#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q20655	uniprotkb:Q21921	intact:EBI-966073|ensemblmetazoa:F52D10.3a.1|ensemblmetazoa:F52D10.3a.2|ensemblmetazoa:F52D10.3a.3	intact:EBI-966082|ensemblmetazoa:R11A8.4a.1|ensemblmetazoa:R11A8.4a.2	psi-mi:14332_caeel(display_long)|uniprotkb:ftt-2(gene name)|psi-mi:ftt-2(display_short)|uniprotkb:F52D10.3(orf name)	psi-mi:sir2_caeel(display_long)|uniprotkb:sir-2.1(gene name)|psi-mi:sir-2.1(display_short)|uniprotkb:Protein sir-2.1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)|uniprotkb:R11A8.4(orf name)	psi-mi:"MI:0096"(pull down)	Wang et al. (2006)	pubmed:16860373|imex:IM-19277	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507221|imex:IM-19277-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:F52D10.3a.1(transcript)|ensemblmetazoa:F52D10.3a.2(transcript)|ensemblmetazoa:F52D10.3a.3(transcript)|ensemblmetazoa:WBGene00001502(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0040024"(dauer larval development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_509939.1|wormbase:F52D10.3a|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-9614399|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-6804114|dip:DIP-25505N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-3769402|reactome:R-CEL-9013700	ensemblmetazoa:R11A8.4a.1(transcript)|ensemblmetazoa:R11A8.4a.2(transcript)|ensemblmetazoa:WBGene00004800(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0040024"(dauer larval development)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|wormbase:R11A8.4a|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|reactome:R-CEL-3371453|reactome:R-CEL-9617629|refseq:NP_001255484.1|interpro:IPR026590|interpro:IPR029035|interpro:IPR026591|reactome:R-CEL-427359	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/11	2014/10/16	rogid:XSaQshwJqMwJE3F8Az3arYVcgXU6239	rogid:lYLThmziHA6c+E+xqjdFQSXbGrk6239	intact-crc:0AD3231D6405F063|rigid:8NKzpEN4wCEENqvlXHwgP1hvho8	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41932	uniprotkb:Q21921	intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3	intact:EBI-966082|ensemblmetazoa:R11A8.4a.1|ensemblmetazoa:R11A8.4a.2	psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym)	psi-mi:sir2_caeel(display_long)|uniprotkb:sir-2.1(gene name)|psi-mi:sir-2.1(display_short)|uniprotkb:Protein sir-2.1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)|uniprotkb:R11A8.4(orf name)	psi-mi:"MI:0096"(pull down)	Wang et al. (2006)	pubmed:16860373|imex:IM-19277	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507228|imex:IM-19277-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700	ensemblmetazoa:R11A8.4a.1(transcript)|ensemblmetazoa:R11A8.4a.2(transcript)|ensemblmetazoa:WBGene00004800(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0040024"(dauer larval development)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|wormbase:R11A8.4a|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|reactome:R-CEL-3371453|reactome:R-CEL-9617629|refseq:NP_001255484.1|interpro:IPR026590|interpro:IPR029035|interpro:IPR026591|reactome:R-CEL-427359	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/11	2014/10/16	rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239	rogid:lYLThmziHA6c+E+xqjdFQSXbGrk6239	intact-crc:A3A27AB4A1E9A7F0|rigid:fSJXkpMYuuwJZ+a2u2MW7mf6c4I	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41932	uniprotkb:Q21921	intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3	intact:EBI-966082|ensemblmetazoa:R11A8.4a.1|ensemblmetazoa:R11A8.4a.2	psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym)	psi-mi:sir2_caeel(display_long)|uniprotkb:sir-2.1(gene name)|psi-mi:sir-2.1(display_short)|uniprotkb:Protein sir-2.1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)|uniprotkb:R11A8.4(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2006)	pubmed:16860373|imex:IM-19277	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507303|imex:IM-19277-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700	ensemblmetazoa:R11A8.4a.1(transcript)|ensemblmetazoa:R11A8.4a.2(transcript)|ensemblmetazoa:WBGene00004800(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0040024"(dauer larval development)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|wormbase:R11A8.4a|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|reactome:R-CEL-3371453|reactome:R-CEL-9617629|refseq:NP_001255484.1|interpro:IPR026590|interpro:IPR029035|interpro:IPR026591|reactome:R-CEL-427359	-	-	-	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2009/12/11	2014/10/16	rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239	rogid:lYLThmziHA6c+E+xqjdFQSXbGrk6239	intact-crc:825916AF0F3807A4|rigid:fSJXkpMYuuwJZ+a2u2MW7mf6c4I	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q21921	uniprotkb:Q20655	intact:EBI-966082|ensemblmetazoa:R11A8.4a.1|ensemblmetazoa:R11A8.4a.2	intact:EBI-966073|ensemblmetazoa:F52D10.3a.1|ensemblmetazoa:F52D10.3a.2|ensemblmetazoa:F52D10.3a.3	psi-mi:sir2_caeel(display_long)|uniprotkb:sir-2.1(gene name)|psi-mi:sir-2.1(display_short)|uniprotkb:Protein sir-2.1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)|uniprotkb:R11A8.4(orf name)	psi-mi:14332_caeel(display_long)|uniprotkb:ftt-2(gene name)|psi-mi:ftt-2(display_short)|uniprotkb:F52D10.3(orf name)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2006)	pubmed:16860373|imex:IM-19277	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507334|imex:IM-19277-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:R11A8.4a.1(transcript)|ensemblmetazoa:R11A8.4a.2(transcript)|ensemblmetazoa:WBGene00004800(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0040024"(dauer larval development)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|wormbase:R11A8.4a|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|reactome:R-CEL-3371453|reactome:R-CEL-9617629|refseq:NP_001255484.1|interpro:IPR026590|interpro:IPR029035|interpro:IPR026591|reactome:R-CEL-427359	ensemblmetazoa:F52D10.3a.1(transcript)|ensemblmetazoa:F52D10.3a.2(transcript)|ensemblmetazoa:F52D10.3a.3(transcript)|ensemblmetazoa:WBGene00001502(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0040024"(dauer larval development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_509939.1|wormbase:F52D10.3a|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-9614399|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-6804114|dip:DIP-25505N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-3769402|reactome:R-CEL-9013700	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/11	2014/10/16	rogid:lYLThmziHA6c+E+xqjdFQSXbGrk6239	rogid:XSaQshwJqMwJE3F8Az3arYVcgXU6239	intact-crc:2D10AC542879D59B|rigid:8NKzpEN4wCEENqvlXHwgP1hvho8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O16850	uniprotkb:Q21921	intact:EBI-324028|uniprotkb:O16849|uniprotkb:O18676|uniprotkb:Q86S42|intact:EBI-1770827|uniprotkb:F3NWW7|uniprotkb:F3NWX0|uniprotkb:G4RQR7|uniprotkb:G4S686|uniprotkb:G4SKG3|uniprotkb:G4SKH0|ensemblmetazoa:R13H8.1h.1	intact:EBI-966082|ensemblmetazoa:R11A8.4a.1|ensemblmetazoa:R11A8.4a.2	psi-mi:foxo_caeel(display_long)|uniprotkb:Abnormal dauer formation protein 16(gene name synonym)|uniprotkb:daf-16(gene name)|psi-mi:daf-16(display_short)|uniprotkb:R13H8.1(orf name)	psi-mi:sir2_caeel(display_long)|uniprotkb:sir-2.1(gene name)|psi-mi:sir-2.1(display_short)|uniprotkb:Protein sir-2.1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)|uniprotkb:R11A8.4(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2006)	pubmed:16860373|imex:IM-19277	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507353|imex:IM-19277-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021593.1|refseq:NP_001021594.1|refseq:NP_001021595.1|refseq:NP_001021597.1|wormbase:R13H8.1a|wormbase:R13H8.1b|wormbase:R13H8.1c|wormbase:R13H8.1e|refseq:NP_001021596.1|reactome:R-CEL-9607240|refseq:NP_001021598.2|refseq:NP_001251490.1|refseq:NP_001251492.1|reactome:R-CEL-9614399|reactome:R-CEL-9615017|reactome:R-CEL-9617629|wormbase:R13H8.1d|wormbase:R13H8.1f|wormbase:R13H8.1g|wormbase:R13H8.1h|ensemblmetazoa:R13H8.1h.1(transcript)|ensemblmetazoa:WBGene00000912(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002119"(nematode larval development)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009411"(response to UV)|go:"GO:0010286"(heat acclimation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0040024"(dauer larval development)|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061065"(regulation of dauer larval development)|go:"GO:0061066"(positive regulation of dauer larval development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1905909"(regulation of dauer entry)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|go:"GO:0045087"(innate immune response)|reactome:R-CEL-198693|reactome:R-CEL-211163|reactome:R-CEL-5687128|dip:DIP-25581N|reactome:R-CEL-5689880|reactome:R-CEL-1181150|reactome:R-CEL-9617828|reactome:R-CEL-9634638	ensemblmetazoa:R11A8.4a.1(transcript)|ensemblmetazoa:R11A8.4a.2(transcript)|ensemblmetazoa:WBGene00004800(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016740"(transferase activity)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019213"(deacetylase activity)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0040024"(dauer larval development)|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070932"(histone H3 deacetylation)|wormbase:R11A8.4a|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|reactome:R-CEL-3371453|reactome:R-CEL-9617629|refseq:NP_001255484.1|interpro:IPR026590|interpro:IPR029035|interpro:IPR026591|reactome:R-CEL-427359	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2009/12/11	2014/10/16	rogid:UfAMA8NPgcJv93n6XAjW5mLboZQ6239	rogid:lYLThmziHA6c+E+xqjdFQSXbGrk6239	intact-crc:64D3DCF0DAAC7EFF|rigid:za6xVRDC4k6WWvHOqaWH0fXpS+w	false	green fluorescent protein tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)