#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53159 uniprotkb:P47069 intact:EBI-23834|uniprotkb:D6VU69|ensemblfungi:YGL075C intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W psi-mi:mps2_yeast(display_long)|uniprotkb:YGL075C(locus name)|uniprotkb:MPS2(gene name)|psi-mi:MPS2(display_short)|uniprotkb:MMC1(gene name synonym) psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:"MI:0401"(biochemical) Jaspersen et al. (2006) pubmed:16923827|imex:IM-18925 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212852|imex:IM-18925-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003043|refseq:NP_011440.1|dip:DIP-2989N|ensemblfungi:YGL075C(gene)|ensemblfungi:YGL075C_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005816"(spindle pole body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0071988"(protein localization to spindle pole body)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR031433 sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) - - - figure legend:Fig 4A, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:cjeUyjw2YDESx/nt9upu83VSgmA559292 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 intact-crc:784AA28846C5D1DF|rigid:TdREB3pXvB2it7Ith3H4jhLEz8o false maltose binding protein tag:n-n|sufficient binding region:328-387 mutation decreasing interaction:477-477|his tag:n-n|alexa label:?-?|sufficient binding region:457-617|mutation decreasing interaction:487-487|mutation decreasing interaction:572-572,573-573 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P06704 uniprotkb:P47069 intact:EBI-4259|uniprotkb:D6W2V8|ensemblfungi:YOR257W intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W psi-mi:cdc31_yeast(display_long)|uniprotkb:YOR257W(locus name)|uniprotkb:CDC31(gene name)|psi-mi:CDC31(display_short)|uniprotkb:DSK1(gene name synonym)|uniprotkb:Nucleoporin CDC31(gene name synonym)|uniprotkb:Nuclear pore protein CDC31(gene name synonym) psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jaspersen et al. (2006) pubmed:16923827|imex:IM-18925 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212886|imex:IM-18925-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005783|refseq:NP_014900.3|dip:DIP-2273N|mint:P06704|ensemblfungi:YOR257W(gene)|ensemblfungi:YOR257W_mRNA(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:2DOQ|rcsb pdb:2GV5|rcsb pdb:3FWB|rcsb pdb:3FWC|rcsb pdb:4MBE sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) - crc64:25A546E76E1EF520 - figure legend:Fig 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/23 2014/10/16 rogid:86I08mPe40Ad0gBR5QUCymXTekc559292 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 intact-crc:62EB58FF15FC4362|rigid:x+EwuGqFRGBJkwTIO4KW4PF46lc false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47069 uniprotkb:P53159 intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W intact:EBI-23834|uniprotkb:D6VU69|ensemblfungi:YGL075C psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:mps2_yeast(display_long)|uniprotkb:YGL075C(locus name)|uniprotkb:MPS2(gene name)|psi-mi:MPS2(display_short)|uniprotkb:MMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jaspersen et al. (2006) pubmed:16923827|imex:IM-18925 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212893|imex:IM-18925-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) sgd:S000003043|refseq:NP_011440.1|dip:DIP-2989N|ensemblfungi:YGL075C(gene)|ensemblfungi:YGL075C_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005816"(spindle pole body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0071988"(protein localization to spindle pole body)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR031433 - - - figure legend:Fig 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/23 2014/10/16 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 rogid:cjeUyjw2YDESx/nt9upu83VSgmA559292 intact-crc:C6C4915D2DC16B3A|rigid:TdREB3pXvB2it7Ith3H4jhLEz8o false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47069 uniprotkb:P53159 intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W intact:EBI-23834|uniprotkb:D6VU69|ensemblfungi:YGL075C psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:mps2_yeast(display_long)|uniprotkb:YGL075C(locus name)|uniprotkb:MPS2(gene name)|psi-mi:MPS2(display_short)|uniprotkb:MMC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jaspersen et al. (2006) pubmed:16923827|imex:IM-18925 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212905|imex:IM-18925-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) sgd:S000003043|refseq:NP_011440.1|dip:DIP-2989N|ensemblfungi:YGL075C(gene)|ensemblfungi:YGL075C_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005816"(spindle pole body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0071988"(protein localization to spindle pole body)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR031433 - - - figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 rogid:cjeUyjw2YDESx/nt9upu83VSgmA559292 intact-crc:B4C54137FDB4896C|rigid:TdREB3pXvB2it7Ith3H4jhLEz8o false his tag:n-n|sufficient binding region:457-617 binding-associated region:382-387|maltose binding protein tag:n-n|necessary binding region:329-387 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53159 uniprotkb:P47069 intact:EBI-23834|uniprotkb:D6VU69|ensemblfungi:YGL075C intact:EBI-25811|uniprotkb:D6VWG1|uniprotkb:P47070|ensemblfungi:YJL019W psi-mi:mps2_yeast(display_long)|uniprotkb:YGL075C(locus name)|uniprotkb:MPS2(gene name)|psi-mi:MPS2(display_short)|uniprotkb:MMC1(gene name synonym) psi-mi:mps3_yeast(display_long)|uniprotkb:J1310(orf name)|uniprotkb:J1315(orf name)|uniprotkb:YJL018W(orf name)|uniprotkb:YJL019W(locus name)|uniprotkb:MPS3(gene name)|psi-mi:MPS3(display_short)|uniprotkb:NEP98(gene name synonym)|uniprotkb:Monopolar spindle protein 3(gene name synonym)|uniprotkb:98 kDa nuclear envelope protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jaspersen et al. (2006) pubmed:16923827|imex:IM-18925 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2212879|imex:IM-18925-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003043|refseq:NP_011440.1|dip:DIP-2989N|ensemblfungi:YGL075C(gene)|ensemblfungi:YGL075C_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005816"(spindle pole body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0071988"(protein localization to spindle pole body)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR031433 sgd:S000003556|refseq:NP_012515.4|dip:DIP-1311N|ensemblfungi:YJL019W(gene)|ensemblfungi:YJL019W_mRNA(transcript)|go:"GO:0000741"(karyogamy)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005825"(half bridge of spindle pole body)|go:"GO:0006348"|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR012919(Sad1/UNC-like, C-terminal) - - - figure legend:Fig 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/23 2014/10/16 rogid:cjeUyjw2YDESx/nt9upu83VSgmA559292 rogid:0i+L+JfxPnQngjPzEMyUpxRpZMc559292 intact-crc:A1512E28850E9C27|rigid:TdREB3pXvB2it7Ith3H4jhLEz8o false myc tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)