#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14247	uniprotkb:P50570	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491538|mint:MINT-7145560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145563(identity)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7145562(identity)	-	-	-	figure legend:f3e|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:36279005BA8E6518|rigid:+TOLC538u4bIHTHAomfVAwda1do	false	binding-associated region:492-550(MINT-7145571)	binding-associated region:825-839(MINT-7145566)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:Q14247	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491558|mint:MINT-7145575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145577(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145582(identity)	-	-	comment:"Stoichiometry: 2.1"	figure legend:f3e|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2022/01/19	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:1A7CB966A861E8C1|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	binding-associated region:823-837(MINT-7145578)	binding-associated region:492-550(MINT-7145583)	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14247	uniprotkb:Q9ULH1	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491591|mint:MINT-7145519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145527(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145521(identity)	-	comment:"Stoichiometry: 2.0"	-	comment:homomint|comment:mint|figure legend:f3a f3b f3c st1|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:ED891246160CFB17|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	binding-associated region:492-550(MINT-7145528)	binding-associated region:825-839(MINT-7145522)	2	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:Q14247	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491642|mint:MINT-7145630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145632(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145633(identity)	-	-	-	figure legend:f3g|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:9AA4647F9B0DBD74|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	binding-associated region:823-837(MINT-7145636)	binding-associated region:492-550(MINT-7233424)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50570	uniprotkb:Q14247	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491682|mint:MINT-7145642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7145644(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145649(identity)	-	-	-	figure legend:f3g|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:4A659309B76A49C8|rigid:+TOLC538u4bIHTHAomfVAwda1do	false	binding-associated region:825-839(MINT-7145645)	binding-associated region:492-550(MINT-7233428)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50570	uniprotkb:Q14247	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491744|mint:MINT-7145460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7145466(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145462(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f1C|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:6393A600F5C64B65|rigid:+TOLC538u4bIHTHAomfVAwda1do	false	green fluorescent protein tag:?-?(MINT-7145467)	glutathione s tranferase tag:?-?(MINT-7145463)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12931	uniprotkb:P22681	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491714|mint:MINT-7145443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N|mint:MINT-7145452(identity)	refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377|mint:MINT-7145445(identity)	-	-	-	figure legend:f1E|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	intact-crc:4F04613C3FAD2C45|rigid:kEsk22bAwI8dnnDEgsWYXhMEoic	false	glutathione s tranferase tag:?-?(MINT-7145453)|binding-associated region:84-145(MINT-7145474)	green fluorescent protein tag:?-?(MINT-7145449)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14247	uniprotkb:Q9ULH1	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491832|mint:MINT-7145594	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145597(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145596(identity)	-	-	-	figure legend:f3f|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:368F035EC910300C|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	glutathione s tranferase tag:?-?(MINT-7145603)	green fluorescent protein tag:?-?(MINT-7145599)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14247	uniprotkb:Q14247	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491832|mint:MINT-7145594	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145597(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145598(identity)	-	-	-	figure legend:f3f|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:368F035EC910300C|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	glutathione s tranferase tag:?-?(MINT-7145603)	tag:?-?(MINT-7145607)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50570	uniprotkb:Q14247	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491891|mint:MINT-7145612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7145614(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145618(identity)	-	-	-	figure legend:f3f|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:D8FB4600F5C25D96|rigid:+TOLC538u4bIHTHAomfVAwda1do	false	green fluorescent protein tag:?