#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-8045102 uniprotkb:Q91YX7 intact:MINT-7385858 intact:EBI-1700 psi-mi:rg27(display_short)|psi-mi:EBI-8045102(display_long) psi-mi:q91yx7_mouse(display_long)|uniprotkb:Rasa1(gene name)|psi-mi:Rasa1(display_short) psi-mi:"MI:0096"(pull down) Pamonsinlapatham et al. (2008) pubmed:18682833|mint:MINT-7215926|doi:10.1371/journal.pone.0002902 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8045098|mint:MINT-7385868 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-7385872(identity) interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000980(SH2 motif)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR023152|interpro:IPR001452(Src homology-3)|interpro:IPR028554|interpro:IPR035652|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:Q91YX7|interpro:IPR039360|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051020"(GTPase binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1990782"(protein tyrosine kinase binding)|mint:MINT-7385870(identity) - comment:mint|no-uniprot-update: - figure legend:f4b|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/17 2014/10/16 rogid:6jx3KLadfY2YTzgZ9c75zX7X9dg-2 rogid:D4nckFkhCy4t+TRC4dDzHvDVwrQ10090 intact-crc:D62E92169C609518|rigid:vYKCDoRYoyZMTebgzN56Z6ahyAM false glutathione s tranferase tag:?-?(MINT-7385873) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) intact:EBI-8045102 uniprotkb:P20936 intact:MINT-7385858 intact:EBI-1026476|uniprotkb:B2R6W3|uniprotkb:Q9UDI1|uniprotkb:B4DTL2|uniprotkb:Q68CU6|ensembl:ENSP00000274376 psi-mi:rg27(display_short)|psi-mi:EBI-8045102(display_long) psi-mi:rasa1_human(display_long)|uniprotkb:Ras p21 protein activator(gene name synonym)|uniprotkb:p120GAP(gene name synonym)|uniprotkb:RASA1(gene name)|psi-mi:RASA1(display_short)|uniprotkb:RASA(gene name synonym)|uniprotkb:GAP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Pamonsinlapatham et al. (2008) pubmed:18682833|mint:MINT-7215926|doi:10.1371/journal.pone.0002902 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8045212|mint:MINT-7385855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-7385860(identity) refseq:NP_002881.1|refseq:NP_072179.1|ensembl:ENSG00000145715(gene)|ensembl:ENST00000274376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051020"(GTPase binding)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028554|interpro:IPR035652|interpro:IPR035841|interpro:IPR035842|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|interpro:IPR039360|mint:P20936|rcsb pdb:1WER|rcsb pdb:1WQ1|rcsb pdb:2GQI|rcsb pdb:2GSB|rcsb pdb:2J05|rcsb pdb:2J06|rcsb pdb:2M51|rcsb pdb:4FSS|rcsb pdb:6PXB|rcsb pdb:6PXC|rcsb pdb:6WAX|rcsb pdb:6WAY|reactome:R-HSA-186763|reactome:R-HSA-3928662|reactome:R-HSA-5218921|reactome:R-HSA-5658442|reactome:R-HSA-8849471|ensembl:ENSP00000274376|ensembl:ENST00000456692|ensembl:ENSP00000411221|ensembl:ENST00000512763|ensembl:ENSP00000422008|ensembl:ENST00000515800|ensembl:ENSP00000423395|dip:DIP-144N|mint:MINT-7385857(identity) - comment:mint|no-uniprot-update: - figure legend:f4a|comment:domino|comment:mint|comment:RasGAP taxid has not been specified. taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/12/17 2014/10/16 rogid:6jx3KLadfY2YTzgZ9c75zX7X9dg-2 rogid:XmAfxJhh+X9qLWYH5F3pOlVdIGU9606 intact-crc:C9B792E2D7D5B45F|rigid:nXrO1PGaA4hYQhJhmNdxYO6Nllw false tag:?-?(MINT-7385864) binding-associated region:279-341(MINT-7385884)|tag:?-?(MINT-7385881) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant)