#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03897 uniprotkb:P05067-PRO_0000000092 intact:EBI-1246249|ensembl:ENSP00000355206 intact:EBI-821758 psi-mi:nu3m_human(display_long)|uniprotkb:MT-ND3(gene name)|psi-mi:MT-ND3(display_short)|uniprotkb:MTND3(gene name synonym)|uniprotkb:NADH3(gene name synonym)|uniprotkb:ND3(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 3(gene name synonym) psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) psi-mi:"MI:0084"(phage display) Munguia et al. (2006) pubmed:16384638|imex:IM-19302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2431705|imex:IM-19302-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024033.1|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000198840(gene)|ensembl:ENST00000361227(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009642"(response to light intensity)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|interpro:IPR000440(NADH-ubiquinone/plastoquinone oxidoreductase, chain 3)|interpro:IPR038430|rcsb pdb:5XTC|rcsb pdb:5XTD intact:EBI-77613(chain-parent) - - chain-seq-start:672|chain-seq-end:713 figure legend:Fig. 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/01 2017/03/06 rogid:gEJ3VyBx6XUv48t9ccFtS4CFZ9I9606 rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606 intact-crc:109E48870A3C31B0|rigid:iPowZJw8uPfM9g3sBLyBamxuMJM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03897 uniprotkb:P05067-PRO_0000000092 intact:EBI-1246249|ensembl:ENSP00000355206 intact:EBI-821758 psi-mi:nu3m_human(display_long)|uniprotkb:MT-ND3(gene name)|psi-mi:MT-ND3(display_short)|uniprotkb:MTND3(gene name synonym)|uniprotkb:NADH3(gene name synonym)|uniprotkb:ND3(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 3(gene name synonym) psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Munguia et al. (2006) pubmed:16384638|imex:IM-19302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2432162|imex:IM-19302-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_003024033.1|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000198840(gene)|ensembl:ENST00000361227(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009642"(response to light intensity)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|interpro:IPR000440(NADH-ubiquinone/plastoquinone oxidoreductase, chain 3)|interpro:IPR038430|rcsb pdb:5XTC|rcsb pdb:5XTD intact:EBI-77613(chain-parent) - - chain-seq-start:672|chain-seq-end:713 figure legend:2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/01 2017/03/06 rogid:gEJ3VyBx6XUv48t9ccFtS4CFZ9I9606 rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606 intact-crc:22B7D7B9F6EDC262|rigid:iPowZJw8uPfM9g3sBLyBamxuMJM false - biotin tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)