#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0081"(peptide array) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7738465|mint:MINT-7033161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033163(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033167(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:486A6ACAF96689C1|rigid:vwTyUwcZ+y13flrPRJa070XepMw false glutathione s tranferase tag:?-?(MINT-7033164)|binding-associated region:282-373(MINT-7033176) binding-associated region:623-633(MINT-7033181) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0081"(peptide array) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7738587|mint:MINT-7033200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033202(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033209(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:119CCAE36BEBC20F|rigid:vwTyUwcZ+y13flrPRJa070XepMw false binding-associated region:282-373(MINT-7033203)|glutathione s tranferase tag:?-?(MINT-7033206) binding-associated region:592-606(MINT-7033210) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0081"(peptide array) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7738508|mint:MINT-7033185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033187(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033194(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:132C6B4A8E421AE0|rigid:vwTyUwcZ+y13flrPRJa070XepMw false binding-associated region:282-373(MINT-7033190)|glutathione s tranferase tag:?-?(MINT-7033188) binding-associated region:647-674(MINT-7033195) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0081"(peptide array) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7738610|mint:MINT-7033215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033217(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033224(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:549C08ECC401C206|rigid:vwTyUwcZ+y13flrPRJa070XepMw false glutathione s tranferase tag:?-?(MINT-7033218)|binding-associated region:282-373(MINT-7033220) binding-associated region:796-813(MINT-7033225) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738641|mint:MINT-7033120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033122(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033123(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F3B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:09FB3F524B80C8EF|rigid:vwTyUwcZ+y13flrPRJa070XepMw false myc tag:?-?(MINT-7033130) glutathione s tranferase tag:?-?(MINT-7033142)|binding-associated region:623-640(MINT-7033144) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738662|mint:MINT-7033147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033149(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033153(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F3B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:87825A99FBEDA564|rigid:vwTyUwcZ+y13flrPRJa070XepMw false myc tag:?-?(MINT-7033150) glutathione s tranferase tag:?-?(MINT-7033156)|binding-associated region:671-743(MINT-7033154) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738703|mint:MINT-7033230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033232(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033239(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - comment:homomint|comment:mint|figure legend:F8 F5B taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:FAAD4A9AEAB4C3EA|rigid:vwTyUwcZ+y13flrPRJa070XepMw false binding-associated region:282-373(MINT-7033233)|glutathione s tranferase tag:?-?(MINT-7033236)|mutation decreasing interaction:312-312(MINT-7033247) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738733|mint:MINT-7033252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033254(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033263(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F8|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:AA9A38638EBF474F|rigid:vwTyUwcZ+y13flrPRJa070XepMw false mutation decreasing interaction:351-351(MINT-7033255)|glutathione s tranferase tag:?-?(MINT-7033257)|binding-associated region:282-373(MINT-7033259) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738768|mint:MINT-7033268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033270(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033279(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F8|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:D9EA0FF4A6986C88|rigid:vwTyUwcZ+y13flrPRJa070XepMw false mutation decreasing interaction:324-324(MINT-7033276)|binding-associated region:282-373(MINT-7033271)|glutathione s tranferase tag:?-?(MINT-7033274) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NFH8 uniprotkb:P42567 intact:EBI-7067016|ensembl:ENSP00000349824|uniprotkb:Q5JNZ8|intact:MINT-110628|uniprotkb:O43428|uniprotkb:Q8NFI5|uniprotkb:A6PWZ6 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:reps2_human(display_long)|uniprotkb:REPS2(gene name)|psi-mi:REPS2(display_short)|uniprotkb:POB1(gene name synonym)|uniprotkb:RalBP1-interacting protein 2(gene name synonym)|uniprotkb:Partner of RalBP1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738792|mint:MINT-7033284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169891(gene)|ensembl:ENST00000357277(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8NFH8|rcsb pdb:1IQ3|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_001074444.1|refseq:NP_004717.2|mint:MINT-7033286(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033295(identity) - comment:mint|function:Involved in growth factor signaling through its influence on the Ral signaling pathway - figure legend:F8|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:uOae9UghyyHGiFmm3gpLBE/Ay8Y9606 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:C132478CECC209F9|rigid:vwTyUwcZ+y13flrPRJa070XepMw false mutation disrupting interaction:312-312(MINT-7033287)|binding-associated region:282-373(MINT-7033291)|mutation disrupting interaction:351-351(MINT-7033298)|glutathione s tranferase tag:?-?(MINT-7033289) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:P42567 uniprotkb:P42567 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738835|mint:MINT-7033317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033321(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033319(identity) - - - comment:homomint|comment:mint|figure legend:F5B taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:B48D06B792130420|rigid:w2JDmkX62o5B1FFbMUHbxOmLJ6I false glutathione s tranferase tag:?-?(MINT-7033322)|binding-associated region:15-104(MINT-7033327) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P42567 uniprotkb:P42567 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738854|mint:MINT-7033333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033337(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033335(identity) - - - figure legend:F6|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:2D28BE8E31D63E31|rigid:w2JDmkX62o5B1FFbMUHbxOmLJ6I false glutathione s tranferase tag:?-?(MINT-7033338)|binding-associated region:623-640(MINT-7033343) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P42567 uniprotkb:P42567 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738821|mint:MINT-7033301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033307(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033303(identity) - - - figure legend:F5A|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:FA7334A9D28DE2B4|rigid:w2JDmkX62o5B1FFbMUHbxOmLJ6I false glutathione s tranferase tag:?-?(MINT-7033310) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P42567 uniprotkb:P42567 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0096"(pull down) Santonico et al. (2007) pubmed:18154663|mint:MINT-7033107|doi:10.1186/1471-2091-8-29 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7738892|mint:MINT-7033346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033348(identity) ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N|mint:MINT-7033354(identity) - - - figure legend:F6|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/04/15 2014/10/16 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:E1E910138E41D1A6|rigid:w2JDmkX62o5B1FFbMUHbxOmLJ6I false binding-associated region:671-743(MINT-7033349)|glutathione s tranferase tag:?-?(MINT-7033351) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)