#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P289 uniprotkb:Q9Y3A3 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q9NRL3 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:P67775 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q9P2B4 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:O43815 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q8WZ74 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q9BUL8 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:P30153 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q13033 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P289 uniprotkb:Q14BN4 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476697|imex:IM-20360-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:Supplementary Table 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:E3473DC281738238|rigid:7631YA7sFu72jwPYLdJsJQRXSzg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P67775 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q5VSL9 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9NRL3 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P30153 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9P2B4 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9P289 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9Y3A3 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9BUL8 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476710|imex:IM-20360-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:Supplementary Table S7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:AFC4ED95A02DC16E|rigid:pzxFdKMTSQjJJNPvVe0JsQPd1JA false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:O43815 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476684|imex:IM-20360-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:7037D18312973D6A|rigid:gOIQqTh93/PA1TePqJIonOTHLI8 false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q13033 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476688|imex:IM-20360-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:7F3E40393FD63CBC|rigid:gOIQqTh93/PA1TePqJIonOTHLI8 false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P289 uniprotkb:O43815 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476692|imex:IM-20360-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:15997032AD49F540|rigid:mRz/Axr42sBe35y+y1O0X49zAOc false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P289 uniprotkb:Q13033 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476692|imex:IM-20360-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:15997032AD49F540|rigid:mRz/Axr42sBe35y+y1O0X49zAOc false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q5VSL9 uniprotkb:O43815 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476490|imex:IM-20360-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:2 and supplementary materials|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:7C25EF9306C02CAF|rigid:zn+W5f5yHVx/FsQdTePY8hYdxIY false flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q5VSL9 uniprotkb:P62714 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476490|imex:IM-20360-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N - - - figure legend:2 and supplementary materials|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 intact-crc:7C25EF9306C02CAF|rigid:zn+W5f5yHVx/FsQdTePY8hYdxIY false flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P2B4 uniprotkb:O43815 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476498|imex:IM-20360-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:2 and Supplemental Materials|caution:Antibody cannot discriminate between PPP2CA and PPP2CB hence these have not been added to the interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:DBDC3709B9FF7910|rigid:eAFxWO3mkQdjSlF2Fod4bYvWX8A false flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P289 uniprotkb:Q5VSL9 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476526|imex:IM-20360-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:2 and supplemental material|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:7A72531B3D3B3E67|rigid:mhEH6G6xQYluZlcZN+IMLPY5Kds false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P2B4 uniprotkb:Q9P289 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476534|imex:IM-20360-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:2 and Supplemental Materials|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:94B2A10BA79EA114|rigid:iZdLKoE3lQYI3u1EvX7YGkewxfk false flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:P67775 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476540|imex:IM-20360-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - sample process:endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:1989018F8CECBA9F|rigid:VgT2K5pItUQWN9MCGhhtRVJmZUo false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q13033 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476547|imex:IM-20360-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - sample process:endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:F9097D093BCE1F23|rigid:gOIQqTh93/PA1TePqJIonOTHLI8 false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9Y3A3 uniprotkb:O43815 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476554|imex:IM-20360-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:57490DE8EADA1E9A|rigid:jYoD5BB4oCpjyYiM1ZhODgoEzvk false flag tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q9Y6E0 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476561|imex:IM-20360-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:AE49CBD2BE72B884|rigid:aarWiaOKq0WZdoR39IF6htDd1Kw false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:O00506 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476568|imex:IM-20360-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:F2F647BEF04B3C13|rigid:Xw3qYrXzhLXXSasm9GuPSFYAtqE false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q9BUL8 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476575|imex:IM-20360-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:825A6C8F041E0913|rigid:BiUxD8AakKng6JZSCUODxbrYwCs false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q9Y228 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476582|imex:IM-20360-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 intact-crc:F13AD85875D6E2F1|rigid:tJ83WG7O1uAp/Do++wVIFIEAT/4 false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:Q9P2B4 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476589|imex:IM-20360-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - sample process:O43815 endogenous|figure legend:S6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:44F57B314CE1BC09|rigid:eAFxWO3mkQdjSlF2Fod4bYvWX8A false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O43815 uniprotkb:P30153 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476596|imex:IM-20360-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - sample process:endogenous|figure legend:S3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:680E0CDE0B6DFABE|rigid:FoX4T0NI8I+sn3QZlz1+vqtYPnE false - flag tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9P2B4 uniprotkb:Q9Y3A3 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476603|imex:IM-20360-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - delivery method:Q9Y3A3; Q9P2B4 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:C8491DAEEC297B64|rigid:pwH+g5OLML9jvRBmjEbKV1sAzWI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P2B4 uniprotkb:Q13033 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476612|imex:IM-20360-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - delivery method:Q13033; Q9P2B4 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:60C9DE2FE28EFFF3|rigid:Q5VsWVY2cbxHeHN3Ic390vU44l0 false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P2B4 uniprotkb:Q5VSL9 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476621|imex:IM-20360-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - delivery method:Q5VSL9; Q9P2B4 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:D12E335432E354FF|rigid:8TSANkVwaoLnKBi2OjDHNEeUrlc false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y6E0 