#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8080746|mint:MINT-7304806|imex:IM-13784-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7304809(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7304808(identity) - comment:mint - figure legend:F1 T1|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:A1DE88C3F2E84F64|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7304816) binding-associated region:74-163(MINT-7304811) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080774|mint:MINT-7305170|imex:IM-13784-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305178(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305173(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:86240AB51828B8BE|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7305179)|tag:?-?(MINT-7305287) tag:?-?(MINT-7305290)|mutation disrupting interaction:233-233(MINT-7305292)|binding-associated region:74-163(MINT-7305174) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080850|mint:MINT-7305333|imex:IM-13784-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305344(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305335(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:FEE9133AD3113967|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false tag:?-?(MINT-7305347)|binding-associated region:1-217(MINT-7305345) mutation decreasing interaction:157-157(MINT-7305336)|tag:?-?(MINT-7305341)|binding-associated region:74-163(MINT-7305338) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080803|mint:MINT-7305300|imex:IM-13784-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305302(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305308(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:32A13B79FF493EF6|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7305305)|tag:?-?(MINT-7305303) binding-associated region:74-163(MINT-7305313)|mutation decreasing interaction:233-233(MINT-7305309)|tag:?-?(MINT-7305311) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080908|mint:MINT-7305387|imex:IM-13784-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305398(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305389(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:82A0843227EDC7C1|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7305399)|tag:?-?(MINT-7305401) mutation decreasing interaction:221-221(MINT-7305390)|tag:?-?(MINT-7305395)|binding-associated region:74-163(MINT-7305392) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080937|mint:MINT-7305408|imex:IM-13784-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305410(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305416(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:B6118D40CA433628|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7305413)|tag:?-?(MINT-7305411) tag:?-?(MINT-7305419)|mutation disrupting interaction:168-168(MINT-7305417)|binding-associated region:74-163(MINT-7305421) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080879|mint:MINT-7305354|imex:IM-13784-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305356(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305362(identity) - comment:mint - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:FEE91339FFC192E3|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7305359)|tag:?-?(MINT-7305357) tag:?-?(MINT-7305363)|binding-associated region:74-163(MINT-7305365)|mutation disrupting interaction:157-157(MINT-7305368) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9SE33 uniprotkb:Q9SUR9 intact:EBI-1781969|uniprotkb:Q9FLI9|ensemblplants:AT5G51700.1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:rar1_arath(display_long)|uniprotkb:RAR1(gene name)|psi-mi:RAR1(display_short)|uniprotkb:At5g51700(locus name)|uniprotkb:PBS2(gene name synonym)|uniprotkb:RPR2(gene name synonym)|uniprotkb:AtRAR1(gene name synonym)|uniprotkb:CHORD domain-containing protein RAR1(gene name synonym)|uniprotkb:Protein PPHB SUSCEPTIBLE 2(gene name synonym)|uniprotkb:Protein REQUIRED FOR MLA12 RESISTANCE 1(gene name synonym)|uniprotkb:MIO24.17(orf name) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8080966|mint:MINT-7305428|imex:IM-13784-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_568762.6|dip:DIP-41228N|mint:Q9SE33|ensemblplants:AT5G51700(gene)|ensemblplants:AT5G51700.1(transcript)|go:"GO:0002679"(respiratory burst involved in defense response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009626"(plant-type hypersensitive response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR007051(CHORD)|interpro:IPR043316|rcsb pdb:2XCM|mint:MINT-7305430(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305439(identity) - - - figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/11/25 2014/10/16 rogid:3pbUPad+EHPL9pU0ZSuba5DjcLo3702 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:9DC905EBE682973B|rigid:aRkQcr12d4oOY5lWzdbpp2cPgeM false tag:?-?