#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P23367 uniprotkb:P28630 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name) psi-mi:"MI:0047"(far western blotting) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2505744|imex:IM-20404-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF - - crc64:87239A678FE16BE2 figure legend:Fig. 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333 intact-crc:6E20A49F6D2609BC|rigid:dvHg8AxWPbbRler+nZaOT6A/M9s false tag:c-c|tag:c-c - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P28631 uniprotkb:P23367 intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0047"(far western blotting) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2505749|imex:IM-20404-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - figure legend:Fig. 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:2D395A04285CDFBC|rigid:qcqaQoaqiaHY2i1dtGaWlk/tTgU false - tag:c-c|tag:c-c - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P06710-2 uniprotkb:P23367 intact:EBI-2604194 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0047"(far western blotting) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2505764|imex:IM-20404-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-549140(isoform-parent) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)." - figure legend:Fig. 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2015/06/09 rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:195486F76F6F8D66|rigid:9kw5X1m6zj4u4w6d8CliTp9cJMs false - tag:c-c|tag:c-c - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P03018 uniprotkb:P23367 intact:EBI-559573|uniprotkb:Q2M8B9|uniprotkb:P76758|uniprotkb:Q47709|ensemblbacteria:AAC76816|ensemblbacteria:BAE77487 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:uvrd_ecoli(display_long)|uniprotkb:uvrD(gene name)|psi-mi:uvrD(display_short)|uniprotkb:mutU(gene name synonym)|uniprotkb:pdeB(gene name synonym)|uniprotkb:rad(gene name synonym)|uniprotkb:recL(gene name synonym)|uniprotkb:b3813(locus name)|uniprotkb:JW3786(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0047"(far western blotting) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2505778|imex:IM-20404-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418258.1|refseq:WP_000383406.1|dip:DIP-11103N|ensemblbacteria:AAC76816(transcript)|ensemblbacteria:b3813(gene)|ensemblbacteria:BAE77487(gene)|ensemblbacteria:BAE77487(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0009314"(response to radiation)|go:"GO:0009432"(SOS response)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033202"(DNA helicase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070581"(rolling circle DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR005753(DNA helicase, ATP-dependent, UvrD type)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR027417|rcsb pdb:2IS1|rcsb pdb:2IS2|rcsb pdb:2IS4|rcsb pdb:2IS6|rcsb pdb:3LFU|rcsb pdb:6YI2 refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - figure legend:Fig. 2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:MjqGw9UxFqXBcoBODsYmBYkB6vc83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:7F9403D07452BFB5|rigid:3J0efT0TCDpv4hL9mCXvBaqXB/4 false - tag:c-c|tag:c-c - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P23367 uniprotkb:P03018 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-559573|uniprotkb:Q2M8B9|uniprotkb:P76758|uniprotkb:Q47709|ensemblbacteria:AAC76816|ensemblbacteria:BAE77487 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:uvrd_ecoli(display_long)|uniprotkb:uvrD(gene name)|psi-mi:uvrD(display_short)|uniprotkb:mutU(gene name synonym)|uniprotkb:pdeB(gene name synonym)|uniprotkb:rad(gene name synonym)|uniprotkb:recL(gene name synonym)|uniprotkb:b3813(locus name)|uniprotkb:JW3786(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2506148|imex:IM-20404-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_418258.1|refseq:WP_000383406.1|dip:DIP-11103N|ensemblbacteria:AAC76816(transcript)|ensemblbacteria:b3813(gene)|ensemblbacteria:BAE77487(gene)|ensemblbacteria:BAE77487(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0009314"(response to radiation)|go:"GO:0009432"(SOS response)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033202"(DNA helicase complex)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0070581"(rolling circle DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR005753(DNA helicase, ATP-dependent, UvrD type)|interpro:IPR013986(DNA helicase, DEXX box type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR027417|rcsb pdb:2IS1|rcsb pdb:2IS2|rcsb pdb:2IS4|rcsb pdb:2IS6|rcsb pdb:3LFU|rcsb pdb:6YI2 - - - figure legend:Fig. 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:MjqGw9UxFqXBcoBODsYmBYkB6vc83333 intact-crc:C9272E73B0E081A5|rigid:3J0efT0TCDpv4hL9mCXvBaqXB/4 false tag:c-c|tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06710-2 uniprotkb:P23367 intact:EBI-2604194 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2506167|imex:IM-20404-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-549140(isoform-parent) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)." - figure legend:Fig. 3.|kinetic_conditions:pH=7.5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2015/06/09 rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:86B2B4855FD3C44D|rigid:9kw5X1m6zj4u4w6d8CliTp9cJMs false - tag:c-c|tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28631 uniprotkb:P23367 intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2506177|imex:IM-20404-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - - - figure legend:Fig. 3.|kinetic_conditions:pH=7.5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:26547C260F0A7735|rigid:qcqaQoaqiaHY2i1dtGaWlk/tTgU false - tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28630 uniprotkb:P23367 intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2008) pubmed:17765269|imex:IM-20404 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2506184|imex:IM-20404-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC - crc64:87239A678FE16BE2 - figure legend:Fig. 3.|kinetic_conditions:pH=7.5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/02 2014/10/16 rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:376891CA95FF2677|rigid:dvHg8AxWPbbRler+nZaOT6A/M9s false - tag:c-c|tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)