8vOzQdPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q96AL5 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-741171 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:q96al5_human(display_long)|uniprotkb:PBX3(gene name)|psi-mi:PBX3(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350175|imex:IM-20259-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR005542(PBX)|refseq:NP_006186.1|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:i9wU2k+DRdIptKLg9/LACfQiX0o9606 intact-crc:0BC5C78CFA3BF062|rigid:+6puSmjjKvWYnyieh8VEcG1n7y8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TAQ9 uniprotkb:Q99750 intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350171|imex:IM-20259-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:CF04E7F7DD6C4EE6|rigid:4qmRZmk/qTtWc690EgBo7TdJphY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6RW13 uniprotkb:Q96AL5 intact:EBI-741181|ensembl:ENSP00000319713|uniprotkb:A8MVQ5|uniprotkb:Q5SNV4|uniprotkb:Q5SNV5|uniprotkb:Q96AC0|uniprotkb:Q96PL4|uniprotkb:Q9NRW9 intact:EBI-741171 psi-mi:atrap_human(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:ATRAP(gene name synonym) psi-mi:q96al5_human(display_long)|uniprotkb:PBX3(gene name)|psi-mi:PBX3(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350179|imex:IM-20259-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035284.1|refseq:NP_001035285.1|refseq:NP_001035286.1|refseq:NP_001035287.1|refseq:NP_065083.3|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:Q6RW13|reactome:R-HSA-6802952|ensembl:ENSG00000177674(gene)|ensembl:ENST00000314340(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus) interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR005542(PBX)|refseq:NP_006186.1|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:z+Us8VGLb+tlxNibfVodbuMZ6+89606 rogid:i9wU2k+DRdIptKLg9/LACfQiX0o9606 intact-crc:5A0F98631F3A60D8|rigid:RDCkNbJkG5spSCngbCRlRetTZPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3B2 uniprotkb:Q9NQT4 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350183|imex:IM-20259-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 intact-crc:B489FAE57131C13A|rigid:g4l1Xa47ej5OzCFmRa1UR7MkUek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GX9 uniprotkb:Q96GX9 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350187|imex:IM-20259-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 intact-crc:A47C069D2CB508CD|rigid:a/+LJWdWTbqNg0idZjWaJeeBVac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99816 uniprotkb:Q9UK41 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350191|imex:IM-20259-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:D292AC9CB62A1FCC|rigid:IPcqleypZ+xH6ZjayAZoSPsWZ4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P2T0 uniprotkb:Q99750 intact:EBI-751020|uniprotkb:A6NMJ8|ensembl:ENSP00000340088 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:theg_human(display_long)|uniprotkb:Cancer/testis antigen 56(gene name synonym)|uniprotkb:THEG(gene name)|psi-mi:THEG(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350195|imex:IM-20259-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057669.1|refseq:NP_954672.1|ensembl:ENSG00000105549(gene)|ensembl:ENST00000342640(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR006623(Testicular haploid expressed repeat)|interpro:IPR042401 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PZ1WgUhnuF1kU16FsiZlJwqS8QE9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:7551CBD642FF35B0|rigid:rQZUrWfgUaLM98r8oIbpecknzvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01127 uniprotkb:Q99750 intact:EBI-1554925|uniprotkb:P78431|uniprotkb:Q9UF23|uniprotkb:G3XAG8|uniprotkb:Q15354|uniprotkb:Q6FHE7|ensembl:ENSP00000330382 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pdgfb_human(display_long)|uniprotkb:Platelet-derived growth factor B chain(gene name synonym)|uniprotkb:Platelet-derived growth factor beta polypeptide(gene name synonym)|uniprotkb:PDGF-2(gene name synonym)|uniprotkb:Proto-oncogene c-Sis(gene name synonym)|uniprotkb:PDGFB(gene name)|psi-mi:PDGFB(display_short)|uniprotkb:PDGF2(gene name synonym)|uniprotkb:SIS(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350203|imex:IM-20259-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002599.1|refseq:NP_148937.1|dip:DIP-5737N|ensembl:ENSG00000100311(gene)|ensembl:ENST00000331163(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035793"(positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071506"(cellular response to mycophenolic acid)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072255"(metanephric glomerular mesangial cell development)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905176"(positive regulation of vascular associated smooth muscle cell dedifferentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000591"(positive regulation of metanephric mesenchymal cell migration)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR006782(Platelet-derived growth factor, N-terminal)|interpro:IPR015583(Platelet-Derived Growth Factor B Chain)|interpro:IPR023581|interpro:IPR029034|rcsb pdb:1PDG|rcsb pdb:3MJG|rcsb pdb:4HQU|rcsb pdb:4HQX|rcsb pdb:4QCI|rcsb pdb:6T9E|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-186763|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-3000171|reactome:R-HSA-5673001|reactome:R-HSA-6811558 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6zBbnXOTaM6thsuAbXfQoHHZ/EA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:E598BFF1E69ACD9E|rigid:LonZa4T01KXnCHi/KMiR3Thdn5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13049 uniprotkb:O76083 intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8 intact:EBI-742764|uniprotkb:O75490|uniprotkb:O75491|uniprotkb:O95225|uniprotkb:Q86SF7|uniprotkb:Q86SI6|uniprotkb:Q86SJ3|uniprotkb:Q86WN3|uniprotkb:Q86WN4|uniprotkb:Q86WN5|uniprotkb:Q86WN6|uniprotkb:Q86WN7|uniprotkb:Q86WN8|uniprotkb:Q86WN9|uniprotkb:Q86WP0|uniprotkb:B2RBI5|uniprotkb:Q53Y40|uniprotkb:B4DFI5|uniprotkb:Q5QD39|uniprotkb:D3DSJ8|uniprotkb:D3DSJ9|ensembl:ENSP00000291539 psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym) psi-mi:pde9a_human(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350199|imex:IM-20259-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1 rcsb pdb:3DYS|refseq:NP_001001567.1|refseq:NP_001001568.1|refseq:NP_001001569.1|refseq:NP_001001570.1|refseq:NP_001001571.1|refseq:NP_001001572.1|refseq:NP_001001573.1|refseq:NP_001001574.1|refseq:NP_001001575.1|refseq:NP_001001576.1|refseq:NP_001001577.1|refseq:NP_001001578.1|refseq:NP_001001579.1|refseq:NP_001001580.1|refseq:NP_001001581.1|refseq:NP_001001582.1|refseq:NP_001001583.1|refseq:NP_001001584.1|refseq:NP_001001585.1|refseq:NP_002597.1|refseq:NP_001302462.1|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0046068"(cGMP metabolic process)|go:"GO:0046069"(cGMP catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047555"(3',5'-cyclic-GMP phosphodiesterase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|ensembl:ENSG00000160191(gene)|ensembl:ENST00000291539(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0032587"(ruffle membrane)|interpro:IPR023174|interpro:IPR036971|mint:O76083|rcsb pdb:2HD1|rcsb pdb:2YY2|rcsb pdb:3DY8|rcsb pdb:3DYL|rcsb pdb:3DYN|rcsb pdb:3DYQ|rcsb pdb:3JSW|rcsb pdb:3K3E|rcsb pdb:3K3H|rcsb pdb:3N3Z|rcsb pdb:3QI3|rcsb pdb:3QI4|rcsb pdb:4E90|rcsb pdb:4G2J|rcsb pdb:4G2L|rcsb pdb:4GH6|rcsb pdb:4Y86|rcsb pdb:4Y87|rcsb pdb:4Y8C|rcsb pdb:6A3N|rcsb pdb:6LZZ|reactome:R-HSA-418457|rcsb pdb:3JSI|refseq:XP_016883855.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606 rogid:ihS9g9TSkHsEA4olMOO+krgypow9606 intact-crc:3089C414746F8A29|rigid:POOKDODWO1M5AqOfEbR3K/PjifU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:Q9NS73 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350207|imex:IM-20259-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:3F2E1ACFCF0BA216|rigid:FnF/rpb5E9sPkpqXuWSdD0GfNts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UH62 uniprotkb:Q9H063 intact:EBI-717832|uniprotkb:Q53HC6|uniprotkb:Q7LCF5|uniprotkb:Q9NPE4|ensembl:ENSP00000340672|ensembl:ENSP00000439032|ensembl:ENSP00000454483 intact:EBI-720354|uniprotkb:D3DWL4|ensembl:ENSP00000318604|ensembl:ENSP00000436720 psi-mi:armx3_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 3(gene name synonym)|uniprotkb:ARMCX3(gene name)|psi-mi:ARMCX3(display_short)|uniprotkb:ALEX3(gene name synonym)|uniprotkb:BM-017(orf name)|uniprotkb:UNQ2517/PRO6007(orf name) psi-mi:maf1_human(display_long)|uniprotkb:MAF1(gene name)|psi-mi:MAF1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350211|imex:IM-20259-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057691.1|refseq:NP_808816.1|refseq:NP_808817.1|refseq:XP_005262198.1|ensembl:ENSG00000102401(gene)|ensembl:ENST00000341189(transcript)|ensembl:ENST00000471229(transcript)|ensembl:ENST00000537169(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-9013404 refseq:NP_115648.2|ensembl:ENST00000532522(transcript)|go:"GO:0000994"(RNA polymerase III core binding)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENST00000322428(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR015257(Maf1 regulator)|interpro:IPR038564|rcsb pdb:3NR5|reactome:R-HSA-8943724|go:"GO:0050811"(GABA receptor binding)|ensembl:ENSG00000179632(gene)|refseq:XP_016869393.1|dip:DIP-53028N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Svmu819cxCJThLvYapRMLQpAszw9606 rogid:oendhtb8R+yuFDCrOhSxk8kRrVI9606 intact-crc:79E611F4F28DE6A4|rigid:kLXrsxbsJYKbAS6v4T+kKqWqVZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0E2 uniprotkb:Q15038 intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350215|imex:IM-20259-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:264175680ABB76FE|rigid:i5423jFYW5U/NCFw8dk2iIoSCqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17028 uniprotkb:Q9NX65 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350219|imex:IM-20259-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 intact-crc:8DD9F86C8E3D4D3A|rigid:sGZOJJc3ZY+v6INXgeeRr04caGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q8N9H8 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-750745|uniprotkb:Q6P1M1|uniprotkb:Q8IXT8|uniprotkb:A0A140VJP9|uniprotkb:B8A4U7|uniprotkb:C9JIQ9|uniprotkb:E9PN82|uniprotkb:Q2TAK4|uniprotkb:Q8N3X4|uniprotkb:Q8NHD1|uniprotkb:Q96NP1|uniprotkb:Q9NX53|ensembl:ENSP00000340474 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:mut7_human(display_long)|uniprotkb:EXD3(gene name)|psi-mi:EXD3(display_short)|uniprotkb:Exonuclease 3'-5' domain-containing protein 3(gene name synonym)|uniprotkb:HBE269(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350223|imex:IM-20259-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_001273752.1|refseq:NP_060290.3|ensembl:ENSG00000187609(gene)|ensembl:ENST00000340951(transcript)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR002782(Protein of unknown function DUF82)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR037432|go:"GO:0003676"(nucleic acid binding) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:uBnG+EqGieSQ9G+7oh0Kdd2QuLU9606 intact-crc:71707BA7F4E57ADF|rigid:nG3g4cRL91/Noqxdq2ngnC/U3bQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q96HA8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350231|imex:IM-20259-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:8BB36B85147552C2|rigid:gxrpq7UZ4gIw1dABQ/QFkJg7Oq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96EN9 uniprotkb:Q99750 intact:EBI-745810|uniprotkb:Q8NAX4|uniprotkb:Q9NWI0|ensembl:ENSP00000351422|intact:EBI-11084128|uniprotkb:E9PAS0 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:rex1b_human(display_long)|uniprotkb:REX1BD(gene name)|psi-mi:REX1BD(display_short)|uniprotkb:C19orf60(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350227|imex:IM-20259-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093888.1|refseq:NP_001093889.1|ensembl:ENSG00000006015(gene)|ensembl:ENST00000358607(transcript)|interpro:IPR039491 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:y/YOKlXvG7PSR+fFGaenSTvgxO09606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:31B58CAB6EB23B49|rigid:nEJ8Ijo2sNDKyEl3fB6Z/0+G738 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00492 uniprotkb:Q96HA8 intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350235|imex:IM-20259-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:AAC209CC65EE9119|rigid:mWUnpuF9r51/wArignTkCnp79rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14923 uniprotkb:Q96HA8 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350239|imex:IM-20259-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:BC4B97DDB098CDDF|rigid:o1qFsMUgaiSCI5pYfmRD/TMEANQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HA8 uniprotkb:P15531 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350243|imex:IM-20259-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:876109AC1079B917|rigid:Ev6J3CH9sB+ovO4ubnpabzQfqh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HA8 uniprotkb:Q9BPX1 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350247|imex:IM-20259-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 intact-crc:849B9FD2D47A0020|rigid:JLkgRQATLmyge3rE6mGX/uMIImc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03393 uniprotkb:Q96HA8 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350251|imex:IM-20259-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:674C72D50AE5AD02|rigid:yXNtuzKAjjfLVUe/OT6kGh7zw6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P67775 uniprotkb:Q15645 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350259|imex:IM-20259-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:D4ACBB58D9F72E3C|rigid:dQ41Om7CQlVlLMmXSMZbK2qeBxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HA8 uniprotkb:Q15645 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350255|imex:IM-20259-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:CE25CAB130A1C600|rigid:C9dMo4hA1Eu0byyoMhDgGXs7QBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7L2Z9 uniprotkb:Q0VDD7 intact:EBI-2350265|uniprotkb:Q6IN61|uniprotkb:Q9NVS5|uniprotkb:A8KAF1|ensembl:ENSP00000337289 intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49 psi-mi:cenpq_human(display_long)|uniprotkb:CENPQ(gene name)|psi-mi:CENPQ(display_short)|uniprotkb:C6orf139(gene name synonym) psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350263|imex:IM-20259-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060602.2|refseq:XP_005249262.1|ensembl:ENSG00000031691(gene)|ensembl:ENST00000335783(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051310"(metaphase plate congression)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR025212|mint:Q7L2Z9|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:qSVZT9uWH/55f1YtdJrC7U90clk9606 rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606 intact-crc:CFDFEC52B0B57F2B|rigid:B/qAaYkItuYS9mp8RbLpuHRXvwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:Q9C0A6 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-745351|uniprotkb:Q6AI17|uniprotkb:Q8WUB6|uniprotkb:Q9H3X4|uniprotkb:Q9H6V7|uniprotkb:Q9H7S3|uniprotkb:Q9NVI9|ensembl:ENSP00000383939|ensembl:ENSP00000385852 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:setd5_human(display_long)|uniprotkb:SETD5(gene name)|psi-mi:SETD5(display_short)|uniprotkb:KIAA1757(gene name synonym)|uniprotkb:SET domain-containing protein 5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350274|imex:IM-20259-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_001073986.1|ensembl:ENSG00000168137(gene)|ensembl:ENST00000402198(transcript)|ensembl:ENST00000406341(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0050890"(cognition)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR001214(SET)|interpro:IPR044433|ensembl:ENSP00000385852|ensembl:ENSP00000383939|refseq:NP_001278972.1|refseq:XP_016862270.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:kuNqd2aC46saPlIZrVY0+CIJsRg9606 intact-crc:44DA64D4A2D8E146|rigid:e0NAYJSG643wR9dT7zF3LhCujk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVF9 uniprotkb:Q99750 intact:EBI-751864|uniprotkb:B7Z7K1|uniprotkb:Q5SXX5|uniprotkb:Q68CK3|uniprotkb:Q96G05|ensembl:ENSP00000356170 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:eki2_human(display_long)|uniprotkb:ETNK2(gene name)|psi-mi:ETNK2(display_short)|uniprotkb:EKI2(gene name synonym)|uniprotkb:Ethanolamine kinase-like protein(gene name synonym)|uniprotkb:HMFT1716(orf name) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350278|imex:IM-20259-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060678.2|refseq:NP_001284689.1|refseq:NP_001284690.1|refseq:NP_001284691.1|ensembl:ENSG00000143845(gene)|ensembl:ENST00000367202(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0035264"(multicellular organism growth)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-1483213 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:aZ+GrsqSpVjuyjNe6KyQA6h5QEg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:1CAE83D1CC341338|rigid:vu3tj2FwY0wTOY202ZcvlhEy6c4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95273 uniprotkb:Q9NV31 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-747481|uniprotkb:Q53G10|uniprotkb:B3KQ67|ensembl:ENSP00000326981|ensembl:ENSP00000385217 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:imp3_human(display_long)|uniprotkb:BRMS2(gene name synonym)|uniprotkb:IMP3(gene name)|psi-mi:IMP3(display_short)|uniprotkb:C15orf12(gene name synonym)|uniprotkb:MRPS4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350282|imex:IM-20259-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 refseq:NP_060755.1|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR022801|interpro:IPR036986|mint:Q9NV31|rcsb pdb:2CQJ|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0030515"(snoRNA binding)|ensembl:ENSG00000177971(gene)|ensembl:ENST00000314852(transcript)|ensembl:ENST00000403490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:7tf5HEal59lCqBIvQaFLksqchAw9606 intact-crc:CFCF8106534779AC|rigid:JjgrElmuTVWdN0QS9WxvN+kA5kE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HB75 uniprotkb:Q99750 intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350286|imex:IM-20259-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:B07D45B2133270D2|rigid:jKZl4jOHrhZ+DDgx4ybpOoaGBfg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKK6 uniprotkb:Q9H4D5 intact:EBI-301889|ensembl:ENSP00000254998 intact:EBI-750038|uniprotkb:Q9H1A9|uniprotkb:B4DYS7|uniprotkb:Q5H9I1|ensembl:ENSP00000378504 psi-mi:nxt1_human(display_long)|uniprotkb:NXT1(gene name)|psi-mi:NXT1(display_short)|uniprotkb:Protein p15(gene name synonym) psi-mi:nxf3_human(display_long)|uniprotkb:TAP-like protein 3(gene name synonym)|uniprotkb:NXF3(gene name)|psi-mi:NXF3(display_short)|uniprotkb:TAPL3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350290|imex:IM-20259-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132661(gene)|ensembl:ENST00000254998(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031267"(small GTPase binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|mint:Q9UKK6|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159236|refseq:NP_037380.1|refseq:XP_011527532.1|dip:DIP-33075N refseq:NP_071335.1|ensembl:ENSG00000147206(gene)|ensembl:ENST00000395065(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042272"(nuclear RNA export factor complex)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030216|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9H4D5 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PDP0uZzdRV3AfYiKREIBMCI1MBU9606 rogid:v0ff9hsaVYCa15gHW2PGhUDA8zY9606 intact-crc:65CE8D2AC9E79C33|rigid:I1CSQbcXfXxw7n+7l/sGP2JhgJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45984 uniprotkb:P32121 intact:EBI-713568|uniprotkb:Q15708|uniprotkb:Q15710|uniprotkb:Q15711|uniprotkb:Q8N5C5|uniprotkb:A8K0S3|ensembl:ENSP00000394560|uniprotkb:B5M0B4|uniprotkb:B5BU66|uniprotkb:D3DWQ8|uniprotkb:D3DWQ9 intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|ensembl:ENSP00000269260|uniprotkb:B4DLW0|uniprotkb:H0Y688 psi-mi:mk09_human(display_long)|uniprotkb:Stress-activated protein kinase JNK2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 2(gene name synonym)|uniprotkb:JNK-55(gene name synonym)|uniprotkb:MAPK9(gene name)|psi-mi:MAPK9(display_short)|uniprotkb:JNK2(gene name synonym)|uniprotkb:PRKM9(gene name synonym)|uniprotkb:Stress-activated protein kinase 1a(gene name synonym)|uniprotkb:SAPK1A(gene name synonym) psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350294|imex:IM-20259-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006714954.1|refseq:NP_001128516.1|refseq:NP_002743.3|refseq:NP_620707.1|ensembl:ENSG00000050748(gene)|ensembl:ENST00000452135(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|refseq:NP_620708.1|refseq:NP_620709.1|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P45984|rcsb pdb:3E7O|rcsb pdb:3NPC|rcsb pdb:7CML|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341|refseq:NP_001295173.1|dip:DIP-270N|refseq:XP_016865127.1|refseq:XP_016865130.1 ensembl:ENSP00000269260|ensembl:ENST00000346341|ensembl:ENSP00000341895|ensembl:ENST00000381488|ensembl:ENSP00000370898|ensembl:ENST00000412477|ensembl:ENSP00000403701|ensembl:ENSG00000141480(gene)|ensembl:ENST00000269260(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR017864|go:"GO:0005634"(nucleus)|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0005886"(plasma membrane)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:0007212"(dopamine receptor signaling pathway)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|go:"GO:0007420"(brain development)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007628"(adult walking behavior)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001316993.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|dip:DIP-40089N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ljhZd5mc0kj5al142zo5Me2J26w9606 rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606 intact-crc:39E12026D6DB90D3|rigid:KH01spl+0hROWjRBvBpY8gbeoMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14324 uniprotkb:Q9NRA8 intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350302|imex:IM-20259-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 intact-crc:047320EB901B5D4C|rigid:BWMZuP9vLAUPk9d4pAgfGERj5eM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NR22 uniprotkb:Q9NR22 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350298|imex:IM-20259-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 intact-crc:62E5E17E6C53DEDF|rigid:4EM8YY1nmBLwantqup/ZsLsog1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25786 uniprotkb:Q5JR59 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 intact:EBI-742948|ensembl:ENSP00000483729|uniprotkb:O94872|uniprotkb:Q08E97|uniprotkb:Q5JQR3|uniprotkb:Q8N5E2|uniprotkb:B4DF81|uniprotkb:A7E292 psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:mtus2_human(display_long)|uniprotkb:TIP150(gene name synonym)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350306|imex:IM-20259-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N refseq:NP_001028774.2|refseq:NP_056048.1|ensembl:ENSG00000132938(gene)|ensembl:ENST00000612955(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR033339|mint:Q5JR59|ensembl:ENST00000380808|ensembl:ENSP00000370186|ensembl:ENST00000542829|ensembl:ENSP00000445403|ensembl:ENSP00000483729 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rogid:mC6V+TBEtOpFLeNXq09unF0p6N49606 intact-crc:F55E93A1391C9304|rigid:949pKe1qtyVXemNyfFpQpEsOSko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:P25786 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350310|imex:IM-20259-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:765BA9B10A7ED460|rigid:zearIaQCmkRKaXIClugj4vy/COU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95073 uniprotkb:P25786 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350314|imex:IM-20259-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:F5044E9E5C2E3AB1|rigid:Pyhni460ZrhWF+l5Ghut+YfBF3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25786 uniprotkb:P36406 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350318|imex:IM-20259-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:8C0A672C0C09E1A6|rigid:0gLfimvvCRNzEoYV0FP14yKmEKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPX1 uniprotkb:P25786 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350322|imex:IM-20259-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:22A16D209B2B3114|rigid:kPwkQX85M7xtALb2KlIIOLJhm0Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62191 uniprotkb:Q13200 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350326|imex:IM-20259-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:FE044F506B544043|rigid:kENZn4mpZxbg8X5MvSIoEfoILDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q9NR21 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-748917|uniprotkb:Q68DS1|uniprotkb:Q8N5Y9|uniprotkb:B4DRQ0|ensembl:ENSP00000228820|uniprotkb:F8WBZ7 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:par11_human(display_long)|uniprotkb:PARP11(gene name)|psi-mi:PARP11(display_short)|uniprotkb:C12orf6(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 11(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 11(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350330|imex:IM-20259-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001273450.1|refseq:NP_001273451.1|refseq:NP_065100.2|refseq:XP_005253768.1|refseq:XP_011519272.1|refseq:XP_011519273.1|refseq:XP_011519275.1|refseq:XP_016875159.1|refseq:XP_016875160.1|ensembl:ENSG00000111224(gene)|ensembl:ENST00000228820(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR037197|rcsb pdb:2DK6 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:Trx2/F5euYxQbxo7rGNbvIKCnq89606 intact-crc:5A9263C0A3E7594A|rigid:qaYTuwo7kANlSUwa85PL4szE8m0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:Q9H8E8 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-750907|uniprotkb:Q96GW6|uniprotkb:Q96IH3|uniprotkb:Q9HBF0|uniprotkb:Q9UIY5|uniprotkb:A2A2I5|ensembl:ENSP00000366909|ensembl:ENSP00000392318|ensembl:ENSP00000424752|ensembl:ENSP00000503109|ensembl:ENSP00000503493|ensembl:ENSP00000504050|ensembl:ENSP00000504276 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:csr2b_human(display_long)|uniprotkb:KAT14(gene name)|psi-mi:KAT14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:CSRP2BP(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350334|imex:IM-20259-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_065397.3|ensembl:ENSG00000149474(gene)|ensembl:ENST00000377681(transcript)|ensembl:ENST00000435364(transcript)|ensembl:ENST00000464792(transcript)|ensembl:ENST00000676935(transcript)|ensembl:ENST00000677174(transcript)|ensembl:ENST00000677266(transcript)|ensembl:ENST00000678772(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030274"(LIM domain binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:Q9H8E8|reactome:R-HSA-3214847 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:/Udl5yqzzDQ9jsscSVJlzcGd/VI9606 intact-crc:5DE020D81D39F863|rigid:NUm8iw08DPcuprbcuiLbSIKaYEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96AQ6 uniprotkb:Q99750 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350338|imex:IM-20259-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:CA9FB9EE89475BB9|rigid:a6AFXwZncdqipx2gHfCF+H6y1Ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3C0 uniprotkb:Q96AQ6 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350342|imex:IM-20259-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 intact-crc:8B10F84947DB91A5|rigid:42Xovt5gGEd8QBeI+P6kzdoXvKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99933 uniprotkb:P36406 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350346|imex:IM-20259-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:99BB5EC74CB33546|rigid:h42u7fG0R9naCG3eRiJtp/nB6PI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P9B6 uniprotkb:Q15645 intact:EBI-746504|uniprotkb:Q9HCG3|uniprotkb:Q9NTE8|uniprotkb:Q8IZ64|ensembl:ENSP00000343635 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:meak7_human(display_long)|uniprotkb:MEAK7(gene name)|psi-mi:MEAK7(display_short)|uniprotkb:KIAA1609(gene name synonym)|uniprotkb:MTOR associated protein, eak-7 homolog(gene name synonym)|uniprotkb:TBC/LysM-associated domain-containing protein 1(gene name synonym)|uniprotkb:TLD domain-containing protein 1(gene name synonym)|uniprotkb:TLDC1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350350|imex:IM-20259-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011521550.1|refseq:XP_011521551.1|refseq:NP_065998.3|ensembl:ENSG00000140950(gene)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032868"(response to insulin)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043200"(response to amino acid)|go:"GO:0150032"(positive regulation of protein localization to lysosome)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|interpro:IPR006571(TLDc)|ensembl:ENST00000343629(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:XP_006721303.1|refseq:XP_005256132.1|refseq:XP_016878999.1|refseq:XP_016879000.