(MINT-7305436) binding-associated region:74-163(MINT-7305440)|tag:?-?(MINT-7305442) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63208 uniprotkb:Q13616 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8080997|mint:MINT-7305060|imex:IM-13784-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305065(identity) refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N|mint:MINT-7305063(identity) - - - figure legend:F3E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:509EBAF45C3C9736|rigid:8VWOSqlWbqfirak4fCg2JKiEE+Y false - his tag:?-?(MINT-7305070) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63208 uniprotkb:Q9Y2Z0-2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-10768076|ensembl:ENSP00000308067 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081012|mint:MINT-7305074|imex:IM-13784-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305077(identity) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)|mint:MINT-7305079(identity) - - - figure legend:F3B F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2015/04/29 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 intact-crc:C1022671F90AADEB|rigid:bsCqZOiqlpYdi3p2MYgTaiQhXx0 false - mutation increasing interaction:145-145(MINT-7305087)|glutathione s tranferase tag:?-?(MINT-7305085) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63208 uniprotkb:Q9Y2Z0-2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-10768076|ensembl:ENSP00000308067 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8081032|mint:MINT-7305092|imex:IM-13784-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305100(identity) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)|mint:MINT-7305094(identity) - - - figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2015/04/29 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 intact-crc:CDD7A49AA7E70288|rigid:ISyugDWIWOHvX+vYfBePHHPZGQY false glutathione s tranferase tag:?-?(MINT-7305124) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63208 uniprotkb:Q13309 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-456291|uniprotkb:Q8TDZ0|uniprotkb:Q8TDZ1|uniprotkb:Q9BV69|ensembl:ENSP00000274255|uniprotkb:A8K5E0|uniprotkb:B4DJT4 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:skp2_human(display_long)|uniprotkb:F-box protein Skp2(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p45(gene name synonym)|uniprotkb:p45skp2(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 1(gene name synonym)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)|uniprotkb:FBXL1(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8081032|mint:MINT-7305092|imex:IM-13784-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305100(identity) ensembl:ENSG00000145604(gene)|ensembl:ENST00000274255(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|rcsb pdb:2ASS|rcsb pdb:2AST|interpro:IPR032675|rcsb pdb:7B5L|interpro:IPR036047|mint:Q13309|rcsb pdb:1FQV|rcsb pdb:7B5M|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|refseq:NP_005974.2|refseq:NP_116026.1|refseq:NP_001230049.1|dip:DIP-17011N|rcsb pdb:7B5R|reactome:R-HSA-174178|reactome:R-HSA-187577|reactome:R-HSA-5689880|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9687136|reactome:R-HSA-9708530|reactome:R-HSA-983168|mint:MINT-7305103(identity) - - - figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2015/04/29 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:VABxcX3qu0Yr6eRNYINqvAPhPMc9606 intact-crc:CDD7A49AA7E70288|rigid:ISyugDWIWOHvX+vYfBePHHPZGQY false glutathione s tranferase tag:?-?(MINT-7305124) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P08238 uniprotkb:Q9Y2Z0-2 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 intact:EBI-10768076|ensembl:ENSP00000308067 psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081098|mint:MINT-7305143|imex:IM-13784-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|mint:MINT-7305145(identity) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)|mint:MINT-7305149(identity) - - - figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2015/04/29 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 intact-crc:FEAE4522E2200F76|rigid:PBoVrXpR6zCN95c7CIjK8ltguiQ false his tag:?-?(MINT-7305146)|mutation decreasing interaction:145-145(MINT-7305154) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P63208 uniprotkb:P08238 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081065|mint:MINT-7305127|imex:IM-13784-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305129(identity) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|mint:MINT-7305133(identity) - - - figure legend:F3A|comment:homomint|comment:mint|comment:Interaction increase when also Sgt1 is present.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:4C0762D52649C3F9|rigid:sgSdgnZNfaAlSTUGF4SEruyqn9c false - his tag:?-?