#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0018"(two hybrid) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2211246|imex:IM-20238-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N - - - figure legend:Fig 1a|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:D58129DBED1F032C|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false sufficient binding region:1-689 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2211462|imex:IM-20238-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N - - - figure legend:Fig 1c and 1d|comment:"The n-terminus (aa 1-474) SNAP-25 binding domain (5'LSD) of cytLEK1 is required for SNAP-25 interaction."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:C8FB79D7CEB934D6|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false necessary binding region:1-474|myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P60879 uniprotkb:Q155P7 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 intact:EBI-2211248 psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2211364|imex:IM-20238-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) - - - figure legend:Fig 1a and 1b|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/22 2014/10/16 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 intact-crc:71D12F7700918466|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false necessary binding region:1-75 necessary binding region:1-474 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60879 uniprotkb:Q155P7 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 intact:EBI-2211248 psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215400|imex:IM-20238-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 2a|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2009/01/22 2014/10/16 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 intact-crc:7F87333E3AF28D13|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215407|imex:IM-20238-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 2b and 2c|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:71A395A57DB5F00E|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215422|imex:IM-20238-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N - - - figure legend:Fig 2d|comment:SNAP-25 forms an endogenous complex containing cytLEK1/CENPF.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:B0F1517D58F4BEB2|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215447|imex:IM-20238-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 3, Fig 4a-i, Fig 6.|comment:"Coexpression of the cytLEK SNAP25 binding domain (5' LSD) and GFP-SNAP-25 demonstrated an intense overlap in a perinuclear locus. These findings demonstrate a specific interaction between 5'LSD and GFP-SNAP-25, which is not a consequence of simple protein overexpression."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:218AA69F62C6985F|rigid:W0k7ckm+w3jcsFcymWl8I2iIsQQ false necessary binding region:1-474 green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:Q9XSV7 intact:EBI-2211248 intact:EBI-2264105 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:q9xsv7_chlae(display_long)|uniprotkb:rab11(gene name)|psi-mi:rab11(display_short) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215765|imex:IM-20238-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) interpro:IPR001806(Ras GTPase)|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding) go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 4a.|comment:"The endonenous SNARE protein RAB11a colocalized in the perinuclear region in cotransfected cells coexpressed with the cytLEK SNAP-25 binding domain (5'LSD) and GFP-SNAP-25."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:rZafLx11BVZ1JYImnERBrb6pOM09534 intact-crc:86A1AF14BB611172|rigid:lPhlPQ7hKYxGoG42U7zmtOCphbs false necessary binding region:1-474 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215765|imex:IM-20238-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 4a.|comment:"The endonenous SNARE protein RAB11a colocalized in the perinuclear region in cotransfected cells coexpressed with the cytLEK SNAP-25 binding domain (5'LSD) and GFP-SNAP-25."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:86A1AF14BB611172|rigid:lPhlPQ7hKYxGoG42U7zmtOCphbs false necessary binding region:1-474 green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215778|imex:IM-20238-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 4c.|comment:"The endogenous SNARE protein syntaxin 4 colocalized in the perinuclear region in cotransfected cells coexpressed with cytLEK SNAP25 binding domain (5'LSD) and GFP-SNAP-25. Surprisingly, syntaxin 13 did not colocalize at the perinuclear region."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:F2F3E024B10F78F5 false necessary binding region:1-474 green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 intact:EBI-2264119 intact:EBI-2211248 - psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:stx4_cerae_protein(display_short)|psi-mi:EBI-2264119(display_long) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215778|imex:IM-20238-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) - go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Similar to STX4_HUMAN (Q12846). No sequence avaiilable yet." figure legend:Fig 4c.|comment:"The endogenous SNARE protein syntaxin 4 colocalized in the perinuclear region in cotransfected cells coexpressed with cytLEK SNAP25 binding domain (5'LSD) and GFP-SNAP-25. Surprisingly, syntaxin 13 did not colocalize at the perinuclear region."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 - intact-crc:F2F3E024B10F78F5 false necessary binding region:1-474 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215791|imex:IM-20238-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:Fig 4d.|comment:"The endogenous SNARE protein VAMP2 colocalized in the perinuclear region in cotransfected cells coexpressed with cytLEK SNAP25 binding domain (5'LSD) and GFP-SNAP-25. Surprisingly Vamp8 and Vamp3 did not colocalize at the perinuclear region."