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:LDRPOUvJCNZ5eDPvjhfMoNFx98k9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:23AB9FA022028DF6|rigid:K4HCMtFpMG6sr1Lz0pb/7/Xew8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16611 uniprotkb:Q07817 intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym) psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350354|imex:IM-20259-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 intact-crc:15B448164CC4342B|rigid:Vsl19lBLoL75CYE+wO3EE44R3hE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q9GZT8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350358|imex:IM-20259-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:352298C07CBF780B|rigid:xLCziLZY57zjL1HktSyJiBc/PZ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:P22234 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350362|imex:IM-20259-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 intact-crc:3BFBBD115692768B|rigid:zQJJP9eFy6Bu/2a7SinUWKOIxUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:P49366 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350366|imex:IM-20259-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 intact-crc:12AD5460DE98C0A1|rigid:U48noGVWrygIsH2Wjr8mPUJIqvA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:Q8N7W2 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350370|imex:IM-20259-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:5D9D87D1CDC1EA5A|rigid:tSBFf8Ec+v26QGvGipL0Muc+VRM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95073 uniprotkb:Q9GZT8 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350374|imex:IM-20259-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:11D03219D499A8F0|rigid:z4cZ+fC8JcYdD6L91AkS5+xODaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:P15531 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350378|imex:IM-20259-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:0B679BDE59EE95A8|rigid:/a2WG0Sz6ZG7ov9ACC4BDNDtuwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GX9 uniprotkb:Q9GZT8 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350382|imex:IM-20259-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:CAD2F1EA9181FE83|rigid:2vwrnGdWneli5PTwiZCbvJubIFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:P21673 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350386|imex:IM-20259-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:88F1890333F77F04|rigid:5J9dwKGw7Z5heQ4E9p8swwUXTL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96MA1 uniprotkb:Q9GZT8 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350390|imex:IM-20259-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:1B92BF0FF22E1CA8|rigid:jGKRILpYm0WQCY/nbpOY2UY56MY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GZT8 uniprotkb:Q15645 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350394|imex:IM-20259-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:422358C37936EABF|rigid:/WfchBtl4bcwOuQdZcfMKUDbaF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62854 uniprotkb:Q969E8 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 intact:EBI-746981|ensembl:ENSP00000364293 psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:tsr2_human(display_long)|uniprotkb:TSR2(gene name)|psi-mi:TSR2(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350398|imex:IM-20259-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 refseq:NP_477511.1|ensembl:ENSG00000158526(gene)|ensembl:ENST00000375151(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|interpro:IPR019398 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 rogid:Pxy9Lzi0Jtk/725OCbYWo/2FyM49606 intact-crc:9B2D3F010A71146B|rigid:3zfsR9sOAUfGdqnRqhAVeXosMpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6UY14 uniprotkb:Q9Y467 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-746180|uniprotkb:B2RMX6|uniprotkb:B9EGK8|uniprotkb:Q8N656|uniprotkb:Q9Y4G1|ensembl:ENSP00000483562 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:sall2_human(display_long)|uniprotkb:SALL2(gene name)|psi-mi:SALL2(display_short)|uniprotkb:KIAA0360(gene name synonym)|uniprotkb:SAL2(gene name synonym)|uniprotkb:ZNF795(gene name synonym)|uniprotkb:Zinc finger protein 795(gene name synonym)|uniprotkb:Zinc finger protein SALL2(gene name synonym)|uniprotkb:Zinc finger protein Spalt-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350402|imex:IM-20259-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_001278375.1|refseq:NP_005398.2|refseq:NP_001278376.1|ensembl:ENSG00000165821(gene)|ensembl:ENST00000614342(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y467 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:iLP/BSIXETLN/cygMJ/+/bmO1xE9606 intact-crc:B47FD97D33924F8B|rigid:FaKy1T5yblqPV5uK0f/zN311DlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJU6 uniprotkb:Q9H788 intact:EBI-751783|uniprotkb:P84070|uniprotkb:Q6IAI8|uniprotkb:Q96F30|uniprotkb:Q96K74|uniprotkb:Q9HBN8|uniprotkb:Q9NR72|uniprotkb:A4D2I9|uniprotkb:B4DEM2|uniprotkb:C9J7P1|uniprotkb:B4DDP6|intact:EBI-28973053|ensembl:ENSP00000411701 intact:EBI-747035|uniprotkb:Q5XKC1|uniprotkb:Q6NXE9|uniprotkb:Q86YM2|uniprotkb:Q96C88|uniprotkb:Q9H7F7|intact:EBI-2558037|uniprotkb:B4DDR1|ensembl:ENSP00000265807|ensembl:ENSP00000428684 psi-mi:dbnl_human(display_long)|uniprotkb:Drebrin-F(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Cervical SH3P7(gene name synonym)|uniprotkb:HPK1-interacting protein of 55 kDa(gene name synonym)|uniprotkb:Cervical mucin-associated protein(gene name synonym)|uniprotkb:DBNL(gene name)|psi-mi:DBNL(display_short)|uniprotkb:CMAP(gene name synonym)|uniprotkb:SH3P7(gene name synonym)|uniprotkb:PP5423(orf name) psi-mi:sh24a_human(display_long)|uniprotkb:SH2D4A(gene name)|psi-mi:SH2D4A(display_short)|uniprotkb:SH2A(gene name synonym)|uniprotkb:"Protein SH(2)A"(gene name synonym)|uniprotkb:PPP1R38(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 38(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350406|imex:IM-20259-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271242.1|refseq:NP_001271244.1|refseq:NP_001014436.1|refseq:NP_001116428.1|refseq:NP_054782.2|ensembl:ENST00000440166|ensembl:ENSP00000415173|ensembl:ENSP00000411701|ensembl:ENST00000456905|ensembl:ENSP00000416421|ensembl:ENST00000468694|ensembl:ENSP00000417653|ensembl:ENST00000490734|ensembl:ENSP00000417749|ensembl:ENST00000494774|ensembl:ENSP00000419992|ensembl:ENSG00000136279(gene)|ensembl:ENST00000448521(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|interpro:IPR035717|interpro:IPR036028|mint:Q9UJU6|rcsb pdb:1X67|reactome:R-HSA-264870|reactome:R-HSA-6794361|reactome:R-HSA-6798695 refseq:NP_001167630.1|refseq:NP_001167631.1|refseq:NP_071354.2|ensembl:ENSG00000104611(gene)|ensembl:ENST00000265807(transcript)|ensembl:ENST00000519207(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:OOa7vGOHVCiCKA9Wt0YUYGR5cu09606 rogid:e7Zi+tTx/rZ4AXx9lSuBz0BmLqI9606 intact-crc:80BF65E8D2D929F6|rigid:jdorckah2l21ZjDQwFNrY31yiPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99961 uniprotkb:Q9H788 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 intact:EBI-747035|uniprotkb:Q5XKC1|uniprotkb:Q6NXE9|uniprotkb:Q86YM2|uniprotkb:Q96C88|uniprotkb:Q9H7F7|intact:EBI-2558037|uniprotkb:B4DDR1|ensembl:ENSP00000265807|ensembl:ENSP00000428684 psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:sh24a_human(display_long)|uniprotkb:SH2D4A(gene name)|psi-mi:SH2D4A(display_short)|uniprotkb:SH2A(gene name synonym)|uniprotkb:"Protein SH(2)A"(gene name synonym)|uniprotkb:PPP1R38(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 38(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350410|imex:IM-20259-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 refseq:NP_001167630.1|refseq:NP_001167631.1|refseq:NP_071354.2|ensembl:ENSG00000104611(gene)|ensembl:ENST00000265807(transcript)|ensembl:ENST00000519207(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860 - crc64:6E5BE978BC955077 - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rogid:e7Zi+tTx/rZ4AXx9lSuBz0BmLqI9606 intact-crc:E6D8A43708C6F531|rigid:nO/xHRqTHMtJMAuomAYIW+IL5UQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21673 uniprotkb:Q9BYD2 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350414|imex:IM-20259-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606 intact-crc:DFE435BAF072209A|rigid:5G5hS3vbi5LmLCsysl8ahFQAqgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H7E9 uniprotkb:Q99750 intact:EBI-715389|uniprotkb:A6NGC0|uniprotkb:Q96BT8|ensembl:ENSP00000330361 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:ch033_human(display_long)|uniprotkb:C8orf33(gene name)|psi-mi:C8orf33(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350418|imex:IM-20259-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075568.1|ensembl:ENSG00000182307(gene)|ensembl:ENST00000331434(transcript)|interpro:IPR029274|mint:Q9H7E9 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:R2UNBJ/dYewCXrmuO3E9apROd+Q9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:3BC20ED200C9C24D|rigid:c5H0FhuY9a2VoV0g1+nU1ca10PE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q9BV99 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-2350424|uniprotkb:B3KUW0|uniprotkb:D3DWY8|ensembl:ENSP00000339047|ensembl:ENSP00000352642|ensembl:ENSP00000420560 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:lrc61_human(display_long)|uniprotkb:LRRC61(gene name)|psi-mi:LRRC61(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350422|imex:IM-20259-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:XP_006716158.1|refseq:NP_001136400.1|refseq:NP_076431.1|ensembl:ENSG00000127399(gene)|ensembl:ENST00000323078(transcript)|ensembl:ENST00000359623(transcript)|ensembl:ENST00000493307(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:LIU9hAGgEAFLuJqz4NrHn6a0vFc9606 intact-crc:9DC3A0568C334C3D|rigid:x91rUIVqOw17UVHvjBWTAkGHluQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60880 uniprotkb:Q9Y3C0 intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17|ensembl:ENSP00000254976 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym) psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350431|imex:IM-20259-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:NP_003072.2|refseq:NP_570824.1|ensembl:ENSG00000132639(gene)|ensembl:ENST00000254976(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:XP_016883511.1|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|dip:DIP-34554N ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 intact-crc:565B33AEB68274C1|rigid:gD4sD9ytpcGTsmtxXqJ4gd+Fo4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12983 uniprotkb:O60238 intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350435|imex:IM-20259-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2 refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - crc64:53967696EDA005E2 - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2017/06/28 rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:551B8368062EEB9D|rigid:+CMlEG2w64qzjQId5D7P6nS0upc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95073 uniprotkb:Q14241 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-742350|uniprotkb:Q8IXH1|uniprotkb:B2R7Q8|ensembl:ENSP00000395574|ensembl:ENSP00000484196 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:eloa1_human(display_long)|uniprotkb:ELOA(gene name)|psi-mi:ELOA(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:TCEB3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym)|uniprotkb:MSTP059(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350439|imex:IM-20259-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_003189.2|ensembl:ENSG00000011007(gene)|ensembl:ENST00000418390(transcript)|ensembl:ENST00000613537(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0070449"(elongin complex)|go:"GO:0090734"(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|mint:Q14241|rcsb pdb:4HFX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:5gE87SPNXNcx+LQDo1Jwt/t9yfI9606 intact-crc:A000E3B635E781C7|rigid:L3uHlzy9g7uAxPL+K8cWLBewJ1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:P35590 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-2256865|uniprotkb:B5A949|uniprotkb:B5A950|ensembl:ENSP00000361554 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:tie1_human(display_long)|uniprotkb:TIE1(gene name)|psi-mi:TIE1(display_short)|uniprotkb:TIE(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350443|imex:IM-20259-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_005415.1|ensembl:ENSG00000066056(gene)|ensembl:ENST00000372476(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001936"(regulation of endothelial cell proliferation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007498"(mesoderm development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060836"(lymphatic endothelial cell differentiation)|go:"GO:0060854"(branching involved in lymph vessel morphogenesis)|go:"GO:1901201"(regulation of extracellular matrix assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|mint:P35590|rcsb pdb:5N06 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:/tuK6SwU9CCcxFhdQo/rlvlPZRg9606 intact-crc:88B8E626F80B694D|rigid:B60ZsKzcvc2nshgu+Ua0WCzxXnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96MA1 uniprotkb:P50552 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350455|imex:IM-20259-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 intact-crc:C5F7BE1E8CFE20EF|rigid:o+I+ZNjyOlWeV1ldgBSidxQWyls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:P55055 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350447|imex:IM-20259-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 intact-crc:A44A4AFD0CAB4889|rigid:UB+tZRjqtbojEthDGOJITdSzW+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50552 uniprotkb:P21673 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350451|imex:IM-20259-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:4A120B01B25488EF|rigid:YmzYDUSxZhnRWfTVTQv3LqtJ2UQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q15777 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-2350461|uniprotkb:D3DQZ5|uniprotkb:E9PB10|uniprotkb:Q59GE6|ensembl:ENSP00000350833 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:mppd2_human(display_long)|uniprotkb:MPPED2(gene name)|psi-mi:MPPED2(display_short)|uniprotkb:Metallophosphoesterase domain-containing protein 2(gene name synonym)|uniprotkb:C11orf8(gene name synonym)|uniprotkb:FAM1B(gene name synonym)|uniprotkb:Fetal brain protein 239(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350459|imex:IM-20259-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001575.1|refseq:XP_005253167.1|refseq:XP_005253168.1|refseq:XP_005253169.1|refseq:NP_001138871.1|refseq:XP_016873721.1|ensembl:ENSG00000066382(gene)|ensembl:ENST00000358117(transcript)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0016208"(AMP binding)|go:"GO:0019002"(GMP binding)|go:"GO:0030145"(manganese ion binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR024201|interpro:IPR029052|mint:Q15777 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:5Z5lEMdW3jMbovZbzRl+VKelpFc9606 intact-crc:BC18298BAC840B97|rigid:6lTK6XAkNeJE2Zs9D6AymV4GZ2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52737 uniprotkb:Q99750 intact:EBI-749129|intact:EBI-28979907|ensembl:ENSP00000344162 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:zn136_human(display_long)|uniprotkb:ZNF136(gene name)|psi-mi:ZNF136(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350467|imex:IM-20259-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196646(gene)|ensembl:ENST00000343979(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSP00000344162|refseq:NP_003428.1|refseq:NP_001334942.1|refseq:NP_001334943.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xPCe6HPmMLKQd8v9K4qwiHptc6c9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:337B275E1D18E94F|rigid:1mMNX3DNPol3ZDG9rbpjXIBIoM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52737 uniprotkb:Q8NHQ1 intact:EBI-749129|intact:EBI-28979907|ensembl:ENSP00000344162 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:zn136_human(display_long)|uniprotkb:ZNF136(gene name)|psi-mi:ZNF136(display_short) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350471|imex:IM-20259-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196646(gene)|ensembl:ENST00000343979(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSP00000344162|refseq:NP_003428.1|refseq:NP_001334942.1|refseq:NP_001334943.1 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xPCe6HPmMLKQd8v9K4qwiHptc6c9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:CB2E8283EEAC6A90|rigid:9VevDaBc+GC4yKGwYajWeOZXeJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BU76 uniprotkb:Q8NHQ1 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350475|imex:IM-20259-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:C2C29A51B574BFB8|rigid:VMMZFEtneF8ujH0WCqJDL7zkLZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q969V5 uniprotkb:Q92624 intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350479|imex:IM-20259-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:329B65F05FA3A67B|rigid:tZ++17R2PuDO8OzC22aJBeYUl50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q0VDD7 uniprotkb:Q13155 intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49 intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950 psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym) psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350483|imex:IM-20259-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1 refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606 rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606 intact-crc:EDE49BFDE3EF4F0F|rigid:m2zeqai27W1YDAvYC+WtqkVZfwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8W4 uniprotkb:Q9UI14 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350487|imex:IM-20259-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:9D38218EDAF156E8|rigid:V1HtlueHMmJd83kIXvCPGdMzac8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33316 uniprotkb:Q9H8W4 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350491|imex:IM-20259-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:177F38CD49B14E34|rigid:QzHKfr7vJyErMTHGN/mFnr0nkTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8W4 uniprotkb:Q8N7W2 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350495|imex:IM-20259-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:B6CE7DD9056F3D71|rigid:3owNjwJOEEVNdD9JRg2D8AN2ZH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:Q9H8W4 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350499|imex:IM-20259-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:79DC2F3E4A67910A|rigid:+28ltjd9ncyfuhWImQpmMmepAz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKG1 uniprotkb:Q9H8W4 intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350503|imex:IM-20259-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:542A747742F78C66|rigid:50Of/M1XhilwSSjXVf2FOM+xYHk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8W4 uniprotkb:Q9UKJ5 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-741528|ensembl:ENSP00000263921|uniprotkb:B2R639 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:chic2_human(display_long)|uniprotkb:BrX-like translocated in leukemia(gene name synonym)|uniprotkb:CHIC2(gene name)|psi-mi:CHIC2(display_short)|uniprotkb:BTL(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350507|imex:IM-20259-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_036242.1|ensembl:ENSG00000109220(gene)|ensembl:ENST00000263921(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019383|interpro:IPR039735 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:pdPnbCymmDTe6+o8PTDcQT595nY9606 intact-crc:940FA93519F42F88|rigid:DjYgz/pwdG2DANbTmsio7Q+Oyng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8W4 uniprotkb:Q9NS73 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350511|imex:IM-20259-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:3C9B0AFF71295B85|rigid:CHE78vCtqOS4cNGojbvVwjRCbYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10644 uniprotkb:Q9H8W4 intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350515|imex:IM-20259-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:69B929538CCD2040|rigid:I/npVLJrWLCbhxsuC24VPrcVpYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H8W4 uniprotkb:Q9HAF1 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350519|imex:IM-20259-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 intact-crc:DF675B7B614D6988|rigid:tYlRUruw/xcH8OggWqs9lrSNBCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:O95751 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350523|imex:IM-20259-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:2B0DDDB0F58F8A57|rigid:1pDPnxScAc+R75SfA0pD8mR0NbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q9H9D4 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350527|imex:IM-20259-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:C4E1EB992D4135CD|rigid:CMeD+kGCxsHkAnS8q/1sa1ULFWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:Q8NHQ1 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350531|imex:IM-20259-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:87FF16BDA01F84E1|rigid:ajHJwN45mIZHLofRE6B/JDkkyzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86TA1 uniprotkb:P49902 intact:EBI-751703|uniprotkb:Q8NEB4|uniprotkb:Q9H8V4|ensembl:ENSP00000262244 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:mob3b_human(display_long)|uniprotkb:MOB3B(gene name)|psi-mi:MOB3B(display_short)|uniprotkb:MOBKL2B(gene name synonym)|uniprotkb:Mob1 homolog 2b(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2B(gene name synonym)|uniprotkb:C9orf35(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350535|imex:IM-20259-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079037.3|ensembl:ENSG00000120162(gene)|ensembl:ENST00000262244(transcript)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703 ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dMFNTMjJM+gWq3lR6v64Pal5pj89606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:0B5AECF98FE2C504|rigid:Zcr356UTenu6pwppFtFtjL5pCuM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q9H5Z6 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-741626|uniprotkb:A6NNC7|uniprotkb:Q8NBZ4|uniprotkb:Q8TAV7|ensembl:ENSP00000386895 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:f124b_human(display_long)|uniprotkb:FAM124B(gene name)|psi-mi:FAM124B(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350539|imex:IM-20259-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001116251.1|refseq:NP_079061.2|ensembl:ENSG00000124019(gene)|ensembl:ENST00000409685(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|interpro:IPR029380 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:HFD1ZzsJklUdYLe4z2+GKU+Owi89606 intact-crc:9276D22EBCFC2AE2|rigid:xq7p3KB+5oo639bDvOiFzlvYV8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q6ZVK8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350543|imex:IM-20259-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:3AF82383CD9AF6A5|rigid:j55kQipEe1jmC48Fhmjmlj0SBK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:P22234 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350547|imex:IM-20259-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 intact-crc:1D8621FA106416C5|rigid:vT0Zc8UymEoEHM5Ebv4ZOy0IjJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:Q96CN4 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350551|imex:IM-20259-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606 intact-crc:47EACACE418FF208|rigid:B7lG6WL5Be8NBR7bCT85KmVxNxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:P49366 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350555|imex:IM-20259-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 intact-crc:34D0C88B986EA0EF|rigid:B5LmTbTiyrjJ+HOhyq1bLaAb1Lo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33316 uniprotkb:Q6ZVK8 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350559|imex:IM-20259-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:DA515E2EC7E9F951|rigid:1XhqhHNsaC3kh9T4PWetxZwGSy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:P49902 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350563|imex:IM-20259-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:3DFD52A6702F0E20|rigid:FZgQHxpf/aK/ew5cObiPj0qwtIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95073 uniprotkb:Q6ZVK8 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350567|imex:IM-20259-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:37ADAEF2926FC8BE|rigid:CgNbKACrO7i7cihHCwLucJ5gvjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BTE0 uniprotkb:Q6ZVK8 intact:EBI-711919|uniprotkb:Q9BTD0|uniprotkb:Q9Y3T3|uniprotkb:B2R7F0|ensembl:ENSP00000350467 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:nat9_human(display_long)|uniprotkb:Embryo brain-specific protein(gene name synonym)|uniprotkb:NAT9(gene name)|psi-mi:NAT9(display_short)|uniprotkb:EBS(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350571|imex:IM-20259-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056469.2|refseq:NP_001292006.1|refseq:NP_001292007.1|refseq:NP_001292008.1|refseq:NP_001292009.1|refseq:NP_001292010.1|refseq:NP_001292011.1|refseq:NP_001292012.1|refseq:NP_001292013.1|refseq:NP_001292014.1|refseq:NP_001292015.1|refseq:NP_001292016.1|refseq:NP_001292017.1|ensembl:ENSG00000109065(gene)|ensembl:ENST00000357814(transcript)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR039135 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:uBtAvUPRnyCN0NdUxtoJg7d3Ygw9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:613BB7BC7B876ED1|rigid:k/eLnxuPUeZmYk7T/1cLOaAt9hA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GX9 uniprotkb:Q6ZVK8 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350575|imex:IM-20259-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:E220B62107090390|rigid:bnJdFlrXJJVoCwN8OGnWr/Isi5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BPX1 uniprotkb:Q6ZVK8 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350579|imex:IM-20259-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:35D0D7D40D95A447|rigid:FPYbOdDvJDEjg3y/sgRgBpuAHzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:Q8TBN0 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350583|imex:IM-20259-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 intact-crc:CDF20C9AF2177B52|rigid:3B/IipRHezRawv+vtXknf0ZbhVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6ZVK8 uniprotkb:Q15633 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350587|imex:IM-20259-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 intact-crc:2FCAAF9E1C42979D|rigid:vkDCQKhyAUFDTwG4WPPwcd5kJaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q96D16 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744419|uniprotkb:E7EW62|ensembl:ENSP00000481397 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:q96d16_human(display_long)|uniprotkb:FBXL18(gene name)|psi-mi:FBXL18(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350591|imex:IM-20259-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_079239.3|ensembl:ENSG00000155034(gene)|ensembl:ENST00000620087(transcript) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Dd8ExGbE2tnHUljANEx2fT5icX09606 intact-crc:8B760965DCC99B7E|rigid:lM45ixLOacvwwfzpeGl3EyRjvI8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NFT6 uniprotkb:Q99750 intact:EBI-749662|uniprotkb:Q8TEX0|uniprotkb:Q9H912|uniprotkb:Q96B19|uniprotkb:D3DX56|ensembl:ENSP00000323663 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dbf4b_human(display_long)|uniprotkb:ASKL1(gene name synonym)|uniprotkb:DRF1(gene name synonym)|uniprotkb:Activator of S phase kinase-like protein 1(gene name synonym)|uniprotkb:Dbf4-related factor 1(gene name synonym)|uniprotkb:Chiffon homolog B(gene name synonym)|uniprotkb:DBF4B(gene name)|psi-mi:DBF4B(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350595|imex:IM-20259-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079380.2|refseq:NP_663696.1|refseq:XP_011523583.1|refseq:XP_006722165.1|ensembl:ENSG00000161692(gene)|ensembl:ENST00000315005(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|mint:Q8NFT6|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:BdvmDAqRsWqg1qbvLLc/uVtXEiI9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:09BD31995437A4AA|rigid:SC2AlIVpKdeatF++L8D+rVylS3E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:P15407 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350599|imex:IM-20259-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606 intact-crc:FB24135ACF5C36F3|rigid:ZqBw9zHSkzLHqAd20cDmYB9wPBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H078 uniprotkb:Q99750 intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350603|imex:IM-20259-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:45B58C95078372E9|rigid:kOEwwgtvaGOVIMGI4czsMC2hjMQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BSH5 uniprotkb:Q15645 intact:EBI-745201|uniprotkb:B2RD47|ensembl:ENSP00000238379|ensembl:ENSP00000363295 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:hdhd3_human(display_long)|uniprotkb:HDHD3(gene name)|psi-mi:HDHD3(display_short)|uniprotkb:C9orf158(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350607|imex:IM-20259-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112496.1|ensembl:ENSG00000119431(gene)|ensembl:ENST00000238379(transcript)|ensembl:ENST00000374180(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR011949(HAD-superfamily hydrolase, subfamily IA, REG-2-like)|interpro:IPR023214|interpro:IPR036412|interpro:IPR041492|rcsb pdb:3K1Z|refseq:NP_001291439.1|refseq:NP_001291440.1|refseq:NP_001291438.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YX8rSYs8QnEQTmA7uqbY5mrz5nU9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:711D08381F7E948B|rigid:PX9elQ8v6Ex6/c07ZgIsTwtScto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:P48552 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350611|imex:IM-20259-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 intact-crc:CB5BF8F95475A4D6|rigid:lAK4e1G6bb2TYSivIS1vJrfBGCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N6Y0 uniprotkb:Q9UJW9 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350623|imex:IM-20259-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171 refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606 intact-crc:3C8297ED1EE8AC62|rigid:4hk1AXkLx2VSsO/26zqqXbLjEe8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48552 uniprotkb:Q8NHQ1 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350615|imex:IM-20259-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:D53ED2EDF0BF38CE|rigid:pQVodSVVZlKj33wtYnC9fo0M/38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92624 uniprotkb:Q8WWW0 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-367390|uniprotkb:Q5SY32|uniprotkb:Q8WWV9|uniprotkb:Q8WXF4|uniprotkb:Q9BT99|uniprotkb:A8K1E6|ensembl:ENSP00000462099 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:rasf5_human(display_long)|uniprotkb:RAPL(gene name synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350619|imex:IM-20259-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_872604.1|refseq:NP_872605.1|refseq:NP_872606.1|ensembl:ENSG00000266094(gene)|ensembl:ENST00000579436(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033623|mint:Q8WWW0|rcsb pdb:4LGD|rcsb pdb:4OH8|dip:DIP-32490N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:EqQpr1Zt1laHo0Y23CpTVMnl28Y9606 intact-crc:B889F4387D4A94AC|rigid:lMHDH4gLeo0uGOZm4nwD/cgsEhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q96JB6 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-749562|uniprotkb:Q96DY1|uniprotkb:Q96PC0|uniprotkb:Q9H6T5|uniprotkb:Q5W0B3|ensembl:ENSP00000260702 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:loxl4_human(display_long)|uniprotkb:Lysyl oxidase-like protein 4(gene name synonym)|uniprotkb:Lysyl oxidase-related protein C(gene name synonym)|uniprotkb:LOXL4(gene name)|psi-mi:LOXL4(display_short)|uniprotkb:LOXC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350627|imex:IM-20259-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_115587.6|ensembl:ENSG00000138131(gene)|ensembl:ENST00000260702(transcript)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q96JB6|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:yOUffU5WqmaUNvrXvX1ie0RWEG49606 intact-crc:7BF72BC62BD5DE52|rigid:spXMno6EeFv/rlvmYonOHTZAWA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q9BQY4 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350631|imex:IM-20259-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 intact-crc:A7B3C98A85EC8D3A|rigid:PCOXiNbSqdGMD2u2gCxKGeW5+lw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q9BQY4 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350635|imex:IM-20259-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 intact-crc:F6BDA73F252240FA|rigid:PpV4Q5EMiPYrhtBCnaKrFEa6fsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q6UX72 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-1170370|uniprotkb:Q96EK0|ensembl:ENSP00000400157 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:b3gn9_human(display_long)|uniprotkb:B3GNT9(gene name)|psi-mi:B3GNT9(display_short)|uniprotkb:UNQ1922/PRO4397(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350643|imex:IM-20259-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_171608.2|ensembl:ENSG00000237172(gene)|ensembl:ENST00000449549(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0008532"(N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030311"(poly-N-acetyllactosamine biosynthetic process)|interpro:IPR002659(Glycosyl transferase, family 31)|reactome:R-HSA-913709 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:ZM7F4khBcuN/9erExui87yIiXFg9606 intact-crc:BB6077CEF04E8036|rigid:7Ew2bMJ2Jx7znhGAEgObQ1h4FEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q14781 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350639|imex:IM-20259-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:B253EE0F4DC979C2|rigid:Thw1S4/qeodTShbyzC/iajOMLTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15038 uniprotkb:Q96K80 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-742550|ensembl:ENSP00000257940 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:zc3ha_human(display_long)|uniprotkb:ZC3H10(gene name)|psi-mi:ZC3H10(display_short)|uniprotkb:ZC3HDC10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350647|imex:IM-20259-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_116175.1|ensembl:ENSG00000135482(gene)|ensembl:ENST00000257940(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0035198"(miRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|refseq:NP_001290053.1|refseq:NP_001290054.