#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q08460 uniprotkb:O75791 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-740418|uniprotkb:B7Z8I3|uniprotkb:O43726|uniprotkb:Q9NRB7|ensembl:ENSP00000339186|ensembl:ENSP00000385607 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:grap2_human(display_long)|uniprotkb:Protein GADS(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:Grf40 adapter protein(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:GRBX(gene name synonym)|uniprotkb:P38(gene name synonym)|uniprotkb:Hematopoietic cell-associated adapter protein GrpL(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:SH3-SH2-SH3 adapter Mona(gene name synonym)|uniprotkb:GRAP2(gene name)|psi-mi:GRAP2(display_short)|uniprotkb:GADS(gene name synonym)|uniprotkb:GRB2L(gene name synonym)|uniprotkb:GRID(gene name synonym) psi-mi:"MI:0089"(protein array) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7058768|mint:MINT-7103057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103059(identity) refseq:NP_001278753.1|refseq:NP_001278754.1|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O75791|rcsb pdb:5GJH|reactome:R-HSA-1433557|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389356|reactome:R-HSA-9607240|interpro:IPR000980(SH2 motif)|refseq:NP_004801.1|ensembl:ENSG00000100351(gene)|ensembl:ENST00000344138(transcript)|ensembl:ENST00000407075(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007267"(cell-cell signaling)|refseq:NP_001278757.1|dip:DIP-38435N|mint:MINT-7103090(identity) - - - figure legend:f1b|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:eDZoV+vaCfLAcmbcN5LlJMDiuZ09606 intact-crc:8796E779B3E96640|rigid:gTsxjfwoIgu7hkS1TaPP1thtdRE false - binding-associated region:1-56(MINT-7103092) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99961 uniprotkb:Q08460 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0089"(protein array) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7058816|mint:MINT-7103074 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|mint:MINT-7103082(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103076(identity) - crc64:6E5BE978BC955077 - figure legend:f1b|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/22 2014/10/16 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:BDFD9F40CE82B559|rigid:2qNJKW4t1BvKuzkXwIbIJ9tSkdw false binding-associated region:306-365(MINT-7103084) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46109 uniprotkb:Q08460 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0089"(protein array) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7058800|mint:MINT-7103066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631|mint:MINT-7103099(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103068(identity) - - - figure legend:f1b|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/22 2014/10/16 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:D409C13B31A2CF83|rigid:mVznnuecgflW+oOQKtAnAwvqXUQ false binding-associated region:123-183(MINT-7103101) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08460 uniprotkb:P46109 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0096"(pull down) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7058841|mint:MINT-7103105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103110(identity) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631|mint:MINT-7103107(identity) - - - figure legend:f2b|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 intact-crc:5EC05CBF17416A6E|rigid:mVznnuecgflW+oOQKtAnAwvqXUQ false binding-associated region:?-?(MINT-7103113) binding-associated region:123-183(MINT-7103118) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14247 uniprotkb:Q08460 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0096"(pull down) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7058861|mint:MINT-7103135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7103143(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103137(identity) - - - figure legend:f2b|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/22 2014/10/16 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:C5DBB95F146F7611|rigid:uW00TVwCjw0vsr2NQ3TMeb/hZks false binding-associated region:492-550(MINT-7103147)|glutathione s tranferase tag:?-?(MINT-7103144) binding-associated region:?-?(MINT-7103138) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08460 uniprotkb:P46109 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7058944|mint:MINT-7103151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103253(identity) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631|mint:MINT-7103154(identity) - - - figure legend:f2c|comment:domino|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 intact-crc:5656B56B6456800C|rigid:mVznnuecgflW+oOQKtAnAwvqXUQ false binding-associated region:?