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:8AD16906A3FDF92A false necessary binding region:1-474 green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 intact:EBI-2264124 intact:EBI-2211248 - psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:vamp2_cerae_protein(display_short)|psi-mi:EBI-2264124(display_long) psi-mi:"MI:0663"(confocal microscopy) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2215791|imex:IM-20238-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) - go:"GO:0005737"(cytoplasm)|go:"GO:0048471"(perinuclear region of cytoplasm) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Similar to VAMP2_HUMAN (P63027). No sequence available" figure legend:Fig 4d.|comment:"The endogenous SNARE protein VAMP2 colocalized in the perinuclear region in cotransfected cells coexpressed with cytLEK SNAP25 binding domain (5'LSD) and GFP-SNAP-25. Surprisingly Vamp8 and Vamp3 did not colocalize at the perinuclear region."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 - intact-crc:8AD16906A3FDF92A false necessary binding region:1-474 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q155P7 uniprotkb:Q9XSV7 intact:EBI-2211248 intact:EBI-2264105 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:q9xsv7_chlae(display_long)|uniprotkb:rab11(gene name)|psi-mi:rab11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215563|imex:IM-20238-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) interpro:IPR001806(Ras GTPase)|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding) go:"GO:0055037"(recycling endosome) - - figure legend:Fig 5.|comment:"This demonstrates the critical proteins in the complex that links the cytLEK SNAP-25 binding domain (5'LSD) with recycling endosomes."|caution:"Although the authors have not directly proven that SNAP-25 is in the Cenf immunoprecipitate, the endogenous proteins (rab11a, myoVb and vamp2) did not coimmunoprecipitate in the absence of this protein."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:rZafLx11BVZ1JYImnERBrb6pOM09534 intact-crc:B49A67BF798B2A6B false necessary binding region:1-474|myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q155P7 uniprotkb:P60879 intact:EBI-2211248 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215563|imex:IM-20238-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N go:"GO:0055037"(recycling endosome) - - figure legend:Fig 5.|comment:"This demonstrates the critical proteins in the complex that links the cytLEK SNAP-25 binding domain (5'LSD) with recycling endosomes."|caution:"Although the authors have not directly proven that SNAP-25 is in the Cenf immunoprecipitate, the endogenous proteins (rab11a, myoVb and vamp2) did not coimmunoprecipitate in the absence of this protein."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:B49A67BF798B2A6B false necessary binding region:1-474|myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q155P7 intact:EBI-2264137 intact:EBI-2211248 - psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:myo5b_cerae_protein(display_short)|psi-mi:EBI-2264137(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215563|imex:IM-20238-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) - go:"GO:0055037"(recycling endosome) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Similar to MYO5B_HUMAN (Q9ULV0). No sequence available." figure legend:Fig 5.|comment:"This demonstrates the critical proteins in the complex that links the cytLEK SNAP-25 binding domain (5'LSD) with recycling endosomes."|caution:"Although the authors have not directly proven that SNAP-25 is in the Cenf immunoprecipitate, the endogenous proteins (rab11a, myoVb and vamp2) did not coimmunoprecipitate in the absence of this protein."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 - intact-crc:B49A67BF798B2A6B false necessary binding region:1-474|myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q155P7 intact:EBI-2264124 intact:EBI-2211248 - psi-mi:q155p7_mouse(display_long)|uniprotkb:Cenpf(gene name)|psi-mi:Cenpf(display_short)|uniprotkb:Lek1(gene name synonym) psi-mi:vamp2_cerae_protein(display_short)|psi-mi:EBI-2264124(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pooley et al. (2006) pubmed:16672379|imex:IM-20238 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215563|imex:IM-20238-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019513|interpro:IPR018463|interpro:IPR018302|interpro:IPR043513|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001822"(kidney development)|go:"GO:0002724"(regulation of T cell cytokine production)|go:"GO:0002730"(regulation of dendritic cell cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007507"(heart development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030496"(midbody)|go:"GO:0030885"(regulation of myeloid dendritic cell activation)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045120"(pronucleus)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048866"(stem cell fate specification)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0055037"(recycling endosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097539"(ciliary transition fiber) - go:"GO:0055037"(recycling endosome) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Similar to VAMP2_HUMAN (P63027). No sequence available" figure legend:Fig 5.|comment:"This demonstrates the critical proteins in the complex that links the cytLEK SNAP-25 binding domain (5'LSD) with recycling endosomes."|caution:"Although the authors have not directly proven that SNAP-25 is in the Cenf immunoprecipitate, the endogenous proteins (rab11a, myoVb and vamp2) did not coimmunoprecipitate in the absence of this protein."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/01/22 2014/10/16 rogid:b3rPf5eE6WotbUeJcEwHdYF9Gwg10090 - intact-crc:B49A67BF798B2A6B false necessary binding region:1-474|myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)