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:ygcb76R50to+us9MwWeu9tIAq1A9606 intact-crc:856113822D0DFBEE|rigid:QZq8ymMgmnwwAhnKMwy4Mor/hMk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96I34 uniprotkb:Q15654 intact:EBI-710402|ensembl:ENSP00000292539|ensembl:ENSP00000391126|uniprotkb:D3DWM5 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:pp16a_human(display_long)|uniprotkb:Myosin phosphatase-targeting subunit 3(gene name synonym)|uniprotkb:PPP1R16A(gene name)|psi-mi:PPP1R16A(display_short)|uniprotkb:MYPT3(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350651|imex:IM-20259-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116291.1|ensembl:ENSG00000160972(gene)|ensembl:ENST00000292539(transcript)|ensembl:ENST00000435887(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0017020"(myosin phosphatase regulator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035304"(regulation of protein dephosphorylation)|interpro:IPR002110(Ankyrin)|interpro:IPR017417(Protein phosphatase 1, regulatory subunits 16A/B, eukaryote)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001316371.1|refseq:NP_001316372.1|refseq:NP_001316373.1|refseq:NP_001316374.1|refseq:XP_016869403.1 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xEjCGLPSfE2zKdM41klRl4kCfZI9606 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:19595459E4079379|rigid:UvkPmtX3tq01Zt39t6yT75XCQ7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:Q13136 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350655|imex:IM-20259-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:322554C649717EB8|rigid:Jj6QmollMzw7DTfikMovv4u8J8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13136 uniprotkb:Q8NHQ1 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350659|imex:IM-20259-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:0230ECF713FA3E0A|rigid:gfAm8Hcw9cRoNVp5qWGKjmyrt40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6UY14 uniprotkb:O75716 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350667|imex:IM-20259-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 intact-crc:155505CFC4AA5226|rigid:fSxVP7/DhCStBDCN9mGZ8qR7MCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N381 uniprotkb:Q9NS73 intact:EBI-749096 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:q8n381_human(display_long)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350663|imex:IM-20259-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107644.1|refseq:NP_003620.3|interpro:IPR000980(SH2 motif)|refseq:NP_001290358.1|interpro:IPR032498|go:"GO:0016301"(kinase activity)|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5up+bOHxuzcfCaL/loToWudUSMw9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:6973DF104D1BB890|rigid:tNtgS30Msr//3dXCEY+Rh507ZUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15372 uniprotkb:Q9P2A4 intact:EBI-709735|ensembl:ENSP00000429931 intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6 psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350671|imex:IM-20259-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606 intact-crc:8D95362E04A360E8|rigid:VYqH0PBL28QcO6Vr8kaARKSUuBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ULZ1 uniprotkb:Q99750 intact:EBI-2350677|uniprotkb:Q8WU89|uniprotkb:Q4VY08|ensembl:ENSP00000391800 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:apel_human(display_long)|uniprotkb:APLN(gene name)|psi-mi:APLN(display_short)|uniprotkb:APEL(gene name synonym)|uniprotkb:APJ endogenous ligand(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350675|imex:IM-20259-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059109.3|ensembl:ENSG00000171388(gene)|ensembl:ENST00000429967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007595"(lactation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031652"(positive regulation of heat generation)|go:"GO:0031704"(apelin receptor binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042756"(drinking behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051461"(positive regulation of corticotropin secretion)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0060183"(apelin receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904022"(positive regulation of G protein-coupled receptor internalization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|interpro:IPR026155|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:sshv16DxSDVM/a2VnhtVpOlDy9c9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:B4D2BBAD246C4749|rigid:SNQY1F7sH+tjfFJWrpvLtwHLJu0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14872 uniprotkb:Q9BXS5 intact:EBI-747024|uniprotkb:Q96CB1|uniprotkb:B2RAK6|ensembl:ENSP00000362127 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 psi-mi:mtf1_human(display_long)|uniprotkb:Transcription factor MTF-1(gene name synonym)|uniprotkb:MRE-binding transcription factor(gene name synonym)|uniprotkb:MTF1(gene name)|psi-mi:MTF1(display_short) psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350689|imex:IM-20259-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005946.2|refseq:XP_011539793.1|ensembl:ENSG00000188786(gene)|ensembl:ENST00000373036(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0010038"(response to metal ion)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:1990079"(cartilage homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029796|interpro:IPR036236|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-5660489|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific) refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:zeQhfLuX3GjfLw1B9P+0Rd4eZ4o9606 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 intact-crc:9391090CA5866DD2|rigid:+A9/RTvV7Q26XEZ7fKjFNpxWz9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BXS5 uniprotkb:O95751 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350685|imex:IM-20259-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:C4E1EE6DB378891D|rigid:ovi2AZAyamdRu9zXWLXfJhVTwFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35125 uniprotkb:Q99750 intact:EBI-954564|uniprotkb:Q15634|uniprotkb:Q86WP6|uniprotkb:Q8IWT4|ensembl:ENSP00000250066|ensembl:ENSP00000460380 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:ubp6_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:TRE2(gene name synonym)|uniprotkb:HRP1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350701|imex:IM-20259-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004496.2|ensembl:ENST00000250066(transcript)|ensembl:ENST00000574788(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR035969|interpro:IPR038765|interpro:IPR028889|ensembl:ENSG00000129204(gene)|refseq:NP_001291213.1|refseq:XP_011522352.1|refseq:XP_011522353.1|refseq:XP_011522354.1|refseq:XP_011522355.1|refseq:XP_011522356.1|refseq:XP_011522357.1|refseq:XP_011522358.1|refseq:XP_011522361.1|refseq:XP_016880779.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:EjN7POQXOUGbHphIDgTYYBqptJE9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:88976D347E40D643|rigid:BUO48jtincB5HV7v5xKXqK73G6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96GV9 uniprotkb:Q99750 intact:EBI-2350695|ensembl:ENSP00000326110|ensembl:ENSP00000421270|ensembl:ENSP00000422836 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:macir_human(display_long)|uniprotkb:MACIR(gene name)|psi-mi:MACIR(display_short)|uniprotkb:C5orf30(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350693|imex:IM-20259-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149988.1|refseq:NP_001303897.1|refseq:NP_001303898.1|ensembl:ENSG00000181751(gene)|ensembl:ENST00000319933(transcript)|ensembl:ENST00000510890(transcript)|ensembl:ENST00000515669(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0015031"(protein transport)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060271"(cilium assembly)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|interpro:IPR029219 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/pvB3D4aGWrMxx5qNz88Q74DRAs9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:6E6E5B07714B7F67|rigid:6jsAa3oYmXkToOkctD+YYvKpO/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43439 uniprotkb:Q99750 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350705|imex:IM-20259-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:FE31783C2C7317B6|rigid:6Ai4K2d8jpYNqWjR9+8yemP+O/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:Q9BS34 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745276|intact:EBI-28980552|ensembl:ENSP00000355459 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zn670_human(display_long)|uniprotkb:ZNF670(gene name)|psi-mi:ZNF670(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350709|imex:IM-20259-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_149990.1|ensembl:ENSP00000355459|ensembl:ENSG00000277462(gene)|ensembl:ENST00000366503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9BS34|reactome:R-HSA-212436 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:rLN4zdWhS14BhRLxojEevuc2Knc9606 intact-crc:3922010D72DE0B4D|rigid:r2EWiUv+9PIce8jahRY3GpPKby4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q4U2R8 uniprotkb:Q92624 intact:EBI-749741|uniprotkb:B2D0R6|uniprotkb:A8MY93|uniprotkb:O95187|uniprotkb:O95742|uniprotkb:Q7LDA0|uniprotkb:Q9NQA6|uniprotkb:Q9NQC2|uniprotkb:Q9UBG6|uniprotkb:Q9UEQ8|uniprotkb:Q8N192|ensembl:ENSP00000367102 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:s22a6_human(display_long)|uniprotkb:Organic anion transporter 1(gene name synonym)|uniprotkb:Renal organic anion transporter 1(gene name synonym)|uniprotkb:PAH transporter(gene name synonym)|uniprotkb:SLC22A6(gene name)|psi-mi:SLC22A6(display_short)|uniprotkb:PAHT(gene name synonym)|uniprotkb:OAT1(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350713|imex:IM-20259-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004781.2|refseq:NP_695008.1|refseq:NP_695009.1|refseq:NP_695010.1|ensembl:ENSG00000197901(gene)|ensembl:ENST00000377871(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015347"(sodium-independent organic anion transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015742"(alpha-ketoglutarate transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043252"(sodium-independent organic anion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097254"(renal tubular secretion)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-561048 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:hAE4k7HdfkEQ4drVBOtmwmRGHPA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:3D447C7BDE4C2458|rigid:Bs2hogWnFHu93CMSP7JFtzxsGZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P2A4 uniprotkb:Q9NSC5 intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350721|imex:IM-20259-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4 ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:E21770E8CA8BA1DF|rigid:iX1dl5QpwdPYrze5Lm3JNCs6pOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI14 uniprotkb:Q14088 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350717|imex:IM-20259-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:E97stXWvkGPUamSzsiejNoY4S789606 intact-crc:73C4BB32528EA211|rigid:Ac4U/nds3nAuhLfiUivGIxKT/ao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NRA8 uniprotkb:O60573 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350729|imex:IM-20259-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 intact-crc:AD27C36A8E980559|rigid:ONAv64ZsDxcEWzgaDct7GZWJcQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:O60573 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350725|imex:IM-20259-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 intact-crc:4AA40CEABC900D49|rigid:8olfyGESn/Vha3/gRUE19n3vADI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92530 uniprotkb:Q8N7W2 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350733|imex:IM-20259-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:0D9D3CD4EFA13418|rigid:YkEW55SeCj3wQi0pxkmBYWhGRJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95751 uniprotkb:Q92530 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350741|imex:IM-20259-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:C28F6E33A0A99863|rigid:prdiGQU1tu0b1I+wMHguz6OrFAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92530 uniprotkb:O43251 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350737|imex:IM-20259-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 intact-crc:D040D89468550E89|rigid:sxnqSEJY9bNXlruxVMg3hiy7U+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P286 uniprotkb:Q92530 intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350745|imex:IM-20259-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1 refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2017/06/28 rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:BFE116F41772DD78|rigid:xnUJnGPBQOfOXebXeLsCkvMoYVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:Q9UI14 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350749|imex:IM-20259-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:FDCF645EFB680A1A|rigid:QQ7/P3SIvRD/GVYrdvrwPOgxdpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22234 uniprotkb:P51116 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350753|imex:IM-20259-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:DFD6D19927F15BE1|rigid:WF2JcoPmSVn4yK5uiEnbVNMRIdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:P49902 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350757|imex:IM-20259-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:FFADA2C547BA4304|rigid:ygYmKOIbpkQ4xldTaBfD+w0BQCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15041 uniprotkb:P51116 intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350761|imex:IM-20259-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:94D5A72C9F3412AC|rigid:jB4s95tqsqv5w2wJxvTg4fhKdcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36406 uniprotkb:P51116 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350769|imex:IM-20259-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:28B593358C4486BA|rigid:vJ3eZ+BX7BBvk9tYbZI4jPc03Is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:O95751 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350765|imex:IM-20259-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:76A2B9BEF3AA6B4B|rigid:mf7a8+RUdj6sUmGK/EsqGcHBXPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NS73 uniprotkb:P51116 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350777|imex:IM-20259-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:5C6C4F2F50B00777|rigid:rgmjIdSL7wKWGtbUz2NkaVUzHsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:P15531 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350773|imex:IM-20259-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:EF4AF756288DB8C2|rigid:16jCoZwOCQ8jVi3mIRoUn7pPyf0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51116 uniprotkb:Q03393 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350781|imex:IM-20259-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 intact-crc:93079CC2FB302565|rigid:aInqzdOHHpgP03GkXniJmnG9xeY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9HAF1 uniprotkb:P51116 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350785|imex:IM-20259-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:BF901EAB40D4357A|rigid:JwKG5VaPI4SP3fZz7h6AaRaM1+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99988 uniprotkb:Q99750 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350789|imex:IM-20259-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:8ABF8E95BF309363|rigid:zB2V95ynBl+IfWVjoN4n+6XpmuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15645 uniprotkb:Q15013 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350793|imex:IM-20259-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:11174680FC0A6656|rigid:jkJRGdox7pnZgRBGxhvxnW9SXA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:O43167 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744471|uniprotkb:Q17RC6|uniprotkb:Q5TED5|uniprotkb:Q8N455|ensembl:ENSP00000230122 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zbt24_human(display_long)|uniprotkb:Zinc finger protein 450(gene name synonym)|uniprotkb:ZBTB24(gene name)|psi-mi:ZBTB24(display_short)|uniprotkb:KIAA0441(gene name synonym)|uniprotkb:ZNF450(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350801|imex:IM-20259-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001157785.1|refseq:NP_055612.2|ensembl:ENSG00000112365(gene)|ensembl:ENST00000230122(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O43167|interpro:IPR000210(BTB/POZ-like) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:78JpKudyjkcnvRT5hMeTyp9rXnU9606 intact-crc:FAD89C77EE34F1AD|rigid:ux5tyR5xsv2ONCxW5UXQP01hkF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99750 uniprotkb:O15015 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745608|uniprotkb:Q8IVD8|ensembl:ENSP00000300850 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zn646_human(display_long)|uniprotkb:KIAA0296(gene name synonym)|uniprotkb:ZNF646(gene name)|psi-mi:ZNF646(display_short) psi-mi:"MI:0397"(two hybrid array) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350797|imex:IM-20259-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_055514.3|refseq:XP_011544292.1|ensembl:ENSG00000167395(gene)|ensembl:ENST00000300850(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_005255767.1|refseq:XP_005255768.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2019/07/08 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:LLCOZY29R+2cHozH65lymJNIjRU9606 intact-crc:DC37B206A10D2069|rigid:ayJVYJcoGWhzsORFRtb8FASZUkQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12815 uniprotkb:P36406 intact:EBI-2349743|uniprotkb:Q8N5B2|uniprotkb:F8VSF9|uniprotkb:Q6PJU7|ensembl:ENSP00000257909 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:troap_human(display_long)|uniprotkb:TROAP(gene name)|psi-mi:TROAP(display_short)|uniprotkb:Trophinin-assisting protein(gene name synonym)|uniprotkb:Trophinin-associated protein(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350813|imex:IM-20259-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011536027.1|refseq:NP_001094090.1|refseq:NP_005471.3|refseq:NP_001265253.1|dip:DIP-52951N|ensembl:ENSG00000135451(gene)|ensembl:ENST00000257909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|interpro:IPR026133|mint:Q12815 refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9+3f9EdjzudEOEIYnDMmZGrjjKA9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:9F9EE90E79437062|rigid:xTDE7aOjCGQrrPsiR1YNDOoGwpM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EZ8 uniprotkb:Q9Y3C0 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350817|imex:IM-20259-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 intact-crc:8C5970592B0C0377|rigid:/0LfZB/nt59LYnnK+9S0COGeAnU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EZ8 uniprotkb:Q96CN9 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350825|imex:IM-20259-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 intact-crc:985269C7FAF18813|rigid:WHKXHUV8FtPwmP19ywyD6xCK9Po false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EZ8 uniprotkb:Q86WP2 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 intact:EBI-2349758|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285|ensembl:ENSP00000421202 psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350821|imex:IM-20259-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 ensembl:ENST00000264779|ensembl:ENSP00000264779|ensembl:ENSP00000421202|ensembl:ENST00000511209|ensembl:ENSP00000422337|ensembl:ENST00000514387|ensembl:ENSP00000421709|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|ensembl:ENSG00000062194(gene)|ensembl:ENST00000506184(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028128|mint:Q86WP2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606 intact-crc:B568E3110AB05B93|rigid:YI2UjYAFVOm7hI6GX7+cHXVXkHo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60506 uniprotkb:Q9NR22 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350833|imex:IM-20259-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 intact-crc:EF8C9F7D60309A6F|rigid:V0LMA3aDPAmjPU/edNJJiSTnSHQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q9UI95 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350829|imex:IM-20259-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:687620AC8CF5566F|rigid:PlS7fGlPgEuGtemXGj+bRQVWM58 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95630 uniprotkb:Q15645 intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350845|imex:IM-20259-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JUvszgPz9rog/OEpmABJ295BaLw9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:8D96750B1F59F7E8|rigid:Wexod88ov5GqjGI6C7lU83GdbAY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75886 uniprotkb:O95630 intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904 intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864 psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym) psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350841|imex:IM-20259-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005834.4|ensembl:ENSG00000115145(gene)|ensembl:ENST00000263904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729 refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606 rogid:JUvszgPz9rog/OEpmABJ295BaLw9606 intact-crc:C32F137C99FBFE99|rigid:8o6NFuNsWkLxC6kcCKmnj1qFBeg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q9UI14 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350837|imex:IM-20259-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:BAF695DB65FEAFD4|rigid:aeSpFjgE/USVxzIc2cNzNfpW63s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q00587 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744130|uniprotkb:Q96GN1|uniprotkb:A8K825|ensembl:ENSP00000249014 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:borg5_human(display_long)|uniprotkb:Binder of Rho GTPases 5(gene name synonym)|uniprotkb:Serum protein MSE55(gene name synonym)|uniprotkb:CEP1(gene name synonym)|uniprotkb:MSE55(gene name synonym)|uniprotkb:CDC42EP1(gene name)|psi-mi:CDC42EP1(display_short)|uniprotkb:BORG5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350853|imex:IM-20259-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_689449.1|refseq:XP_006724170.1|refseq:XP_006724171.1|refseq:XP_006724172.1|ensembl:ENSG00000128283(gene)|ensembl:ENST00000249014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_016884030.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Ros/Dvfb6rdmhUyT755WtSswQjQ9606 intact-crc:4F2F67AFC001708B|rigid:IVC+j2DJfCgXYYGgEYlXves5+k4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NTK1 uniprotkb:P36406 intact:EBI-742731|uniprotkb:Q76MX8|uniprotkb:O94997|uniprotkb:Q5T735|ensembl:ENSP00000298295|uniprotkb:B2R6A1 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:depp1_human(display_long)|uniprotkb:DEPP1(gene name)|psi-mi:DEPP1(display_short)|uniprotkb:C10orf10(gene name synonym)|uniprotkb:DEPP(gene name synonym)|uniprotkb:Decidual protein induced by progesterone(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fasting-induced gene protein(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350849|imex:IM-20259-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008952.1|ensembl:ENSG00000165507(gene)|ensembl:ENST00000298295(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR020133 refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dXIt8uYiDcsvDPGDjY0UZwwrsTw9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:DB0554E6ECCA13A9|rigid:AWoumXlrHl+R0tmbjYA/ul9s31U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12841 uniprotkb:Q92624 intact:EBI-2349801|uniprotkb:Q549Z0|uniprotkb:A8K523|uniprotkb:B4DTT5|uniprotkb:D3DN90|ensembl:ENSP00000295633 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:fstl1_human(display_long)|uniprotkb:FSTL1(gene name)|psi-mi:FSTL1(display_short)|uniprotkb:FRP(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350857|imex:IM-20259-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009016.1|ensembl:ENSG00000163430(gene)|ensembl:ENST00000295633(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058|reactome:R-HSA-201451|reactome:R-HSA-381426|reactome:R-HSA-8957275 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:2Y10WyTpml76Ksjw+X7dXUozFg09606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:B0C5A446F1175E00|rigid:fLIzrpHxGAdhl7FQBSB5LZ6uQAY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:Q9UNA4 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-741774|ensembl:ENSP00000462664|uniprotkb:Q8N590|uniprotkb:Q9H0S1|uniprotkb:Q9NYH6 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:poli_human(display_long)|uniprotkb:Eta2(gene name synonym)|uniprotkb:RAD30 homolog B(gene name synonym)|uniprotkb:POLI(gene name)|psi-mi:POLI(display_short)|uniprotkb:RAD30B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350861|imex:IM-20259-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW rcsb pdb:1T3N|rcsb pdb:1ZET|rcsb pdb:2ALZ|rcsb pdb:2DPI|rcsb pdb:2DPJ|rcsb pdb:2FLL|rcsb pdb:2FLN|rcsb pdb:2FLP|rcsb pdb:2KHU|rcsb pdb:2KHW|rcsb pdb:2KTF|rcsb pdb:2L0F|rcsb pdb:2L0G|rcsb pdb:2MBB|rcsb pdb:3EPG|rcsb pdb:3EPI|rcsb pdb:3G6V|rcsb pdb:3G6X|rcsb pdb:3G6Y|rcsb pdb:3GV5|rcsb pdb:3GV7|rcsb pdb:3GV8|rcsb pdb:3H40|rcsb pdb:3H4B|rcsb pdb:3H4D|ensembl:ENSG00000101751(gene)|ensembl:ENST00000579534(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0019985"(translesion synthesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR017961|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|mint:Q9UNA4|refseq:NP_009126.2|rcsb pdb:3NGD|rcsb pdb:3OSN|rcsb pdb:3Q8P|rcsb pdb:3Q8Q|rcsb pdb:3Q8R|rcsb pdb:3Q8S|rcsb pdb:4EBC|rcsb pdb:4EBD|rcsb pdb:4EBE|rcsb pdb:4EYI|rcsb pdb:4FS1|rcsb pdb:4FS2|rcsb pdb:5KT2|rcsb pdb:5KT3|rcsb pdb:5KT4|rcsb pdb:5KT5|rcsb pdb:5KT6|rcsb pdb:5KT7|rcsb pdb:5ULW|rcsb pdb:5ULX|reactome:R-HSA-5656121|reactome:R-HSA-5656169|rcsb pdb:4EYH - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:iH6WfDK+UIzw5XQSHo9wWSfnrJU9606 intact-crc:40691D2EC88D8C85|rigid:cLSSsY1itcdcZ+0Wn1YEettlLTw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96PV6 uniprotkb:Q96MA1 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350869|imex:IM-20259-254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 intact-crc:B95184F004DFE408|rigid:vXtXnuzj04qq7RsfxBxMGZg3H/c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q9UNA4 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-741774|ensembl:ENSP00000462664|uniprotkb:Q8N590|uniprotkb:Q9H0S1|uniprotkb:Q9NYH6 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:poli_human(display_long)|uniprotkb:Eta2(gene name synonym)|uniprotkb:RAD30 homolog B(gene name synonym)|uniprotkb:POLI(gene name)|psi-mi:POLI(display_short)|uniprotkb:RAD30B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350865|imex:IM-20259-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 rcsb pdb:1T3N|rcsb pdb:1ZET|rcsb pdb:2ALZ|rcsb pdb:2DPI|rcsb pdb:2DPJ|rcsb pdb:2FLL|rcsb pdb:2FLN|rcsb pdb:2FLP|rcsb pdb:2KHU|rcsb pdb:2KHW|rcsb pdb:2KTF|rcsb pdb:2L0F|rcsb pdb:2L0G|rcsb pdb:2MBB|rcsb pdb:3EPG|rcsb pdb:3EPI|rcsb pdb:3G6V|rcsb pdb:3G6X|rcsb pdb:3G6Y|rcsb pdb:3GV5|rcsb pdb:3GV7|rcsb pdb:3GV8|rcsb pdb:3H40|rcsb pdb:3H4B|rcsb pdb:3H4D|ensembl:ENSG00000101751(gene)|ensembl:ENST00000579534(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:0019985"(translesion synthesis)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001126(UMUC-like DNA-repair protein)|interpro:IPR017961|interpro:IPR036775|interpro:IPR043128|interpro:IPR043502|mint:Q9UNA4|refseq:NP_009126.2|rcsb pdb:3NGD|rcsb pdb:3OSN|rcsb pdb:3Q8P|rcsb pdb:3Q8Q|rcsb pdb:3Q8R|rcsb pdb:3Q8S|rcsb pdb:4EBC|rcsb pdb:4EBD|rcsb pdb:4EBE|rcsb pdb:4EYI|rcsb pdb:4FS1|rcsb pdb:4FS2|rcsb pdb:5KT2|rcsb pdb:5KT3|rcsb pdb:5KT4|rcsb pdb:5KT5|rcsb pdb:5KT6|rcsb pdb:5KT7|rcsb pdb:5ULW|rcsb pdb:5ULX|reactome:R-HSA-5656121|reactome:R-HSA-5656169|rcsb pdb:4EYH - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:iH6WfDK+UIzw5XQSHo9wWSfnrJU9606 intact-crc:9FDCD4E5EC52002A|rigid:nDXE/GzIBTHq8pYnx33WFnPXl68 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NDC0 uniprotkb:Q96PV6 intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350873|imex:IM-20259-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653 refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:CX220vB2TjggPEso5CHNUVzl79g9606 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 intact-crc:2FF31C059A9EC397|rigid:kf6+zGwWj6wA5X9apQRZ8E02ads false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q96A09 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-752030|ensembl:ENSP00000289166 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:tet5b_human(display_long)|uniprotkb:TENT5B(gene name)|psi-mi:TENT5B(display_short)|uniprotkb:FAM46B(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350877|imex:IM-20259-256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_443175.2|ensembl:ENSG00000158246(gene)|ensembl:ENST00000289166(transcript)|go:"GO:0048255"(mRNA stabilization)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR012937(Protein of unknown function DUF1693) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:hcI1m66Kt1B5RS3kqXhFmu0lNrg9606 intact-crc:791B82349470144C|rigid:eGyMUfqIh9SUEwWe+pyqE9+J7SY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q969Q4 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-751892|ensembl:ENSP00000282026 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:arl11_human(display_long)|uniprotkb:ADP-ribosylation factor-like tumor suppressor protein 1(gene name synonym)|uniprotkb:ARL11(gene name)|psi-mi:ARL11(display_short)|uniprotkb:ARLTS1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350881|imex:IM-20259-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_612459.1|refseq:XP_005266310.1|ensembl:ENSG00000152213(gene)|ensembl:ENST00000282026(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:8Cdo1tj4uifARGdcn7/lC76OAqU9606 intact-crc:59E28E4ACF066243|rigid:6Lq9jyKNeoiQsbN2deC9FsjRcPw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96QF0 uniprotkb:Q8TBN0 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350889|imex:IM-20259-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 intact-crc:63A7313FEBDA8282|rigid:ya6KnFVg/TG0Xjyx/I7xBdiqEmo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q8N1L9 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-742695|uniprotkb:Q96EH4|uniprotkb:Q8NAF4|intact:EBI-945729|uniprotkb:Q8NAL8|ensembl:ENSP00000301887|uniprotkb:D9IC56 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:batf2_human(display_long)|uniprotkb:BATF2(gene name)|psi-mi:BATF2(display_short)|uniprotkb:Suppressor of AP-1 regulated by IFN(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350885|imex:IM-20259-258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_612465.3|refseq:NP_001287736.1|refseq:NP_001287737.1|ensembl:ENSG00000168062(gene)|ensembl:ENST00000301887(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029857|dip:DIP-48662N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:uL+kdibEI8CV/k5zjBeezZNzeAY9606 intact-crc:9454D9579BACB5DD|rigid:mMi45yWuLqK8c/5JjGQ7u2CD2rE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96C03 uniprotkb:Q9UI14 intact:EBI-750153|uniprotkb:Q6ZRD4|uniprotkb:Q96N07|uniprotkb:J3KPT3|ensembl:ENSP00000323591|ensembl:ENSP00000491181 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:mid49_human(display_long)|uniprotkb:MIEF2(gene name)|psi-mi:MIEF2(display_short)|uniprotkb:MID49(gene name synonym)|uniprotkb:Mitochondrial elongation factor 2(gene name synonym)|uniprotkb:SMCR7(gene name synonym)|uniprotkb:Smith-Magenis syndrome chromosomal region candidate gene 7 protein(gene name synonym)|uniprotkb:Mitochondrial dynamics protein of 49 kDa(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350893|imex:IM-20259-260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138372.1|refseq:NP_631901.2|refseq:NP_683684.2|ensembl:ENSG00000177427(gene)|ensembl:ENSG00000284495(gene)|ensembl:ENST00000323019(transcript)|ensembl:ENST00000640122(transcript)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR024810|rcsb pdb:5WP9 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6/vE89OUApM4jmEn3byKeAkZKEw9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:4892F256C21843A9|rigid:7HYI8R5qBD/kABGEVQSVT/IZeMg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WWR8 uniprotkb:Q99750 intact:EBI-746964|uniprotkb:Q96D64|uniprotkb:A8K056|ensembl:ENSP00000375830|ensembl:ENSP00000384804|ensembl:ENSP00000385402|ensembl:ENSP00000478409|ensembl:ENSP00000483726|ensembl:ENSP00000486602|uniprotkb:J3KNJ5 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:neur4_human(display_long)|uniprotkb:N-acetyl-alpha-neuraminidase 4(gene name synonym)|uniprotkb:NEU4(gene name)|psi-mi:NEU4(display_short)|uniprotkb:LP5125(orf name) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350901|imex:IM-20259-262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161072.1|refseq:NP_001161073.1|refseq:NP_001161074.1|refseq:NP_542779.2|ensembl:ENSG00000204099(gene)|ensembl:ENSG00000277926(gene)|ensembl:ENST00000391969(transcript)|ensembl:ENST00000405370(transcript)|ensembl:ENST00000407683(transcript)|ensembl:ENST00000618866(transcript)|ensembl:ENST00000621851(transcript)|ensembl:ENST00000630923(transcript)|go:"GO:0004308"(exo-alpha-sialidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019866"(organelle inner membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0052794"("exo-alpha-(2->3)-sialidase activity")|go:"GO:0052795"("exo-alpha-(2->6)-sialidase activity")|go:"GO:0052796"("exo-alpha-(2->8)-sialidase activity")|interpro:IPR026856|interpro:IPR026946|interpro:IPR036278|reactome:R-HSA-1660662|reactome:R-HSA-4085001|interpro:IPR011040(Neuraminidase)|refseq:NP_001161071.