#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14933 uniprotkb:Q6ZMZ0 intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym) psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466705|imex:IM-19399-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 - - - figure legend:fig 3|comment:IFN-beta and IL-2 treated NK 3.3 cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-nk3_3)|taxid:9606(Human NK cell line NK3.3) - 2009/10/28 2014/10/16 rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 intact-crc:2AC552F9B0FB4E9B|rigid:0gepBGgch+vk0TXVMnJwvc+zmK0 false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q6ZMZ0 uniprotkb:O14933 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156 psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466636|imex:IM-19399-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation) - - - figure legend:fig 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606 intact-crc:8136F7EB40114969|rigid:0gepBGgch+vk0TXVMnJwvc+zmK0 false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q6ZMZ0 uniprotkb:Q9NWZ5 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 intact:EBI-2466660|ensembl:ENSP00000346155|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2 psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466675|imex:IM-19399-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 ensembl:ENSG00000198276(gene)|ensembl:ENST00000354216(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|interpro:IPR029933|mint:Q9NWZ5|reactome:R-HSA-73614|refseq:NP_060329.2|refseq:NP_001180308.1 - - - figure legend:fig 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606 intact-crc:BEDDB521B91A0973|rigid:LTYyL8dclCwPmVTqumay2L7q2IY false - flag tag:n-n - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6ZMZ0 uniprotkb:P68036 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7 psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466712|imex:IM-19399-9 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N - - - figure legend:fig 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606 intact-crc:9933DE5E284188CB|rigid:rPTSvq5/zhERGdFrmupJl427MBU false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P68036 uniprotkb:Q6ZMZ0 intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym) psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466620|imex:IM-19399-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 - - - figure legend:fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 intact-crc:B103A8D83F3F5D05|rigid:rPTSvq5/zhERGdFrmupJl427MBU false flag tag:n-n myc tag:n-n|sufficient binding region:119-166(IPR001841) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O14933 uniprotkb:Q6ZMZ0 intact:EBI-2129974|uniprotkb:A6NDM6|uniprotkb:Q8N5D8|uniprotkb:A8MY53|uniprotkb:Q9UEZ0|ensembl:ENSP00000287156 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 psi-mi:ub2l6_human(display_long)|uniprotkb:UBE2L6(gene name)|psi-mi:UBE2L6(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L6(gene name synonym)|uniprotkb:Ubiquitin carrier protein L6(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:Retinoic acid-induced gene B protein(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L6(gene name synonym) psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466642|imex:IM-19399-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004214.1|refseq:NP_937826.1|ensembl:ENSP00000287156|ensembl:ENST00000340573|ensembl:ENSP00000341980|dip:DIP-41477N|ensembl:ENSG00000156587(gene)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:O14933|rcsb pdb:1WZV|rcsb pdb:1WZW|rcsb pdb:2KJH|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|ensembl:ENST00000287156(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|reactome:R-HSA-936440|reactome:R-HSA-977225|reactome:R-HSA-983168|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 - - - figure legend:2|comment:The CD2 region of RNF19B bound more strongly to UBE2l6 than did the CD1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:18K+ReSJfSpKRvnLuED+kPB3beY9606 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 intact-crc:292B16A5CFD169D4|rigid:0gepBGgch+vk0TXVMnJwvc+zmK0 false flag tag:n-n myc tag:n-n|sufficient binding region:201-251(IPR002867)|sufficient binding region:119-166(IPR001841) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NWZ5 uniprotkb:Q6ZMZ0 intact:EBI-2466660|ensembl:ENSP00000346155|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym) psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466681|imex:IM-19399-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198276(gene)|ensembl:ENST00000354216(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|interpro:IPR029933|mint:Q9NWZ5|reactome:R-HSA-73614|refseq:NP_060329.2|refseq:NP_001180308.1 go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 - - - figure legend:fig 4b|comment:Very weak binding of UCKL1 was also observed to the third cysteine-rich domain of RNF19B, binding of the CD2 was stronger than with the CD1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 intact-crc:F1CB53730BEE46CD|rigid:LTYyL8dclCwPmVTqumay2L7q2IY false flag tag:n-n sufficient binding region:201-251(IPR002867)|myc tag:n-n|sufficient binding region:119-166(IPR001841) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6ZMZ0 uniprotkb:Q9NWZ5 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 intact:EBI-2466660|ensembl:ENSP00000346155|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2 psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2466670|imex:IM-19399-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 ensembl:ENSG00000198276(gene)|ensembl:ENST00000354216(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|interpro:IPR029933|mint:Q9NWZ5|reactome:R-HSA-73614|refseq:NP_060329.2|refseq:NP_001180308.1 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/10/28 2014/10/16 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606 intact-crc:2DBD32DA916649BD|rigid:LTYyL8dclCwPmVTqumay2L7q2IY false sufficient binding region:1->318 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6ZMZ0 uniprotkb:Q9NWZ5 intact:EBI-2466594|ensembl:ENSP00000362555|uniprotkb:Q8N2S8|uniprotkb:Q6P6A4|uniprotkb:Q5TH44|uniprotkb:Q5TH45|uniprotkb:Q0VG77|uniprotkb:Q8WUF3|uniprotkb:B7ZLB2|uniprotkb:E9PAW6|uniprotkb:G3XA82 intact:EBI-2466660|ensembl:ENSP00000346155|uniprotkb:Q9H3Z2|uniprotkb:Q8N524|uniprotkb:Q70AQ5|uniprotkb:Q5JWV0|uniprotkb:B7Z8N2 psi-mi:rn19b_human(display_long)|uniprotkb:RING finger protein 19B(gene name synonym)|uniprotkb:IBR domain-containing protein 3(gene name synonym)|uniprotkb:Natural killer lytic-associated molecule(gene name synonym)|uniprotkb:RNF19B(gene name)|psi-mi:RNF19B(display_short)|uniprotkb:IBRDC3(gene name synonym)|uniprotkb:NKLAM(gene name synonym) psi-mi:uckl1_human(display_long)|uniprotkb:F538(orf name)|uniprotkb:UCKL1(gene name)|psi-mi:UCKL1(display_short)|uniprotkb:URKL1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Fortier et al. (2006) pubmed:16709802|imex:IM-19399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2466699|imex:IM-19399-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044194"(cytolytic granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|ensembl:ENST00000373456(transcript)|interpro:IPR044066|reactome:R-HSA-983168|ensembl:ENSG00000116514(gene)|refseq:NP_001120833.1|refseq:NP_699172.2|refseq:NP_001287755.1|refseq:XP_006710419.1 ensembl:ENSG00000198276(gene)|ensembl:ENST00000354216(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|interpro:IPR029933|mint:Q9NWZ5|reactome:R-HSA-73614|refseq:NP_060329.2|refseq:NP_001180308.1 go:"GO:0005737"(cytoplasm) - - figure legend:fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2009/10/28 2014/10/16 rogid:6VSvD7cN8TYTEwJISSwzuQSYFeg9606 rogid:FkKO/bZUZfOV2Fe8iGuOzC+Stpg9606 intact-crc:199B930B2E068A26|rigid:LTYyL8dclCwPmVTqumay2L7q2IY false - flag tag:n-n - - psi-mi:"MI:0708"(monoclonal antibody immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)