-?(MINT-7145615)	glutathione s tranferase tag:?-?(MINT-7145619)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:P49023	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-702209|uniprotkb:O14970|uniprotkb:O14971|uniprotkb:O60360|uniprotkb:B2RAI3|uniprotkb:Q5HYA4|uniprotkb:B7ZMB4|ensembl:ENSP00000228307	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:paxi_human(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short)	psi-mi:"MI:0096"(pull down)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8491810|mint:MINT-7145479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145481(identity)	refseq:NP_001074324.1|refseq:NP_002850.2|refseq:NP_079433.3|refseq:NP_001230685.1|refseq:XP_016875232.1|dip:DIP-33851N|ensembl:ENSG00000089159(gene)|ensembl:ENST00000228307(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0038191"(neuropilin binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060396"(growth hormone receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|mint:P49023|rcsb pdb:1KKY|rcsb pdb:1KL0|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2K2R|rcsb pdb:2O9V|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3GM1|rcsb pdb:3PY7|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3U3F|rcsb pdb:4EDN|rcsb pdb:4R32|rcsb pdb:4XGZ|rcsb pdb:4XH2|rcsb pdb:5UWH|rcsb pdb:6IUI|rcsb pdb:6PW8|rcsb pdb:6U4M|rcsb pdb:6U4N|reactome:R-HSA-180292|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-446343|reactome:R-HSA-446388|reactome:R-HSA-8849471|mint:MINT-7145488(identity)	-	-	-	figure legend:f1D|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:H8osAQRrVydLfDL97uSSA6Mf6ME9606	intact-crc:5A8958C81F790CEC|rigid:s2GMx4VOFNZJAN6H6Q+Af7i+KGI	false	glutathione s tranferase tag:?-?(MINT-7145485)|binding-associated region:1067-1129(MINT-7145482)	green fluorescent protein tag:?-?(MINT-7145489)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42680	uniprotkb:Q9ULH1	intact:EBI-1383480|uniprotkb:Q3MIS5|uniprotkb:B7ZKZ6|ensembl:ENSP00000370912	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:tec_human(display_long)|uniprotkb:PSCTK4(gene name synonym)|uniprotkb:TEC(gene name)|psi-mi:TEC(display_short)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492056|mint:MINT-7145675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003206.2|ensembl:ENSG00000135605(gene)|ensembl:ENST00000381501(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035572|interpro:IPR036028|interpro:IPR036860|mint:P42680|rcsb pdb:2LUL|reactome:R-HSA-1433557|reactome:R-HSA-2871809|reactome:R-HSA-512988|mint:MINT-7145677(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145681(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:eZR8Xggl8x1HB+0gUnzBPpbcK3Y9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:C8FAC84702D40A70|rigid:ksojR5epc3Wit63549gP8xTAFUU	false	binding-associated region:179-239(MINT-7145678)	binding-associated region:823-837(MINT-7145684)|biotin tag:?-?(MINT-7145682)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:O43586	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492005|mint:MINT-7145656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145659(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-7145658(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:96939D1CC699E2A5|rigid:EZ4//TXormdTWi5hCkgCcRS++DY	false	biotin tag:?-?(MINT-7145671)|binding-associated region:823-837(MINT-7145661)	binding-associated region:359-416(MINT-7145666)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNF0	uniprotkb:Q9ULH1	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492095|mint:MINT-7145690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828|mint:MINT-7145699(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145692(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:1324EC726D4D984F|rigid:xXlxkpd+thST/XRxjMkulSb9AhE	false	binding-associated region:426-486(MINT-7145700)	binding-associated region:823-837(MINT-7145693)|biotin tag:?-?(MINT-7145696)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15259	uniprotkb:Q9ULH1	intact:EBI-953828|uniprotkb:O14837|ensembl:ENSP00000376953	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:nphp1_human(display_long)|uniprotkb:Juvenile nephronophthisis 1 protein(gene name synonym)|uniprotkb:NPHP1(gene name)|psi-mi:NPHP1(display_short)|uniprotkb:NPH1(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492148|mint:MINT-7145706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000263.2|refseq:NP_001121650.1|refseq:NP_001121651.1|refseq:NP_997064.2|ensembl:ENSG00000144061(gene)|ensembl:ENST00000393272(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007588"(excretion)|go:"GO:0007632"(visual behavior)|go:"GO:0016020"(membrane)|go:"GO:0030030"(cell projection organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR030642|interpro:IPR036028|interpro:IPR039687|mint:O15259|rcsb pdb:1S1N|rcsb pdb:6O1Q|reactome:R-HSA-5620912|mint:MINT-7145715(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145708(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:OPdzsagqWWni+dWU+VLoygacfcg9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:1494E96621BC64E1|rigid:QegVQJmVRl7xj0X9ALn+lrSPsjI	false	binding-associated region:152-212(MINT-7145716)	biotin tag:?