#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08719 uniprotkb:P02549 intact:EBI-7917374|intact:MINT-7211630|ensembl:ENSRNOP00000072070|uniprotkb:A0A0G2K217 intact:EBI-375617|uniprotkb:Q15514|uniprotkb:Q6LDY5|ensembl:ENSP00000495214|uniprotkb:Q5VYL1|uniprotkb:Q5VYL2 psi-mi:evl_rat(display_long)|uniprotkb:Evl(gene name)|psi-mi:Evl(display_short)|uniprotkb:Rnb6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:spta1_human(display_long)|uniprotkb:SPTA1(gene name)|psi-mi:SPTA1(display_short)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)|uniprotkb:SPTA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917399|mint:MINT-7211653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077061.1|rgd:621150|ensembl:ENSRNOG00000014476(gene)|ensembl:ENSRNOT00000080230(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:O08719|reactome:R-RNO-5663220|refseq:XP_008763073.1|refseq:XP_008763074.1|mint:MINT-7211656(identity) go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000163554(gene)|ensembl:ENST00000643759(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|interpro:IPR018159|interpro:IPR036028|mint:P02549|rcsb pdb:1OWA|rcsb pdb:3LBX|rcsb pdb:5J4O|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|interpro:IPR014837(EF-hand, Ca insensitive)|refseq:NP_003117.2|refseq:XP_011508218.1|dip:DIP-17031N|mint:MINT-7211655(identity) - comment:mint - comment:homomint|comment:mint|figure legend:f1a f1c f1d|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2017/12/01 rogid:f1EQa6HDHAS8pWwRuVDqP/+ropA10116 rogid:ypX1j52WRHo4kBjtDJWfSAF99949606 intact-crc:FF074D3C2B181069|rigid:rsuyOj0niaPGgvgnhkr2mygNUdo false - binding-associated region:980-1036(MINT-7211659) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI08 uniprotkb:Q13813 intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917448|mint:MINT-7211676 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057421.1|refseq:NP_001317150.1|ensembl:ENSG00000196405(gene)|ensembl:ENST00000402714(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220|mint:MINT-7211678(identity) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7211680(identity) - - - figure legend:f1b|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2014/10/16 rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 intact-crc:3AF5139A93C16543|rigid:vurUx6olr1AWKlqO5Y5wxxproTA false - binding-associated region:885-1229(MINT-7211681) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08719 uniprotkb:Q13813 intact:EBI-7917374|intact:MINT-7211630|ensembl:ENSRNOP00000072070|uniprotkb:A0A0G2K217 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:evl_rat(display_long)|uniprotkb:Evl(gene name)|psi-mi:Evl(display_short)|uniprotkb:Rnb6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917432|mint:MINT-7211665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077061.1|rgd:621150|ensembl:ENSRNOG00000014476(gene)|ensembl:ENSRNOT00000080230(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:O08719|reactome:R-RNO-5663220|refseq:XP_008763073.1|refseq:XP_008763074.1|mint:MINT-7211672(identity) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7211667(identity) - comment:mint - comment:homomint|comment:mint|figure legend:f1a f1c f1d|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2017/12/01 rogid:f1EQa6HDHAS8pWwRuVDqP/+ropA10116 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 intact-crc:6F9D4A6854451238|rigid:5SLM5ZC9PqCjFWQA56OmTUwk5ug false - binding-associated region:970-1026(MINT-7211668) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UI08 uniprotkb:P02549 intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720 intact:EBI-375617|uniprotkb:Q15514|uniprotkb:Q6LDY5|ensembl:ENSP00000495214|uniprotkb:Q5VYL1|uniprotkb:Q5VYL2 psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:spta1_human(display_long)|uniprotkb:SPTA1(gene name)|psi-mi:SPTA1(display_short)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)|uniprotkb:SPTA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917480|mint:MINT-7211703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057421.1|refseq:NP_001317150.1|ensembl:ENSG00000196405(gene)|ensembl:ENST00000402714(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220|mint:MINT-7211705(identity) go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000163554(gene)|ensembl:ENST00000643759(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|interpro:IPR018159|interpro:IPR036028|mint:P02549|rcsb pdb:1OWA|rcsb pdb:3LBX|rcsb pdb:5J4O|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|interpro:IPR014837(EF-hand, Ca insensitive)|refseq:NP_003117.2|refseq:XP_011508218.1|dip:DIP-17031N|mint:MINT-7211707(identity) - - - figure legend:f1c f1d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2014/10/16 rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606 rogid:ypX1j52WRHo4kBjtDJWfSAF99949606 intact-crc:06AF07270011B8AF|rigid:v55sieAOkH5YW6Jj0BSv/+SfPj0 false - binding-associated region:980-1036(MINT-7211708) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50552 uniprotkb:P02549 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 intact:EBI-375617|uniprotkb:Q15514|uniprotkb:Q6LDY5|ensembl:ENSP00000495214|uniprotkb:Q5VYL1|uniprotkb:Q5VYL2 psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:spta1_human(display_long)|uniprotkb:SPTA1(gene