uniprotkb:Q9P2B4 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476630|imex:IM-20360-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - delivery method:Q9P2B4; Q9Y6E0 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:D44B163FA7FB55D8|rigid:yQ1C8s0Z7v9ali2cZmDgNNthTJU false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y6E0 uniprotkb:Q9Y228 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476639|imex:IM-20360-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 - - - delivery method:Q9Y228; Q9Y6E0 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 intact-crc:BFEC4205FAF6EDEB|rigid:HWfC1tB3/0/l4YHc1tkEVtBlRtU false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y228 uniprotkb:Q5VSL9 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476648|imex:IM-20360-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - delivery method:Q5VSL9; Q9Y228 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:60F7C2EBB2341217|rigid:rF+E+9654t4Zek2CMH9qIpgRf5M false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13033 uniprotkb:Q9Y228 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476657|imex:IM-20360-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 - - - delivery method:Q9Y228; Q13033 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 intact-crc:D7CCC9C4CE6A6633|rigid:6cWzDrfYfsZsnw76gSpHFbh82pY false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y228 uniprotkb:Q9Y3A3 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476666|imex:IM-20360-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - delivery method:Q9Y3A3; Q9Y228 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:DC6DA0459913FBC9|rigid:lVKx+7gUTaExXhfOSX/cYZX6Dhc false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y228 uniprotkb:Q9BRV8 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2476675|imex:IM-20360-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - delivery method:Q9BRV8; Q9Y228 transient expression|figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:0FD28366500DE050|rigid:n2rvMFdzIOlbOuoSTNCYC5Nz0rM false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P30153 uniprotkb:Q9NRL3 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3|uniprotkb:Q9NRL3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:O43815 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775|uniprotkb:O43815 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13362 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|uniprotkb:Q13362 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q5VSL9 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36|uniprotkb:Q5VSL9 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13136 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500|uniprotkb:Q13136 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9Y3A3 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|uniprotkb:Q9Y3A3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q14738 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N|uniprotkb:Q14738 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9Y3A3 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|uniprotkb:Q9Y3A3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9P2B4 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)|uniprotkb:Q9P2B4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13033 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479208|imex:IM-20360-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript)|uniprotkb:Q13033 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:ECAE711039B863E7|rigid:ulkNpw3f/d9qmI4Ta7IYjUI9NdQ false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P30154 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)|uniprotkb:P30154 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q5VSL9 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36|uniprotkb:Q5VSL9 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13033 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript)|uniprotkb:Q13033 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13362 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|uniprotkb:Q13362 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P78318 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|uniprotkb:P78318 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13136 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500|uniprotkb:Q13136 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O75145 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1763225|uniprotkb:Q9H8B5|uniprotkb:Q9UEW4|uniprotkb:A8K142|uniprotkb:Q3MJA0|ensembl:ENSP00000335614 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:lipa3_human(display_long)|uniprotkb:PPFIA3(gene name)|psi-mi:PPFIA3(display_short)|uniprotkb:KIAA0654(gene name synonym)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003651.1|ensembl:ENSG00000177380(gene)|ensembl:ENST00000334186(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098875"(epididymosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030440|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|refseq:XP_016882896.1|uniprotkb:O75145 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:zQZLKleQyjA1RTbZN5woc0Ywvh09606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9Y3A3 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|uniprotkb:Q9Y3A3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q16537 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1|uniprotkb:Q16537 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q14738 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N|uniprotkb:Q14738 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9NRL3 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3|uniprotkb:Q9NRL3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9P2B4 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)|uniprotkb:Q9P2B4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P30153 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O43815 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775|uniprotkb:O43815 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P63151 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N|uniprotkb:P63151 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P78371 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P17987 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479253|imex:IM-20360-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. Hoever PPP2CA was used as bait in these studies|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:7ABB3668C413B650|rigid:6wMavnDmLfYTAeKjWsK14rZMqz4 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P49368 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:O43815 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775|uniprotkb:O43815 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P17987 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q14738 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N|uniprotkb:Q14738 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P63151 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N|uniprotkb:P63151 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P50990 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P78318 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|uniprotkb:P78318 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q9NRL3 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3|uniprotkb:Q9NRL3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P30153 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P48643 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q99832 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:O95684 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1266334|uniprotkb:Q49AI0|uniprotkb:Q5R3F6|uniprotkb:Q96EW1|uniprotkb:A8K1D1|uniprotkb:B2R705|ensembl:ENSP00000355812 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:cep43_human(display_long)|uniprotkb:CEP43(gene name)|psi-mi:CEP43(display_short)|uniprotkb:FGFR1 oncogene partner(gene name synonym)|uniprotkb:FGFR1OP(gene name