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/7pEb6MVBog4FRBxjxtwP8+E3TM9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:769429889EFF3F00|rigid:2ns3WvoQUMgYnR2FUWvbX/VIwk4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P27658 uniprotkb:Q6UY14 intact:EBI-747133|uniprotkb:Q96D07|uniprotkb:Q53XI6|uniprotkb:D3DN42|ensembl:ENSP00000261037|ensembl:ENSP00000273342|ensembl:ENSP00000498483 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 psi-mi:co8a1_human(display_long)|uniprotkb:Endothelial collagen(gene name synonym)|uniprotkb:COL8A1(gene name)|psi-mi:COL8A1(display_short)|uniprotkb:C3orf7(gene name synonym) psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350897|imex:IM-20259-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001841.2|refseq:NP_065084.2|ensembl:ENSG00000144810(gene)|ensembl:ENST00000261037(transcript)|ensembl:ENST00000273342(transcript)|ensembl:ENST00000652472(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005591"(collagen type VIII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|mint:P27658|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-8948216|go:"GO:0030198"(extracellular matrix organization) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:7doqmNP4HDwd5sPaFgMCUHg4lLA9606 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 intact-crc:26DA756E24333C95|rigid:b/Rodlv+qwUVqVvD96DGt0cMaMU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96Q35 uniprotkb:O00204 intact:EBI-750451|intact:EBI-1755548|uniprotkb:G5E9S3|uniprotkb:Q53TT6|uniprotkb:Q8N1B6|ensembl:ENSP00000286190|ensembl:ENSP00000385098 intact:EBI-749441|uniprotkb:O00205|uniprotkb:O75814|ensembl:ENSP00000201586 psi-mi:facc1_human(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym) psi-mi:st2b1_human(display_long)|uniprotkb:Alcohol sulfotransferase(gene name synonym)|uniprotkb:Hydroxysteroid sulfotransferase 2(gene name synonym)|uniprotkb:SULT2B1(gene name)|psi-mi:SULT2B1(display_short)|uniprotkb:HSST2(gene name synonym)|uniprotkb:Sulfotransferase family 2B member 1(gene name synonym)|uniprotkb:Sulfotransferase family cytosolic 2B member 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350905|imex:IM-20259-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120863.1|refseq:NP_631902.2|refseq:NP_001276922.1|ensembl:ENSG00000155749(gene)|ensembl:ENST00000286190(transcript)|ensembl:ENST00000405148(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036126"(sperm flagellum)|interpro:IPR026674 refseq:NP_004596.2|refseq:NP_814444.1|ensembl:ENSG00000088002(gene)|ensembl:ENST00000201586(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004027"(alcohol sulfotransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0015485"(cholesterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0050294"(steroid sulfotransferase activity)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0051923"(sulfation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990239"(steroid hormone binding)|interpro:IPR000863(Sulphotransferase)|interpro:IPR027417|rcsb pdb:1Q1Q|rcsb pdb:1Q1Z|rcsb pdb:1Q20|rcsb pdb:1Q22|reactome:R-HSA-156584 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:duJOMHCkILW7xWaQjgpDCLSHovs9606 rogid:mon2RxBJKz7A1ArPr/poZuguEXE9606 intact-crc:AA3DE704F4DBB46F|rigid:rMmNiL5ghcVdqK2jxFzMx4ssp5Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WV99 uniprotkb:Q15038 intact:EBI-747823|uniprotkb:Q8NB98|ensembl:ENSP00000289528|ensembl:ENSP00000386898|ensembl:ENSP00000411334 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:zfn2b_human(display_long)|uniprotkb:ZFAND2B(gene name)|psi-mi:ZFAND2B(display_short)|uniprotkb:AIRAPL(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein-like protein(gene name synonym) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350909|imex:IM-20259-264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620157.1|refseq:NP_001257928.1|refseq:NP_001257927.1|refseq:XP_016858857.1|ensembl:ENSG00000158552(gene)|ensembl:ENST00000289528(transcript)|ensembl:ENST00000409336(transcript)|ensembl:ENST00000444522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR035896|rcsb pdb:1X4V ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5a4FVFykky/RfCZ4r5cHDhtjh/Q9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:605ACC7DD4D1973C|rigid:OGUYM3h+jQ7zEEblbLmtHVUzvm0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NFR7 uniprotkb:P21673 intact:EBI-2349862|uniprotkb:Q96LM2|uniprotkb:Q3B7I4|uniprotkb:Q3KR41|uniprotkb:Q53TM6|uniprotkb:Q3B7I3|uniprotkb:Q4ZG23|uniprotkb:Q96BN5|uniprotkb:Q4ZG12|uniprotkb:F5H839|ensembl:ENSP00000283233 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:cc148_human(display_long)|uniprotkb:CCDC148(gene name)|psi-mi:CCDC148(display_short) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350913|imex:IM-20259-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620158.3|refseq:NP_001288613.1|refseq:NP_001288614.1|ensembl:ENSG00000153237(gene)|ensembl:ENST00000283233(transcript)|interpro:IPR039902 ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NjaVl6Tg5pjMw8pimdrrDArtDgI9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:C7FA241BFEE7732A|rigid:L+ujniHJf/tEgnfK8wbiVe/haKg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21964 uniprotkb:Q15645 intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350917|imex:IM-20259-266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:E489B8F50198CE76|rigid:844ue2UYWAiJOctHI8nJsDqhJp4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12277 uniprotkb:Q96DX5 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350929|imex:IM-20259-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 intact-crc:C3C9ED9F8DD7B0B2|rigid:EV7wBgPng3pGRJY55LiCSlvdf6M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q8IVS8 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-748515|uniprotkb:Q0P630|uniprotkb:Q2EZ43|uniprotkb:Q6Y2K6|uniprotkb:Q7Z6G5|uniprotkb:Q86YR8|uniprotkb:Q8TED2|uniprotkb:Q8WTY2|ensembl:ENSP00000389175 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:glctk_human(display_long)|uniprotkb:HBeAg-binding protein 4(gene name synonym)|uniprotkb:GLYCTK(gene name)|psi-mi:GLYCTK(display_short)|uniprotkb:HBEBP4(gene name synonym)|uniprotkb:LP5910(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350921|imex:IM-20259-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001138423.1|refseq:NP_660305.2|ensembl:ENSG00000168237(gene)|ensembl:ENST00000436784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008887"(glycerate kinase activity)|go:"GO:0061624"(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|interpro:IPR007835(MOFRL)|interpro:IPR025286|interpro:IPR038614|interpro:IPR039760|reactome:R-HSA-70350 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:bllfV0CGOer8LrNYQtIm+i+mhu09606 intact-crc:B84D147E7E955C88|rigid:oOnPGCcHbKrCP3VB8RzNujt7cqQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92624 uniprotkb:A1XBS5 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-2349888|uniprotkb:Q96L09|uniprotkb:Q6AHW7|uniprotkb:A1XBS4|uniprotkb:Q8N8R1|uniprotkb:Q32ND3|ensembl:ENSP00000429367 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:fa92a_human(display_long)|uniprotkb:FAM92A(gene name)|psi-mi:FAM92A(display_short)|uniprotkb:FAM92A1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350925|imex:IM-20259-268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_001269963.1|refseq:NP_660312.2|ensembl:ENSG00000188343(gene)|ensembl:ENST00000518322(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005814"(centriole)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0061024"(membrane organization)|go:"GO:0097546"(ciliary base)|go:"GO:0097749"(membrane tubulation)|interpro:IPR009602(Protein of unknown function DUF1208)|interpro:IPR027267|interpro:IPR035590|mint:A1XBS5 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:okcFZHR4G4vduKkWaZ0jXyRVZmY9606 intact-crc:D39A4967BB924893|rigid:iAA9Q26/6HhGthuOhDYK1O8Ee+U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:P53672 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-750444|uniprotkb:Q9Y562|uniprotkb:Q4ZFX0|ensembl:ENSP00000295728|ensembl:ENSP00000375946 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:crba2_human(display_long)|uniprotkb:Beta-A2 crystallin(gene name synonym)|uniprotkb:CRYBA2(gene name)|psi-mi:CRYBA2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350937|imex:IM-20259-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_476434.1|refseq:NP_476435.1|ensembl:ENSG00000163499(gene)|ensembl:ENST00000295728(transcript)|ensembl:ENST00000392096(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|go:"GO:0042802"(identical protein binding)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P53672 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:/WkdaQ4LTxa9mpIiOwVuhd375mE9606 intact-crc:E02A25F5E7D3AB05|rigid:Oz76y1wn3BXN/kllwUVpS+XJm8U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NWT6 uniprotkb:Q96DX5 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-745641|uniprotkb:Q9NWS5|uniprotkb:Q9Y4T3|uniprotkb:A8K8A5|ensembl:ENSP00000369855|intact:EBI-2349899|uniprotkb:Q9BVF5 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:asb9_human(display_long)|uniprotkb:ASB9(gene name)|psi-mi:ASB9(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350933|imex:IM-20259-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N refseq:NP_001026909.1|refseq:NP_001162003.1|refseq:NP_076992.1|ensembl:ENST00000380488(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045732"(positive regulation of protein catabolic process)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037333|mint:Q96DX5|rcsb pdb:3D9H|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:6V9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000102048(gene)|refseq:NP_001162002.1|refseq:XP_005274503.1|dip:DIP-52905N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:ptKNzNqGuV3MO9/nIT6RI+w/Jtk9606 intact-crc:8E0F8EC609B2B12F|rigid:zgfqTugrhpF4G0yekOH+6cGfeJA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBX3 uniprotkb:Q99750 intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350941|imex:IM-20259-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:A2DABB0818E166CE|rigid:Ld3t/lXV+Iil7z3Vet3JzPctoiM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:Q8IYI6 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350945|imex:IM-20259-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 intact-crc:06FD4F90FB0F2145|rigid:toK5zaQZX/7NDJmS4VgAwTxdlZA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TBN0 uniprotkb:Q8IYI6 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350949|imex:IM-20259-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 intact-crc:50544BF86F5AA1DF|rigid:g5pB71tutJAs/iak9BHftmxAMEs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IYI6 uniprotkb:Q5JST6 intact:EBI-742102|ensembl:ENSP00000355605|uniprotkb:Q5TE82|uniprotkb:B3KU33 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 psi-mi:exoc8_human(display_long)|uniprotkb:Exocyst complex 84 kDa subunit(gene name synonym)|uniprotkb:EXOC8(gene name)|psi-mi:EXOC8(display_short) psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350953|imex:IM-20259-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000116903(gene)|go:"GO:0031252"(cell leading edge)|ensembl:ENST00000366645(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005770"(late endosome)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_787072.2|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916 ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VXQFBw3zltr9eQ/3EgdLszUZbbs9606 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 intact-crc:6219854F3D83C6A0|rigid:7N1ZBbMp/Q8qXAcKX0H8tH1kAxM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13498 uniprotkb:Q99750 intact:EBI-986058|uniprotkb:Q14090|uniprotkb:Q9BR72|ensembl:ENSP00000261623 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:cy24a_human(display_long)|uniprotkb:p22 phagocyte B-cytochrome(gene name synonym)|uniprotkb:Neutrophil cytochrome b 22 kDa polypeptide(gene name synonym)|uniprotkb:p22-phox(gene name synonym)|uniprotkb:"Cytochrome b(558) alpha chain"(gene name synonym)|uniprotkb:Cytochrome b558 subunit alpha(gene name synonym)|uniprotkb:Superoxide-generating NADPH oxidase light chain subunit(gene name synonym)|uniprotkb:CYBA(gene name)|psi-mi:CYBA(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350957|imex:IM-20259-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000051523(gene)|ensembl:ENST00000261623(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001725"(stress fiber)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003106"(negative regulation of glomerular filtration by angiotensin)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0009055"(electron transfer activity)|go:"GO:0014823"(response to activity)|go:"GO:0014895"(smooth muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016175"("superoxide-generating NAD(P)H oxidase activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0020037"(heme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042493"|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043020"(NADPH oxidase complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045730"(respiratory burst)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904845"(cellular response to L-glutamine)|interpro:IPR007732(Cytochrome b558 alpha-subunit)|mint:P13498|rcsb pdb:1WLP|reactome:R-HSA-1222556|reactome:R-HSA-1236973|reactome:R-HSA-3299685|reactome:R-HSA-4420097|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9673324|refseq:NP_000092.2|dip:DIP-37650N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:FviZIB2lWLr0GrH9y2gxAA6mgCg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:55CACFF475719DD4|rigid:B2I6KMLxUrs9XZmBovNk5ydDemU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06730 uniprotkb:Q9NRA8 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350965|imex:IM-20259-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 intact-crc:2937AEE8A91ADCE3|rigid:Dc1h8DyCQXhYWB2PyiFTWMWOlMo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q96LL4 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-751596|uniprotkb:Q96LJ9|ensembl:ENSP00000297324 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:ch048_human(display_long)|uniprotkb:C8orf48(gene name)|psi-mi:C8orf48(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350961|imex:IM-20259-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001007091.1|ensembl:ENSG00000164743(gene)|ensembl:ENST00000297324(transcript)|interpro:IPR027932|mint:Q96LL4 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:JPB4E+42Jc1w9k0ExNOu0GOi9AQ9606 intact-crc:249859C0C66EA035|rigid:B6uKVGDO+lpHbyFHRtxht5l9cBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92624 uniprotkb:Q6ZMV9 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-751100|uniprotkb:Q2MDE3|uniprotkb:Q2MDE4|uniprotkb:Q5T8J6|uniprotkb:Q6ZWE3|uniprotkb:Q86T87|uniprotkb:Q8WTV4|ensembl:ENSP00000287152 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:kif6_human(display_long)|uniprotkb:KIF6(gene name)|psi-mi:KIF6(display_short)|uniprotkb:C6orf102(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350973|imex:IM-20259-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_659464.3|refseq:XP_011512661.1|refseq:NP_001275953.1|ensembl:ENSG00000164627(gene)|ensembl:ENST00000287152(transcript)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:1990939" - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:LuGQTWtwbNjMg332rMN2II5k6yI9606 intact-crc:C15CFAA0E9E68EAF|rigid:BJbbPgetU8Xg9sgQte1HG7b3FSs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H9L3 uniprotkb:O00423 intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424|ensembl:ENSP00000357202 intact:EBI-751327|uniprotkb:Q86U15|uniprotkb:Q8N536|uniprotkb:Q8N5C4|uniprotkb:Q8WWL6|ensembl:ENSP00000262233 psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name) psi-mi:emal1_human(display_long)|uniprotkb:EML1(gene name)|psi-mi:EML1(display_short)|uniprotkb:EMAP1(gene name synonym)|uniprotkb:EMAPL(gene name synonym)|uniprotkb:EMAPL1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350969|imex:IM-20259-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|reactome:R-HSA-6791226|interpro:IPR037433|mint:Q9H9L3|ensembl:ENSG00000143319(gene)|ensembl:ENST00000313146(transcript)|ensembl:ENST00000368219(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034933|interpro:IPR036397 refseq:NP_001008707.1|refseq:NP_004425.2|ensembl:ENSG00000066629(gene)|ensembl:ENST00000262233(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:O00423|rcsb pdb:4CI8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606 rogid:hfGdCoFa3Miii6W/ozQuZ2cFiHs9606 intact-crc:C16F04660CA70F4C|rigid:zxfJsH5baonkkTZNrQuABN8QN0g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07332 uniprotkb:Q99750 intact:EBI-1055635|uniprotkb:B4DUD0|uniprotkb:E9PC94|uniprotkb:E9PC95|uniprotkb:Q2VXS7|uniprotkb:Q2VXS8|uniprotkb:Q2VXT0|uniprotkb:Q6GTU5|uniprotkb:B2R6E6|ensembl:ENSP00000331504 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:fes_human(display_long)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:p93c-fes(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350977|imex:IM-20259-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137255.1|refseq:NP_001137256.1|refseq:NP_001137257.1|refseq:NP_001996.1|refseq:XP_005254937.1|refseq:XP_005254939.1|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|mint:P07332|rcsb pdb:1WQU|rcsb pdb:2DCR|rcsb pdb:3BKB|rcsb pdb:3CBL|rcsb pdb:3CD3|rcsb pdb:4DYL|rcsb pdb:4E93|rcsb pdb:6JMF|reactome:R-HSA-1433557|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|ensembl:ENSG00000182511(gene)|ensembl:ENST00000328850(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|refseq:XP_016877494.1|refseq:XP_016877495.1|refseq:XP_016877496.1|refseq:XP_016877497.1|refseq:XP_016877498.1|refseq:XP_016877499.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:CCFB572124AEA244|rigid:O80QLi419U1OmSWaq08zbTGzMak false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62070 uniprotkb:Q13671 intact:EBI-491037|uniprotkb:P17082|uniprotkb:B2R9Z3|uniprotkb:B7Z6C4|uniprotkb:B7Z7H6|ensembl:ENSP00000256196|uniprotkb:B7Z5Z2 intact:EBI-366017|uniprotkb:O15010|uniprotkb:Q00427|uniprotkb:Q96CC8|ensembl:ENSP00000310406 psi-mi:rras2_human(display_long)|uniprotkb:Ras-like protein TC21(gene name synonym)|uniprotkb:Teratocarcinoma oncogene(gene name synonym)|uniprotkb:RRAS2(gene name)|psi-mi:RRAS2(display_short)|uniprotkb:TC21(gene name synonym) psi-mi:rin1_human(display_long)|uniprotkb:RIN1(gene name)|psi-mi:RIN1(display_short)|uniprotkb:Ras interaction/interference protein 1(gene name synonym)|uniprotkb:Ras inhibitor JC99(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350981|imex:IM-20259-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036382.2|refseq:NP_001096139.1|refseq:NP_001170786.1|refseq:NP_001170785.1|ensembl:ENSG00000133818(gene)|ensembl:ENST00000256196(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|rcsb pdb:2ERY|reactome:R-HSA-9696273 ensembl:ENSG00000174791(gene)|ensembl:ENST00000311320(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|interpro:IPR000159(Ras-association)|interpro:IPR000980(SH2 motif)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR036860|interpro:IPR037191|reactome:R-HSA-8876198|refseq:NP_004283.2|dip:DIP-117N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WW/YiKaC5t0Qy03E7LQTzpIP9BY9606 rogid:oj/ZbyM0Oqe0wDMlFbJHCtGzMwA9606 intact-crc:B4CA67DDA96EBE6C|rigid:VFn+jhdcLcBpZRY8EN4sYzkG3+M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O94907 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-742864|uniprotkb:B2RC19|ensembl:ENSP00000363081 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:dkk1_human(display_long)|uniprotkb:SK(gene name synonym)|uniprotkb:DKK1(gene name)|psi-mi:DKK1(display_short)|uniprotkb:UNQ492/PRO1008(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350989|imex:IM-20259-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_036374.1|interpro:IPR039863|rcsb pdb:3S2K|rcsb pdb:3S8V|rcsb pdb:3SOQ|rcsb pdb:5FWW|rcsb pdb:5GJE|reactome:R-HSA-201681|reactome:R-HSA-3772470|reactome:R-HSA-5339717|ensembl:ENSG00000107984(gene)|ensembl:ENST00000373970(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0008083"(growth factor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042662"(negative regulation of mesodermal cell fate specification)|go:"GO:0042663"(regulation of endodermal cell fate specification)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045813"(positive regulation of Wnt signaling pathway, calcium modulating pathway)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060173"(limb development)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098883"(synapse pruning)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901296"(negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1904338"(regulation of dopaminergic neuron differentiation)|go:"GO:1904723"(negative regulation of Wnt-Frizzled-LRP5/6 complex assembly)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR006796(Dickkopf, N-terminal cysteine-rich)|dip:DIP-46461N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:OOYhVQDXaaC6AbdFdUKMCjB9L1M9606 intact-crc:BBDF55512F34E488|rigid:5JAgny2PE5pYbkDE/E3/EWXIuQE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WV24 uniprotkb:Q99750 intact:EBI-738731|uniprotkb:Q15184|uniprotkb:Q2TAN2|uniprotkb:Q9NZ17|uniprotkb:A1A4G9|ensembl:ENSP00000266671|ensembl:ENSP00000480767 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:phla1_human(display_long)|uniprotkb:PHLDA1(gene name)|psi-mi:PHLDA1(display_short)|uniprotkb:T-cell death-associated gene 51 protein(gene name synonym)|uniprotkb:Apoptosis-associated nuclear protein(gene name synonym)|uniprotkb:Proline- and histidine-rich protein(gene name synonym)|uniprotkb:Proline- and glutamine-rich protein(gene name synonym)|uniprotkb:PHRIP(gene name synonym)|uniprotkb:TDAG51(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350985|imex:IM-20259-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031376.3|ensembl:ENSG00000139289(gene)|ensembl:ENST00000266671(transcript)|ensembl:ENST00000619060(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045210"(FasL biosynthetic process)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR042832|reactome:R-HSA-8854521 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NS+bTnhkGzSYrQNsSRqehTkl0809606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:773B1B3501473805|rigid:wpXo1PbEWl+IPJnw58U5hd6SZ7Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21673 uniprotkb:Q9BQ70 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-745182|uniprotkb:Q2MK75|uniprotkb:Q9UPV3|ensembl:ENSP00000263346|ensembl:ENSP00000491638 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:tcf25_human(display_long)|uniprotkb:Nuclear localized protein 1(gene name synonym)|uniprotkb:TCF25(gene name)|psi-mi:TCF25(display_short)|uniprotkb:KIAA1049(gene name synonym)|uniprotkb:NULP1(gene name synonym)|uniprotkb:FKSG26(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350993|imex:IM-20259-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N refseq:NP_055787.1|ensembl:ENSG00000141002(gene)|ensembl:ENST00000263346(transcript)|ensembl:ENST00000640279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:1990112"(RQC complex)|interpro:IPR006994(Basic helix-loop-helix, Nulp1-type)|interpro:IPR011990(Tetratricopeptide-like helical) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:+UEKIIV2LaFWrqJiOWgGU74ITVM9606 intact-crc:F9B19770A92197D8|rigid:T4Y21e1OdaoW0M4QBcx9qdnLta0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14687 uniprotkb:Q9P2K3 intact:EBI-372619|uniprotkb:Q8IY61|uniprotkb:Q96GA4|uniprotkb:Q9BW09|uniprotkb:D3DUM4|ensembl:ENSP00000253458 intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972 psi-mi:gse1_human(display_long)|uniprotkb:GSE1(gene name)|psi-mi:GSE1(display_short)|uniprotkb:KIAA0182(gene name synonym) psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351001|imex:IM-20259-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001127945.1|refseq:NP_055430.1|refseq:NP_001265113.1|ensembl:ENSG00000131149(gene)|ensembl:ENST00000253458(transcript)|interpro:IPR022207|interpro:IPR042337 rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:demu8MwWIxvbEfrM+pBn3gDTUO09606 rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606 intact-crc:47153107A817AAE8|rigid:TlugEfoLJACm/9TuUAItQ27l0w4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:Q96HL7 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-749393 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:q96hl7_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2350997|imex:IM-20259-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 interpro:IPR019749|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR029071|interpro:IPR030691|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR035963 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:8FzDjTTcZeOZDZkuoLZy0pjwuKc9606 intact-crc:CF9FA5A1034A4F4C|rigid:LkCYL8wTLNPVAANGkxOsK104AqY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BT88 uniprotkb:Q92624 intact:EBI-751770|uniprotkb:Q14998|uniprotkb:Q68CT5|uniprotkb:Q8IXU3|uniprotkb:Q96SU2|uniprotkb:Q5W0D4|ensembl:ENSP00000357307 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:syt11_human(display_long)|uniprotkb:Synaptotagmin XI(gene name synonym)|uniprotkb:SYT11(gene name)|psi-mi:SYT11(display_short)|uniprotkb:KIAA0080(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351005|imex:IM-20259-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689493.3|ensembl:ENSG00000132718(gene)|ensembl:ENST00000368324(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1900243"(negative regulation of synaptic vesicle endocytosis)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905154"(negative regulation of membrane invagination)|go:"GO:1905162"(regulation of phagosome maturation)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|go:"GO:1905469"(negative regulation of clathrin-coated pit assembly)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028699|interpro:IPR035892|reactome:R-HSA-8856825|reactome:R-HSA-8856828 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+unyxZC+Tuj9r8wtvicjY+Yig+I9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:50BC86282C1C9B47|rigid:mEIa+MwDNQ+ki1Sojl4tU/6VbGE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q96D21 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-2349993|uniprotkb:Q5THY8|uniprotkb:O95520|ensembl:ENSP00000216127 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:rhes_human(display_long)|uniprotkb:RASD2(gene name)|psi-mi:RASD2(display_short)|uniprotkb:TEM2(gene name synonym)|uniprotkb:Ras homolog enriched in striatum(gene name synonym)|uniprotkb:Tumor endothelial marker 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351009|imex:IM-20259-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:XP_011528342.1|refseq:NP_055125.2|refseq:XP_005261499.1|refseq:XP_016884190.1|refseq:XP_016884191.1|ensembl:ENSG00000100302(gene)|ensembl:ENST00000216127(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:gEU7RPbzdPERuaXm8i6CoRjmz/Q9606 intact-crc:CBCD15799448AD78|rigid:+SjGmP2vfhOhWqvrPs7XG0NBzSM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q9UBV8 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-724639|ensembl:ENSP00000362807 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:pef1_human(display_long)|uniprotkb:PEF protein with a long N-terminal hydrophobic domain(gene name synonym)|uniprotkb:Penta-EF hand domain-containing protein 1(gene name synonym)|uniprotkb:PEF1(gene name)|psi-mi:PEF1(display_short)|uniprotkb:ABP32(gene name synonym)|uniprotkb:UNQ1845/PRO3573(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351017|imex:IM-20259-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_036524.1|ensembl:ENSG00000162517(gene)|ensembl:ENST00000373703(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0003723"(RNA binding)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBV8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:HoQa0GPucZdIv5g9+OoHdanlyPo9606 intact-crc:DA022ECC2C2CD9D4|rigid:vLKsKHujiO9uz8MaVQYWuh69/TQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95865 uniprotkb:Q15645 intact:EBI-749139|uniprotkb:A2BEZ7|ensembl:ENSP00000364943|ensembl:ENSP00000364945|ensembl:ENSP00000364949|ensembl:ENSP00000372901|ensembl:ENSP00000382935|ensembl:ENSP00000389552|ensembl:ENSP00000391632|ensembl:ENSP00000391833|ensembl:ENSP00000395372|ensembl:ENSP00000395759|ensembl:ENSP00000397466|ensembl:ENSP00000399023|ensembl:ENSP00000399357|ensembl:ENSP00000402594|ensembl:ENSP00000403154|ensembl:ENSP00000404342|ensembl:ENSP00000404851|ensembl:ENSP00000405515|ensembl:ENSP00000408148|ensembl:ENSP00000409396|ensembl:ENSP00000412327|ensembl:ENSP00000412800|ensembl:ENSP00000382936 