#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q03018	uniprotkb:Q08581	intact:EBI-6657|uniprotkb:D6VUN0|ensemblfungi:YGR098C	intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W	psi-mi:esp1_yeast(display_long)|uniprotkb:ESP1(gene name)|psi-mi:ESP1(display_short)|uniprotkb:YGR098C(locus name)|uniprotkb:Separase(gene name synonym)	psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rahal et al. (2008)	pubmed:18927509|imex:IM-19190	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2133638|imex:IM-19190-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003330|refseq:NP_011612.3|dip:DIP-2933N|mint:Q03018|ensemblfungi:YGR098C(gene)|ensemblfungi:YGR098C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006915"(apoptotic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|rcsb pdb:5U1S|rcsb pdb:5U1T|reactome:R-SCE-2467813	sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312	-	-	-	figure legend:Fig 1A, 1B, 1C, 2E|comment:Interaction occurs in M-phase.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/07	2014/10/16	rogid:UMTGDO9alhQOMP7ZXNTEDs/ZB68559292	rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292	intact-crc:21796B1D72CA603D|rigid:pJFu0ZusZFpLnOzmnEHaA2LKtXw	false	myc tag:c-c	protein a tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q03018	uniprotkb:P32562	intact:EBI-6657|uniprotkb:D6VUN0|ensemblfungi:YGR098C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:esp1_yeast(display_long)|uniprotkb:ESP1(gene name)|psi-mi:ESP1(display_short)|uniprotkb:YGR098C(locus name)|uniprotkb:Separase(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rahal et al. (2008)	pubmed:18927509|imex:IM-19190	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2133646|imex:IM-19190-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003330|refseq:NP_011612.3|dip:DIP-2933N|mint:Q03018|ensemblfungi:YGR098C(gene)|ensemblfungi:YGR098C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006915"(apoptotic process)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR005314(Peptidase C50, separase)|interpro:IPR030397|rcsb pdb:5U1S|rcsb pdb:5U1T|reactome:R-SCE-2467813	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Fig 2A, 2C, 2E|comment:Interaction occurs in M-phase.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/07	2014/10/16	rogid:UMTGDO9alhQOMP7ZXNTEDs/ZB68559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:A2039A474B0979AE|rigid:P9BoRao1CPMEBwHiF6cIoK6IpjM	false	myc tag:c-c	protein a tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32562	uniprotkb:Q08581	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rahal et al. (2008)	pubmed:18927509|imex:IM-19190	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2133654|imex:IM-19190-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Fig 2B, 2D, 2F|comment:Interaction occurs in M-phase.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/07	2014/10/16	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292	intact-crc:A098DDF0CEE4325B|rigid:r9a4W2X4TN1NDjMpjcpMQucJvGg	false	protein a tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00684	uniprotkb:P32562	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Rahal et al. (2008)	pubmed:18927509|imex:IM-19190	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2133674|imex:IM-19190-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	crc64:4EB3985DFA3FD823	crc64:B5A25F1BBBEAA3DC	figure legend:Fig 3A, 3B, 3C|comment:Interaction occurs in M-phase.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/07	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:11F9572BD46F9A9A|rigid:onqpF8grIwx/IIoxycjvx8jFC+A	false	ha tag:n-n	protein a tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00684	uniprotkb:P32562	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0096"(pull down)	Rahal et al. (2008)	pubmed:18927509|imex:IM-19190	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2133689|imex:IM-19190-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	crc64:4EB3985DFA3FD823	crc64:B5A25F1BBBEAA3DC	figure legend:Fig 4A, 4B, 4D, 4E, 4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/07	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:D450EF895BA43C7A|rigid:onqpF8grIwx/IIoxycjvx8jFC+A	false	sufficient binding region:1-374|ha tag:c-c	sufficient binding region:357-705|mutation decreasing interaction:641-641,643-643|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)