#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-8575659 uniprotkb:O75044 intact:MINT-7059260 intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3 psi-mi:cc3(display_short)|psi-mi:EBI-8575659(display_long) psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2006) mint:MINT-7051955|doi:10.1074/jbc.M604135200|pubmed:16857672 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8575652|mint:MINT-7059250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-7059262(identity) refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1|mint:MINT-7059290(identity) - comment:mint|no-uniprot-update: - figure legend:t2|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.9x10^-6(molar) 2009/05/18 2018/01/16 rogid:UHeJTKZ6h3yXJbgFyMeZdJoQ6+U-2 rogid:/0NBTrPy/51L4LGytNP/80OifEE9606 intact-crc:F7D21A5472B8DD95|rigid:uIjJnazCzvwtEv8jQygKRVrTEJ8 false - binding-associated region:728-787(MINT-7059293) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8575659 uniprotkb:O43295 intact:MINT-7059260 intact:EBI-368166|uniprotkb:Q8IX13|uniprotkb:Q8IZV8|ensembl:ENSP00000373347 psi-mi:cc3(display_short)|psi-mi:EBI-8575659(display_long) psi-mi:srgp3_human(display_long)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2006) mint:MINT-7051955|doi:10.1074/jbc.M604135200|pubmed:16857672 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8575675|mint:MINT-7059267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-7059270(identity) refseq:NP_001028289.1|refseq:NP_055665.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O43295|reactome:R-HSA-428543|reactome:R-HSA-9013148|reactome:R-HSA-9013149|ensembl:ENSG00000196220(gene)|ensembl:ENST00000383836(transcript)|go:"GO:0005096"(GTPase activator activity)|mint:MINT-7059299(identity) - comment:mint|no-uniprot-update: - figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.6x10^-6(molar) 2009/05/18 2014/10/16 rogid:UHeJTKZ6h3yXJbgFyMeZdJoQ6+U-2 rogid:HLVloXKWOPDKajmruSjcnkctxBs9606 intact-crc:02162EB6F8A8D7EC|rigid:/kWgcLNlnGJmFO5BYKJaoYWWixc false - binding-associated region:720-779(MINT-7059301) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8575659 uniprotkb:Q7Z6B7 intact:MINT-7059260 intact:EBI-2481729|uniprotkb:Q9H8A3|uniprotkb:Q9P2P2|ensembl:ENSP00000347198 psi-mi:cc3(display_short)|psi-mi:EBI-8575659(display_long) psi-mi:srgp1_human(display_long)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Li et al. (2006) mint:MINT-7051955|doi:10.1074/jbc.M604135200|pubmed:16857672 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8575693|mint:MINT-7059278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-7059281(identity) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|interpro:IPR037451|mint:Q7Z6B7|reactome:R-HSA-428543|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_065813.1|refseq:NP_001333130.1|dip:DIP-53826N|mint:MINT-7059283(identity) - comment:mint|no-uniprot-update: - figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:4.8x10^-6(molar) 2009/05/18 2014/10/16 rogid:UHeJTKZ6h3yXJbgFyMeZdJoQ6+U-2 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 intact-crc:46E5ACADB7B2B1E1|rigid:l7rEgjWYFBxM8Z8q0X2RV/IcLwg false - binding-associated region:749-799(MINT-7059284) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)