-?(MINT-7145709)|binding-associated region:823-837(MINT-7145711)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08631	uniprotkb:Q9ULH1	intact:EBI-346340|uniprotkb:Q29RX1|uniprotkb:Q2VPE2|uniprotkb:Q504R5|uniprotkb:Q5T7K1|uniprotkb:Q5T7K2|uniprotkb:Q96CC0|uniprotkb:Q9H5Y5|uniprotkb:Q9NUA4|uniprotkb:Q9UMJ5|uniprotkb:B4DQB6|uniprotkb:E1P5M2|uniprotkb:A8K1I1|ensembl:ENSP00000365012	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:hck_human(display_long)|uniprotkb:HCK(gene name)|psi-mi:HCK(display_short)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p59-HCK/p60-HCK(gene name synonym)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:p59Hck(gene name synonym)|uniprotkb:p61Hck(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492235|mint:MINT-7145752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165600.1|refseq:NP_001165601.1|refseq:NP_001165602.1|refseq:NP_001165604.1|refseq:NP_002101.2|dip:DIP-1051N|ensembl:ENSG00000101336(gene)|ensembl:ENST00000375852(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0002758"(innate immune response-activating signal transduction)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007498"(mesoderm development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043299"(leukocyte degranulation)|go:"GO:0045087"(innate immune response)|go:"GO:0045728"(respiratory burst after phagocytosis)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:3VS3|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035851|interpro:IPR036028|interpro:IPR036860|mint:P08631|rcsb pdb:1AD5|rcsb pdb:1BU1|rcsb pdb:1QCF|rcsb pdb:2C0I|rcsb pdb:2C0O|rcsb pdb:2C0T|rcsb pdb:2HCK|rcsb pdb:2HK5|rcsb pdb:2OI3|rcsb pdb:2OJ2|rcsb pdb:3HCK|rcsb pdb:3NHN|rcsb pdb:3RBB|rcsb pdb:3REA|rcsb pdb:3VS4|rcsb pdb:3VS5|rcsb pdb:3REB|rcsb pdb:3VS6|rcsb pdb:3VRY|rcsb pdb:3VRZ|rcsb pdb:3VS0|rcsb pdb:3VS1|rcsb pdb:3VS2|rcsb pdb:3VS7|rcsb pdb:4HCK|rcsb pdb:4LUD|rcsb pdb:4LUE|rcsb pdb:4ORZ|rcsb pdb:4U5W|rcsb pdb:5H09|rcsb pdb:5H0B|rcsb pdb:5H0G|rcsb pdb:5H0H|rcsb pdb:5HCK|rcsb pdb:5H0E|rcsb pdb:5NUH|rcsb pdb:5ZJ6|reactome:R-HSA-164944|reactome:R-HSA-2029481|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|mint:MINT-7145761(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145754(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:0ppUsdZNQdUtoKG6MdfS1bzOgZc9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:6823BF2364BA383B|rigid:j3JzHkoCUUZybgTZPf5Q3cMY98U	false	binding-associated region:78-138(MINT-7145762)	biotin tag:?-?(MINT-7145758)|binding-associated region:823-837(MINT-7145755)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:P12931	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492170|mint:MINT-7145721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145723(identity)	ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N|mint:MINT-7145730(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606	intact-crc:007CFFC284A2E7D1|rigid:yZuHFvLR4z22lLuprVlE1doOFAs	false	biotin tag:?-?(MINT-7145727)|binding-associated region:823-837(MINT-7145724)	binding-associated region:84-145(MINT-7145731)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:P06241	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492192|mint:MINT-7145736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145738(identity)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439|mint:MINT-7145745(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	intact-crc:CAE31F16D9BE6C50|rigid:PIOzuPF2VE1PxxL/0Jgsz0x+9mw	false	binding-associated region:823-837(MINT-7145741)|biotin tag:?-?(MINT-7145739)	binding-associated region:82-143(MINT-7145746)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:O75791	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-740418|uniprotkb:B7Z8I3|uniprotkb:O43726|uniprotkb:Q9NRB7|ensembl:ENSP00000339186|ensembl:ENSP00000385607	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:grap2_human(display_long)|uniprotkb:Protein GADS(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:Grf40 adapter protein(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:GRBX(gene name synonym)|uniprotkb:P38(gene name synonym)|uniprotkb:Hematopoietic cell-associated adapter protein GrpL(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:SH3-SH2-SH3 adapter Mona(gene name synonym)|uniprotkb:GRAP2(gene name)|psi-mi:GRAP2(display_short)|uniprotkb:GADS(gene name synonym)|uniprotkb:GRB2L(gene name synonym)|uniprotkb:GRID(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492274|mint:MINT-7145768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145770(identity)	refseq:NP_001278753.1|refseq:NP_001278754.1|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O75791|rcsb pdb:5GJH|reactome:R-HSA-1433557|reactome:R-HSA-202433|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389356|reactome:R-HSA-9607240|interpro:IPR000980(SH2 motif)|refseq:NP_004801.1|ensembl:ENSG00000100351(gene)|ensembl:ENST00000344138(transcript)|ensembl:ENST00000407075(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007267"(cell-cell signaling)|refseq:NP_001278757.1|dip:DIP-38435N|mint:MINT-7145777(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:eDZoV+vaCfLAcmbcN5LlJMDiuZ09606	intact-crc:1B18292F7F78A15B|rigid:XSbEmJdCdEZ5FEYp1GGrTEagKNQ	false	binding-associated region:823-837(MINT-7145773)|biotin tag:?