(MINT-7305137) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13309 uniprotkb:P63208 intact:EBI-456291|uniprotkb:Q8TDZ0|uniprotkb:Q8TDZ1|uniprotkb:Q9BV69|ensembl:ENSP00000274255|uniprotkb:A8K5E0|uniprotkb:B4DJT4 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:skp2_human(display_long)|uniprotkb:F-box protein Skp2(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p45(gene name synonym)|uniprotkb:p45skp2(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 1(gene name synonym)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)|uniprotkb:FBXL1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081050|mint:MINT-7305110|imex:IM-13784-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145604(gene)|ensembl:ENST00000274255(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|rcsb pdb:2ASS|rcsb pdb:2AST|interpro:IPR032675|rcsb pdb:7B5L|interpro:IPR036047|mint:Q13309|rcsb pdb:1FQV|rcsb pdb:7B5M|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|refseq:NP_005974.2|refseq:NP_116026.1|refseq:NP_001230049.1|dip:DIP-17011N|rcsb pdb:7B5R|reactome:R-HSA-174178|reactome:R-HSA-187577|reactome:R-HSA-5689880|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9687136|reactome:R-HSA-9708530|reactome:R-HSA-983168|mint:MINT-7305112(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305114(identity) - - - figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:VABxcX3qu0Yr6eRNYINqvAPhPMc9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:DC65C85A9346BCF5|rigid:KqnEUZ3NhZKxMfpBk28MYeP54NY false - glutathione s tranferase tag:?-?(MINT-7305121) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0Q0I7 uniprotkb:Q9SUR9 intact:EBI-8081141|intact:MINT-6822829|ensemblplants:TraesCS5B02G258900.2|ensemblplants:TraesCS5D02G268000.1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q0q0i7_wheat(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:Hsp90.3-B1(gene name synonym)|uniprotkb:Hsp90.3-D1(gene name synonym)|uniprotkb:HSP90-2(gene name)|psi-mi:HSP90-2(display_short)|uniprotkb:HSP90-1(gene name synonym) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4565(wheat)|taxid:4565("Triticum aestivum (Wheat)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081136|mint:MINT-7305184|imex:IM-13784-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q0Q0I7|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005886"(plasma membrane)|ensemblplants:TraesCS5B02G258900(gene)|ensemblplants:TraesCS5B02G258900.2(transcript)|ensemblplants:TraesCS5D02G268000(gene)|ensemblplants:TraesCS5D02G268000.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|mint:MINT-7305187(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305191(identity) - comment:mint - figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:EZjWHW8v4MNUI114APexUIu6E2o4565 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:01B4F8751402CE91|rigid:r/GpE9DVapQ3Y53FWvDz08CWBs4 false mutation decreasing interaction:89-89(MINT-7305208)|his tag:?-?(MINT-7305206) glutathione s tranferase tag:?-?(MINT-7305212) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q0Q0I7 uniprotkb:Q9SUR9 intact:EBI-8081141|intact:MINT-6822829|ensemblplants:TraesCS5B02G258900.2|ensemblplants:TraesCS5D02G268000.1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q0q0i7_wheat(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:Hsp90.3-B1(gene name synonym)|uniprotkb:Hsp90.3-D1(gene name synonym)|uniprotkb:HSP90-2(gene name)|psi-mi:HSP90-2(display_short)|uniprotkb:HSP90-1(gene name synonym) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4565(wheat)|taxid:4565("Triticum aestivum (Wheat)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081175|mint:MINT-7305216|imex:IM-13784-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q0Q0I7|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0005886"(plasma membrane)|ensemblplants:TraesCS5B02G258900(gene)|ensemblplants:TraesCS5B02G258900.2(transcript)|ensemblplants:TraesCS5D02G268000(gene)|ensemblplants:TraesCS5D02G268000.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|mint:MINT-7305218(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7305224(identity) - comment:mint - figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2014/10/16 rogid:EZjWHW8v4MNUI114APexUIu6E2o4565 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:B7C6DC7EA0075A19|rigid:r/GpE9DVapQ3Y53FWvDz08CWBs4 false his tag:?-?(MINT-7305221)|mutation decreasing interaction:92-92(MINT-7305219) glutathione s tranferase tag:?-?(MINT-7305225) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P08238 uniprotkb:Q9Y2Z0-2 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 intact:EBI-10768076|ensembl:ENSP00000308067 psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081117|mint:MINT-7305157|imex:IM-13784-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N|mint:MINT-7305161(identity) ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent)|mint:MINT-7305159(identity) - - - figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/11/25 2015/04/29 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 intact-crc:9CA334028A887AEA|rigid:PBoVrXpR6zCN95c7CIjK8ltguiQ false his tag:?