#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17214 uniprotkb:P47069 intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym) psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:"MI:0096"(pull down) Antoniacci et al. (2007) pubmed:17245108|imex:IM-19191 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2211489|imex:IM-19191-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458 sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) - crc64:9CF552AFDA6BDEDE - figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/22 2014/10/16 rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 intact-crc:140B042A23C9727E|rigid:nFvucTFiCoZXw+/a9hA2FJL2UqM false myc tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P17214 uniprotkb:P47069 intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym) psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:"MI:0096"(pull down) Antoniacci et al. (2007) pubmed:17245108|imex:IM-19191 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2211589|imex:IM-19191-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458 sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) - crc64:9CF552AFDA6BDEDE - figure legend:Fig S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/22 2014/10/16 rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 intact-crc:7CBF608CB37F555A|rigid:nFvucTFiCoZXw+/a9hA2FJL2UqM false glutathione s tranferase tag:n-n myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43605 uniprotkb:P17214 intact:EBI-22988|uniprotkb:D6VTQ7|ensemblfungi:YFR027W intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C psi-mi:eco1_yeast(display_long)|uniprotkb:ECO1(gene name)|psi-mi:ECO1(display_short)|uniprotkb:CTF7(gene name synonym)|uniprotkb:YFR027W(locus name)|uniprotkb:Establishment of cohesion protein 1(gene name synonym)|uniprotkb:Chromosome transmission fidelity protein 7(gene name synonym) psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Antoniacci et al. (2007) pubmed:17245108|imex:IM-19191 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2211598|imex:IM-19191-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116683.1|sgd:S000001923|dip:DIP-5602N|ensemblfungi:YFR027W(gene)|ensemblfungi:YFR027W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0032200"(telomere organization)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034421"(post-translational protein acetylation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0070058"(tRNA gene clustering)|go:"GO:0140588"(chromatin looping)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR028005|interpro:IPR028009|interpro:IPR033257|reactome:R-SCE-2468052 refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458 - crc64:0AF1B59BE9E71818 crc64:9CF552AFDA6BDEDE figure legend:Fig 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/22 2014/10/16 rogid:ub4jIV3f8qwGy0N1sEgvQ0/3ezQ559292 rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292 intact-crc:97C8C9BADC61F986|rigid:mNyXkiGgRNwwkKGTpboaLqVxWqU false glutathione s tranferase tag:n-n myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)