synonym)|uniprotkb:FOP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_008976.1|refseq:NP_919410.1|ensembl:ENSG00000213066(gene)|ensembl:ENST00000366847(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR018993|rcsb pdb:2D68|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518|uniprotkb:O95684 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:AcqOicx3UulQVfNzo6X0XyfExcc9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q8WZ74 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770|uniprotkb:Q8WZ74 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P78371 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q9P2B4 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)|uniprotkb:Q9P2B4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q13033 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript)|uniprotkb:Q13033 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q9Y3A3 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|uniprotkb:Q9Y3A3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P40227 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:Q5VSL9 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36|uniprotkb:Q5VSL9 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P62714 uniprotkb:P50991 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479316|imex:IM-20360-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies. However PPP2CB was used as bait in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:A96C191302C2F52C|rigid:17qJDo0unBnR0iZSYIWJ1FnnHDE false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:Q99832 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P50990 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P30154 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)|uniprotkb:P30154 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P50991 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P30153 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P48643 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P78371 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P49368 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P40227 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y2T4 uniprotkb:P17987 intact:EBI-1774058|uniprotkb:Q9H3G7|uniprotkb:A8MSY7|uniprotkb:Q7Z4V7|uniprotkb:Q8NEC4|uniprotkb:B7Z3Y1|ensembl:ENSP00000372042 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:2abg_human(display_long)|uniprotkb:PPP2R2C(gene name)|psi-mi:PPP2R2C(display_short)|uniprotkb:PP2A subunit B isoform gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-gamma(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-gamma(gene name synonym)|uniprotkb:IMYPNO1(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-gamma(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479382|imex:IM-20360-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193925.1|refseq:NP_870991.1|refseq:NP_001193923.1|refseq:NP_001193924.1|refseq:NP_065149.2|ensembl:ENSG00000074211(gene)|ensembl:ENST00000382599(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:cJj+2y6EJdczJD6SnOBRa2hl3ys9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:3BF880748C6FEAFF|rigid:ON6xeTI6Pzsb9bcVagkKbe4ptF8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15172 uniprotkb:P30154 intact:EBI-641666|uniprotkb:Q2NL72|uniprotkb:Q5VVB2|uniprotkb:Q8TBI9|uniprotkb:B2R6D2|uniprotkb:D3DT99|uniprotkb:B7Z7L2|ensembl:ENSP00000261461 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:2a5a_human(display_long)|uniprotkb:PP2A B subunit isoform B'-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-alpha(gene name synonym)|uniprotkb:PPP2R5A(gene name)|psi-mi:PPP2R5A(display_short) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479424|imex:IM-20360-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186685.1|refseq:NP_006234.1|dip:DIP-459N|reactome:R-HSA-9648025|reactome:R-HSA-68877|ensembl:ENSG00000066027(gene)|ensembl:ENST00000261461(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090219"(negative regulation of lipid kinase activity)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15172|rcsb pdb:6NTS|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-5675221|reactome:R-HSA-6811558 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)|uniprotkb:P30154 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:DpFpGFjwzJej//cr7ciShgzJpCE9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:B61FC25CEDF1716F|rigid:k3FMWcnxlHNVW1x30PtRfDq1bNU false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15172 uniprotkb:P30153 intact:EBI-641666|uniprotkb:Q2NL72|uniprotkb:Q5VVB2|uniprotkb:Q8TBI9|uniprotkb:B2R6D2|uniprotkb:D3DT99|uniprotkb:B7Z7L2|ensembl:ENSP00000261461 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:2a5a_human(display_long)|uniprotkb:PP2A B subunit isoform B'-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-alpha(gene name synonym)|uniprotkb:PPP2R5A(gene name)|psi-mi:PPP2R5A(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479424|imex:IM-20360-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186685.1|refseq:NP_006234.1|dip:DIP-459N|reactome:R-HSA-9648025|reactome:R-HSA-68877|ensembl:ENSG00000066027(gene)|ensembl:ENST00000261461(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090219"(negative regulation of lipid kinase activity)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15172|rcsb pdb:6NTS|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-5675221|reactome:R-HSA-6811558 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:DpFpGFjwzJej//cr7ciShgzJpCE9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:B61FC25CEDF1716F|rigid:k3FMWcnxlHNVW1x30PtRfDq1bNU false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:O43815 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775|uniprotkb:O43815 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q96FJ2 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|uniprotkb:Q96FJ2 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P17987 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q13033 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript)|uniprotkb:Q13033 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P48643 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q9BRV8 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding)|uniprotkb:Q9BRV8 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P50991 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q99832 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P63167 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P30154 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)|uniprotkb:P30154 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P50990 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q5VSL9 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36|uniprotkb:Q5VSL9 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P40227 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q9P2B4 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)|uniprotkb:Q9P2B4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P78371 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P49368 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:Q9Y3A3 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|uniprotkb:Q9Y3A3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NRL3 uniprotkb:P30153 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479446|imex:IM-20360-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:CAA36306D74BC17A|rigid:lw/bbaynWEvPdnkosNJwEQJOb6g false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9ULQ0 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|uniprotkb:Q9ULQ0 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q13033 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript)|uniprotkb:Q13033 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9BRV8 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding)|uniprotkb:Q9BRV8 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9P2B4 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium)|uniprotkb:Q9P2B4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9NRL3 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3|uniprotkb:Q9NRL3 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q5VSL9 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36|uniprotkb:Q5VSL9 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P63167 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:O43815 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775|uniprotkb:O43815 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q8WZ74 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770|uniprotkb:Q8WZ74 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P30154 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene)|uniprotkb:P30154 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q14BN4 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|uniprotkb:Q14BN4 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P30153 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479515|imex:IM-20360-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|uniprotkb:P30153 - - - figure legend:Supplementary table S5|caution:The proteins PP2Ac a and PP2Ac b that formed part of the complex could not be distinguished by Mass Spectroscopy in these studies.