name)|psi-mi:SPTA1(display_short)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)|uniprotkb:SPTA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917496|mint:MINT-7211723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N|mint:MINT-7211725(identity) go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000163554(gene)|ensembl:ENST00000643759(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|interpro:IPR018159|interpro:IPR036028|mint:P02549|rcsb pdb:1OWA|rcsb pdb:3LBX|rcsb pdb:5J4O|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|interpro:IPR014837(EF-hand, Ca insensitive)|refseq:NP_003117.2|refseq:XP_011508218.1|dip:DIP-17031N|mint:MINT-7211727(identity) - - - comment:homomint|comment:mint|figure legend:f1c|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2014/10/16 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 rogid:ypX1j52WRHo4kBjtDJWfSAF99949606 intact-crc:21C01962087168D4|rigid:d7IE+23+MmKLsm6I2GKFd/LI8rk false - binding-associated region:980-1036(MINT-7211728) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13813 uniprotkb:Q9UI08 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720 psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917464|mint:MINT-7211689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7211691(identity) refseq:NP_057421.1|refseq:NP_001317150.1|ensembl:ENSG00000196405(gene)|ensembl:ENST00000402714(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220|mint:MINT-7211696(identity) - - - figure legend:f1c f1d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2014/10/16 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606 intact-crc:D5717A58FEAA1FFD|rigid:vurUx6olr1AWKlqO5Y5wxxproTA false binding-associated region:970-1026(MINT-7211692) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02549 uniprotkb:Q8N8S7 intact:EBI-375617|uniprotkb:Q15514|uniprotkb:Q6LDY5|ensembl:ENSP00000495214|uniprotkb:Q5VYL1|uniprotkb:Q5VYL2 intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809 psi-mi:spta1_human(display_long)|uniprotkb:SPTA1(gene name)|psi-mi:SPTA1(display_short)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)|uniprotkb:SPTA(gene name synonym) psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917512|mint:MINT-7211734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000163554(gene)|ensembl:ENST00000643759(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|interpro:IPR018159|interpro:IPR036028|mint:P02549|rcsb pdb:1OWA|rcsb pdb:3LBX|rcsb pdb:5J4O|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|interpro:IPR014837(EF-hand, Ca insensitive)|refseq:NP_003117.2|refseq:XP_011508218.1|dip:DIP-17031N|mint:MINT-7211736(identity) refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380(gene)|ensembl:ENST00000366844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|go:"GO:0005925"(focal adhesion)|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|reactome:R-HSA-202433|reactome:R-HSA-376176|mint:MINT-7211741(identity) - - - figure legend:f1c|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2009/06/22 2014/10/16 rogid:ypX1j52WRHo4kBjtDJWfSAF99949606 rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606 intact-crc:EEFB8E1B113DD86F|rigid:Llhe5tMu6zSxHla4KD3XZ0w2Nwk false binding-associated region:980-1036(MINT-7211737) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13813 uniprotkb:Q9UI08 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720 psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:"MI:0096"(pull down) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7917540|mint:MINT-7211745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7211747(identity) refseq:NP_057421.1|refseq:NP_001317150.1|ensembl:ENSG00000196405(gene)|ensembl:ENST00000402714(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220|mint:MINT-7211752(identity) - - - figure legend:f3|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/22 2014/10/16 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606 intact-crc:464980C9437301A4|rigid:vurUx6olr1AWKlqO5Y5wxxproTA false binding-associated region:885-1026(MINT-7211748)|glutathione s tranferase tag:?-?(MINT-7211758) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13813 uniprotkb:Q9UI08 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 intact:EBI-346653|uniprotkb:O95884|uniprotkb:Q7Z522|uniprotkb:Q8TBV1|uniprotkb:Q9UF25|uniprotkb:A8K105|uniprotkb:Q9UIC2|uniprotkb:B7Z3I5|ensembl:ENSP00000384720 psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:evl_human(display_long)|uniprotkb:EVL(gene name)|psi-mi:EVL(display_short)|uniprotkb:RNB6(gene name synonym)|uniprotkb:Ena/vasodilator-stimulated phosphoprotein-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Bournier et al. (2006) pubmed:16336193|mint:MINT-7148458|doi:10.1042/BC20050024 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7917588|mint:MINT-7211761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7211763(identity) refseq:NP_057421.1|refseq:NP_001317150.1|ensembl:ENSG00000196405(gene)|ensembl:ENST00000402714(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0045010"(actin nucleation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034319|interpro:IPR038023|mint:Q9UI08|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-5663220|mint:MINT-7211770(identity) - - - figure legend:f4a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/22 2014/10/16 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rogid:ZYA6pfvqC68sm/0egUg4hBif/Pc9606 intact-crc:D006CB424AC4A068|rigid:vurUx6olr1AWKlqO5Y5wxxproTA false - flag tag:?-?(MINT-7211777) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)