#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14683 uniprotkb:Q9UQE7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:O60216 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:Q8WVM7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:Q9NTI5 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:Q8N3U4 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:Q7Z5K2 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q14683 uniprotkb:Q29RF7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212528|imex:IM-20242-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Fig 6A|comment:Protein identities confirmed by subsequent immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 intact-crc:B80E2582B15F341A|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q8WVM7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q9NTI5 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q14683 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q9UQE7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:O60216 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q29RF7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q8N3U4 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212538|imex:IM-20242-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N - - - figure legend:Fig 6A|comment:Protein identification subsequently confirmed by immunostaining|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 intact-crc:E3AED42C23678697|rigid:MJn6Aq1I2/RAYISg4yP5CC/rzaQ false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q7Z5K2 uniprotkb:Q14683 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212554|imex:IM-20242-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:6C312F135D81B254|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:O60216 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212554|imex:IM-20242-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:6C312F135D81B254|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q9NTI5 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212554|imex:IM-20242-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 intact-crc:6C312F135D81B254|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q29RF7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212554|imex:IM-20242-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 intact-crc:6C312F135D81B254|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q8N3U4 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212554|imex:IM-20242-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 intact-crc:6C312F135D81B254|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q7Z5K2 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212562|imex:IM-20242-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:7A9EC5E839109B45|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q8N3U4 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212562|imex:IM-20242-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 intact-crc:7A9EC5E839109B45|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q9NTI5 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212562|imex:IM-20242-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 intact-crc:7A9EC5E839109B45|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:O60216 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212562|imex:IM-20242-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:7A9EC5E839109B45|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q29RF7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212562|imex:IM-20242-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 intact-crc:7A9EC5E839109B45|rigid:a1f1jx7rX0QBYnMX0QHfQAGSWQY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q29RF7 uniprotkb:O60216 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212570|imex:IM-20242-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:2D51C55384C0323C|rigid:swl+3r/U3VAyKWedhrembJwH7dM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q29RF7 uniprotkb:Q7Z5K2 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212570|imex:IM-20242-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 6C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:2D51C55384C0323C|rigid:swl+3r/U3VAyKWedhrembJwH7dM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NTI5 uniprotkb:Q7Z5K2 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212575|imex:IM-20242-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 6C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:D96E6A5D4605D733|rigid:ybyGPDN1SG3spVhzyXUT4Kk3FXg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NTI5 uniprotkb:O60216 intact:EBI-1175604|uniprotkb:Q5R3S3|uniprotkb:Q5W0K8|uniprotkb:Q6NSC3|uniprotkb:Q8IXT6|uniprotkb:Q9H5N8|uniprotkb:Q9Y2I5|uniprotkb:Q9Y451|intact:EBI-2554539|ensembl:ENSP00000313851 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:pds5b_human(display_long)|uniprotkb:Androgen-induced proliferation inhibitor(gene name synonym)|uniprotkb:Androgen-induced prostate proliferative shutoff-associated protein AS3(gene name synonym)|uniprotkb:PDS5B(gene name)|psi-mi:PDS5B(display_short)|uniprotkb:AS3(gene name synonym)|uniprotkb:KIAA0979(gene name synonym)|uniprotkb:APRIN(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212575|imex:IM-20242-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083642(gene)|ensembl:ENST00000315596(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q9NTI5|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|refseq:NP_055847.1|refseq:XP_016875939.1|dip:DIP-35420N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 6C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:MOHd5JOiq96RzbEkvMje913OAdQ9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:D96E6A5D4605D733|rigid:ybyGPDN1SG3spVhzyXUT4Kk3FXg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60216 uniprotkb:Q9UQE7 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2212586|imex:IM-20242-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:C46D6C146590FA3A|rigid:Yk3r2XPKVRNiDYyK6VVuwdD3jro false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60216 uniprotkb:Q7Z5K2 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2212586|imex:IM-20242-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2009/01/23 2014/10/16 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:C46D6C146590FA3A|rigid:Yk3r2XPKVRNiDYyK6VVuwdD3jro false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q7Z5K2 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212597|imex:IM-20242-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:997312EB11E3E76E|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q8WVM7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212597|imex:IM-20242-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 