-?(MINT-7305164)|mutation disrupting interaction:145-145(MINT-7305162) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P02829 uniprotkb:Q08446 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-17070|ensemblfungi:YOR057W|uniprotkb:D6W2C0|uniprotkb:E9P8U7 psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:sgt1_yeast(display_long)|uniprotkb:SGT1(gene name)|psi-mi:SGT1(display_short)|uniprotkb:YOR057W(locus name)|uniprotkb:YOR29-08(orf name)|uniprotkb:Suppressor of G2 allele of SKP1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081225|mint:MINT-7304952|imex:IM-13784-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N|mint:MINT-7304955(identity) refseq:NP_014700.1|sgd:S000005583|ensemblfungi:YOR057W(gene)|ensemblfungi:YOR057W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034622"|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044563|rcsb pdb:5AN3|reactome:R-SCE-844456|dip:DIP-1628N|mint:Q08446|mint:MINT-7304954(identity) - crc64:D7C35676D668FB63 crc64:5DE65874BE155552 figure legend:SF1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.1x10^-6(molar) 2009/11/25 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:DJ37U8QHPE7Wi/+kOiEwCg1mxCw559292 intact-crc:BE298A6498C9B5CC|rigid:1aAaFFgSpbPhuSLTi456L8si/cM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7XJ80 uniprotkb:Q9SUR9 intact:EBI-8080730|intact:MINT-7304791|ensemblplants:HORVU.MOREX.r2.5HG0406220.1|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1 intact:EBI-1778186|uniprotkb:Q84LL4|uniprotkb:Q8W515|ensemblplants:AT4G23570.1|ensemblplants:AT4G23570.2 psi-mi:q7xj80_horvu(display_long)|uniprotkb:HSP90(gene name)|psi-mi:HSP90(display_short) psi-mi:sgt1a_arath(display_long)|uniprotkb:SGT1A(gene name)|psi-mi:SGT1A(display_short)|uniprotkb:F9D16.40(orf name)|uniprotkb:At4g23570(locus name)|uniprotkb:Suppressor of G2 allele of SKP1 homolog A(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:4513(horvu)|taxid:4513("Hordeum vulgare (Barley)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081205|mint:MINT-7304925|imex:IM-13784-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR020575|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR036890|interpro:IPR037196|mint:Q7XJ80|ensemblplants:HORVU.MOREX.r2.5HG0406220(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(gene)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1(transcript)|ensemblplants:HORVU.MOREX.r2.5HG0406220.1.mrna1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7304927(identity) refseq:NP_001031704.1|refseq:NP_194088.1|refseq:NP_849429.1|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR007699(SGS)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9SUR9|interpro:IPR044563|ensemblplants:AT4G23570(gene)|ensemblplants:AT4G23570.1(transcript)|ensemblplants:AT4G23570.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006952"(defense response)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051087"(chaperone binding)|go:"GO:0071365"(cellular response to auxin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1900150"(regulation of defense response to fungus)|rcsb pdb:2JKI|rcsb pdb:2XCM|mint:MINT-7304931(identity) - comment:mint - figure legend:SF1|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.3x10^-5(molar) 2009/11/25 2014/10/16 rogid:TLsBHkAS8N/1YtOPTv8hZEMtuUY4513 rogid:NpmqWLGeVVifAoJqJl83hPNBwdc3702 intact-crc:990040E5627BCEF1|rigid:nAy5nFJLWf6fFoJabgzJvbpkJfw false binding-associated region:1-217(MINT-7304928) binding-associated region:74-163(MINT-7304932) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13616 uniprotkb:P63208 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081250|mint:MINT-7305000|imex:IM-13784-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N|mint:MINT-7305005(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7305003(identity) - - - figure legend:SF3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.4x10^-8(molar) 2009/11/25 2014/10/16 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:255B622D485AEA1F|rigid:8VWOSqlWbqfirak4fCg2JKiEE+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y2Z0 uniprotkb:P63208 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Zhang et al. (2008) pubmed:18818696|imex:IM-13784|mint:MINT-7304783|doi:10.1038/emboj.2008.190 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8081237|mint:MINT-7304971|imex:IM-13784-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N|mint:MINT-7304976(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|mint:MINT-7304974(identity) - - - figure legend:SF3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.64x10^-9(molar) 2009/11/25 2015/04/29 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:CE3CC81E21C42768|rigid:SMXgYO6obQ4up6w3hS3sBi2MXq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)