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:24D690909A82981E|rigid:5H2YfaS3k4tmk86hv3DNJe2uUs8 false tandem tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13362 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q14BN4 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:P63151 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9P2B4 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:O75334 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1105129|ensembl:ENSP00000450337|uniprotkb:B3KXA0|uniprotkb:B7ZKZ5|uniprotkb:F8VP68|uniprotkb:Q2M3G8|uniprotkb:B3KVT5|uniprotkb:B7Z2A6|uniprotkb:B7Z3U9|uniprotkb:B7Z663|uniprotkb:E7ERB8|uniprotkb:E7ETG6 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:lipa2_human(display_long)|uniprotkb:PPFIA2(gene name)|psi-mi:PPFIA2(display_short)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_003616.2|ensembl:ENSG00000139220(gene)|ensembl:ENST00000549396(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099181"(structural constituent of presynapse)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030441|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:O75334|rcsb pdb:3TAC|rcsb pdb:3TAD|rcsb pdb:6IUH|rcsb pdb:7D2E|rcsb pdb:7D2G|rcsb pdb:7D2H|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|refseq:NP_001207403.1|refseq:NP_001207404.1|refseq:NP_001207405.1|refseq:NP_001207406.1|refseq:NP_001207407.1|refseq:NP_001207408.1|refseq:NP_001207409.1|refseq:XP_016875569.1|refseq:XP_016875571.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:JWcUe5GLHo/JyakmiC91TuspElU9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q66LE6 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9Y570 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13136 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:P30154 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13362 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13033 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:P67775 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q16537 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q15173 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1369497|uniprotkb:Q13853|ensembl:ENSP00000164133 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5b_human(display_long)|uniprotkb:PPP2R5B(gene name)|psi-mi:PPP2R5B(display_short)|uniprotkb:PP2A B subunit isoform B'-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_006235.1|ensembl:ENSG00000068971(gene)|ensembl:ENST00000164133(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15173|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-381038|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:aYC6Y4axPUXmrHoGUp7NMQP4p0Q9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q5VSL9 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q15172 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-641666|uniprotkb:Q2NL72|uniprotkb:Q5VVB2|uniprotkb:Q8TBI9|uniprotkb:B2R6D2|uniprotkb:D3DT99|uniprotkb:B7Z7L2|ensembl:ENSP00000261461 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5a_human(display_long)|uniprotkb:PP2A B subunit isoform B'-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-alpha(gene name synonym)|uniprotkb:PPP2R5A(gene name)|psi-mi:PPP2R5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001186685.1|refseq:NP_006234.1|dip:DIP-459N|reactome:R-HSA-9648025|reactome:R-HSA-68877|ensembl:ENSG00000066027(gene)|ensembl:ENST00000261461(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090219"(negative regulation of lipid kinase activity)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15172|rcsb pdb:6NTS|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-5675221|reactome:R-HSA-6811558 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:DpFpGFjwzJej//cr7ciShgzJpCE9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:O43815 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q14738 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9NRL3 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q9Y5P8 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-2479826|intact:EBI-28984956|ensembl:ENSP00000375080|uniprotkb:Q6P4G9|uniprotkb:Q7RTT1|uniprotkb:Q96H01 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:p2r3b_human(display_long)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000167393(gene)|ensembl:ENST00000390665(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR041534|mint:Q9Y5P8|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4MEW|reactome:R-HSA-113501|reactome:R-HSA-69231|reactome:R-HSA-69273|go:"GO:0005654"(nucleoplasm)|refseq:NP_037371.2|ensembl:ENSP00000375080 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:zl5NREjuW2ahdojQSDcqWYJR92g9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P30153 uniprotkb:Q13033 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479833|imex:IM-20360-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:3EDD15A167903959|rigid:wNNvpVqGC8wDMSeG2RPFdIQocnA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P78318 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O75145 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1763225|uniprotkb:Q9H8B5|uniprotkb:Q9UEW4|uniprotkb:A8K142|uniprotkb:Q3MJA0|ensembl:ENSP00000335614 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:lipa3_human(display_long)|uniprotkb:PPFIA3(gene name)|psi-mi:PPFIA3(display_short)|uniprotkb:KIAA0654(gene name synonym)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003651.1|ensembl:ENSG00000177380(gene)|ensembl:ENST00000334186(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098875"(epididymosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030440|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|refseq:XP_016882896.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:zQZLKleQyjA1RTbZN5woc0Ywvh09606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13136 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O95684 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1266334|uniprotkb:Q49AI0|uniprotkb:Q5R3F6|uniprotkb:Q96EW1|uniprotkb:A8K1D1|uniprotkb:B2R705|ensembl:ENSP00000355812 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:cep43_human(display_long)|uniprotkb:CEP43(gene name)|psi-mi:CEP43(display_short)|uniprotkb:FGFR1 oncogene partner(gene name synonym)|uniprotkb:FGFR1OP(gene name synonym)|uniprotkb:FOP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_008976.1|refseq:NP_919410.1|ensembl:ENSG00000213066(gene)|ensembl:ENST00000366847(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR018993|rcsb pdb:2D68|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:AcqOicx3UulQVfNzo6X0XyfExcc9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9Y5P8 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-2479826|intact:EBI-28984956|ensembl:ENSP00000375080|uniprotkb:Q6P4G9|uniprotkb:Q7RTT1|uniprotkb:Q96H01 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:p2r3b_human(display_long)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000167393(gene)|ensembl:ENST00000390665(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR041534|mint:Q9Y5P8|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4MEW|reactome:R-HSA-113501|reactome:R-HSA-69231|reactome:R-HSA-69273|go:"GO:0005654"(nucleoplasm)|refseq:NP_037371.2|ensembl:ENSP00000375080 