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ddah2_human(display_long)|uniprotkb:DDAHII(gene name synonym)|uniprotkb:Dimethylargininase-2(gene name synonym)|uniprotkb:S-phase protein(gene name synonym)|uniprotkb:Protein G6a(gene name synonym)|uniprotkb:DDAH2(gene name)|psi-mi:DDAH2(display_short)|uniprotkb:DDAH(gene name synonym)|uniprotkb:G6A(gene name synonym)|uniprotkb:NG30(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351013|imex:IM-20259-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206395(gene)|ensembl:ENSG00000213722(gene)|ensembl:ENSG00000225635(gene)|ensembl:ENSG00000226634(gene)|ensembl:ENSG00000227317(gene)|ensembl:ENSG00000228128(gene)|ensembl:ENSG00000233076(gene)|refseq:NP_039268.1|refseq:XP_011512750.1|refseq:NP_001289936.1|refseq:NP_001289937.1|ensembl:ENST00000375787(transcript)|ensembl:ENST00000375789(transcript)|ensembl:ENST00000375792(transcript)|ensembl:ENST00000383409(transcript)|ensembl:ENST00000437889(transcript)|ensembl:ENST00000400062(transcript)|ensembl:ENST00000400063(transcript)|ensembl:ENST00000411456(transcript)|ensembl:ENST00000413532(transcript)|ensembl:ENST00000413655(transcript)|ensembl:ENST00000414455(transcript)|ensembl:ENST00000416410(transcript)|ensembl:ENST00000443533(transcript)|ensembl:ENST00000424790(transcript)|ensembl:ENST00000426149(transcript)|ensembl:ENST00000444699(transcript)|ensembl:ENST00000447101(transcript)|ensembl:ENST00000451411(transcript)|ensembl:ENST00000454138(transcript)|ensembl:ENST00000427126(transcript)|go:"GO:0000052"(citrulline metabolic process)|ensembl:ENST00000430482(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005739"(mitochondrion)|ensembl:ENST00000434464(transcript)|ensembl:ENST00000436437(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0016403"(dimethylargininase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR033199|interpro:IPR033202|reactome:R-HSA-203615|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:u/xau/wTFcLGsICADPBRLQWljkk9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:903C82BDB1B53FB0|rigid:4J3Vf3fPc2tGf0WaJCDCMlJcr4c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95073 uniprotkb:O95073 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351021|imex:IM-20259-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 intact-crc:6D485F69C1449465|rigid:ZRn7LzQChXXs5PheOPxqgl6t+h0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6RW13 uniprotkb:Q9UKF7 intact:EBI-741181|ensembl:ENSP00000319713|uniprotkb:A8MVQ5|uniprotkb:Q5SNV4|uniprotkb:Q5SNV5|uniprotkb:Q96AC0|uniprotkb:Q96PL4|uniprotkb:Q9NRW9 intact:EBI-749241|uniprotkb:Q96I07|uniprotkb:A8K473|uniprotkb:J3QR20|ensembl:ENSP00000464006 psi-mi:atrap_human(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:ATRAP(gene name synonym) psi-mi:pitc1_human(display_long)|uniprotkb:Retinal degeneration B homolog beta(gene name synonym)|uniprotkb:Mammalian rdgB homolog beta(gene name synonym)|uniprotkb:PITPNC1(gene name)|psi-mi:PITPNC1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351025|imex:IM-20259-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035284.1|refseq:NP_001035285.1|refseq:NP_001035286.1|refseq:NP_001035287.1|refseq:NP_065083.3|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:Q6RW13|reactome:R-HSA-6802952|ensembl:ENSG00000177674(gene)|ensembl:ENST00000314340(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus) refseq:NP_858057.1|refseq:NP_036549.2|ensembl:ENSG00000154217(gene)|ensembl:ENST00000581322(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901611"(phosphatidylglycerol binding)|go:"GO:1990050"(phosphatidic acid transfer activity)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR023393 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:z+Us8VGLb+tlxNibfVodbuMZ6+89606 rogid:wN3p8shBXRlygSywNjvBMcVNmq89606 intact-crc:9026CD384131E35E|rigid:9Zg3QyAVwJxO4sz3TWCtOFF4nn4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y247 uniprotkb:O95751 intact:EBI-742802|uniprotkb:Q5T2L6|ensembl:ENSP00000369627|ensembl:ENSP00000496837 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:fa50b_human(display_long)|uniprotkb:Protein XAP-5-like(gene name synonym)|uniprotkb:FAM50B(gene name)|psi-mi:FAM50B(display_short)|uniprotkb:X5L(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351029|imex:IM-20259-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036267.1|ensembl:ENST00000380274(transcript)|ensembl:ENST00000648326(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030496"(midbody)|go:"GO:0045171"(intercellular bridge)|interpro:IPR007005(XAP5 protein)|mint:Q9Y247|ensembl:ENSG00000145945(gene)|refseq:XP_016866218.1 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+GYwKGuchxbVElEibszICsOAgFo9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:8B4700CFFEF68301|rigid:khXRxvo6bloVRAWhvxZxU2f7OLo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q8NE01 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-741032|ensembl:ENSP00000305449|uniprotkb:Q8TBV4|uniprotkb:Q96IW4|uniprotkb:Q9NRK4|uniprotkb:Q9NXW6|uniprotkb:B3KX67 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cnnm3_human(display_long)|uniprotkb:Cyclin-M3(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 3(gene name synonym)|uniprotkb:CNNM3(gene name)|psi-mi:CNNM3(display_short)|uniprotkb:ACDP3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351033|imex:IM-20259-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_060093.3|refseq:NP_951060.1|ensembl:ENSG00000168763(gene)|ensembl:ENST00000305510(transcript)|go:"GO:0006811"(ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR044751|mint:Q8NE01|rcsb pdb:5K22|rcsb pdb:5K23|rcsb pdb:5K25|rcsb pdb:5TSR|rcsb pdb:6DFD|rcsb pdb:6MN6|rcsb pdb:6WUR|go:"GO:0005886"(plasma membrane) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:AHuatMC/j3lteiKZli8vu5ZM6vk9606 intact-crc:A6FC2AC115FE5363|rigid:ZWSDWU1KDmiT9YfWRJ53eM0FuLg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GA7 uniprotkb:Q9UGJ1 intact:EBI-744440|ensembl:ENSP00000341117|ensembl:ENSP00000385790 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:sdsl_human(display_long)|uniprotkb:Serine dehydratase 2(gene name synonym)|uniprotkb:SDSL(gene name)|psi-mi:SDSL(display_short)|uniprotkb:L-serine deaminase(gene name synonym)|uniprotkb:L-threonine dehydratase(gene name synonym)|uniprotkb:L-serine dehydratase/L-threonine deaminase(gene name synonym) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351041|imex:IM-20259-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612441.1|refseq:NP_001291922.1|refseq:XP_011536148.1|refseq:XP_005253888.1|ensembl:ENSG00000139410(gene)|ensembl:ENST00000345635(transcript)|ensembl:ENST00000403593(transcript)|go:"GO:0003941"(L-serine ammonia-lyase activity)|go:"GO:0004794"(L-threonine ammonia-lyase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006567"(threonine catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000634(Serine/threonine dehydratase, pyridoxal-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR036052|rcsb pdb:2RKB|reactome:R-HSA-8849175 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:h/KXL0QQIvUmSrpZt/Kgg41l5Ck9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:2C89D3047FBBFD81|rigid:SQMqY81w3rdq0D+8phHUxZgbvFQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55040 uniprotkb:P36406 intact:EBI-744104|uniprotkb:B2RA31|ensembl:ENSP00000297596|ensembl:ENSP00000379497 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:gem_human(display_long)|uniprotkb:GTP-binding mitogen-induced T-cell protein(gene name synonym)|uniprotkb:RAS-like protein KIR(gene name synonym)|uniprotkb:GEM(gene name)|psi-mi:GEM(display_short)|uniprotkb:KIR(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351037|imex:IM-20259-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005252.1|refseq:NP_859053.1|ensembl:ENSG00000164949(gene)|ensembl:ENST00000297596(transcript)|ensembl:ENST00000396194(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0051233"(spindle midzone)|go:"GO:0051276"(chromosome organization)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|mint:P55040|rcsb pdb:2CJW|rcsb pdb:2G3Y|rcsb pdb:2HT6|dip:DIP-41587N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:CfyDTGeo+FEaEBd5/Tw6dDau7ys9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:B8AB7C896FD6B4A7|rigid:o/NjexZaxcAomAiDcIkgcNrkduI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14 uniprotkb:Q9UGJ1 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351049|imex:IM-20259-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:462D27E79771FCF7|rigid:A9hA5jCjRGqJIQFK006AbrRL8Ks false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UGJ1 uniprotkb:Q9UKJ5 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-741528|ensembl:ENSP00000263921|uniprotkb:B2R639 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:chic2_human(display_long)|uniprotkb:BrX-like translocated in leukemia(gene name synonym)|uniprotkb:CHIC2(gene name)|psi-mi:CHIC2(display_short)|uniprotkb:BTL(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351045|imex:IM-20259-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_036242.1|ensembl:ENSG00000109220(gene)|ensembl:ENST00000263921(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019383|interpro:IPR039735 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:pdPnbCymmDTe6+o8PTDcQT595nY9606 intact-crc:E152199AF4431818|rigid:YZwdDhPx/G5Ss+E7e6BmDUJbrfI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UGJ1 uniprotkb:P14373 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351053|imex:IM-20259-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 intact-crc:5F17FD9E0B40DFCC|rigid:XYzcFJ1DVvTfVHhZ1f59rBOKe4o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5JST6 uniprotkb:Q9UGJ1 intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351057|imex:IM-20259-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14 refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:EDA025B1AD1A84B7|rigid:ym92aHkXmiMjbfWyumi6odbnOdY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62310 uniprotkb:Q969L4 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 intact:EBI-373268|ensembl:ENSP00000319341 psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:lsm10_human(display_long)|uniprotkb:LSM10(gene name)|psi-mi:LSM10(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351069|imex:IM-20259-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N refseq:NP_116270.1|ensembl:ENSG00000181817(gene)|ensembl:ENST00000315732(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005683"(U7 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|rcsb pdb:6V4X|reactome:R-HSA-111367|reactome:R-HSA-73856|reactome:R-HSA-77588 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rogid:4ppK2+oa0v/jsg0A8/cbgcZs2g49606 intact-crc:D04786542113D94A|rigid:ruHwUQ9sQlULEh9OjA7OlADQB24 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N653 uniprotkb:Q9UGJ1 intact:EBI-2350056|uniprotkb:Q14776|uniprotkb:Q20WK0|ensembl:ENSP00000496779 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 psi-mi:lztr1_human(display_long)|uniprotkb:LZTR1(gene name)|psi-mi:LZTR1(display_short)|uniprotkb:TCFL2(gene name synonym) psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351061|imex:IM-20259-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006758.2|ensembl:ENSG00000099949(gene)|ensembl:ENST00000646124(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:fsROpiwl+i0q2x5zOPQzssw6QYE9606 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 intact-crc:26AEDFE92931CCBD|rigid:zmcpscywWaynm9yCntg03mKuTLg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UGJ1 uniprotkb:Q8TES7 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-2350063|uniprotkb:B5MEM5|uniprotkb:Q96IF6|uniprotkb:Q96MA8|uniprotkb:Q96JG4|ensembl:ENSP00000465132 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:fbf1_human(display_long)|uniprotkb:ALB(gene name synonym)|uniprotkb:Protein albatross(gene name synonym)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)|uniprotkb:KIAA1863(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351065|imex:IM-20259-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_001306122.1|ensembl:ENSG00000188878(gene)|ensembl:ENST00000586717(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043297"(apical junction assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|reactome:R-HSA-5620912 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:L3WrrMbCU9aCdYlXB4h9s/WVU2o9606 intact-crc:D8E1AB6EA981618C|rigid:spo3BY6305IR7WYf/SlQ3PLOq/s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92624 uniprotkb:P14770 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-1754109|intact:EBI-2350079|uniprotkb:Q14445|uniprotkb:Q92525|uniprotkb:Q8N1D1|ensembl:ENSP00000303942 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:gpix_human(display_long)|uniprotkb:GP9(gene name)|psi-mi:GP9(display_short)|uniprotkb:Glycoprotein 9(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351073|imex:IM-20259-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:XP_011511003.1|refseq:XP_011511004.1|refseq:NP_000165.1|ensembl:ENSG00000169704(gene)|ensembl:ENST00000307395(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007596"(blood coagulation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:P14770|rcsb pdb:3REZ|reactome:R-HSA-140837|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-9673221|refseq:XP_005247431.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:ZtxoUr0HvC9yHFE9HXSPRc20Zaw9606 intact-crc:FC5EF7DCDE570C52|rigid:lIKQPQMsqiNXGxJTN/FWgXCoVO4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96M61 uniprotkb:Q06547 intact:EBI-741835|ensembl:ENSP00000314543 intact:EBI-618165|ensembl:ENSP00000220429|uniprotkb:Q06545|uniprotkb:Q12940|uniprotkb:Q12941|uniprotkb:Q12942|uniprotkb:Q8IYD0|uniprotkb:A8IE52 psi-mi:magbi_human(display_long)|uniprotkb:MAGE-B18 antigen(gene name synonym)|uniprotkb:MAGEB18(gene name)|psi-mi:MAGEB18(display_short) psi-mi:gabp1_human(display_long)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351077|imex:IM-20259-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775970.1|ensembl:ENSG00000176774(gene)|ensembl:ENST00000325250(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|ensembl:ENSP00000314543 ensembl:ENSG00000104064(gene)|ensembl:ENST00000220429(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q06547|reactome:R-HSA-2151201|refseq:NP_002032.2|refseq:NP_005245.2|refseq:NP_057738.1|refseq:NP_057739.1|refseq:NP_852092.1|refseq:NP_001307839.1|refseq:XP_005254331.1|refseq:XP_016877542.1|dip:DIP-33979N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:eiI365GXPz0jCpm8/Oc1QscEDD09606 rogid:JO5HOl2ohh7LmNIn5UyYNbGviYE9606 intact-crc:416EC6D98A565546|rigid:xaCiANXO6WsWK8NbUpNvY1L3RJQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H0W9 uniprotkb:Q15645 intact:EBI-740204|uniprotkb:Q6FI88|uniprotkb:Q6XYB0|uniprotkb:Q96EI3|uniprotkb:Q96IX1|uniprotkb:Q9Y6B4|ensembl:ENSP00000346403|ensembl:ENSP00000435113|ensembl:ENSP00000331209|uniprotkb:A8K850 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ck054_human(display_long)|uniprotkb:C11orf54(gene name)|psi-mi:C11orf54(display_short)|uniprotkb:LP4947(orf name)|uniprotkb:PTD012(orf name) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351081|imex:IM-20259-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272996.1|refseq:NP_001272997.1|refseq:NP_001272998.1|refseq:NP_001272999.1|refseq:NP_001273000.1|refseq:NP_054758.2|ensembl:ENST00000331239(transcript)|ensembl:ENST00000354421(transcript)|ensembl:ENST00000528099(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015021(Region of unknown function DUF1907)|rcsb pdb:1XCR|ensembl:ENSG00000182919(gene)|refseq:XP_016873105.1|refseq:XP_011541083.1|refseq:XP_011541084.1|refseq:XP_006718887.1|refseq:XP_016873102.1|refseq:XP_016873103.1|refseq:XP_016873104.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+tNv81xp+nSoxhIbvT5MAYrZ+FY9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:5F0E58303DE311EA|rigid:3W+o68y9SFFYLhr3CWi3rOvXbjU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21266 uniprotkb:P21266 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351085|imex:IM-20259-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249 refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 intact-crc:C0442D35AD6355F3|rigid:EqAux5AHNCr/MkVeOk9dZRdDRpM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:P17482 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351093|imex:IM-20259-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:19FDCAB49F8C0975|rigid:ffBFWN4bPe4MINWhvDXOfHqP/24 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15654 uniprotkb:P31269 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 intact:EBI-742314|uniprotkb:O43369|uniprotkb:O43429|uniprotkb:Q99820|ensembl:ENSP00000343619 psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:hxa9_human(display_long)|uniprotkb:HOXA9(gene name)|psi-mi:HOXA9(display_short)|uniprotkb:HOX1G(gene name synonym)|uniprotkb:Homeobox protein Hox-1G(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351089|imex:IM-20259-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N refseq:NP_689952.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|ensembl:ENSG00000078399(gene)|ensembl:ENST00000343483(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rogid:04nr6zxW4HQtzJhTZNTajO6jmWY9606 intact-crc:35FB74F2F7C8744C|rigid:fv04ItSTaBaZaR+mRyswcg0ME0g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21673 uniprotkb:P17482 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351097|imex:IM-20259-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 intact-crc:CCE9C86462DA2626|rigid:BXElRzW3BNfp72dUfMMig/8g2ds false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29972 uniprotkb:Q6UY14 intact:EBI-745213|uniprotkb:Q8TBI5|uniprotkb:Q8TDC1|uniprotkb:B5BU39|ensembl:ENSP00000311165|ensembl:ENSP00000498672|uniprotkb:F5GY19|uniprotkb:E7EM69|uniprotkb:E9PC21 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 psi-mi:aqp1_human(display_long)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)|uniprotkb:Urine water channel(gene name synonym)|uniprotkb:AQP1(gene name)|psi-mi:AQP1(display_short)|uniprotkb:CHIP28(gene name synonym) psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351105|imex:IM-20259-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932766.1|ensembl:ENSG00000240583(gene)|ensembl:ENST00000311813(transcript)|ensembl:ENST00000652696(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|rcsb pdb:1FQY|rcsb pdb:1H6I|rcsb pdb:1IH5|rcsb pdb:4CSK|rcsb pdb:6POJ|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-29607N refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:0y0L/lmXZ68WhUSetgKRrSFdT1I9606 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 intact-crc:9D7E1FE7DEBC80BF|rigid:CZmv83gz6s+SRn3zGrw0gf/8qcc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29972 uniprotkb:Q99750 intact:EBI-745213|uniprotkb:Q8TBI5|uniprotkb:Q8TDC1|uniprotkb:B5BU39|ensembl:ENSP00000311165|ensembl:ENSP00000498672|uniprotkb:F5GY19|uniprotkb:E7EM69|uniprotkb:E9PC21 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:aqp1_human(display_long)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)|uniprotkb:Urine water channel(gene name synonym)|uniprotkb:AQP1(gene name)|psi-mi:AQP1(display_short)|uniprotkb:CHIP28(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351101|imex:IM-20259-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_932766.1|ensembl:ENSG00000240583(gene)|ensembl:ENST00000311813(transcript)|ensembl:ENST00000652696(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|rcsb pdb:1FQY|rcsb pdb:1H6I|rcsb pdb:1IH5|rcsb pdb:4CSK|rcsb pdb:6POJ|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-432040|reactome:R-HSA-432047|dip:DIP-29607N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:0y0L/lmXZ68WhUSetgKRrSFdT1I9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:90412F320A680589|rigid:vSDDKcLShwOLPH57V3bHjjpggBc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IUU6 uniprotkb:Q96MA1 intact:EBI-746574 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 psi-mi:q8iuu6_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short) psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351113|imex:IM-20259-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6UMK2pY5ytVRxzocsv5L27L5Y4c9606 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 intact-crc:A619E25ECBD6852B|rigid:5IvcDAKH8O6rBYV4GLgSK8j+ZVo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06547 uniprotkb:Q8IUU6 intact:EBI-618165|ensembl:ENSP00000220429|uniprotkb:Q06545|uniprotkb:Q12940|uniprotkb:Q12941|uniprotkb:Q12942|uniprotkb:Q8IYD0|uniprotkb:A8IE52 intact:EBI-746574 psi-mi:gabp1_human(display_long)|uniprotkb:GABP subunit beta-2(gene name synonym)|uniprotkb:Transcription factor E4TF1-53(gene name synonym)|uniprotkb:Transcription factor E4TF1-47(gene name synonym)|uniprotkb:Nuclear respiratory factor 2(gene name synonym)|uniprotkb:GABPB1(gene name)|psi-mi:GABPB1(display_short)|uniprotkb:E4TF1B(gene name synonym)|uniprotkb:GABPB(gene name synonym)|uniprotkb:GABPB2(gene name synonym) psi-mi:q8iuu6_human(display_long)|uniprotkb:IL16(gene name)|psi-mi:IL16(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351109|imex:IM-20259-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104064(gene)|ensembl:ENST00000220429(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q06547|reactome:R-HSA-2151201|refseq:NP_002032.2|refseq:NP_005245.2|refseq:NP_057738.1|refseq:NP_057739.1|refseq:NP_852092.1|refseq:NP_001307839.1|refseq:XP_005254331.1|refseq:XP_016877542.1|dip:DIP-33979N interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JO5HOl2ohh7LmNIn5UyYNbGviYE9606 rogid:6UMK2pY5ytVRxzocsv5L27L5Y4c9606 intact-crc:6B1D120F38BF827C|rigid:LpZ8VWoRMbp4gz+b4bvCQZOnaaQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q14847 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351121|imex:IM-20259-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 intact-crc:C6CDC0C2F3D37E8D|rigid:d8D3aBEKwZ1TL+zzUdxmUZWdEbg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:P55064 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-746103|uniprotkb:Q6FGW8|ensembl:ENSP00000293599 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:aqp5_human(display_long)|uniprotkb:AQP5(gene name)|psi-mi:AQP5(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351117|imex:IM-20259-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001642.1|ensembl:ENSG00000161798(gene)|ensembl:ENST00000293599(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0005902"(microvillus)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046541"(saliva secretion)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023276|interpro:IPR034294|rcsb pdb:3D9S|rcsb pdb:5C5X|rcsb pdb:5DYE|reactome:R-HSA-432047|dip:DIP-46292N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:YqO+Y0prbff02iGeHMUow4FcIRc9606 intact-crc:2312F498AF8A8BAC|rigid:sf998/lrdGdrE50CNHfwLSSGoy0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14847 uniprotkb:Q15645 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351125|imex:IM-20259-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:304960F3E89109DD|rigid:EH2HGAakeh0Gq1uo0pBpitqiOBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14847 uniprotkb:Q15038 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351129|imex:IM-20259-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:5E049B644E54CE34|rigid:qbODRqJs9/9admDJ+dPblBLCqis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75427 uniprotkb:Q99750 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351137|imex:IM-20259-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:26A327224AB35337|rigid:iCvWrkm+sYPB2PzGi5PtkGzkXfY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:P48059 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-306928|uniprotkb:Q53TE0|ensembl:ENSP00000331775|ensembl:ENSP00000376987|uniprotkb:Q9BS44|uniprotkb:B2RAJ4|uniprotkb:B7Z483|uniprotkb:B7Z7R3|uniprotkb:B7Z907 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:lims1_human(display_long)|uniprotkb:LIMS1(gene name)|psi-mi:LIMS1(display_short)|uniprotkb:Particularly interesting new Cys-His protein 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-48(gene name synonym)|uniprotkb:PINCH(gene name synonym)|uniprotkb:PINCH1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351133|imex:IM-20259-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 ensembl:ENSG00000169756(gene)|ensembl:ENST00000332345(transcript)|ensembl:ENST00000393310(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007569"(cell aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR017351(PINCH)|mint:P48059|rcsb pdb:1G47|rcsb pdb:1NYP|rcsb pdb:1U5S|rcsb pdb:2COR|rcsb pdb:2D8X|rcsb pdb:2KBX|rcsb pdb:3F6Q|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIF|rcsb pdb:7D2S|rcsb pdb:7D2T|rcsb pdb:7D2U|rcsb pdb:7LT9|reactome:R-HSA-446353|reactome:R-HSA-446388|refseq:NP_001180417.1|refseq:NP_004978.2|refseq:NP_001180411.1|refseq:NP_001180413.1|refseq:NP_001180414.1|refseq:NP_001180412.1|dip:DIP-40671N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:LzyCXdAH+qg5n0paw0Stf7+CK2w9606 intact-crc:091B28DE9E3EC844|rigid:IxRG/E4n4boa5Ukk1otVm1yV6ms false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q5T681 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744052|uniprotkb:Q49A70|uniprotkb:Q8N3Y6|ensembl:ENSP00000359674 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cj062_human(display_long)|uniprotkb:C10orf62(gene name)|psi-mi:C10orf62(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351141|imex:IM-20259-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001009997.2|ensembl:ENSG00000203942(gene)|ensembl:ENST00000370640(transcript)|interpro:IPR037649 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:UL8jisC+5EfnT+1B4SyTXUxQVlg9606 intact-crc:4371DA092CA7D234|rigid:kc/rtqDyAUBaZiidWEY+qSttrCI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40692 uniprotkb:O75152 intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym) psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351145|imex:IM-20259-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446 refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 intact-crc:1AA8D6DE9BAD70C6|rigid:QrpbSGZh99Bq1o25P7i8VZbnC9I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O95182 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351149|imex:IM-20259-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606 intact-crc:66F033E20D0404B9|rigid:RfabJbdTP6p2PKdqSn6NukEDiOc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23511 uniprotkb:Q92624 intact:EBI-389739|uniprotkb:Q8IXU0|ensembl:ENSP00000345702 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:nfya_human(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351153|imex:IM-20259-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002496.1|refseq:NP_068351.1|ensembl:ENSG00000001167(gene)|ensembl:ENST00000341376(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B)|interpro:IPR018362|rcsb pdb:4AWL|rcsb pdb:6QMP|rcsb pdb:6QMQ|rcsb pdb:6QMS|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ZzEyS17rD3653YFSvnBoGdl1T3s9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:679BA1495941DFD1|rigid:CxR3VDsOVUNAPPKD+VV8vOzQdPU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60260 uniprotkb:Q15645 intact:EBI-716346|uniprotkb:A3FG77|uniprotkb:Q5TFV8|uniprotkb:Q6Q2I6|uniprotkb:Q8NI41|uniprotkb:Q8NI43|uniprotkb:Q8NI44|uniprotkb:D3JZW7|uniprotkb:D3K2X0|uniprotkb:Q5VVX4|uniprotkb:Q8WW07|uniprotkb:A8K975|ensembl:ENSP00000355865 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:prkn_human(display_long)|uniprotkb:PRKN(gene name)|psi-mi:PRKN(display_short)|uniprotkb:PARK2(gene name synonym)|uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)|uniprotkb:Parkinson juvenile disease protein 2(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351157|imex:IM-20259-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004553.2|refseq:NP_054642.2|refseq:NP_054643.2|ensembl:ENSG00000185345(gene)|ensembl:ENST00000366898(transcript)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0098793"(presynapse)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902254"(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|mint:O60260|rcsb pdb:1IYF|rcsb pdb:2JMO|rcsb pdb:4BM9|rcsb pdb:4I1F|rcsb pdb:4I1H|rcsb pdb:5C1Z|rcsb pdb:5C23|rcsb pdb:5C9V|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5TR5|rcsb pdb:6GLC|rcsb pdb:6HUE|rcsb pdb:6N13|reactome:R-HSA-5205685|reactome:R-HSA-5689877|reactome:R-HSA-9646399|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001964"(startle response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032368"(regulation of lipid transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051582"(positive regulation of neurotransmitter uptake)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0097413"(Lewy body)|dip:DIP-37655N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:KbbW8SMJIWwQvR4lvsKyi25NRUw9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:B827F59152A357ED|rigid:xOYs9y00A8MghVFchHCvMKpXo3I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5TAQ9 uniprotkb:Q99750 intact:EBI-740686|uniprotkb:Q12839|uniprotkb:Q4QQI6|uniprotkb:Q53F14|uniprotkb:Q66K50|uniprotkb:Q68CS7|uniprotkb:Q96E00|intact:EBI-2559125|uniprotkb:D3DVE6|ensembl:ENSP00000318227|ensembl:ENSP00000357052|ensembl:ENSP00000357053 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dcaf8_human(display_long)|uniprotkb:DCAF8(gene name)|psi-mi:DCAF8(display_short)|uniprotkb:H326(gene name synonym)|uniprotkb:WDR42A(gene name synonym)|uniprotkb:WD repeat-containing protein 42A(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351161|imex:IM-20259-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056541.2|ensembl:ENSG00000132716(gene)|ensembl:ENST00000326837(transcript)|ensembl:ENST00000368073(transcript)|ensembl:ENST00000368074(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q5TAQ9|rcsb pdb:3I8E|reactome:R-HSA-8951664|dip:DIP-48762N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6Bbv6KwtHrJ0W4mcIronVPj4bTA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:F09C9FF620585AD1|rigid:4qmRZmk/qTtWc690EgBo7TdJphY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6RW13 uniprotkb:Q96AL5 intact:EBI-741181|ensembl:ENSP00000319713|uniprotkb:A8MVQ5|uniprotkb:Q5SNV4|uniprotkb:Q5SNV5|uniprotkb:Q96AC0|uniprotkb:Q96PL4|uniprotkb:Q9NRW9 intact:EBI-741171 psi-mi:atrap_human(display_long)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:ATRAP(gene name synonym) psi-mi:q96al5_human(display_long)|uniprotkb:PBX3(gene name)|psi-mi:PBX3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351169|imex:IM-20259-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035284.1|refseq:NP_001035285.1|refseq:NP_001035286.1|refseq:NP_001035287.1|refseq:NP_065083.3|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009436(Angiotensin II, type I receptor-associated)|mint:Q6RW13|reactome:R-HSA-6802952|ensembl:ENSG00000177674(gene)|ensembl:ENST00000314340(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus) interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR005542(PBX)|refseq:NP_006186.1|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:z+Us8VGLb+tlxNibfVodbuMZ6+89606 rogid:i9wU2k+DRdIptKLg9/LACfQiX0o9606 intact-crc:6597E062E20E74EF|rigid:RDCkNbJkG5spSCngbCRlRetTZPM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q96AL5 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-741171 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:q96al5_human(display_long)|uniprotkb:PBX3(gene name)|psi-mi:PBX3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351165|imex:IM-20259-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR005542(PBX)|refseq:NP_006186.1|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:i9wU2k+DRdIptKLg9/LACfQiX0o9606 intact-crc:345DBF8D070FE455|rigid:+6puSmjjKvWYnyieh8VEcG1n7y8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3B2 uniprotkb:Q9NQT4 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351173|imex:IM-20259-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 intact-crc:8B1182E48C05D50D|rigid:g4l1Xa47ej5OzCFmRa1UR7MkUek false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GX9 uniprotkb:Q96GX9 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351177|imex:IM-20259-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 intact-crc:9BE47E9CD1811CFA|rigid:a/+LJWdWTbqNg0idZjWaJeeBVac false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99816 uniprotkb:Q9UK41 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351181|imex:IM-20259-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:ED0AD49D4B1E0BFB|rigid:IPcqleypZ+xH6ZjayAZoSPsWZ4U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13049 uniprotkb:O76083 intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8 intact:EBI-742764|uniprotkb:O75490|uniprotkb:O75491|uniprotkb:O95225|uniprotkb:Q86SF7|uniprotkb:Q86SI6|uniprotkb:Q86SJ3|uniprotkb:Q86WN3|uniprotkb:Q86WN4|uniprotkb:Q86WN5|uniprotkb:Q86WN6|uniprotkb:Q86WN7|uniprotkb:Q86WN8|uniprotkb:Q86WN9|uniprotkb:Q86WP0|uniprotkb:B2RBI5|uniprotkb:Q53Y40|uniprotkb:B4DFI5|uniprotkb:Q5QD39|uniprotkb:D3DSJ8|uniprotkb:D3DSJ9|ensembl:ENSP00000291539 psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym) psi-mi:pde9a_human(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351189|imex:IM-20259-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1 rcsb pdb:3DYS|refseq:NP_001001567.1|refseq:NP_001001568.1|refseq:NP_001001569.1|refseq:NP_001001570.1|refseq:NP_001001571.1|refseq:NP_001001572.1|refseq:NP_001001573.1|refseq:NP_001001574.1|refseq:NP_001001575.1|refseq:NP_001001576.1|refseq:NP_001001577.1|refseq:NP_001001578.1|refseq:NP_001001579.1|refseq:NP_001001580.1|refseq:NP_001001581.1|refseq:NP_001001582.1|refseq:NP_001001583.1|refseq:NP_001001584.1|refseq:NP_001001585.1|refseq:NP_002597.1|refseq:NP_001302462.1|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0046068"(cGMP metabolic process)|go:"GO:0046069"(cGMP catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047555"(3',5'-cyclic-GMP phosphodiesterase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|ensembl:ENSG00000160191(gene)|ensembl:ENST00000291539(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0032587"(ruffle membrane)|interpro:IPR023174|interpro:IPR036971|mint:O76083|rcsb pdb:2HD1|rcsb pdb:2YY2|rcsb pdb:3DY8|rcsb pdb:3DYL|rcsb pdb:3DYN|rcsb pdb:3DYQ|rcsb pdb:3JSW|rcsb pdb:3K3E|rcsb pdb:3K3H|rcsb pdb:3N3Z|rcsb pdb:3QI3|rcsb pdb:3QI4|rcsb pdb:4E90|rcsb pdb:4G2J|rcsb pdb:4G2L|rcsb pdb:4GH6|rcsb pdb:4Y86|rcsb pdb:4Y87|rcsb pdb:4Y8C|rcsb pdb:6A3N|rcsb pdb:6LZZ|reactome:R-HSA-418457|rcsb pdb:3JSI|refseq:XP_016883855.