-?(MINT-7103257)|ha tag:?-?(MINT-7103254) binding-associated region:?-?(MINT-7103157)|glutathione s tranferase tag:?-?(MINT-7103167) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08460 uniprotkb:O75791 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-740418|uniprotkb:B7Z8I3|uniprotkb:O43726|uniprotkb:Q9NRB7|ensembl:ENSP00000339186|ensembl:ENSP00000385607 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:grap2_human(display_long)|uniprotkb:Protein GADS(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:Grf40 adapter protein(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:GRBX(gene name synonym)|uniprotkb:P38(gene name synonym)|uniprotkb:Hematopoietic cell-associated adapter protein GrpL(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:SH3-SH2-SH3 adapter Mona(gene name synonym)|uniprotkb:GRAP2(gene name)|psi-mi:GRAP2(display_short)|uniprotkb:GADS(gene name synonym)|uniprotkb:GRB2L(gene name synonym)|uniprotkb:GRID(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059020|mint:MINT-7103185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103234(identity) refseq:NP_001278753.1|refseq:NP_001278754.1|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O75791|rcsb pdb:5GJH|reactome:R-HSA-1433557|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389356|reactome:R-HSA-9607240|interpro:IPR000980(SH2 motif)|refseq:NP_004801.1|ensembl:ENSG00000100351(gene)|ensembl:ENST00000344138(transcript)|ensembl:ENST00000407075(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007267"(cell-cell signaling)|refseq:NP_001278757.1|dip:DIP-38435N|mint:MINT-7103217(identity) - - - comment:domino|comment:mint|figure legend:f2e|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:eDZoV+vaCfLAcmbcN5LlJMDiuZ09606 intact-crc:951584206A037716|rigid:gTsxjfwoIgu7hkS1TaPP1thtdRE false ha tag:?-?(MINT-7103236)|binding-associated region:?-?(MINT-7103239) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08460 uniprotkb:P46109 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7058976|mint:MINT-7103170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103244(identity) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631|mint:MINT-7103211(identity) - - - figure legend:f2e|comment:domino|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 intact-crc:3B86AEFE662E3F35|rigid:mVznnuecgflW+oOQKtAnAwvqXUQ false ha tag:?-?(MINT-7103245)|binding-associated region:?-?(MINT-7103248) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14247 uniprotkb:Q08460 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059058|mint:MINT-7103197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7103199(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103225(identity) - - - comment:domino|comment:mint|figure legend:f2e f3|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:28F9E1E239F7B445|rigid:uW00TVwCjw0vsr2NQ3TMeb/hZks false - ha tag:?-?(MINT-7103226)|binding-associated region:?-?(MINT-7103229) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14247 uniprotkb:Q08460 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059107|mint:MINT-7103261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7103308(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103263(identity) - - - comment:domino|comment:mint|figure legend:f2d f3|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:3C70CF370B3D1A97|rigid:uW00TVwCjw0vsr2NQ3TMeb/hZks false - binding-associated region:?-?(MINT-7103268)|ha tag:?-?(MINT-7103265) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46109 uniprotkb:Q08460 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059220|mint:MINT-7103282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631|mint:MINT-7103305(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103284(identity) - - - figure legend:f2d|comment:domino|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:28764ED63675E8E6|rigid:mVznnuecgflW+oOQKtAnAwvqXUQ false - ha tag:?-?(MINT-7103285)|binding-associated region:?-?(MINT-7103287) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68133 uniprotkb:Q08460 intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059173|mint:MINT-7103272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1|mint:MINT-7103314(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103274(identity) - - - figure legend:f3|comment:domino|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:BA3D95C15DDC5E84|rigid:ObD79CDUAiEjnvb7tekhPV8sozk false - ha tag:?-?(MINT-7103278)|binding-associated region:?-?