#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43068 uniprotkb:O13684 intact:EBI-2211118|ensemblfungi:"SPBC6B1.04.1:pep" intact:EBI-2211100|uniprotkb:Q870L5|uniprotkb:Q9UTP7|ensemblfungi:"SPAC11E3.03.1:pep" psi-mi:mde4_schpo(display_long)|uniprotkb:mde4(gene name)|psi-mi:mde4(display_short)|uniprotkb:Mei4-dependent protein 4(gene name synonym)|uniprotkb:SPBC6B1.04(orf name) psi-mi:pcs1_schpo(display_long)|uniprotkb:pcs1(gene name)|psi-mi:pcs1(display_short)|uniprotkb:Chromosome segregation protein 1(gene name synonym)|uniprotkb:SPAC11E3.03(orf name) psi-mi:"MI:0676"(tandem affinity purification) Gregan et al. (2007) pubmed:17627824|imex:IM-20237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2211055|imex:IM-20237-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596083.1|dip:DIP-47342N|ensemblfungi:SPBC6B1.04(gene)|ensemblfungi:SPBC6B1.04.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR018479 refseq:NP_001018298.2|dip:DIP-47341N|ensemblfungi:SPAC11E3.03(gene)|ensemblfungi:SPAC11E3.03.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0033551"(monopolin complex)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349 - crc64:9D26F6A1BAAC5601 crc64:788A079D2920CE35 figure legend:Fig 1A, 1B|comment:Interaction occurs in mitosis and meiosis.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2009/01/22 2014/10/16 rogid:8KTUbgbNKALJSFBDalZ9gXoQ/qM284812 rogid:/fyPOLO73CVJPRM5yyIErce9Heg284812 intact-crc:07E7E522BD06F7FE|rigid:ZZfDjhUZ2H4mYBg8PVdq3FWBGj0 false - calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O13684 uniprotkb:Q9P7H1 intact:EBI-2211100|uniprotkb:Q870L5|uniprotkb:Q9UTP7|ensemblfungi:"SPAC11E3.03.1:pep" intact:EBI-704737|ensemblfungi:"SPAC1782.09c.1:pep" psi-mi:pcs1_schpo(display_long)|uniprotkb:pcs1(gene name)|psi-mi:pcs1(display_short)|uniprotkb:Chromosome segregation protein 1(gene name synonym)|uniprotkb:SPAC11E3.03(orf name) psi-mi:flp1_schpo(display_long)|uniprotkb:flp1(gene name synonym)|uniprotkb:CDC fourteen-like phosphatase 1(gene name synonym)|uniprotkb:clp1(gene name)|psi-mi:clp1(display_short)|uniprotkb:SPAC1782.09c(orf name) psi-mi:"MI:0676"(tandem affinity purification) Gregan et al. (2007) pubmed:17627824|imex:IM-20237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2211374|imex:IM-20237-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018298.2|dip:DIP-47341N|ensemblfungi:SPAC11E3.03(gene)|ensemblfungi:SPAC11E3.03.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0033551"(monopolin complex)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349 reactome:R-SPO-5687128|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|refseq:NP_594716.1|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|reactome:R-SPO-176407|interpro:IPR044506|ensemblfungi:SPAC1782.09c(gene)|ensemblfungi:SPAC1782.09c.1(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000917"(division septum assembly)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030428"(cell septum)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032153"(cell division site)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035853"(chromosome passenger complex localization to spindle midzone)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072479"(response to mitotic cell cycle spindle assembly checkpoint signaling)|go:"GO:0072686"(mitotic spindle)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120105"(mitotic actomyosin contractile ring, intermediate layer)|go:"GO:0140429"(positive regulation of mitotic sister chromatid biorientation)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990023"(mitotic spindle midzone) - crc64:788A079D2920CE35 - figure legend:Fig 1B|comment:Interaction detected in meiosis.