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606 rogid:ihS9g9TSkHsEA4olMOO+krgypow9606 intact-crc:0F11BC15895B9E1E|rigid:POOKDODWO1M5AqOfEbR3K/PjifU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P2T0 uniprotkb:Q99750 intact:EBI-751020|uniprotkb:A6NMJ8|ensembl:ENSP00000340088 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:theg_human(display_long)|uniprotkb:Cancer/testis antigen 56(gene name synonym)|uniprotkb:THEG(gene name)|psi-mi:THEG(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351185|imex:IM-20259-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057669.1|refseq:NP_954672.1|ensembl:ENSG00000105549(gene)|ensembl:ENST00000342640(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR006623(Testicular haploid expressed repeat)|interpro:IPR042401 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PZ1WgUhnuF1kU16FsiZlJwqS8QE9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:4AC9B3D7BFCB2187|rigid:rQZUrWfgUaLM98r8oIbpecknzvI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:Q9NS73 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351197|imex:IM-20259-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:00B662CE323FB621|rigid:FnF/rpb5E9sPkpqXuWSdD0GfNts false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UH62 uniprotkb:Q9H063 intact:EBI-717832|uniprotkb:Q53HC6|uniprotkb:Q7LCF5|uniprotkb:Q9NPE4|ensembl:ENSP00000340672|ensembl:ENSP00000439032|ensembl:ENSP00000454483 intact:EBI-720354|uniprotkb:D3DWL4|ensembl:ENSP00000318604|ensembl:ENSP00000436720 psi-mi:armx3_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 3(gene name synonym)|uniprotkb:ARMCX3(gene name)|psi-mi:ARMCX3(display_short)|uniprotkb:ALEX3(gene name synonym)|uniprotkb:BM-017(orf name)|uniprotkb:UNQ2517/PRO6007(orf name) psi-mi:maf1_human(display_long)|uniprotkb:MAF1(gene name)|psi-mi:MAF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351201|imex:IM-20259-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057691.1|refseq:NP_808816.1|refseq:NP_808817.1|refseq:XP_005262198.1|ensembl:ENSG00000102401(gene)|ensembl:ENST00000341189(transcript)|ensembl:ENST00000471229(transcript)|ensembl:ENST00000537169(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-9013404 refseq:NP_115648.2|ensembl:ENST00000532522(transcript)|go:"GO:0000994"(RNA polymerase III core binding)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENST00000322428(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060077"(inhibitory synapse)|interpro:IPR015257(Maf1 regulator)|interpro:IPR038564|rcsb pdb:3NR5|reactome:R-HSA-8943724|go:"GO:0050811"(GABA receptor binding)|ensembl:ENSG00000179632(gene)|refseq:XP_016869393.1|dip:DIP-53028N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Svmu819cxCJThLvYapRMLQpAszw9606 rogid:oendhtb8R+yuFDCrOhSxk8kRrVI9606 intact-crc:467E69F50FB9F293|rigid:kLXrsxbsJYKbAS6v4T+kKqWqVZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01127 uniprotkb:Q99750 intact:EBI-1554925|uniprotkb:P78431|uniprotkb:Q9UF23|uniprotkb:G3XAG8|uniprotkb:Q15354|uniprotkb:Q6FHE7|ensembl:ENSP00000330382 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pdgfb_human(display_long)|uniprotkb:Platelet-derived growth factor B chain(gene name synonym)|uniprotkb:Platelet-derived growth factor beta polypeptide(gene name synonym)|uniprotkb:PDGF-2(gene name synonym)|uniprotkb:Proto-oncogene c-Sis(gene name synonym)|uniprotkb:PDGFB(gene name)|psi-mi:PDGFB(display_short)|uniprotkb:PDGF2(gene name synonym)|uniprotkb:SIS(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351193|imex:IM-20259-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002599.1|refseq:NP_148937.1|dip:DIP-5737N|ensembl:ENSG00000100311(gene)|ensembl:ENST00000331163(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035793"(positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0038001"(paracrine signaling)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071506"(cellular response to mycophenolic acid)|go:"GO:0072126"(positive regulation of glomerular mesangial cell proliferation)|go:"GO:0072255"(metanephric glomerular mesangial cell development)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905176"(positive regulation of vascular associated smooth muscle cell dedifferentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000591"(positive regulation of metanephric mesenchymal cell migration)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR006782(Platelet-derived growth factor, N-terminal)|interpro:IPR015583(Platelet-Derived Growth Factor B Chain)|interpro:IPR023581|interpro:IPR029034|rcsb pdb:1PDG|rcsb pdb:3MJG|rcsb pdb:4HQU|rcsb pdb:4HQX|rcsb pdb:4QCI|rcsb pdb:6T9E|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-186763|reactome:R-HSA-186797|reactome:R-HSA-2219530|reactome:R-HSA-3000171|reactome:R-HSA-5673001|reactome:R-HSA-6811558 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:6zBbnXOTaM6thsuAbXfQoHHZ/EA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:DA00C7F01BAED9A9|rigid:LonZa4T01KXnCHi/KMiR3Thdn5w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H0E2 uniprotkb:Q15038 intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short) psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351205|imex:IM-20259-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 intact-crc:19D90D69F78F62C9|rigid:i5423jFYW5U/NCFw8dk2iIoSCqk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17028 uniprotkb:Q9NX65 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 intact:EBI-739949|ensembl:ENSP00000380061|uniprotkb:Q6WMU8|uniprotkb:Q7Z6G2|uniprotkb:Q8NFX8|uniprotkb:Q9BU74|uniprotkb:B4DWL5|uniprotkb:C9JB03 psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:zsc32_human(display_long)|uniprotkb:ZNF434(gene name synonym)|uniprotkb:ZSCAN32(gene name)|psi-mi:ZSCAN32(display_short)|uniprotkb:Human cervical cancer suppressor gene 5 protein(gene name synonym)|uniprotkb:Zinc finger protein 434(gene name synonym)|uniprotkb:HCCS5(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351209|imex:IM-20259-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR refseq:NP_001271456.1|refseq:NP_001271457.1|refseq:NP_001271458.1|ensembl:ENSG00000140987(gene)|ensembl:ENST00000396852(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|interpro:IPR044822|reactome:R-HSA-212436|refseq:NP_060280.2|refseq:NP_001311269.1|refseq:NP_001311270.1|refseq:NP_001311271.1|refseq:NP_001311273.1|refseq:NP_001311274.1|refseq:XP_011520857.1|refseq:XP_016878860.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rogid:47ThjrCJntK2wDE5Iop8KGAmVYQ9606 intact-crc:B241806D7309590D|rigid:sGZOJJc3ZY+v6INXgeeRr04caGE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q8N9H8 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-750745|uniprotkb:Q6P1M1|uniprotkb:Q8IXT8|uniprotkb:A0A140VJP9|uniprotkb:B8A4U7|uniprotkb:C9JIQ9|uniprotkb:E9PN82|uniprotkb:Q2TAK4|uniprotkb:Q8N3X4|uniprotkb:Q8NHD1|uniprotkb:Q96NP1|uniprotkb:Q9NX53|ensembl:ENSP00000340474 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:mut7_human(display_long)|uniprotkb:EXD3(gene name)|psi-mi:EXD3(display_short)|uniprotkb:Exonuclease 3'-5' domain-containing protein 3(gene name synonym)|uniprotkb:HBE269(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351213|imex:IM-20259-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_001273752.1|refseq:NP_060290.3|ensembl:ENSG00000187609(gene)|ensembl:ENST00000340951(transcript)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR002782(Protein of unknown function DUF82)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR037432|go:"GO:0003676"(nucleic acid binding) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:uBnG+EqGieSQ9G+7oh0Kdd2QuLU9606 intact-crc:4EE803A609D16EE8|rigid:nG3g4cRL91/Noqxdq2ngnC/U3bQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96EN9 uniprotkb:Q99750 intact:EBI-745810|uniprotkb:Q8NAX4|uniprotkb:Q9NWI0|ensembl:ENSP00000351422|intact:EBI-11084128|uniprotkb:E9PAS0 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:rex1b_human(display_long)|uniprotkb:REX1BD(gene name)|psi-mi:REX1BD(display_short)|uniprotkb:C19orf60(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351217|imex:IM-20259-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001093888.1|refseq:NP_001093889.1|ensembl:ENSG00000006015(gene)|ensembl:ENST00000358607(transcript)|interpro:IPR039491 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:y/YOKlXvG7PSR+fFGaenSTvgxO09606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:0E2DF4AA93862F7E|rigid:nEJ8Ijo2sNDKyEl3fB6Z/0+G738 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q96HA8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351221|imex:IM-20259-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:B42B1384E94146F5|rigid:gxrpq7UZ4gIw1dABQ/QFkJg7Oq4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00492 uniprotkb:Q96HA8 intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351225|imex:IM-20259-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:955A71CD98DA852E|rigid:mWUnpuF9r51/wArignTkCnp79rE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14923 uniprotkb:Q96HA8 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351229|imex:IM-20259-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:83D3EFDC4DACD9E8|rigid:o1qFsMUgaiSCI5pYfmRD/TMEANQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96HA8 uniprotkb:P15531 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351233|imex:IM-20259-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:B8F971ADED4DAD20|rigid:Ev6J3CH9sB+ovO4ubnpabzQfqh8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96HA8 uniprotkb:Q9BPX1 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351237|imex:IM-20259-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 intact-crc:BB03E7D3294E1417|rigid:JLkgRQATLmyge3rE6mGX/uMIImc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03393 uniprotkb:Q96HA8 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351241|imex:IM-20259-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 intact-crc:58D40AD4F7D1B935|rigid:yXNtuzKAjjfLVUe/OT6kGh7zw6Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96HA8 uniprotkb:Q15645 intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351245|imex:IM-20259-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:F1BDB2B0CD95D237|rigid:C9dMo4hA1Eu0byyoMhDgGXs7QBk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7L2Z9 uniprotkb:Q0VDD7 intact:EBI-2350265|uniprotkb:Q6IN61|uniprotkb:Q9NVS5|uniprotkb:A8KAF1|ensembl:ENSP00000337289 intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49 psi-mi:cenpq_human(display_long)|uniprotkb:CENPQ(gene name)|psi-mi:CENPQ(display_short)|uniprotkb:C6orf139(gene name synonym) psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351253|imex:IM-20259-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060602.2|refseq:XP_005249262.1|ensembl:ENSG00000031691(gene)|ensembl:ENST00000335783(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051310"(metaphase plate congression)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR025212|mint:Q7L2Z9|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:qSVZT9uWH/55f1YtdJrC7U90clk9606 rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606 intact-crc:F04794534D816B1C|rigid:B/qAaYkItuYS9mp8RbLpuHRXvwE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P67775 uniprotkb:Q15645 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351249|imex:IM-20259-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:EB34C35924C33A0B|rigid:dQ41Om7CQlVlLMmXSMZbK2qeBxQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:Q9C0A6 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-745351|uniprotkb:Q6AI17|uniprotkb:Q8WUB6|uniprotkb:Q9H3X4|uniprotkb:Q9H6V7|uniprotkb:Q9H7S3|uniprotkb:Q9NVI9|ensembl:ENSP00000383939|ensembl:ENSP00000385852 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:setd5_human(display_long)|uniprotkb:SETD5(gene name)|psi-mi:SETD5(display_short)|uniprotkb:KIAA1757(gene name synonym)|uniprotkb:SET domain-containing protein 5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351257|imex:IM-20259-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_001073986.1|ensembl:ENSG00000168137(gene)|ensembl:ENST00000402198(transcript)|ensembl:ENST00000406341(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0050890"(cognition)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR001214(SET)|interpro:IPR044433|ensembl:ENSP00000385852|ensembl:ENSP00000383939|refseq:NP_001278972.1|refseq:XP_016862270.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:kuNqd2aC46saPlIZrVY0+CIJsRg9606 intact-crc:7B421CD55FECF571|rigid:e0NAYJSG643wR9dT7zF3LhCujk8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NVF9 uniprotkb:Q99750 intact:EBI-751864|uniprotkb:B7Z7K1|uniprotkb:Q5SXX5|uniprotkb:Q68CK3|uniprotkb:Q96G05|ensembl:ENSP00000356170 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:eki2_human(display_long)|uniprotkb:ETNK2(gene name)|psi-mi:ETNK2(display_short)|uniprotkb:EKI2(gene name synonym)|uniprotkb:Ethanolamine kinase-like protein(gene name synonym)|uniprotkb:HMFT1716(orf name) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351261|imex:IM-20259-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060678.2|refseq:NP_001284689.1|refseq:NP_001284690.1|refseq:NP_001284691.1|ensembl:ENSG00000143845(gene)|ensembl:ENST00000367202(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0004305"(ethanolamine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0035264"(multicellular organism growth)|interpro:IPR011009(Protein kinase-like)|reactome:R-HSA-1483213 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:aZ+GrsqSpVjuyjNe6KyQA6h5QEg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:2336FBD03100070F|rigid:vu3tj2FwY0wTOY202ZcvlhEy6c4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95273 uniprotkb:Q9NV31 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-747481|uniprotkb:Q53G10|uniprotkb:B3KQ67|ensembl:ENSP00000326981|ensembl:ENSP00000385217 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:imp3_human(display_long)|uniprotkb:BRMS2(gene name synonym)|uniprotkb:IMP3(gene name)|psi-mi:IMP3(display_short)|uniprotkb:C15orf12(gene name synonym)|uniprotkb:MRPS4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351265|imex:IM-20259-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 refseq:NP_060755.1|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR022801|interpro:IPR036986|mint:Q9NV31|rcsb pdb:2CQJ|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0030515"(snoRNA binding)|ensembl:ENSG00000177971(gene)|ensembl:ENST00000314852(transcript)|ensembl:ENST00000403490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:7tf5HEal59lCqBIvQaFLksqchAw9606 intact-crc:F057F907AE736D9B|rigid:JjgrElmuTVWdN0QS9WxvN+kA5kE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HB75 uniprotkb:Q99750 intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351269|imex:IM-20259-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:8FE53DB3EE0664E5|rigid:jKZl4jOHrhZ+DDgx4ybpOoaGBfg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKK6 uniprotkb:Q9H4D5 intact:EBI-301889|ensembl:ENSP00000254998 intact:EBI-750038|uniprotkb:Q9H1A9|uniprotkb:B4DYS7|uniprotkb:Q5H9I1|ensembl:ENSP00000378504 psi-mi:nxt1_human(display_long)|uniprotkb:NXT1(gene name)|psi-mi:NXT1(display_short)|uniprotkb:Protein p15(gene name synonym) psi-mi:nxf3_human(display_long)|uniprotkb:TAP-like protein 3(gene name synonym)|uniprotkb:NXF3(gene name)|psi-mi:NXF3(display_short)|uniprotkb:TAPL3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351273|imex:IM-20259-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132661(gene)|ensembl:ENST00000254998(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031267"(small GTPase binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|mint:Q9UKK6|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159236|refseq:NP_037380.1|refseq:XP_011527532.1|dip:DIP-33075N refseq:NP_071335.1|ensembl:ENSG00000147206(gene)|ensembl:ENST00000395065(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042272"(nuclear RNA export factor complex)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030216|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9H4D5 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PDP0uZzdRV3AfYiKREIBMCI1MBU9606 rogid:v0ff9hsaVYCa15gHW2PGhUDA8zY9606 intact-crc:5A56F52B34D38804|rigid:I1CSQbcXfXxw7n+7l/sGP2JhgJ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45984 uniprotkb:P32121 intact:EBI-713568|uniprotkb:Q15708|uniprotkb:Q15710|uniprotkb:Q15711|uniprotkb:Q8N5C5|uniprotkb:A8K0S3|ensembl:ENSP00000394560|uniprotkb:B5M0B4|uniprotkb:B5BU66|uniprotkb:D3DWQ8|uniprotkb:D3DWQ9 intact:EBI-714559|uniprotkb:Q0Z8D3|uniprotkb:Q2PP19|uniprotkb:Q6ICT3|uniprotkb:Q8N7Y2|uniprotkb:Q9UEQ6|uniprotkb:B7WPL3|uniprotkb:B5B0C0|uniprotkb:D3DTK2|intact:EBI-28974065|ensembl:ENSP00000269260|uniprotkb:B4DLW0|uniprotkb:H0Y688 psi-mi:mk09_human(display_long)|uniprotkb:Stress-activated protein kinase JNK2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 2(gene name synonym)|uniprotkb:JNK-55(gene name synonym)|uniprotkb:MAPK9(gene name)|psi-mi:MAPK9(display_short)|uniprotkb:JNK2(gene name synonym)|uniprotkb:PRKM9(gene name synonym)|uniprotkb:Stress-activated protein kinase 1a(gene name synonym)|uniprotkb:SAPK1A(gene name synonym) psi-mi:arrb2_human(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:ARRB2(gene name)|psi-mi:ARRB2(display_short)|uniprotkb:ARB2(gene name synonym)|uniprotkb:ARR2(gene name synonym)|uniprotkb:Non-visual arrestin-3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351277|imex:IM-20259-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006714954.1|refseq:NP_001128516.1|refseq:NP_002743.3|refseq:NP_620707.1|ensembl:ENSG00000050748(gene)|ensembl:ENST00000452135(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|refseq:NP_620708.1|refseq:NP_620709.1|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P45984|rcsb pdb:3E7O|rcsb pdb:3NPC|rcsb pdb:7CML|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-450341|refseq:NP_001295173.1|dip:DIP-270N|refseq:XP_016865127.1|refseq:XP_016865130.1 ensembl:ENSP00000269260|ensembl:ENST00000346341|ensembl:ENSP00000341895|ensembl:ENST00000381488|ensembl:ENSP00000370898|ensembl:ENST00000412477|ensembl:ENSP00000403701|ensembl:ENSG00000141480(gene)|ensembl:ENST00000269260(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR017864|go:"GO:0005634"(nucleus)|mint:P32121|reactome:R-HSA-2122948|reactome:R-HSA-418555|reactome:R-HSA-456926|reactome:R-HSA-5099900|reactome:R-HSA-5635838|reactome:R-HSA-5674135|reactome:R-HSA-5689880|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0005886"(plasma membrane)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:0007212"(dopamine receptor signaling pathway)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|go:"GO:0007420"(brain development)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007628"(adult walking behavior)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|refseq:NP_004304.1|refseq:NP_945355.1|refseq:NP_001316993.1|refseq:NP_001244259.1|refseq:NP_001244260.1|refseq:NP_001244257.1|refseq:NP_001244258.1|dip:DIP-40089N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ljhZd5mc0kj5al142zo5Me2J26w9606 rogid:MY34flMH9cdhPtMLGYOQtoQyr2U9606 intact-crc:067958272BEF84E4|rigid:KH01spl+0hROWjRBvBpY8gbeoMY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NR22 uniprotkb:Q9NR22 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 intact:EBI-745545|uniprotkb:Q8TBJ8|uniprotkb:B2RDP0|ensembl:ENSP00000372067 psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:anm8_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)|uniprotkb:PRMT8(gene name)|psi-mi:PRMT8(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:HRMT1L4(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351281|imex:IM-20259-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 refseq:NP_062828.3|mint:Q9NR22|rcsb pdb:4X41|rcsb pdb:5DST|interpro:IPR029063|ensembl:ENSG00000111218(gene)|ensembl:ENST00000382622(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|refseq:NP_001243465.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 rogid:7uf8Q0UFg4FIdFbCpFA+I09XiJc9606 intact-crc:5D7D997F9167CAE8|rigid:4EM8YY1nmBLwantqup/ZsLsog1s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P14324 uniprotkb:Q9NRA8 intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351285|imex:IM-20259-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 intact-crc:3BEB58EA6D2F497B|rigid:BWMZuP9vLAUPk9d4pAgfGERj5eM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:P25786 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351293|imex:IM-20259-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:49C3D1B0F74AC057|rigid:zearIaQCmkRKaXIClugj4vy/COU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25786 uniprotkb:Q5JR59 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 intact:EBI-742948|ensembl:ENSP00000483729|uniprotkb:O94872|uniprotkb:Q08E97|uniprotkb:Q5JQR3|uniprotkb:Q8N5E2|uniprotkb:B4DF81|uniprotkb:A7E292 psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:mtus2_human(display_long)|uniprotkb:TIP150(gene name synonym)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351289|imex:IM-20259-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N refseq:NP_001028774.2|refseq:NP_056048.1|ensembl:ENSG00000132938(gene)|ensembl:ENST00000612955(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR033339|mint:Q5JR59|ensembl:ENST00000380808|ensembl:ENSP00000370186|ensembl:ENST00000542829|ensembl:ENSP00000445403|ensembl:ENSP00000483729 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rogid:mC6V+TBEtOpFLeNXq09unF0p6N49606 intact-crc:CAC6EBA0C4288733|rigid:949pKe1qtyVXemNyfFpQpEsOSko false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95073 uniprotkb:P25786 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351297|imex:IM-20259-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:CA9C369FA11A2E86|rigid:Pyhni460ZrhWF+l5Ghut+YfBF3A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P25786 uniprotkb:P36406 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351301|imex:IM-20259-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:B3921F2DF13DF591|rigid:0gLfimvvCRNzEoYV0FP14yKmEKM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62191 uniprotkb:Q13200 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351309|imex:IM-20259-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:C19C375196605474|rigid:kENZn4mpZxbg8X5MvSIoEfoILDg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BPX1 uniprotkb:P25786 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351305|imex:IM-20259-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:1D391521661F2523|rigid:kPwkQX85M7xtALb2KlIIOLJhm0Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q9NR21 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-748917|uniprotkb:Q68DS1|uniprotkb:Q8N5Y9|uniprotkb:B4DRQ0|ensembl:ENSP00000228820|uniprotkb:F8WBZ7 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:par11_human(display_long)|uniprotkb:PARP11(gene name)|psi-mi:PARP11(display_short)|uniprotkb:C12orf6(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 11(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 11(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351313|imex:IM-20259-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001273450.1|refseq:NP_001273451.1|refseq:NP_065100.2|refseq:XP_005253768.1|refseq:XP_011519272.1|refseq:XP_011519273.1|refseq:XP_011519275.1|refseq:XP_016875159.1|refseq:XP_016875160.1|ensembl:ENSG00000111224(gene)|ensembl:ENST00000228820(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0030154"(cell differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR037197|rcsb pdb:2DK6 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2018/04/06 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:Trx2/F5euYxQbxo7rGNbvIKCnq89606 intact-crc:650A1BC15ED34D7D|rigid:qaYTuwo7kANlSUwa85PL4szE8m0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:Q9H8E8 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-750907|uniprotkb:Q96GW6|uniprotkb:Q96IH3|uniprotkb:Q9HBF0|uniprotkb:Q9UIY5|uniprotkb:A2A2I5|ensembl:ENSP00000366909|ensembl:ENSP00000392318|ensembl:ENSP00000424752|ensembl:ENSP00000503109|ensembl:ENSP00000503493|ensembl:ENSP00000504050|ensembl:ENSP00000504276 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:csr2b_human(display_long)|uniprotkb:KAT14(gene name)|psi-mi:KAT14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:CSRP2BP(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351317|imex:IM-20259-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_065397.3|ensembl:ENSG00000149474(gene)|ensembl:ENST00000377681(transcript)|ensembl:ENST00000435364(transcript)|ensembl:ENST00000464792(transcript)|ensembl:ENST00000676935(transcript)|ensembl:ENST00000677174(transcript)|ensembl:ENST00000677266(transcript)|ensembl:ENST00000678772(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030274"(LIM domain binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:Q9H8E8|reactome:R-HSA-3214847 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:/Udl5yqzzDQ9jsscSVJlzcGd/VI9606 intact-crc:627858D9E00DEC54|rigid:NUm8iw08DPcuprbcuiLbSIKaYEY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96AQ6 uniprotkb:Q99750 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351321|imex:IM-20259-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:F507C1EF74734F8E|rigid:a6AFXwZncdqipx2gHfCF+H6y1Ac false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3C0 uniprotkb:Q96AQ6 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351325|imex:IM-20259-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 intact-crc:B4888048BAEF8592|rigid:42Xovt5gGEd8QBeI+P6kzdoXvKs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99933 uniprotkb:P36406 intact:EBI-1030678|uniprotkb:O75315|uniprotkb:Q14414|uniprotkb:Q96TG2|uniprotkb:Q9Y2V4|uniprotkb:Q53H32|uniprotkb:Q5VZE8|uniprotkb:Q5VZE9|uniprotkb:Q5VZF0|ensembl:ENSP00000489189 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:bag1_human(display_long)|uniprotkb:BAG1(gene name)|psi-mi:BAG1(display_short)|uniprotkb:Bcl-2-associated athanogene 1(gene name synonym)|uniprotkb:HAP(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351329|imex:IM-20259-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001165886.1|refseq:NP_004314.5|ensembl:ENSG00000107262(gene)|ensembl:ENST00000634734(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|interpro:IPR017093(Molecular chaperone regulator BAG-1)|interpro:IPR029071|interpro:IPR036533|interpro:IPR039773|mint:Q99933|rcsb pdb:1HX1|rcsb pdb:1WXV|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|reactome:R-HSA-3371453|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|dip:DIP-3341N refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:wDyAGECTy45td5tL4mnwa1txPO49606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:A62326C6B1872171|rigid:h42u7fG0R9naCG3eRiJtp/nB6PI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P9B6 uniprotkb:Q15645 intact:EBI-746504|uniprotkb:Q9HCG3|uniprotkb:Q9NTE8|uniprotkb:Q8IZ64|ensembl:ENSP00000343635 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:meak7_human(display_long)|uniprotkb:MEAK7(gene name)|psi-mi:MEAK7(display_short)|uniprotkb:KIAA1609(gene name synonym)|uniprotkb:MTOR associated protein, eak-7 homolog(gene name synonym)|uniprotkb:TBC/LysM-associated domain-containing protein 1(gene name synonym)|uniprotkb:TLD domain-containing protein 1(gene name synonym)|uniprotkb:TLDC1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351333|imex:IM-20259-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011521550.1|refseq:XP_011521551.1|refseq:NP_065998.3|ensembl:ENSG00000140950(gene)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0032868"(response to insulin)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043200"(response to amino acid)|go:"GO:0150032"(positive regulation of protein localization to lysosome)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|interpro:IPR006571(TLDc)|ensembl:ENST00000343629(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|refseq:XP_006721303.1|refseq:XP_005256132.1|refseq:XP_016878999.1|refseq:XP_016879000.