(MINT-7103275) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08460 uniprotkb:O75791 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 intact:EBI-740418|uniprotkb:B7Z8I3|uniprotkb:O43726|uniprotkb:Q9NRB7|ensembl:ENSP00000339186|ensembl:ENSP00000385607 psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:grap2_human(display_long)|uniprotkb:Protein GADS(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:Grf40 adapter protein(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:GRBX(gene name synonym)|uniprotkb:P38(gene name synonym)|uniprotkb:Hematopoietic cell-associated adapter protein GrpL(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:SH3-SH2-SH3 adapter Mona(gene name synonym)|uniprotkb:GRAP2(gene name)|psi-mi:GRAP2(display_short)|uniprotkb:GADS(gene name synonym)|uniprotkb:GRB2L(gene name synonym)|uniprotkb:GRID(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059256|mint:MINT-7103292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103294(identity) refseq:NP_001278753.1|refseq:NP_001278754.1|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O75791|rcsb pdb:5GJH|reactome:R-HSA-1433557|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389356|reactome:R-HSA-9607240|interpro:IPR000980(SH2 motif)|refseq:NP_004801.1|ensembl:ENSG00000100351(gene)|ensembl:ENST00000344138(transcript)|ensembl:ENST00000407075(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007267"(cell-cell signaling)|refseq:NP_001278757.1|dip:DIP-38435N|mint:MINT-7103302(identity) - - - figure legend:f2d|comment:domino|comment:mint|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/05/22 2014/10/16 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 rogid:eDZoV+vaCfLAcmbcN5LlJMDiuZ09606 intact-crc:86E564083A58A0C5|rigid:gTsxjfwoIgu7hkS1TaPP1thtdRE false binding-associated region:?-?(MINT-7103295)|ha tag:?-?(MINT-7103298) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60598 uniprotkb:Q08460 intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059312|mint:MINT-7103317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N|mint:MINT-7103320(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103319(identity) - - - figure legend:f4b|comment:mint|curation depth:mimix curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2009/05/22 2014/10/16 rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:CDD2ED08AB6D99DE|rigid:1EhGzqDotydfGF9X9MDUtFqHuxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60598 uniprotkb:Q08460 intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368 intact:EBI-1633915|uniprotkb:Q64703|uniprotkb:Q8VHF1|uniprotkb:Q9R196 psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym) psi-mi:kcma1_mouse(display_long)|uniprotkb:Kcnma1(gene name)|psi-mi:Kcnma1(display_short)|uniprotkb:Kcnma(gene name synonym)|uniprotkb:Calcium-activated potassium channel, subfamily M subunit alpha-1(gene name synonym)|uniprotkb:Maxi K channel(gene name synonym)|uniprotkb:BK channel(gene name synonym)|uniprotkb:"K(VCA)alpha"(gene name synonym)|uniprotkb:BKCA alpha(gene name synonym)|uniprotkb:KCa1.1(gene name synonym)|uniprotkb:Slowpoke homolog(gene name synonym)|uniprotkb:Slo-alpha(gene name synonym)|uniprotkb:Slo1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tian et al. (2006) pubmed:17065230|mint:MINT-7033819 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7059360|mint:MINT-7103326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N|mint:MINT-7103328(identity) refseq:NP_001240294.1|refseq:NP_001240298.1|refseq:NP_034740.2|dip:DIP-42413N|mint:Q08460|go:"GO:0001666"(response to hypoxia)|go:"GO:0003779"(actin binding)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009268"(response to pH)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030425"(dendrite)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032344"(regulation of aldosterone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046541"(saliva secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060072"(large conductance calcium-activated potassium channel activity)|go:"GO:0060073"(micturition)|go:"GO:0060082"(eye blink reflex)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1904348"(negative regulation of small intestine smooth muscle contraction)|interpro:IPR003929(Potassium channel, calcium-activated, BK, alpha subunit)|interpro:IPR005821(Ion transport)|interpro:IPR024939|interpro:IPR036291|reactome:R-MMU-1296052|mint:MINT-7103330(identity) - - - figure legend:f4b|comment:mint|curation depth:mimix curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2009/05/22 2014/10/16 rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090 rogid:lUVIPrkYhGQhPzQx4ZPSh0YUw5w10090 intact-crc:68E0036C4B235B1E|rigid:1EhGzqDotydfGF9X9MDUtFqHuxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)