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2009/01/22 2014/10/16 rogid:/fyPOLO73CVJPRM5yyIErce9Heg284812 rogid:Ixlk/YAwgwck5nem6QiZczRyur4284812 intact-crc:88D058C2B65ECE9A|rigid:hAaH/9B9wxQA/qUHXX3NBZgKdU0 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q10173 uniprotkb:Q9Y812 intact:EBI-1002565|ensemblfungi:"SPAC27F1.04c.1:pep" intact:EBI-1153281|ensemblfungi:"SPBC1105.17.1:pep" psi-mi:nuf2_schpo(display_long)|uniprotkb:NMS complex subunit nuf2(gene name synonym)|uniprotkb:nuf2(gene name)|psi-mi:nuf2(display_short)|uniprotkb:SPAC27F1.04c(orf name) psi-mi:cenpa_schpo(display_long)|uniprotkb:cnp1(gene name)|psi-mi:cnp1(display_short)|uniprotkb:sim2(gene name synonym)|uniprotkb:SPBC1105.17(orf name)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Silencing in the middle of the centromere protein 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Gregan et al. (2007) pubmed:17627824|imex:IM-20237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2211471|imex:IM-20237-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_594532.1|ensemblfungi:SPAC27F1.04c(gene)|ensemblfungi:SPAC27F1.04c.1(transcript)|go:"GO:0000073"(initial mitotic spindle pole body separation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0031617"(NMS complex)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0140456"(initial meiotic spindle pole body separation)|go:"GO:1990571"(meiotic centromere clustering)|interpro:IPR005549(Nuf2)|interpro:IPR038275|interpro:IPR041112|dip:DIP-36501N refseq:NP_596473.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|ensemblfungi:SPBC1105.17(gene)|ensemblfungi:SPBC1105.17.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061638"(CENP-A containing chromatin)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1990758"(mitotic sister chromatid biorientation)|reactome:R-SPO-2299718|reactome:R-SPO-2559580|reactome:R-SPO-3214841|reactome:R-SPO-3214842|reactome:R-SPO-3214847|reactome:R-SPO-3214858|reactome:R-SPO-5578749|reactome:R-SPO-5693565|reactome:R-SPO-73772|reactome:R-SPO-983231 - crc64:D716FE83223BD16E - figure legend:Fig 4K, 4L, 4M|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2009/01/22 2014/10/16 rogid:9Tdy3w3GOZ05LitTxXrMLWRq/l0284812 rogid:AaYRJN1kS2Cf0jiTUDE0EIsDFJw284812 intact-crc:ED5F1CD7A243F80E|rigid:9j/wiKGYDAg4Ln688HCC4NmvNqo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9Y738 uniprotkb:Q9Y812 intact:EBI-1002822|ensemblfungi:"SPBC409.04c.1:pep" intact:EBI-1153281|ensemblfungi:"SPBC1105.17.1:pep" psi-mi:mis12_schpo(display_long)|uniprotkb:NMS complex subunit mis12(gene name synonym)|uniprotkb:mis12(gene name)|psi-mi:mis12(display_short)|uniprotkb:SPBC409.04c(orf name) psi-mi:cenpa_schpo(display_long)|uniprotkb:cnp1(gene name)|psi-mi:cnp1(display_short)|uniprotkb:sim2(gene name synonym)|uniprotkb:SPBC1105.17(orf name)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Silencing in the middle of the centromere protein 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Gregan et al. (2007) pubmed:17627824|imex:IM-20237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2211477|imex:IM-20237-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008685(Mis12)|refseq:NP_595454.1|rcsb pdb:5WWL|ensemblfungi:SPBC409.04c(gene)|ensemblfungi:SPBC409.04c.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0031617"(NMS complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore) refseq:NP_596473.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|ensemblfungi:SPBC1105.17(gene)|ensemblfungi:SPBC1105.17.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061638"(CENP-A containing chromatin)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1990758"(mitotic sister chromatid biorientation)|reactome:R-SPO-2299718|reactome:R-SPO-2559580|reactome:R-SPO-3214841|reactome:R-SPO-3214842|reactome:R-SPO-3214847|reactome:R-SPO-3214858|reactome:R-SPO-5578749|reactome:R-SPO-5693565|reactome:R-SPO-73772|reactome:R-SPO-983231 - - - figure legend:Fig 4N, 4O|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2009/01/22 2014/10/16 rogid:yrXBkZI35gLxR1J/zwm2Q0pbJco284812 rogid:AaYRJN1kS2Cf0jiTUDE0EIsDFJw284812 intact-crc:FEAFBDFD77B7B593|rigid:cfna24ZLshw+plqibTK/f21ymhE false green fluorescent protein tag:c-c - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)