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:LDRPOUvJCNZ5eDPvjhfMoNFx98k9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:1C33E7A1DF3699C1|rigid:K4HCMtFpMG6sr1Lz0pb/7/Xew8A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16611 uniprotkb:Q07817 intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7 intact:EBI-78035|intact:EBI-28978054|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|uniprotkb:Q5TE65|uniprotkb:Q92976|uniprotkb:Q5CZ89|uniprotkb:E1P5L6 psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym) psi-mi:b2cl1_human(display_long)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351337|imex:IM-20259-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N refseq:NP_001182.1|refseq:NP_612815.1|ensembl:ENSG00000171552(gene)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript)|ensembl:ENST00000678563(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034097"(response to cytokine)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071839"(apoptotic process in bone marrow cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013279(Apoptosis regulator, Bcl-X)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|mint:Q07817|rcsb pdb:1BXL|rcsb pdb:1G5J|rcsb pdb:1LXL|rcsb pdb:1MAZ|rcsb pdb:1R2D|rcsb pdb:1R2E|rcsb pdb:1R2G|rcsb pdb:1R2H|rcsb pdb:1R2I|rcsb pdb:1YSG|rcsb pdb:1YSI|rcsb pdb:1YSN|rcsb pdb:2B48|rcsb pdb:2LP8|rcsb pdb:2LPC|rcsb pdb:2M03|rcsb pdb:2M04|rcsb pdb:2ME8|rcsb pdb:2ME9|rcsb pdb:2MEJ|rcsb pdb:2O1Y|rcsb pdb:2O2M|rcsb pdb:2O2N|rcsb pdb:2P1L|rcsb pdb:2PON|rcsb pdb:2YJ1|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:2YXJ|rcsb pdb:3CVA|rcsb pdb:3FDL|rcsb pdb:3FDM|rcsb pdb:3INQ|rcsb pdb:3IO8|rcsb pdb:3PL7|rcsb pdb:3QKD|rcsb pdb:3R85|rcsb pdb:6IJQ|rcsb pdb:6LHD|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:6RNU|rcsb pdb:6ST2|rcsb pdb:6UVC|rcsb pdb:6UVD|rcsb pdb:6UVE|rcsb pdb:6UVF|rcsb pdb:6UVG|rcsb pdb:6UVH|rcsb pdb:6VWC|rcsb pdb:6X7I|rcsb pdb:6YLI|rcsb pdb:6ZHC|rcsb pdb:7CA4|rcsb pdb:7JGV|rcsb pdb:7JGW|rcsb pdb:7LH7|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9648002|reactome:R-HSA-9702518|rcsb pdb:3SP7|rcsb pdb:3SPF|rcsb pdb:3WIZ|rcsb pdb:3ZK6|rcsb pdb:3ZLN|rcsb pdb:6F46|rcsb pdb:6HJL|rcsb pdb:3ZLO|rcsb pdb:3ZLR|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4AQ3|rcsb pdb:4BPK|rcsb pdb:4C52|rcsb pdb:4C5D|rcsb pdb:4CIN|rcsb pdb:4EHR|rcsb pdb:4HNJ|rcsb pdb:4IEH|rcsb pdb:4PPI|rcsb pdb:4QVE|rcsb pdb:4QVF|rcsb pdb:4QVX|rcsb pdb:4TUH|rcsb pdb:4Z9V|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5B1Z|rcsb pdb:5C3G|rcsb pdb:5FMJ|rcsb pdb:5FMK|rcsb pdb:5VAY|rcsb pdb:5VX3|rcsb pdb:6BF2|rcsb pdb:6DCN|rcsb pdb:6DCO|ensembl:ENSP00000365223|ensembl:ENSP00000365230|ensembl:ENSP00000390760|ensembl:ENST00000376055|ensembl:ENST00000422920|ensembl:ENSP00000411252|ensembl:ENSP00000401173|ensembl:ENSP00000389688|ensembl:ENSP00000395545|ensembl:ENSP00000503725|ensembl:ENSP00000504536|ensembl:ENSP00000504387|ensembl:ENSP00000504237|ensembl:ENSP00000302564|refseq:NP_001304848.1|refseq:NP_001304849.1|refseq:NP_001304850.1|refseq:NP_001309168.1|refseq:NP_001309169.1|refseq:NP_001309171.1|refseq:XP_011527266.1|refseq:XP_016883482.1|dip:DIP-30916N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 intact-crc:2A2C3017B1F0201C|rigid:Vsl19lBLoL75CYE+wO3EE44R3hE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:P49366 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351349|imex:IM-20259-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 intact-crc:2D352C6123ACD496|rigid:U48noGVWrygIsH2Wjr8mPUJIqvA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q9GZT8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351341|imex:IM-20259-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:0ABAE0C1818B6C3C|rigid:xLCziLZY57zjL1HktSyJiBc/PZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:P22234 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351345|imex:IM-20259-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 intact-crc:0463C510ABA662BC|rigid:zQJJP9eFy6Bu/2a7SinUWKOIxUk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:Q8N7W2 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351353|imex:IM-20259-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:6205FFD030F5FE6D|rigid:tSBFf8Ec+v26QGvGipL0Muc+VRM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95073 uniprotkb:Q9GZT8 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351357|imex:IM-20259-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:2E484A1829ADBCC7|rigid:z4cZ+fC8JcYdD6L91AkS5+xODaU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:P21673 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351369|imex:IM-20259-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:B769F102CEC36B33|rigid:5J9dwKGw7Z5heQ4E9p8swwUXTL0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GX9 uniprotkb:Q9GZT8 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351365|imex:IM-20259-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:F54A89EB6CB5EAB4|rigid:2vwrnGdWneli5PTwiZCbvJubIFI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:P15531 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351361|imex:IM-20259-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:34FFE3DFA4DA819F|rigid:/a2WG0Sz6ZG7ov9ACC4BDNDtuwY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MA1 uniprotkb:Q9GZT8 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351373|imex:IM-20259-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 intact-crc:240AC70E0F1A089F|rigid:jGKRILpYm0WQCY/nbpOY2UY56MY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62854 uniprotkb:Q969E8 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 intact:EBI-746981|ensembl:ENSP00000364293 psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:tsr2_human(display_long)|uniprotkb:TSR2(gene name)|psi-mi:TSR2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351381|imex:IM-20259-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 refseq:NP_477511.1|ensembl:ENSG00000158526(gene)|ensembl:ENST00000375151(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|interpro:IPR019398 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 rogid:Pxy9Lzi0Jtk/725OCbYWo/2FyM49606 intact-crc:A4B54700F745005C|rigid:3zfsR9sOAUfGdqnRqhAVeXosMpk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZT8 uniprotkb:Q15645 intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351377|imex:IM-20259-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:7DBB20C28402FE88|rigid:/WfchBtl4bcwOuQdZcfMKUDbaF0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UJU6 uniprotkb:Q9H788 intact:EBI-751783|uniprotkb:P84070|uniprotkb:Q6IAI8|uniprotkb:Q96F30|uniprotkb:Q96K74|uniprotkb:Q9HBN8|uniprotkb:Q9NR72|uniprotkb:A4D2I9|uniprotkb:B4DEM2|uniprotkb:C9J7P1|uniprotkb:B4DDP6|intact:EBI-28973053|ensembl:ENSP00000411701 intact:EBI-747035|uniprotkb:Q5XKC1|uniprotkb:Q6NXE9|uniprotkb:Q86YM2|uniprotkb:Q96C88|uniprotkb:Q9H7F7|intact:EBI-2558037|uniprotkb:B4DDR1|ensembl:ENSP00000265807|ensembl:ENSP00000428684 psi-mi:dbnl_human(display_long)|uniprotkb:Drebrin-F(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Cervical SH3P7(gene name synonym)|uniprotkb:HPK1-interacting protein of 55 kDa(gene name synonym)|uniprotkb:Cervical mucin-associated protein(gene name synonym)|uniprotkb:DBNL(gene name)|psi-mi:DBNL(display_short)|uniprotkb:CMAP(gene name synonym)|uniprotkb:SH3P7(gene name synonym)|uniprotkb:PP5423(orf name) psi-mi:sh24a_human(display_long)|uniprotkb:SH2D4A(gene name)|psi-mi:SH2D4A(display_short)|uniprotkb:SH2A(gene name synonym)|uniprotkb:"Protein SH(2)A"(gene name synonym)|uniprotkb:PPP1R38(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 38(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351389|imex:IM-20259-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271242.1|refseq:NP_001271244.1|refseq:NP_001014436.1|refseq:NP_001116428.1|refseq:NP_054782.2|ensembl:ENST00000440166|ensembl:ENSP00000415173|ensembl:ENSP00000411701|ensembl:ENST00000456905|ensembl:ENSP00000416421|ensembl:ENST00000468694|ensembl:ENSP00000417653|ensembl:ENST00000490734|ensembl:ENSP00000417749|ensembl:ENST00000494774|ensembl:ENSP00000419992|ensembl:ENSG00000136279(gene)|ensembl:ENST00000448521(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|interpro:IPR035717|interpro:IPR036028|mint:Q9UJU6|rcsb pdb:1X67|reactome:R-HSA-264870|reactome:R-HSA-6794361|reactome:R-HSA-6798695 refseq:NP_001167630.1|refseq:NP_001167631.1|refseq:NP_071354.2|ensembl:ENSG00000104611(gene)|ensembl:ENST00000265807(transcript)|ensembl:ENST00000519207(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:OOa7vGOHVCiCKA9Wt0YUYGR5cu09606 rogid:e7Zi+tTx/rZ4AXx9lSuBz0BmLqI9606 intact-crc:BF271DE92FED3DC1|rigid:jdorckah2l21ZjDQwFNrY31yiPk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14 uniprotkb:Q9Y467 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-746180|uniprotkb:B2RMX6|uniprotkb:B9EGK8|uniprotkb:Q8N656|uniprotkb:Q9Y4G1|ensembl:ENSP00000483562 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:sall2_human(display_long)|uniprotkb:SALL2(gene name)|psi-mi:SALL2(display_short)|uniprotkb:KIAA0360(gene name synonym)|uniprotkb:SAL2(gene name synonym)|uniprotkb:ZNF795(gene name synonym)|uniprotkb:Zinc finger protein 795(gene name synonym)|uniprotkb:Zinc finger protein SALL2(gene name synonym)|uniprotkb:Zinc finger protein Spalt-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351385|imex:IM-20259-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_001278375.1|refseq:NP_005398.2|refseq:NP_001278376.1|ensembl:ENSG00000165821(gene)|ensembl:ENST00000614342(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y467 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:iLP/BSIXETLN/cygMJ/+/bmO1xE9606 intact-crc:8BE7A17CCEA65BBC|rigid:FaKy1T5yblqPV5uK0f/zN311DlM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99961 uniprotkb:Q9H788 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 intact:EBI-747035|uniprotkb:Q5XKC1|uniprotkb:Q6NXE9|uniprotkb:Q86YM2|uniprotkb:Q96C88|uniprotkb:Q9H7F7|intact:EBI-2558037|uniprotkb:B4DDR1|ensembl:ENSP00000265807|ensembl:ENSP00000428684 psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:sh24a_human(display_long)|uniprotkb:SH2D4A(gene name)|psi-mi:SH2D4A(display_short)|uniprotkb:SH2A(gene name synonym)|uniprotkb:"Protein SH(2)A"(gene name synonym)|uniprotkb:PPP1R38(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 38(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351393|imex:IM-20259-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 refseq:NP_001167630.1|refseq:NP_001167631.1|refseq:NP_071354.2|ensembl:ENSG00000104611(gene)|ensembl:ENST00000265807(transcript)|ensembl:ENST00000519207(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019902"(phosphatase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR036860 - crc64:6E5BE978BC955077 - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rogid:e7Zi+tTx/rZ4AXx9lSuBz0BmLqI9606 intact-crc:D940DC36F5F2E106|rigid:nO/xHRqTHMtJMAuomAYIW+IL5UQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21673 uniprotkb:Q9BYD2 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351397|imex:IM-20259-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606 intact-crc:E07C4DBB0D4634AD|rigid:5G5hS3vbi5LmLCsysl8ahFQAqgI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H7E9 uniprotkb:Q99750 intact:EBI-715389|uniprotkb:A6NGC0|uniprotkb:Q96BT8|ensembl:ENSP00000330361 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:ch033_human(display_long)|uniprotkb:C8orf33(gene name)|psi-mi:C8orf33(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351401|imex:IM-20259-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075568.1|ensembl:ENSG00000182307(gene)|ensembl:ENST00000331434(transcript)|interpro:IPR029274|mint:Q9H7E9 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:R2UNBJ/dYewCXrmuO3E9apROd+Q9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:045A76D3FDFDD67A|rigid:c5H0FhuY9a2VoV0g1+nU1ca10PE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q9BV99 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-2350424|uniprotkb:B3KUW0|uniprotkb:D3DWY8|ensembl:ENSP00000339047|ensembl:ENSP00000352642|ensembl:ENSP00000420560 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:lrc61_human(display_long)|uniprotkb:LRRC61(gene name)|psi-mi:LRRC61(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351405|imex:IM-20259-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:XP_006716158.1|refseq:NP_001136400.1|refseq:NP_076431.1|ensembl:ENSG00000127399(gene)|ensembl:ENST00000323078(transcript)|ensembl:ENST00000359623(transcript)|ensembl:ENST00000493307(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:LIU9hAGgEAFLuJqz4NrHn6a0vFc9606 intact-crc:A25BD8577107580A|rigid:x91rUIVqOw17UVHvjBWTAkGHluQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P60880 uniprotkb:Q9Y3C0 intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17|ensembl:ENSP00000254976 intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74 psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym) psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351409|imex:IM-20259-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:NP_003072.2|refseq:NP_570824.1|ensembl:ENSG00000132639(gene)|ensembl:ENST00000254976(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:XP_016883511.1|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|dip:DIP-34554N ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606 rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606 intact-crc:69C34BAF4BB660F6|rigid:gD4sD9ytpcGTsmtxXqJ4gd+Fo4E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95073 uniprotkb:Q14241 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-742350|uniprotkb:Q8IXH1|uniprotkb:B2R7Q8|ensembl:ENSP00000395574|ensembl:ENSP00000484196 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:eloa1_human(display_long)|uniprotkb:ELOA(gene name)|psi-mi:ELOA(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:TCEB3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym)|uniprotkb:MSTP059(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351417|imex:IM-20259-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_003189.2|ensembl:ENSG00000011007(gene)|ensembl:ENST00000418390(transcript)|ensembl:ENST00000613537(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0070449"(elongin complex)|go:"GO:0090734"(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|mint:Q14241|rcsb pdb:4HFX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:5gE87SPNXNcx+LQDo1Jwt/t9yfI9606 intact-crc:9F989BB7C8D395F0|rigid:L3uHlzy9g7uAxPL+K8cWLBewJ1c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12983 uniprotkb:O60238 intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym) psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351413|imex:IM-20259-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2 refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 - crc64:53967696EDA005E2 - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2017/06/28 rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 intact-crc:6A83FB69FB1AFFAA|rigid:+CMlEG2w64qzjQId5D7P6nS0upc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:P35590 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-2256865|uniprotkb:B5A949|uniprotkb:B5A950|ensembl:ENSP00000361554 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:tie1_human(display_long)|uniprotkb:TIE1(gene name)|psi-mi:TIE1(display_short)|uniprotkb:TIE(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351421|imex:IM-20259-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_005415.1|ensembl:ENSG00000066056(gene)|ensembl:ENST00000372476(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001936"(regulation of endothelial cell proliferation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007498"(mesoderm development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0060836"(lymphatic endothelial cell differentiation)|go:"GO:0060854"(branching involved in lymph vessel morphogenesis)|go:"GO:1901201"(regulation of extracellular matrix assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036179|mint:P35590|rcsb pdb:5N06 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:/tuK6SwU9CCcxFhdQo/rlvlPZRg9606 intact-crc:B7209E27053F7D7A|rigid:B60ZsKzcvc2nshgu+Ua0WCzxXnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:P55055 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745354|uniprotkb:Q12970|uniprotkb:Q5I0Y1|uniprotkb:A8K490|uniprotkb:B4DNM6|uniprotkb:E7EWA6|ensembl:ENSP00000253727|ensembl:ENSP00000471194|ensembl:ENSP00000499121 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:nr1h2_human(display_long)|uniprotkb:Ubiquitously-expressed nuclear receptor(gene name synonym)|uniprotkb:Nuclear receptor NER(gene name synonym)|uniprotkb:Liver X receptor beta(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 2(gene name synonym)|uniprotkb:NR1H2(gene name)|psi-mi:NR1H2(display_short)|uniprotkb:LXRB(gene name synonym)|uniprotkb:NER(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351425|imex:IM-20259-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001243576.1|refseq:NP_009052.3|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0090108"(positive regulation of high-density lipoprotein particle assembly)|go:"GO:0090187"(positive regulation of pancreatic juice secretion)|go:"GO:0090340"(positive regulation of secretion of lysosomal enzymes)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:P55055|rcsb pdb:1P8D|rcsb pdb:1PQ6|rcsb pdb:1PQ9|rcsb pdb:1PQC|rcsb pdb:1UPV|rcsb pdb:1UPW|rcsb pdb:3KFC|rcsb pdb:3L0E|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4NQA|rcsb pdb:4RAK|rcsb pdb:5HJP|rcsb pdb:5I4V|rcsb pdb:5JY3|rcsb pdb:5KYA|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|rcsb pdb:5KYJ|rcsb pdb:6JIO|rcsb pdb:6K9G|rcsb pdb:6K9H|rcsb pdb:6S4N|rcsb pdb:6S4T|rcsb pdb:6S4U|rcsb pdb:6S5K|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|rcsb pdb:6K9M|ensembl:ENSG00000131408(gene)|ensembl:ENST00000253727(transcript)|ensembl:ENST00000593926(transcript)|ensembl:ENST00000652203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|dip:DIP-53004N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:fkzJzzYByUN5vk9G6GWcy8LDV249606 intact-crc:9BD232FCF19F5CBE|rigid:UB+tZRjqtbojEthDGOJITdSzW+U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q15777 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-2350461|uniprotkb:D3DQZ5|uniprotkb:E9PB10|uniprotkb:Q59GE6|ensembl:ENSP00000350833 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:mppd2_human(display_long)|uniprotkb:MPPED2(gene name)|psi-mi:MPPED2(display_short)|uniprotkb:Metallophosphoesterase domain-containing protein 2(gene name synonym)|uniprotkb:C11orf8(gene name synonym)|uniprotkb:FAM1B(gene name synonym)|uniprotkb:Fetal brain protein 239(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351437|imex:IM-20259-396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001575.1|refseq:XP_005253167.1|refseq:XP_005253168.1|refseq:XP_005253169.1|refseq:NP_001138871.1|refseq:XP_016873721.1|ensembl:ENSG00000066382(gene)|ensembl:ENST00000358117(transcript)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0016208"(AMP binding)|go:"GO:0019002"(GMP binding)|go:"GO:0030145"(manganese ion binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR024201|interpro:IPR029052|mint:Q15777 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:5Z5lEMdW3jMbovZbzRl+VKelpFc9606 intact-crc:8380518A51B01FA0|rigid:6lTK6XAkNeJE2Zs9D6AymV4GZ2U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96MA1 uniprotkb:P50552 intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short) psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351433|imex:IM-20259-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500 refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 intact-crc:FA6FC61F71CA34D8|rigid:o+I+ZNjyOlWeV1ldgBSidxQWyls false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50552 uniprotkb:P21673 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351429|imex:IM-20259-394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 intact-crc:758A73004F609CD8|rigid:YmzYDUSxZhnRWfTVTQv3LqtJ2UQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52737 uniprotkb:Q99750 intact:EBI-749129|intact:EBI-28979907|ensembl:ENSP00000344162 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:zn136_human(display_long)|uniprotkb:ZNF136(gene name)|psi-mi:ZNF136(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351441|imex:IM-20259-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196646(gene)|ensembl:ENST00000343979(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSP00000344162|refseq:NP_003428.1|refseq:NP_001334942.1|refseq:NP_001334943.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xPCe6HPmMLKQd8v9K4qwiHptc6c9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:0CE35F5FE02CFD78|rigid:1mMNX3DNPol3ZDG9rbpjXIBIoM0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52737 uniprotkb:Q8NHQ1 intact:EBI-749129|intact:EBI-28979907|ensembl:ENSP00000344162 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:zn136_human(display_long)|uniprotkb:ZNF136(gene name)|psi-mi:ZNF136(display_short) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351445|imex:IM-20259-398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196646(gene)|ensembl:ENST00000343979(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSP00000344162|refseq:NP_003428.1|refseq:NP_001334942.1|refseq:NP_001334943.1 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xPCe6HPmMLKQd8v9K4qwiHptc6c9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:F4B6FA8213987EA7|rigid:9VevDaBc+GC4yKGwYajWeOZXeJk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q969V5 uniprotkb:Q92624 intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351453|imex:IM-20259-400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:0D031DF1A297B24C|rigid:tZ++17R2PuDO8OzC22aJBeYUl50 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q0VDD7 uniprotkb:Q13155 intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49 intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950 psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym) psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351457|imex:IM-20259-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1 refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606 rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606 intact-crc:D27CE3FC1EDB5B38|rigid:m2zeqai27W1YDAvYC+WtqkVZfwg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BU76 uniprotkb:Q8NHQ1 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351449|imex:IM-20259-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:FD5AE2504840AB8F|rigid:VMMZFEtneF8ujH0WCqJDL7zkLZI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P33316 uniprotkb:Q9H8W4 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351465|imex:IM-20259-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:28E740CCB4855A03|rigid:QzHKfr7vJyErMTHGN/mFnr0nkTI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8W4 uniprotkb:Q9UI14 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351461|imex:IM-20259-402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:A2A0598F27C542DF|rigid:V1HtlueHMmJd83kIXvCPGdMzac8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:Q9H8W4 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351473|imex:IM-20259-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:4644573FB753853D|rigid:+28ltjd9ncyfuhWImQpmMmepAz8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8W4 uniprotkb:Q8N7W2 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351469|imex:IM-20259-404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:895605D8F85B2946|rigid:3owNjwJOEEVNdD9JRg2D8AN2ZH4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UKG1 uniprotkb:Q9H8W4 intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351477|imex:IM-20259-406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:6BB20C76BFC39851|rigid:50Of/M1XhilwSSjXVf2FOM+xYHk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8W4 uniprotkb:Q9UKJ5 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-741528|ensembl:ENSP00000263921|uniprotkb:B2R639 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:chic2_human(display_long)|uniprotkb:BrX-like translocated in leukemia(gene name synonym)|uniprotkb:CHIC2(gene name)|psi-mi:CHIC2(display_short)|uniprotkb:BTL(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351481|imex:IM-20259-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_036242.1|ensembl:ENSG00000109220(gene)|ensembl:ENST00000263921(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019383|interpro:IPR039735 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:pdPnbCymmDTe6+o8PTDcQT595nY9606 intact-crc:AB97D134E4C03BBF|rigid:DjYgz/pwdG2DANbTmsio7Q+Oyng false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8W4 uniprotkb:Q9NS73 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351485|imex:IM-20259-408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:030372FE8C1D4FB2|rigid:CHE78vCtqOS4cNGojbvVwjRCbYY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10644 uniprotkb:Q9H8W4 intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351489|imex:IM-20259-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 intact-crc:5621515271F93477|rigid:I/npVLJrWLCbhxsuC24VPrcVpYE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H9D4 uniprotkb:O95751 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351497|imex:IM-20259-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:1495A5B108BB9E60|rigid:1pDPnxScAc+R75SfA0pD8mR0NbU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H8W4 uniprotkb:Q9HAF1 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351493|imex:IM-20259-410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 intact-crc:E0FF237A9C797DBF|rigid:tYlRUruw/xcH8OggWqs9lrSNBCo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86TA1 uniprotkb:P49902 intact:EBI-751703|uniprotkb:Q8NEB4|uniprotkb:Q9H8V4|ensembl:ENSP00000262244 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:mob3b_human(display_long)|uniprotkb:MOB3B(gene name)|psi-mi:MOB3B(display_short)|uniprotkb:MOBKL2B(gene name synonym)|uniprotkb:Mob1 homolog 2b(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2B(gene name synonym)|uniprotkb:C9orf35(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351509|imex:IM-20259-414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079037.3|ensembl:ENSG00000120162(gene)|ensembl:ENST00000262244(transcript)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703 ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:dMFNTMjJM+gWq3lR6v64Pal5pj89606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:34C294F872D6D133|rigid:Zcr356UTenu6pwppFtFtjL5pCuM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H9D4 uniprotkb:Q8NHQ1 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351505|imex:IM-20259-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:B8676EBC5D2B90D6|rigid:ajHJwN45mIZHLofRE6B/JDkkyzg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q9H9D4 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351501|imex:IM-20259-412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:FB799398D07521FA|rigid:CMeD+kGCxsHkAnS8q/1sa1ULFWI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q9H5Z6 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-741626|uniprotkb:A6NNC7|uniprotkb:Q8NBZ4|uniprotkb:Q8TAV7|ensembl:ENSP00000386895 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:f124b_human(display_long)|uniprotkb:FAM124B(gene name)|psi-mi:FAM124B(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351513|imex:IM-20259-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001116251.1|refseq:NP_079061.2|ensembl:ENSG00000124019(gene)|ensembl:ENST00000409685(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|interpro:IPR029380 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:HFD1ZzsJklUdYLe4z2+GKU+Owi89606 intact-crc:ADEEAA2F41C83ED5|rigid:xq7p3KB+5oo639bDvOiFzlvYV8M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q6ZVK8 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351517|imex:IM-20259-416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:05605B8230AEE292|rigid:j55kQipEe1jmC48Fhmjmlj0SBK8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:P22234 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351521|imex:IM-20259-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 intact-crc:221E59FBED5002F2|rigid:vT0Zc8UymEoEHM5Ebv4ZOy0IjJE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:Q96CN4 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351525|imex:IM-20259-418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606 intact-crc:7872B2CFBCBBE63F|rigid:B7lG6WL5Be8NBR7bCT85KmVxNxk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:P49366 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351529|imex:IM-20259-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 intact-crc:0B48B08A655AB4D8|rigid:B5LmTbTiyrjJ+HOhyq1bLaAb1Lo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95073 uniprotkb:Q6ZVK8 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351541|imex:IM-20259-422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:0835D6F36F5BDC89|rigid:CgNbKACrO7i7cihHCwLucJ5gvjo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:P49902 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351537|imex:IM-20259-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:02652AA78D1B1A17|rigid:FZgQHxpf/aK/ew5cObiPj0qwtIA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P33316 uniprotkb:Q6ZVK8 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351533|imex:IM-20259-420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:E5C9262F3ADDED66|rigid:1XhqhHNsaC3kh9T4PWetxZwGSy0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BTE0 uniprotkb:Q6ZVK8 intact:EBI-711919|uniprotkb:Q9BTD0|uniprotkb:Q9Y3T3|uniprotkb:B2R7F0|ensembl:ENSP00000350467 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:nat9_human(display_long)|uniprotkb:Embryo brain-specific protein(gene name synonym)|uniprotkb:NAT9(gene name)|psi-mi:NAT9(display_short)|uniprotkb:EBS(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351545|imex:IM-20259-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056469.2|refseq:NP_001292006.1|refseq:NP_001292007.1|refseq:NP_001292008.1|refseq:NP_001292009.1|refseq:NP_001292010.1|refseq:NP_001292011.1|refseq:NP_001292012.1|refseq:NP_001292013.1|refseq:NP_001292014.1|refseq:NP_001292015.1|refseq:NP_001292016.1|refseq:NP_001292017.1|ensembl:ENSG00000109065(gene)|ensembl:ENST00000357814(transcript)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0032991"(protein-containing complex)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR039135 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:uBtAvUPRnyCN0NdUxtoJg7d3Ygw9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:5EA3CFBD86B37AE6|rigid:k/eLnxuPUeZmYk7T/1cLOaAt9hA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GX9 uniprotkb:Q6ZVK8 intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351549|imex:IM-20259-424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:DDB8CE20FA3D17A7|rigid:bnJdFlrXJJVoCwN8OGnWr/Isi5w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BPX1 uniprotkb:Q6ZVK8 intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name) psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351553|imex:IM-20259-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144 refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 intact-crc:0A48AFD5F0A1B070|rigid:FPYbOdDvJDEjg3y/sgRgBpuAHzY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:Q15633 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351561|imex:IM-20259-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 