#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P0X4 uniprotkb:Q8NEC5 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052 psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215015|imex:IM-20247-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642 - - - figure legend:Fig. 1|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/02 2014/10/16 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606 intact-crc:39B38B6DFD6CB3C1|rigid:Ar1whj6GTG6nLIEPvBadsUeedGs false - glutathione s tranferase tag:?-?|sufficient binding region:670-780 - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q96P56 uniprotkb:Q9P0X4 intact:EBI-2215024|uniprotkb:Q8NHT9|uniprotkb:Q96P54|uniprotkb:Q96P55|ensembl:ENSP00000380088 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 psi-mi:ctsr2_human(display_long)|uniprotkb:CATSPER2(gene name)|psi-mi:CATSPER2(display_short) psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215059|imex:IM-20247-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_473361.1|refseq:NP_742093.1|refseq:NP_001269238.1|ensembl:ENST00000321596|ensembl:ENSP00000321463|ensembl:ENSP00000380088|ensembl:ENST00000433380|ensembl:ENSP00000389746|refseq:XP_016877393.1|ensembl:ENSG00000166762(gene)|ensembl:ENST00000396879(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0048240"(sperm capacitation)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028747|reactome:R-HSA-1300642 refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) - - - figure legend:Fig. 1|caution:The bait proteins were a mixture of the N- and C-termini of CATSPER2. As it impossible to tell to which the prey bound, binding sites have not been annotated.|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/02 2014/10/16 rogid:Hf/+O2MyehSIhIdec5TJY532YMI9606 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 intact-crc:812A8AAB3393542A|rigid:nkRUzN9UmrSh1gERUJazE5jaokw false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:Q8NEC5 uniprotkb:Q9P0X4 intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short) psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215073|imex:IM-20247-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642 refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) - - - figure legend:Fig. 2A|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/02/02 2014/10/16 rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 intact-crc:ACB12FCBDADEC084|rigid:Ar1whj6GTG6nLIEPvBadsUeedGs false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P0X4 uniprotkb:Q96P56 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 intact:EBI-2215024|uniprotkb:Q8NHT9|uniprotkb:Q96P54|uniprotkb:Q96P55|ensembl:ENSP00000380088 psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:ctsr2_human(display_long)|uniprotkb:CATSPER2(gene name)|psi-mi:CATSPER2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215093|imex:IM-20247-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) refseq:NP_473361.1|refseq:NP_742093.1|refseq:NP_001269238.1|ensembl:ENST00000321596|ensembl:ENSP00000321463|ensembl:ENSP00000380088|ensembl:ENST00000433380|ensembl:ENSP00000389746|refseq:XP_016877393.1|ensembl:ENSG00000166762(gene)|ensembl:ENST00000396879(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0048240"(sperm capacitation)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028747|reactome:R-HSA-1300642 - - - figure legend:Fig. 2C|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/02/02 2014/10/16 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 rogid:Hf/+O2MyehSIhIdec5TJY532YMI9606 intact-crc:0A14BC0CBAAA66D7|rigid:nkRUzN9UmrSh1gERUJazE5jaokw false v5 tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P0X4 uniprotkb:Q96P56 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 intact:EBI-2215024|uniprotkb:Q8NHT9|uniprotkb:Q96P54|uniprotkb:Q96P55|ensembl:ENSP00000380088 psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:ctsr2_human(display_long)|uniprotkb:CATSPER2(gene name)|psi-mi:CATSPER2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215114|imex:IM-20247-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) refseq:NP_473361.1|refseq:NP_742093.1|refseq:NP_001269238.1|ensembl:ENST00000321596|ensembl:ENSP00000321463|ensembl:ENSP00000380088|ensembl:ENST00000433380|ensembl:ENSP00000389746|refseq:XP_016877393.1|ensembl:ENSG00000166762(gene)|ensembl:ENST00000396879(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0048240"(sperm capacitation)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028747|reactome:R-HSA-1300642 - - - figure legend:Fig. 2B|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/02/02 2014/10/16 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 rogid:Hf/+O2MyehSIhIdec5TJY532YMI9606 intact-crc:1F178F80785D7AA2|rigid:nkRUzN9UmrSh1gERUJazE5jaokw false v5 tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NEC5 uniprotkb:Q9P0X4 intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short) psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215123|imex:IM-20247-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642 refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) - - - figure legend:Fig. 2C|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/02/02 2014/10/16 rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 intact-crc:4A1CF2B849A0D4D3|rigid:Ar1whj6GTG6nLIEPvBadsUeedGs false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P0X4 uniprotkb:Q8NEC5 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052 psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215084|imex:IM-20247-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642 - - - figure legend:Fig. 2C|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/02/02 2014/10/16 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606 intact-crc:BAC0489BA3E07B63|rigid:Ar1whj6GTG6nLIEPvBadsUeedGs false v5 tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P0X4 uniprotkb:Q8NEC5 intact:EBI-1220829|uniprotkb:O95504|uniprotkb:Q5JZ88|uniprotkb:Q7Z6S9|uniprotkb:Q8NFX6|uniprotkb:Q9NZC8|uniprotkb:Q9UH15|uniprotkb:Q9UH30|uniprotkb:Q9ULU9|uniprotkb:Q9UNE6|uniprotkb:B0QY12|uniprotkb:B0QY13|uniprotkb:B0QY14|ensembl:ENSP00000385019 intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052 psi-mi:cac1i_human(display_long)|uniprotkb:CACNA1I(gene name)|psi-mi:CACNA1I(display_short)|uniprotkb:KIAA1120(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav3.3(gene name synonym) psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Zhang et al. (2006) pubmed:16740636|imex:IM-20247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-2215147|imex:IM-20247-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003406.1|refseq:NP_066919.2|ensembl:ENSG00000100346(gene)|ensembl:ENST00000402142(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030431"(sleep)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0070509"(calcium ion import)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005445(Voltage-dependent calcium channel, T-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR030162|interpro:IPR043203|reactome:R-HSA-419037|go:"GO:0008332"(low voltage-gated calcium channel activity) refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642 - - - figure legend:Fig. 7|comment:"anti-CACNA1I antibody was labelled with Alexa Fluor 488 dye as the donor (Cav3.3-488) and anti-CATSPER1 antibody with Alexa 555 dye as the acceptor"|caution:Accession number given for CACNA1l is for isoform 4 but it is not clear if this was realised at the time so interaction has been annotated to the parent UniProtKB entry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatocyte)|taxid:9606(Homo sapiens spermatocyte) - 2009/02/02 2014/10/16 rogid:qzUOlfIbLu21yINSEri/yp5TJ7o9606 rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606 intact-crc:99DA2A5D157497A7|rigid:Ar1whj6GTG6nLIEPvBadsUeedGs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)