-?(MINT-7145771)	binding-associated region:271-330(MINT-7145778)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:P16333	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492296|mint:MINT-7145783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145785(identity)	refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N|mint:MINT-7145792(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606	intact-crc:BAC490F800644A4C|rigid:t5vtBjVzUJ3ramtPt7qJ9I8mWbs	false	biotin tag:?-?(MINT-7145789)|binding-associated region:823-837(MINT-7145786)	binding-associated region:190-252(MINT-7145793)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12959	uniprotkb:Q9ULH1	intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492340|mint:MINT-7145813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1|mint:MINT-7145822(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145815(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:E2FE3B8CBC17F0D1|rigid:YApEuh+VDCaxi5+NjAHnIwmdkUY	false	binding-associated region:581-651(MINT-7145823)	binding-associated region:823-837(MINT-7145816)|biotin tag:?-?(MINT-7145819)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:Q99962	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492318|mint:MINT-7145798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145800(identity)	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N|mint:MINT-7145807(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	intact-crc:A16C594CC0189F4A|rigid:jPumIcUzfcMiVxfWAcBpJwt3f8w	false	biotin tag:?-?(MINT-7145801)|binding-associated region:823-837(MINT-7145803)	binding-associated region:290-349(MINT-7145808)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92783	uniprotkb:Q9ULH1	intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492362|mint:MINT-7145828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|mint:MINT-7145837(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145830(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:9FCC01E981326183|rigid:9KVE5N4zF49iaZ6FcxMkTe5jI6Y	false	binding-associated region:210-269(MINT-7145838)	biotin tag:?-?(MINT-7145831)|binding-associated region:823-837(MINT-7145833)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5X1	uniprotkb:Q9ULH1	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492422|mint:MINT-7145843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N|mint:MINT-7145852(identity)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145845(identity)	-	-	-	figure legend:f4|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	intact-crc:F933B5CE75ED3FFF|rigid:+KZ3UlmcrLnpMRJP6LFVW8uYPVo	false	binding-associated region:1-62(MINT-7145853)	binding-associated region:823-837(MINT-7145846)|biotin tag:?-?(MINT-7145849)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:Q14247	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492456|mint:MINT-7145426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145428(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145429(identity)	-	-	-	figure legend:f1b f1c|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:189074B09A8FEC4B|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	binding-associated region:823-837(MINT-7145434)	glutathione s tranferase tag:?-?(MINT-7145438)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50570	uniprotkb:Q14247	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492487|mint:MINT-7145500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7145503(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145502(identity)	-	-	-	figure legend:f3d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:DC379005B8C114A1|rigid:+TOLC538u4bIHTHAomfVAwda1do	false	binding-associated region:825-839(MINT-7145508)	binding-associated region:492-550(MINT-7145515)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ULH1	uniprotkb:Q14247	intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900	intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99	psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym)	psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hashimoto et al. (2006)	pubmed:16636290|mint:MINT-7102318|doi:10.1073/pnas.0509166103	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8492507|mint:MINT-7145534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X|mint:MINT-7145536(identity)	refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-7145542(identity)	-	-	-	figure legend:f3d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/06/05	2014/10/16	rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606	rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606	intact-crc:0CF4647F9BA5EC10|rigid:tCNgQPkKZe1UaMMjZGJFAI2+XsU	false	binding-associated region:823-837(MINT-7145537)	binding-associated region:492-550(MINT-7145543)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)