#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0CG63 uniprotkb:P38925 intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838 intact:EBI-17437|uniprotkb:D6W1U6|ensemblfungi:YOL122C psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:smf1_yeast(display_long)|uniprotkb:YOL122C(locus name)|uniprotkb:SMF1(gene name)|psi-mi:SMF1(display_short)|uniprotkb:ESP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nikko et al. (2008) pubmed:18953286|imex:IM-11635|mint:MINT-6810184|doi:10.1038/embor.2008.199 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8473865|mint:MINT-6810280|imex:IM-11635-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-6810283(identity) refseq:NP_014519.1|sgd:S000005482|interpro:IPR001046(Natural resistance-associated macrophage protein)|ensemblfungi:YOL122C(gene)|ensemblfungi:YOL122C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006825"(copper ion transport)|go:"GO:0006826"(iron ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006876"(cellular cadmium ion homeostasis)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015295"("solute:proton symporter activity")|go:"GO:0015691"(cadmium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0046872"(metal ion binding)|mint:P38925|mint:MINT-6810282(identity) - function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint - figure legend:f1c|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/01/07 2014/10/16 rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292 rogid:92t8suj+L7yRdqmfcvLO/7znimE559292 intact-crc:3C238175D82EA281|rigid:70cj+k6KdDqkKVRklT4lyDX2Dlc false myc tag:?-?(MINT-6810475) green fluorescent protein tag:?-?(MINT-6810533) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38167 uniprotkb:P38925 intact:EBI-21359|uniprotkb:D6VPQ2|ensemblfungi:YBL101C intact:EBI-17437|uniprotkb:D6W1U6|ensemblfungi:YOL122C psi-mi:ecm21_yeast(display_long)|uniprotkb:YBL101C(locus name)|uniprotkb:YBL0814(orf name)|uniprotkb:ECM21(gene name)|psi-mi:ECM21(display_short)|uniprotkb:Extracellular mutant protein 21(gene name synonym) psi-mi:smf1_yeast(display_long)|uniprotkb:YOL122C(locus name)|uniprotkb:SMF1(gene name)|psi-mi:SMF1(display_short)|uniprotkb:ESP1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nikko et al. (2008) pubmed:18953286|imex:IM-11635|mint:MINT-6810184|doi:10.1038/embor.2008.199 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8473893|mint:MINT-6820973|imex:IM-11635-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009449.1|sgd:S000000197|mint:P38167|dip:DIP-791N|ensemblfungi:YBL101C(gene)|ensemblfungi:YBL101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|go:"GO:0071555"(cell wall organization)|interpro:IPR011022(Arrestin-like, C-terminal)|mint:MINT-6820975(identity) refseq:NP_014519.1|sgd:S000005482|interpro:IPR001046(Natural resistance-associated macrophage protein)|ensemblfungi:YOL122C(gene)|ensemblfungi:YOL122C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006825"(copper ion transport)|go:"GO:0006826"(iron ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006876"(cellular cadmium ion homeostasis)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015295"("solute:proton symporter activity")|go:"GO:0015691"(cadmium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0046872"(metal ion binding)|mint:P38925|mint:MINT-6820979(identity) - - - figure legend:f4 f5d|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/01/07 2014/10/16 rogid:QZYFcUGl4kmJOxb5Cus+sulNaX4559292 rogid:92t8suj+L7yRdqmfcvLO/7znimE559292 intact-crc:6A53C134660CCDC6|rigid:xBBcwuubzl62ewtxOtpOkIlgeNQ false ha tag:?-?(MINT-6820976) green fluorescent protein tag:?-?(MINT-6820980) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)