intact-crc:1052D79FE17683AA|rigid:vkDCQKhyAUFDTwG4WPPwcd5kJaU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZVK8 uniprotkb:Q8TBN0 intact:EBI-740486|intact:EBI-954151|ensembl:ENSP00000480722|uniprotkb:Q9H687|uniprotkb:Q8IZ75 intact:EBI-743796|uniprotkb:Q86V32|uniprotkb:Q9P1Q8|ensembl:ENSP00000378313 psi-mi:nud18_human(display_long)|uniprotkb:NUDT18(gene name)|psi-mi:NUDT18(display_short)|uniprotkb:2-hydroxy-dADP phosphatase(gene name synonym)|uniprotkb:7,8-dihydro-8-oxoguanine phosphatase(gene name synonym)|uniprotkb:MTH3(gene name synonym)|uniprotkb:MutT homolog 3(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 18(gene name synonym) psi-mi:r3gef_human(display_long)|uniprotkb:Rab-3A-interacting-like protein 1(gene name synonym)|uniprotkb:Rabin3-like 1(gene name synonym)|uniprotkb:RAB3IL1(gene name)|psi-mi:RAB3IL1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351557|imex:IM-20259-426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079091.3|ensembl:ENST00000611621(transcript)|ensembl:ENSG00000275074(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0044717"(8-hydroxy-dADP phosphatase activity)|go:"GO:0046057"(dADP catabolic process)|go:"GO:0046067"(dGDP catabolic process)|go:"GO:0046712"(GDP catabolic process)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|interpro:IPR042970|rcsb pdb:3GG6|rcsb pdb:4HVY|reactome:R-HSA-2393930 refseq:NP_037533.2|refseq:NP_001258615.1|ensembl:ENSG00000167994(gene)|ensembl:ENST00000394836(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|rcsb pdb:4LI0|reactome:R-HSA-8876198 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:IBrXB2HhvhcyxMTQ0Xs5hGiimzA9606 rogid:kT4iWSZ+jRCNm3fDdDR5VhdF81o9606 intact-crc:F26A749B0F236F65|rigid:3B/IipRHezRawv+vtXknf0ZbhVQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q96D16 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744419|uniprotkb:E7EW62|ensembl:ENSP00000481397 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:q96d16_human(display_long)|uniprotkb:FBXL18(gene name)|psi-mi:FBXL18(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351565|imex:IM-20259-428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_079239.3|ensembl:ENSG00000155034(gene)|ensembl:ENST00000620087(transcript) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:Dd8ExGbE2tnHUljANEx2fT5icX09606 intact-crc:B4EE716421FD8F49|rigid:lM45ixLOacvwwfzpeGl3EyRjvI8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:P15407 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351573|imex:IM-20259-430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606 intact-crc:C4BC6B5B326822C4|rigid:ZqBw9zHSkzLHqAd20cDmYB9wPBs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NFT6 uniprotkb:Q99750 intact:EBI-749662|uniprotkb:Q8TEX0|uniprotkb:Q9H912|uniprotkb:Q96B19|uniprotkb:D3DX56|ensembl:ENSP00000323663 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:dbf4b_human(display_long)|uniprotkb:ASKL1(gene name synonym)|uniprotkb:DRF1(gene name synonym)|uniprotkb:Activator of S phase kinase-like protein 1(gene name synonym)|uniprotkb:Dbf4-related factor 1(gene name synonym)|uniprotkb:Chiffon homolog B(gene name synonym)|uniprotkb:DBF4B(gene name)|psi-mi:DBF4B(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351569|imex:IM-20259-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079380.2|refseq:NP_663696.1|refseq:XP_011523583.1|refseq:XP_006722165.1|ensembl:ENSG00000161692(gene)|ensembl:ENST00000315005(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:1901987"(regulation of cell cycle phase transition)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|mint:Q8NFT6|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:BdvmDAqRsWqg1qbvLLc/uVtXEiI9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:36254998A903B09D|rigid:SC2AlIVpKdeatF++L8D+rVylS3E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q9H078 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351577|imex:IM-20259-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606 intact-crc:7A2DF494FAB766DE|rigid:kOEwwgtvaGOVIMGI4czsMC2hjMQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BSH5 uniprotkb:Q15645 intact:EBI-745201|uniprotkb:B2RD47|ensembl:ENSP00000238379|ensembl:ENSP00000363295 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 psi-mi:hdhd3_human(display_long)|uniprotkb:HDHD3(gene name)|psi-mi:HDHD3(display_short)|uniprotkb:C9orf158(gene name synonym) psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351581|imex:IM-20259-432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112496.1|ensembl:ENSG00000119431(gene)|ensembl:ENST00000238379(transcript)|ensembl:ENST00000374180(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR011949(HAD-superfamily hydrolase, subfamily IA, REG-2-like)|interpro:IPR023214|interpro:IPR036412|interpro:IPR041492|rcsb pdb:3K1Z|refseq:NP_001291439.1|refseq:NP_001291440.1|refseq:NP_001291438.1 refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:YX8rSYs8QnEQTmA7uqbY5mrz5nU9606 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 intact-crc:4E857039E24A80BC|rigid:PX9elQ8v6Ex6/c07ZgIsTwtScto false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:P48552 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351585|imex:IM-20259-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 intact-crc:F4C380F8A941B0E1|rigid:lAK4e1G6bb2TYSivIS1vJrfBGCo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P48552 uniprotkb:Q8NHQ1 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351589|imex:IM-20259-434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:EAA6AAEC0D8B2CF9|rigid:pQVodSVVZlKj33wtYnC9fo0M/38 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92624 uniprotkb:Q8WWW0 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 intact:EBI-367390|uniprotkb:Q5SY32|uniprotkb:Q8WWV9|uniprotkb:Q8WXF4|uniprotkb:Q9BT99|uniprotkb:A8K1E6|ensembl:ENSP00000462099 psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:rasf5_human(display_long)|uniprotkb:RAPL(gene name synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351593|imex:IM-20259-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 refseq:NP_872604.1|refseq:NP_872605.1|refseq:NP_872606.1|ensembl:ENSG00000266094(gene)|ensembl:ENST00000579436(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033623|mint:Q8WWW0|rcsb pdb:4LGD|rcsb pdb:4OH8|dip:DIP-32490N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rogid:EqQpr1Zt1laHo0Y23CpTVMnl28Y9606 intact-crc:87118C39807E809B|rigid:lMHDH4gLeo0uGOZm4nwD/cgsEhM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N6Y0 uniprotkb:Q9UJW9 intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597 intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882 psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym) psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351597|imex:IM-20259-436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171 refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606 rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606 intact-crc:031AEFECE3DCB855|rigid:4hk1AXkLx2VSsO/26zqqXbLjEe8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q9BQY4 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351605|imex:IM-20259-438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 intact-crc:982BB18B78D8990D|rigid:PCOXiNbSqdGMD2u2gCxKGeW5+lw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q96JB6 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-749562|uniprotkb:Q96DY1|uniprotkb:Q96PC0|uniprotkb:Q9H6T5|uniprotkb:Q5W0B3|ensembl:ENSP00000260702 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:loxl4_human(display_long)|uniprotkb:Lysyl oxidase-like protein 4(gene name synonym)|uniprotkb:Lysyl oxidase-related protein C(gene name synonym)|uniprotkb:LOXL4(gene name)|psi-mi:LOXL4(display_short)|uniprotkb:LOXC(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351601|imex:IM-20259-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_115587.6|ensembl:ENSG00000138131(gene)|ensembl:ENST00000260702(transcript)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q96JB6|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:yOUffU5WqmaUNvrXvX1ie0RWEG49606 intact-crc:446F53C7D6E1CA65|rigid:spXMno6EeFv/rlvmYonOHTZAWA8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q9BQY4 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351609|imex:IM-20259-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606 intact-crc:C925DF3ED81654CD|rigid:PpV4Q5EMiPYrhtBCnaKrFEa6fsA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q14781 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351613|imex:IM-20259-440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:8DCB960EB0FD6DF5|rigid:Thw1S4/qeodTShbyzC/iajOMLTY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:Q6UX72 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-1170370|uniprotkb:Q96EK0|ensembl:ENSP00000400157 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:b3gn9_human(display_long)|uniprotkb:B3GNT9(gene name)|psi-mi:B3GNT9(display_short)|uniprotkb:UNQ1922/PRO4397(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351617|imex:IM-20259-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_171608.2|ensembl:ENSG00000237172(gene)|ensembl:ENST00000449549(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0008532"(N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030311"(poly-N-acetyllactosamine biosynthetic process)|interpro:IPR002659(Glycosyl transferase, family 31)|reactome:R-HSA-913709 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:ZM7F4khBcuN/9erExui87yIiXFg9606 intact-crc:84F80FCF0D7A9401|rigid:7Ew2bMJ2Jx7znhGAEgObQ1h4FEA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96I34 uniprotkb:Q15654 intact:EBI-710402|ensembl:ENSP00000292539|ensembl:ENSP00000391126|uniprotkb:D3DWM5 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:pp16a_human(display_long)|uniprotkb:Myosin phosphatase-targeting subunit 3(gene name synonym)|uniprotkb:PPP1R16A(gene name)|psi-mi:PPP1R16A(display_short)|uniprotkb:MYPT3(gene name synonym) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351625|imex:IM-20259-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116291.1|ensembl:ENSG00000160972(gene)|ensembl:ENST00000292539(transcript)|ensembl:ENST00000435887(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0017020"(myosin phosphatase regulator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035304"(regulation of protein dephosphorylation)|interpro:IPR002110(Ankyrin)|interpro:IPR017417(Protein phosphatase 1, regulatory subunits 16A/B, eukaryote)|interpro:IPR020683|interpro:IPR036770|refseq:NP_001316371.1|refseq:NP_001316372.1|refseq:NP_001316373.1|refseq:NP_001316374.1|refseq:XP_016869403.1 refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:xEjCGLPSfE2zKdM41klRl4kCfZI9606 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 intact-crc:26C12C581933874E|rigid:UvkPmtX3tq01Zt39t6yT75XCQ7Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15038 uniprotkb:Q96K80 intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62 intact:EBI-742550|ensembl:ENSP00000257940 psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym) psi-mi:zc3ha_human(display_long)|uniprotkb:ZC3H10(gene name)|psi-mi:ZC3H10(display_short)|uniprotkb:ZC3HDC10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351621|imex:IM-20259-442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1 refseq:NP_116175.1|ensembl:ENSG00000135482(gene)|ensembl:ENST00000257940(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0035198"(miRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|refseq:NP_001290053.1|refseq:NP_001290054.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606 rogid:ygcb76R50to+us9MwWeu9tIAq1A9606 intact-crc:BAF96B83D039EFD9|rigid:QZq8ymMgmnwwAhnKMwy4Mor/hMk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:Q13136 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351629|imex:IM-20259-444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:0DBD2CC7B4456A8F|rigid:Jj6QmollMzw7DTfikMovv4u8J8E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13136 uniprotkb:Q8NHQ1 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8 psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351633|imex:IM-20259-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606 intact-crc:3DA894F6EECE2A3D|rigid:gfAm8Hcw9cRoNVp5qWGKjmyrt40 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N381 uniprotkb:Q9NS73 intact:EBI-749096 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:q8n381_human(display_long)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351637|imex:IM-20259-446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107644.1|refseq:NP_003620.3|interpro:IPR000980(SH2 motif)|refseq:NP_001290358.1|interpro:IPR032498|go:"GO:0016301"(kinase activity)|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:5up+bOHxuzcfCaL/loToWudUSMw9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:56EBA711B02FACA7|rigid:tNtgS30Msr//3dXCEY+Rh507ZUk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UY14 uniprotkb:O75716 intact:EBI-742002|uniprotkb:Q5T5F7|uniprotkb:Q6IPM6|uniprotkb:Q8N643|uniprotkb:Q9HBS6|ensembl:ENSP00000271643|ensembl:ENSP00000358034|uniprotkb:B2RTT0|uniprotkb:F8WAD0 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:atl4_human(display_long)|uniprotkb:Thrombospondin repeat-containing protein 1(gene name synonym)|uniprotkb:ADAMTSL4(gene name)|psi-mi:ADAMTSL4(display_short)|uniprotkb:TSRC1(gene name synonym)|uniprotkb:PP1396(orf name)|uniprotkb:UNQ2803/PRO34012(orf name) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351641|imex:IM-20259-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061905.2|refseq:NP_079284.2|ensembl:ENSG00000143382(gene)|ensembl:ENST00000271643(transcript)|ensembl:ENST00000369038(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006915"(apoptotic process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR036383|mint:Q6UY14|reactome:R-HSA-5083635|reactome:R-HSA-5173214|go:"GO:0005576"(extracellular region)|refseq:NP_001275536.1|refseq:NP_001275537.1|refseq:XP_011507950.1|refseq:XP_016856995.1 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:HIXY8OQopS51RVemJo0GTj8V0WQ9606 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 intact-crc:2ACD7DCE399E4611|rigid:fSxVP7/DhCStBDCN9mGZ8qR7MCc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15372 uniprotkb:Q9P2A4 intact:EBI-709735|ensembl:ENSP00000429931 intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6 psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351645|imex:IM-20259-448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606 intact-crc:B20D4E2FF99774DF|rigid:VYqH0PBL28QcO6Vr8kaARKSUuBw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ULZ1 uniprotkb:Q99750 intact:EBI-2350677|uniprotkb:Q8WU89|uniprotkb:Q4VY08|ensembl:ENSP00000391800 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:apel_human(display_long)|uniprotkb:APLN(gene name)|psi-mi:APLN(display_short)|uniprotkb:APEL(gene name synonym)|uniprotkb:APJ endogenous ligand(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351649|imex:IM-20259-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_059109.3|ensembl:ENSG00000171388(gene)|ensembl:ENST00000429967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007595"(lactation)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031652"(positive regulation of heat generation)|go:"GO:0031704"(apelin receptor binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042756"(drinking behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051461"(positive regulation of corticotropin secretion)|go:"GO:0051466"(positive regulation of corticotropin-releasing hormone secretion)|go:"GO:0060183"(apelin receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904022"(positive regulation of G protein-coupled receptor internalization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|interpro:IPR026155|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:sshv16DxSDVM/a2VnhtVpOlDy9c9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:8B4AC3ACD958537E|rigid:SNQY1F7sH+tjfFJWrpvLtwHLJu0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BXS5 uniprotkb:O95751 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351653|imex:IM-20259-450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:FB79966C4E4C9D2A|rigid:ovi2AZAyamdRu9zXWLXfJhVTwFU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GV9 uniprotkb:Q99750 intact:EBI-2350695|ensembl:ENSP00000326110|ensembl:ENSP00000421270|ensembl:ENSP00000422836 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:macir_human(display_long)|uniprotkb:MACIR(gene name)|psi-mi:MACIR(display_short)|uniprotkb:C5orf30(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351661|imex:IM-20259-452 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149988.1|refseq:NP_001303897.1|refseq:NP_001303898.1|ensembl:ENSG00000181751(gene)|ensembl:ENST00000319933(transcript)|ensembl:ENST00000510890(transcript)|ensembl:ENST00000515669(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0015031"(protein transport)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060271"(cilium assembly)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|interpro:IPR029219 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:/pvB3D4aGWrMxx5qNz88Q74DRAs9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:51F623068C7F6B50|rigid:6jsAa3oYmXkToOkctD+YYvKpO/8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35125 uniprotkb:Q99750 intact:EBI-954564|uniprotkb:Q15634|uniprotkb:Q86WP6|uniprotkb:Q8IWT4|ensembl:ENSP00000250066|ensembl:ENSP00000460380 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:ubp6_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:TRE2(gene name synonym)|uniprotkb:HRP1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351665|imex:IM-20259-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004496.2|ensembl:ENST00000250066(transcript)|ensembl:ENST00000574788(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR035969|interpro:IPR038765|interpro:IPR028889|ensembl:ENSG00000129204(gene)|refseq:NP_001291213.1|refseq:XP_011522352.1|refseq:XP_011522353.1|refseq:XP_011522354.1|refseq:XP_011522355.1|refseq:XP_011522356.1|refseq:XP_011522357.1|refseq:XP_011522358.1|refseq:XP_011522361.1|refseq:XP_016880779.1 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:EjN7POQXOUGbHphIDgTYYBqptJE9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:B70F15358374C274|rigid:BUO48jtincB5HV7v5xKXqK73G6c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14872 uniprotkb:Q9BXS5 intact:EBI-747024|uniprotkb:Q96CB1|uniprotkb:B2RAK6|ensembl:ENSP00000362127 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 psi-mi:mtf1_human(display_long)|uniprotkb:Transcription factor MTF-1(gene name synonym)|uniprotkb:MRE-binding transcription factor(gene name synonym)|uniprotkb:MTF1(gene name)|psi-mi:MTF1(display_short) psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351657|imex:IM-20259-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005946.2|refseq:XP_011539793.1|ensembl:ENSG00000188786(gene)|ensembl:ENST00000373036(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0010038"(response to metal ion)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:1990079"(cartilage homeostasis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029796|interpro:IPR036236|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-5660489|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific) refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:zeQhfLuX3GjfLw1B9P+0Rd4eZ4o9606 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 intact-crc:AC09710D58B279E5|rigid:+A9/RTvV7Q26XEZ7fKjFNpxWz9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43439 uniprotkb:Q99750 intact:EBI-748628|uniprotkb:Q5TGE4|uniprotkb:Q5TGE7|uniprotkb:Q8IWF3|uniprotkb:Q96B06|uniprotkb:Q96L00|uniprotkb:Q9H436|uniprotkb:Q9UJP8|uniprotkb:Q9UJP9|uniprotkb:Q9UP24|uniprotkb:B2RAE6|uniprotkb:Q5TGE5|uniprotkb:Q5TGE6|uniprotkb:F8W6D7|intact:EBI-28968245|ensembl:ENSP00000262653|ensembl:ENSP00000364428 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:mtg8r_human(display_long)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351669|imex:IM-20259-454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000342704|ensembl:ENSP00000345810|ensembl:ENST00000344201|ensembl:ENSP00000341865|ensembl:ENSP00000262653|ensembl:ENST00000359606|ensembl:ENSP00000352622|ensembl:ENSP00000364428|ensembl:ENST00000397800|ensembl:ENSP00000380902|ensembl:ENST00000492345|ensembl:ENSP00000433270|refseq:NP_001028171.1|refseq:NP_001034798.1|refseq:NP_005084.1|refseq:XP_011527403.1|refseq:XP_011527405.1|refseq:XP_016883610.1|ensembl:ENSG00000078699(gene)|ensembl:ENST00000346541(transcript)|ensembl:ENST00000375279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060575"(intestinal epithelial cell differentiation)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR013289(Eight-Twenty-One)|interpro:IPR013291("Myeloid transforming gene related protein-1 (MTGR1)")|interpro:IPR014896(NHR2-like)|interpro:IPR037249|dip:DIP-38274N refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:iuVAi35hwfEn/uJ+HjB0Cr+TXdg9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:C1A9003DD1470381|rigid:6Ai4K2d8jpYNqWjR9+8yemP+O/w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BS34 uniprotkb:Q99750 intact:EBI-745276|intact:EBI-28980552|ensembl:ENSP00000355459 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:zn670_human(display_long)|uniprotkb:ZNF670(gene name)|psi-mi:ZNF670(display_short) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351673|imex:IM-20259-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149990.1|ensembl:ENSP00000355459|ensembl:ENSG00000277462(gene)|ensembl:ENST00000366503(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q9BS34|reactome:R-HSA-212436 refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:rLN4zdWhS14BhRLxojEevuc2Knc9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:06BA790C8FEA1F7A|rigid:r2EWiUv+9PIce8jahRY3GpPKby4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4U2R8 uniprotkb:Q92624 intact:EBI-749741|uniprotkb:B2D0R6|uniprotkb:A8MY93|uniprotkb:O95187|uniprotkb:O95742|uniprotkb:Q7LDA0|uniprotkb:Q9NQA6|uniprotkb:Q9NQC2|uniprotkb:Q9UBG6|uniprotkb:Q9UEQ8|uniprotkb:Q8N192|ensembl:ENSP00000367102 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:s22a6_human(display_long)|uniprotkb:Organic anion transporter 1(gene name synonym)|uniprotkb:Renal organic anion transporter 1(gene name synonym)|uniprotkb:PAH transporter(gene name synonym)|uniprotkb:SLC22A6(gene name)|psi-mi:SLC22A6(display_short)|uniprotkb:PAHT(gene name synonym)|uniprotkb:OAT1(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351677|imex:IM-20259-456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004781.2|refseq:NP_695008.1|refseq:NP_695009.1|refseq:NP_695010.1|ensembl:ENSG00000197901(gene)|ensembl:ENST00000377871(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015347"(sodium-independent organic anion transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015742"(alpha-ketoglutarate transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043252"(sodium-independent organic anion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097254"(renal tubular secretion)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-561048 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:hAE4k7HdfkEQ4drVBOtmwmRGHPA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 intact-crc:02DC047A2378306F|rigid:Bs2hogWnFHu93CMSP7JFtzxsGZ4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UI14 uniprotkb:Q14088 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 intact:EBI-744685|uniprotkb:Q5JUZ6|uniprotkb:Q92465|ensembl:ENSP00000257017 psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:rb33a_human(display_long)|uniprotkb:Small GTP-binding protein S10(gene name synonym)|uniprotkb:RAB33A(gene name)|psi-mi:RAB33A(display_short)|uniprotkb:RABS10(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351681|imex:IM-20259-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 refseq:NP_004785.1|interpro:IPR041822|reactome:R-HSA-8854214|reactome:R-HSA-8873719|interpro:IPR027417|ensembl:ENSG00000134594(gene)|ensembl:ENST00000257017(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0032482"(Rab protein signal transduction)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rogid:E97stXWvkGPUamSzsiejNoY4S789606 intact-crc:4C5CC333AFBAB626|rigid:Ac4U/nds3nAuhLfiUivGIxKT/ao false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P2A4 uniprotkb:Q9NSC5 intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351685|imex:IM-20259-458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4 ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:DD8F08E937BFB5E8|rigid:iX1dl5QpwdPYrze5Lm3JNCs6pOk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NRA8 uniprotkb:O60573 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351693|imex:IM-20259-460 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 intact-crc:92BFBB6B73AC116E|rigid:ONAv64ZsDxcEWzgaDct7GZWJcQY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O60573 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351689|imex:IM-20259-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 intact-crc:753C74EB41A4197E|rigid:8olfyGESn/Vha3/gRUE19n3vADI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92530 uniprotkb:O43251 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351701|imex:IM-20259-462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 intact-crc:EFD8A09595611ABE|rigid:sxnqSEJY9bNXlruxVMg3hiy7U+0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92530 uniprotkb:Q8N7W2 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351697|imex:IM-20259-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:320544D51295202F|rigid:YkEW55SeCj3wQi0pxkmBYWhGRJw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95751 uniprotkb:Q92530 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351705|imex:IM-20259-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:FD1716325D9D8C54|rigid:prdiGQU1tu0b1I+wMHguz6OrFAE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P286 uniprotkb:Q92530 intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351709|imex:IM-20259-464 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1 refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2017/06/28 rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:80796EF5EA46C94F|rigid:xnUJnGPBQOfOXebXeLsCkvMoYVU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:Q9UI14 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351713|imex:IM-20259-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 intact-crc:C2571C5F065C1E2D|rigid:QQ7/P3SIvRD/GVYrdvrwPOgxdpw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:P49902 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351721|imex:IM-20259-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 intact-crc:C035DAC4BA8E5733|rigid:ygYmKOIbpkQ4xldTaBfD+w0BQCI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22234 uniprotkb:P51116 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351717|imex:IM-20259-466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:E04EA998DAC54FD6|rigid:WF2JcoPmSVn4yK5uiEnbVNMRIdg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:O95751 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351729|imex:IM-20259-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606 intact-crc:493AC1BF0E9E7F7C|rigid:mf7a8+RUdj6sUmGK/EsqGcHBXPQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15041 uniprotkb:P51116 intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351725|imex:IM-20259-468 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:AB4DDF2D6200069B|rigid:jB4s95tqsqv5w2wJxvTg4fhKdcc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36406 uniprotkb:P51116 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351733|imex:IM-20259-470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:172DEB347170928D|rigid:vJ3eZ+BX7BBvk9tYbZI4jPc03Is false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NS73 uniprotkb:P51116 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351741|imex:IM-20259-472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:63F4372EAD841340|rigid:rgmjIdSL7wKWGtbUz2NkaVUzHsc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:Q03393 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351745|imex:IM-20259-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 intact-crc:AC9FE4C306043152|rigid:aInqzdOHHpgP03GkXniJmnG9xeY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51116 uniprotkb:P15531 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351737|imex:IM-20259-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 intact-crc:D0D28F57D5B9ACF5|rigid:16jCoZwOCQ8jVi3mIRoUn7pPyf0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HAF1 uniprotkb:P51116 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351749|imex:IM-20259-474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:800866AABDE0214D|rigid:JwKG5VaPI4SP3fZz7h6AaRaM1+A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99988 uniprotkb:Q99750 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351753|imex:IM-20259-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 intact-crc:B527F69442048754|rigid:zB2V95ynBl+IfWVjoN4n+6XpmuY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15645 uniprotkb:Q15013 intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351757|imex:IM-20259-476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:2E8F3E81013E7261|rigid:jkJRGdox7pnZgRBGxhvxnW9SXA8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O15015 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-745608|uniprotkb:Q8IVD8|ensembl:ENSP00000300850 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zn646_human(display_long)|uniprotkb:KIAA0296(gene name synonym)|uniprotkb:ZNF646(gene name)|psi-mi:ZNF646(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351761|imex:IM-20259-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_055514.3|refseq:XP_011544292.1|ensembl:ENSG00000167395(gene)|ensembl:ENST00000300850(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_005255767.1|refseq:XP_005255768.1 - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2019/07/08 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:LLCOZY29R+2cHozH65lymJNIjRU9606 intact-crc:E3AFCA075C39345E|rigid:ayJVYJcoGWhzsORFRtb8FASZUkQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99750 uniprotkb:O43167 intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142 intact:EBI-744471|uniprotkb:Q17RC6|uniprotkb:Q5TED5|uniprotkb:Q8N455|ensembl:ENSP00000230122 psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short) psi-mi:zbt24_human(display_long)|uniprotkb:Zinc finger protein 450(gene name synonym)|uniprotkb:ZBTB24(gene name)|psi-mi:ZBTB24(display_short)|uniprotkb:KIAA0441(gene name synonym)|uniprotkb:ZNF450(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Venkatesan et al. (2009) pubmed:19060904|imex:IM-20259 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2351765|imex:IM-20259-478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1 refseq:NP_001157785.1|refseq:NP_055612.2|ensembl:ENSG00000112365(gene)|ensembl:ENST00000230122(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O43167|interpro:IPR000210(BTB/POZ-like) - - - figure legend:supplemental Table S8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/06/05 2014/10/16 rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606 rogid:78JpKudyjkcnvRT5hMeTyp9rXnU9606 intact-crc:C540E4761300E59A|rigid:ux5tyR5xsv2ONCxW5UXQP01hkF8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)