7A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:997312EB11E3E76E|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:O60216 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212597|imex:IM-20242-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:997312EB11E3E76E|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14683 uniprotkb:Q9UQE7 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212597|imex:IM-20242-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 7A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:997312EB11E3E76E|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQE7 uniprotkb:Q7Z5K2 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212603|imex:IM-20242-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:56AA45BD594B0CD3|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQE7 uniprotkb:O60216 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212603|imex:IM-20242-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:56AA45BD594B0CD3|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQE7 uniprotkb:Q8WVM7 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212603|imex:IM-20242-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:56AA45BD594B0CD3|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQE7 uniprotkb:Q14683 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212603|imex:IM-20242-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:56AA45BD594B0CD3|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q14683 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212611|imex:IM-20242-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:05A2BA737C8C5128|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q9UQE7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212611|imex:IM-20242-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:05A2BA737C8C5128|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:O60216 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212611|imex:IM-20242-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:05A2BA737C8C5128|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q8WVM7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212611|imex:IM-20242-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:05A2BA737C8C5128|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q7Z5K2 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212618|imex:IM-20242-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:31D878B17F38FFED|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q9UQE7 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212618|imex:IM-20242-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:31D878B17F38FFED|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q14683 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212618|imex:IM-20242-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:31D878B17F38FFED|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:O60216 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212618|imex:IM-20242-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7A, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:31D878B17F38FFED|rigid:ypTO/ibQFhGTcwwXNjKU4PWGfgE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60216 uniprotkb:Q7Z5K2 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212644|imex:IM-20242-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:CD569DC995DFA6FF|rigid:8JT8X6EONKBUVxjXgJl3oGYK8Bk false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:O60216 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212648|imex:IM-20242-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7B|comment:Weak interaction|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:4F5F91CF658031DD|rigid:8JT8X6EONKBUVxjXgJl3oGYK8Bk false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:Q8WVM7 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212652|imex:IM-20242-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:68507EEB0CEC7A1E|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z5K2 uniprotkb:O60216 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212652|imex:IM-20242-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:68507EEB0CEC7A1E|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false sufficient binding region:1-659 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60216 uniprotkb:Q8WVM7 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212657|imex:IM-20242-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 intact-crc:035B4D9287FE0302|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60216 uniprotkb:Q7Z5K2 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212657|imex:IM-20242-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:035B4D9287FE0302|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:Q7Z5K2 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-1022242|uniprotkb:Q5VSK5|uniprotkb:Q8IX10|uniprotkb:Q92549|uniprotkb:A7E2B5|ensembl:ENSP00000298767 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:wapl_human(display_long)|uniprotkb:WAPL(gene name)|psi-mi:WAPL(display_short)|uniprotkb:FOE(gene name synonym)|uniprotkb:Friend of EBNA2 protein(gene name synonym)|uniprotkb:KIAA0261(gene name synonym)|uniprotkb:WAPAL(gene name synonym)|uniprotkb:WAPL cohesin release factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212663|imex:IM-20242-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N refseq:NP_055860.1|refseq:NP_001305257.1|ensembl:ENSG00000062650(gene)|ensembl:ENST00000298767(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009636"(response to toxic substance)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045875"(negative regulation of sister chromatid cohesion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0072686"(mitotic spindle)|interpro:IPR012502(Wings apart-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022771|interpro:IPR039874|mint:Q7Z5K2|rcsb pdb:4K6J|go:"GO:0071922"(regulation of cohesin loading)|rcsb pdb:5HDT|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|dip:DIP-31176N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:3i6RKmQTqtFexq/ZVxKQCgNHbZw9606 intact-crc:08912D1F02C497FF|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false - sufficient binding region:1-659 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WVM7 uniprotkb:O60216 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gandhi et al. (2006) pubmed:17112726|imex:IM-20242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212663|imex:IM-20242-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - - figure legend:Fig 7B, S4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/23 2014/10/16 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:08912D1F02C497FF|rigid:o/X9q6+IbCGiUKjzmHRT5EKyna4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)