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:zl5NREjuW2ahdojQSDcqWYJR92g9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9P2B4 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P48643 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q8WZ74 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9Y3A3 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q5VSL9 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q66LE6 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-717262|uniprotkb:A8KAK0|uniprotkb:Q5SQJ2|uniprotkb:Q9P1Y7|intact:EBI-2556023|ensembl:ENSP00000399970 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2abd_human(display_long)|uniprotkb:PP2A subunit B isoform delta(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-delta(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-delta(gene name synonym)|uniprotkb:PPP2R2D(gene name)|psi-mi:PPP2R2D(display_short)|uniprotkb:KIAA1541(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_060931.2|ensembl:ENSG00000175470(gene)|ensembl:ENST00000455566(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005829"(cytosol)|go:"GO:0010458"(exit from mitosis)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q66LE6|reactome:R-HSA-2465910|refseq:NP_001278239.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:rqczFHaYgyv+qEbwD4SjcdXrjR49606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P30153 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9NRL3 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P50991 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q99832 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P63151 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P78371 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q9Y570 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P49368 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q15173 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1369497|uniprotkb:Q13853|ensembl:ENSP00000164133 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5b_human(display_long)|uniprotkb:PPP2R5B(gene name)|psi-mi:PPP2R5B(display_short)|uniprotkb:PP2A B subunit isoform B'-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006235.1|ensembl:ENSG00000068971(gene)|ensembl:ENST00000164133(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15173|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-381038|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:aYC6Y4axPUXmrHoGUp7NMQP4p0Q9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q16537 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q15172 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-641666|uniprotkb:Q2NL72|uniprotkb:Q5VVB2|uniprotkb:Q8TBI9|uniprotkb:B2R6D2|uniprotkb:D3DT99|uniprotkb:B7Z7L2|ensembl:ENSP00000261461 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5a_human(display_long)|uniprotkb:PP2A B subunit isoform B'-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-alpha(gene name synonym)|uniprotkb:PPP2R5A(gene name)|psi-mi:PPP2R5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001186685.1|refseq:NP_006234.1|dip:DIP-459N|reactome:R-HSA-9648025|reactome:R-HSA-68877|ensembl:ENSG00000066027(gene)|ensembl:ENST00000261461(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090219"(negative regulation of lipid kinase activity)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15172|rcsb pdb:6NTS|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-5675221|reactome:R-HSA-6811558 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:DpFpGFjwzJej//cr7ciShgzJpCE9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P50990 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q14BN4 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13362 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O75334 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1105129|ensembl:ENSP00000450337|uniprotkb:B3KXA0|uniprotkb:B7ZKZ5|uniprotkb:F8VP68|uniprotkb:Q2M3G8|uniprotkb:B3KVT5|uniprotkb:B7Z2A6|uniprotkb:B7Z3U9|uniprotkb:B7Z663|uniprotkb:E7ERB8|uniprotkb:E7ETG6 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:lipa2_human(display_long)|uniprotkb:PPFIA2(gene name)|psi-mi:PPFIA2(display_short)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003616.2|ensembl:ENSG00000139220(gene)|ensembl:ENST00000549396(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099181"(structural constituent of presynapse)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030441|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:O75334|rcsb pdb:3TAC|rcsb pdb:3TAD|rcsb pdb:6IUH|rcsb pdb:7D2E|rcsb pdb:7D2G|rcsb pdb:7D2H|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|refseq:NP_001207403.1|refseq:NP_001207404.1|refseq:NP_001207405.1|refseq:NP_001207406.1|refseq:NP_001207407.1|refseq:NP_001207408.1|refseq:NP_001207409.1|refseq:XP_016875569.1|refseq:XP_016875571.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:JWcUe5GLHo/JyakmiC91TuspElU9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P40227 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q13033 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:O43815 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P17987 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:Q14738 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P67775 uniprotkb:P30154 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479884|imex:IM-20360-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:20B9ED1DB6D59D69|rigid:XxiGewM/ffaewaq0ceJRylguiMM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P49368 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:O00506 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9Y6E0 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q99832 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9NVK5 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P67775 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P17987 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P48643 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q5VSL9 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9BRV8 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q13033 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9ULQ0 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9P289 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P50990 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9BRV8 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9BUL8 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P40227 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P50991 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q14BN4 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q92526 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-2479962|ensembl:ENSP00000327191|uniprotkb:Q8TC34|uniprotkb:B4DYB0|uniprotkb:B4DX20 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpw_human(display_long)|uniprotkb:CCT6B(gene name)|psi-mi:CCT6B(display_short)|uniprotkb:CCT-zeta-2(gene name synonym)|uniprotkb:TCP-1-zeta-like(gene name synonym)|uniprotkb:CCT-zeta-like(gene name synonym)|uniprotkb:Testis-specific Tcp20(gene name synonym)|uniprotkb:Testis-specific protein TSA303(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|ensembl:ENSG00000132141(gene)|ensembl:ENST00000314144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|refseq:NP_001180458.1|refseq:NP_001180459.1|refseq:NP_006575.2|dip:DIP-53269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:VsftnWywz8pwjvqMpE33d9z3bY09606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q8WZ74 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9NRL3 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P78371 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9P2B4 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P30154 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q13033 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q14BN4 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:Q9Y3A3 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O55106 uniprotkb:P30153 intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2479967|imex:IM-20360-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:2F4086F17395ADB6|rigid:C4MI5DydJnRtaVEN8h/Py4cycSM false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9NRL3 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P49368 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P67775 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P50991 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q5VSL9 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q14BN4 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q8WZ74 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P50990 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:O00506 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q99832 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P40227 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9Y6E0 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P78371 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q13033 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P17987 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9P2B4 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:O43815 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9Y3A3 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9BUL8 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9NVK5 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9P289 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q14BN4 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9ULQ0 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:Q9BRV8 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P30154 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P30153 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q13033 uniprotkb:P48643 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480031|imex:IM-20360-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:EC13BCBE28CBD551|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P30153 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P40227 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9BUL8 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q13033 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q14BN4 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q5VSL9 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9Y6E0 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q99832 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P48643 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:O00506 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P17987 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9NRL3 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P30154 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9ULQ0 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q92526 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-2479962|ensembl:ENSP00000327191|uniprotkb:Q8TC34|uniprotkb:B4DYB0|uniprotkb:B4DX20 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpw_human(display_long)|uniprotkb:CCT6B(gene name)|psi-mi:CCT6B(display_short)|uniprotkb:CCT-zeta-2(gene name synonym)|uniprotkb:TCP-1-zeta-like(gene name synonym)|uniprotkb:CCT-zeta-like(gene name synonym)|uniprotkb:Testis-specific Tcp20(gene name synonym)|uniprotkb:Testis-specific protein TSA303(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|ensembl:ENSG00000132141(gene)|ensembl:ENST00000314144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|refseq:NP_001180458.1|refseq:NP_001180459.1|refseq:NP_006575.2|dip:DIP-53269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:VsftnWywz8pwjvqMpE33d9z3bY09606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P49368 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9BRV8 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9P2B4 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P67775 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q13033 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P78371 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9NVK5 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9P289 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:P50990 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q8WZ74 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:O43815 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y3A3 uniprotkb:Q9BRV8 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480091|imex:IM-20360-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:41715DF06352E941|rigid:eNvn0nwTpU88ByqPsI3MK30CqsY false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9BUL8 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q13033 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:P30153 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:P30154 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9P2B4 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:O00506 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9P289 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9Y3A3 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9NRL3 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9Y6E0 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q14BN4 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9BRV8 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9ULQ0 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:O43815 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:Q9NVK5 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q5VSL9 uniprotkb:P67775 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480151|imex:IM-20360-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:1188E89A7DB0E973|rigid:TYFPAkblrxDjUnwqm7mvipZ+jDU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9P289 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q13033 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:O00506 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9BUL8 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9NRL3 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:P67775 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q13033 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9Y6E0 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q5VSL9 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:O43815 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9Y3A3 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:P30154 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:P30153 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9P2B4 uniprotkb:Q9ULQ0 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480193|imex:IM-20360-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:B9B68C3B2BD19C90|rigid:x+7YpBQ+43tAhxfFhOYNfQJF7u4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9Y6E0 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P30153 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:O00506 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P40227 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:O43815 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P50990 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9Y3A3 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P67775 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P78371 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P17987 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q13033 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9P289 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P30154 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q5VSL9 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P49368 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9BUL8 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9NRL3 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9P2B4 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:Q9ULQ0 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8WZ74 uniprotkb:P48643 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480227|imex:IM-20360-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:1B25DE65D42D77B4|rigid:FzpxeUHxFPjskBOWNoOlbaHX1Ns false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9BRV8 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:P30153 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9P2B4 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q14BN4 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q5VSL9 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:O00506 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9BRV8 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9P289 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q13033 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q8WZ74 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9NRL3 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:O43815 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9Y6E0 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9NVK5 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q9Y3A3 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q14BN4 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:Q13033 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:P30154 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BUL8 uniprotkb:P67775 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480275|imex:IM-20360-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:1ECB6739E4046F08|rigid:jyvlwA3YnCQIib+OTMxTKcDz9iU false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:P30153 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q8WZ74 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q14BN4 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:O00506 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9NVK5 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:O43815 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9P2B4 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9ULQ0 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q13033 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:P30154 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9BRV8 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q5VSL9 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9Y6E0 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9Y3A3 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9BUL8 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:P67775 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JT2 uniprotkb:Q9NRL3 intact:EBI-2476505|ensembl:ENSMUSP00000033444 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:stk26_mouse(display_long)|uniprotkb:Stk26(gene name)|psi-mi:Stk26(display_short)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Mst4(gene name synonym)|uniprotkb:STE20-like kinase MST4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MST4(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480319|imex:IM-20360-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|ensembl:ENSMUSG00000031112(gene)|ensembl:ENSMUST00000033444(transcript)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|reactome:R-MMU-111465|refseq:NP_598490.1|refseq:NP_001300673.1 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:Qs5urCmDhJ3cBZkxiPYp+dDbMQ810090 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:D198AF6460BFC2EA|rigid:/glBw3dpW2jq9juhquDNzXc9tRs false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P30153 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P50991 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P48643 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P40227 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9Y3A3 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q14BN4 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q8WZ74 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9BRV8 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P50990 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9P289 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q14BN4 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P30154 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:O00506 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q13033 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P67775 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q5VSL9 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9ULQ0 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9NVK5 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:O43815 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q99832 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9P2B4 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9BRV8 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9NRL3 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q13033 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P49368 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P17987 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:P78371 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y6E0 uniprotkb:Q9BUL8 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480365|imex:IM-20360-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:87E5DEB86260E5C4|rigid:574B38LiDrGO+eIpA2cKZ0ke2+o false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q14BN4 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q5VSL9 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9P2B4 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1774273|uniprotkb:Q96B40|uniprotkb:B3KMS5|ensembl:ENSP00000271277 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:ct2nl_human(display_long)|uniprotkb:CTTNBP2NL(gene name)|psi-mi:CTTNBP2NL(display_short)|uniprotkb:KIAA1433(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:XP_011540083.1|refseq:NP_061174.1|ensembl:ENSP00000271277|refseq:XP_016857295.1|ensembl:ENSG00000143079(gene)|ensembl:ENST00000271277(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034763"(negative regulation of transmembrane transport)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR019131|go:"GO:0030027"(lamellipodium) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:4IOUiHNAw5RSokCYTBZVDROR+UY9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9BUL8 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9Y3A3 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:P30154 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9BRV8 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9Y6E0 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q13033 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q8WZ74 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1774260|uniprotkb:O43389|uniprotkb:Q7LG11|uniprotkb:Q9C0A5|intact:EBI-28975424|ensembl:ENSP00000160373 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:cttb2_human(display_long)|uniprotkb:CTTNBP2(gene name)|psi-mi:CTTNBP2(display_short)|uniprotkb:C7orf8(gene name synonym)|uniprotkb:CORTBP2(gene name synonym)|uniprotkb:KIAA1758(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSP00000160373|refseq:NP_219499.1|ensembl:ENSG00000077063(gene)|ensembl:ENST00000160373(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR002110(Ankyrin)|interpro:IPR019131|interpro:IPR020683|interpro:IPR036770 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:c2nhzEGTnUzKWlGu+9TbZ+rEYEo9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:O43815 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:P30153 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9NRL3 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q14BN4 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9P289 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9BRV8 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:P17987 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q13033 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:P67775 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9ULQ0 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00506 uniprotkb:Q9NVK5 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480427|imex:IM-20360-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:45C81BDCF941F95F|rigid:E63cHo8dOrYopgBFfYN1iNbal0E false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9Y3A3 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:P30153 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:P30154 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9BRV8 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9ULQ0 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q14BN4 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:O43815 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9Y6E0 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9NRL3 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9NVK5 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q13033 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q9BUL8 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q13033 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:P67775 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BRV8 uniprotkb:Q5VSL9 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480475|imex:IM-20360-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:09B65D7C439A9195|rigid:TO4uN/nXwVsdfZny1pTygXqrmU4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9Y3A3 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P30154 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-357094|uniprotkb:O75620|uniprotkb:Q8NHV8|uniprotkb:B0YJ69|intact:EBI-2559603|uniprotkb:B4DWW5|uniprotkb:B4DGQ6|uniprotkb:F8W8G1|uniprotkb:A8MY67|uniprotkb:B4DK91|ensembl:ENSP00000437193 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:2aab_human(display_long)|uniprotkb:PPP2R1B(gene name)|psi-mi:PPP2R1B(display_short)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 dip:DIP-36616N|refseq:NP_001171033.1|refseq:NP_001171034.1|refseq:NP_002707.3|refseq:NP_859050.1|refseq:NP_859051.1|ensembl:ENST00000527614(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:P30154|reactome:R-HSA-113501|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|ensembl:ENSG00000137713(gene) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:fYgJ5+zyhLkZTUHV535I4LB+4iw9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9NVK5 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1104764|uniprotkb:Q6R955|uniprotkb:Q8N5L7|uniprotkb:Q9P034|uniprotkb:Q9UFK8|ensembl:ENSP00000229395 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:fgop2_human(display_long)|uniprotkb:FGFR1OP2(gene name)|psi-mi:FGFR1OP2(display_short)|uniprotkb:HSPC123(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000111790(gene)|ensembl:ENST00000229395(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|interpro:IPR008555(Protein of unknown function DUF837)|reactome:R-HSA-1839117|reactome:R-HSA-5655302|refseq:NP_001165358.1|refseq:NP_001165359.1|refseq:NP_056448.1 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:jXd4sql3WIYvX9V2SbahQYPNMOY9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9BRV8 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q13033 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:O43815 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1046642|uniprotkb:Q3KP65|ensembl:ENSP00000263918|uniprotkb:Q53TQ8|uniprotkb:Q9NP38 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strn_human(display_long)|uniprotkb:STRN(gene name)|psi-mi:STRN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_003153.2|ensembl:ENSG00000115808(gene)|ensembl:ENST00000263918(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0014069"(postsynaptic density)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:O43815|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|reactome:R-HSA-9009391|reactome:R-HSA-9673766|interpro:IPR019775 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:SZjVHxPmRxYLTSqSLJo6jiXlzjQ9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9Y6E0 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q5VSL9 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9P289 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-618239|intact:EBI-1774248|uniprotkb:Q8NC04|uniprotkb:Q9BXC3|ensembl:ENSP00000377867|uniprotkb:Q9BXC4|uniprotkb:Q3ZB77|uniprotkb:B2RAU2 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:stk26_human(display_long)|uniprotkb:STK26(gene name)|psi-mi:STK26(display_short)|uniprotkb:MASK(gene name synonym)|uniprotkb:MST3 and SOK1-related kinase(gene name synonym)|uniprotkb:MST4(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase MASK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000134602(gene)|ensembl:ENST00000394334(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035056|rcsb pdb:3GGF|rcsb pdb:3W8I|rcsb pdb:4FZA|rcsb pdb:4FZD|rcsb pdb:4FZF|rcsb pdb:4GEH|rcsb pdb:5XY9|rcsb pdb:5YF4|rcsb pdb:7B36|reactome:R-HSA-111465|interpro:IPR000719(Protein kinase, core)|refseq:NP_001035917.1|refseq:NP_001035918.1|refseq:NP_057626.2|dip:DIP-34049N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:V6BRp2h2O0RdLI1gRobMJKh28cA9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P67775 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q13033 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9BUL8 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:O00506 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9BRV8 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1773646|uniprotkb:Q5TEZ7|uniprotkb:Q5TEZ9|uniprotkb:Q68DZ4|uniprotkb:Q9H778|ensembl:ENSP00000060969 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:sike1_human(display_long)|uniprotkb:SIKE1(gene name)|psi-mi:SIKE1(display_short)|uniprotkb:SIKE(gene name synonym)|uniprotkb:Suppressor of IKK-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001095866.1|refseq:NP_079349.2|ensembl:ENSG00000052723(gene)|ensembl:ENST00000060969(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|interpro:IPR008555(Protein of unknown function DUF837)|rcsb pdb:6AKK|rcsb pdb:6AKL|rcsb pdb:6AKM|reactome:R-HSA-918233|reactome:R-HSA-933541|go:"GO:0031267"(small GTPase binding) - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:IqdMZ/CEYf6b4P+JGL6IZH+YIYM9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P30153 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P17987 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P48643 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P50990 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9ULQ0 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-1774281|uniprotkb:Q8WUZ4|ensembl:ENSP00000249344 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strp2_human(display_long)|uniprotkb:STRIP2(gene name)|psi-mi:STRIP2(display_short)|uniprotkb:FAM40B(gene name synonym)|uniprotkb:KIAA1170(gene name synonym)|uniprotkb:Protein FAM40B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001127808.1|refseq:NP_065755.1|dip:DIP-51635N|ensembl:ENSG00000128578(gene)|ensembl:ENST00000249344(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:w3e2uSAwxlTpCwTLlCTK9pUBhP89606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P63167 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:P49368 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9Y228 uniprotkb:Q9NRL3 intact:EBI-765817|uniprotkb:Q2YDB5|uniprotkb:A6NIU9|uniprotkb:Q4VY06|uniprotkb:Q7Z706|uniprotkb:A1L464|ensembl:ENSP00000355991|ensembl:ENSP00000355992 intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280 psi-mi:t3jam_human(display_long)|uniprotkb:TRAF3-interacting protein 3(gene name synonym)|uniprotkb:TRAF3IP3(gene name)|psi-mi:TRAF3IP3(display_short)|uniprotkb:T3JAM(gene name synonym) psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Goudreault et al. (2009) pubmed:18782753|imex:IM-20360|mint:MINT-8213804 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2480511|imex:IM-20360-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079504.2|refseq:NP_001274683.1|refseq:NP_001307072.1|refseq:NP_001307073.1|ensembl:ENSG00000009790(gene)|ensembl:ENST00000367024(transcript)|ensembl:ENST00000367025(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9Y228 refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3 - - - figure legend:supplementary table S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/11/04 2014/10/16 rogid:KDgxJv66FX+o56QzfysW3BS/tKc9606 rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606 intact-crc:2BECC185ADDB941F|rigid:WzicBcgNwAGLjZGUarabeX+u9y4 false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)