#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P0V3 uniprotkb:P42566 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912709|mint:MINT-7159813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159816(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-7159815(identity) - - - figure legend:f1c|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:A206670D75F2F9D9|rigid:jGT9uYJM94HkLZd0tEgZuvzsjcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02786 uniprotkb:Q9P0V3 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912772|mint:MINT-7159844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7159846(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159847(identity) - - - figure legend:f7a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:FB95A8FF99DC8C66|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02786 uniprotkb:Q9P0V3 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912829|mint:MINT-7159892 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7159896(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159894(identity) - - - figure legend:f7a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:D6B35B76EBAD8AF9|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05549 uniprotkb:Q9P0V3 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912802|mint:MINT-7159859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549|mint:MINT-7159863(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159861(identity) - - - figure legend:f1c|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:B0B729823ABAA302|rigid:Y08mb2Todt6Etz9k/Vr3DikIhaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50570 uniprotkb:Q9P0V3 intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912861|mint:MINT-7160329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7160333(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160331(identity) - - - figure legend:f6b|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:00E6C702E1665999|rigid:tmqsevUI5A4WcJbJzn7hOFKhX2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50570 uniprotkb:Q9P0V3 intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912849|mint:MINT-7160249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7160253(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160251(identity) - - - figure legend:f6b|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:2DC0348B93175F06|rigid:tmqsevUI5A4WcJbJzn7hOFKhX2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0V3 uniprotkb:Q9P0V3 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912926|mint:MINT-7159901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159903(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7159904(identity) - - - figure legend:f1d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:321F5A826480E233|rigid:Y9eXp3iWgXBZpAKfIJ0sE8Ytfsk false ha tag:?-?(MINT-7159906) flag tag:?-?(MINT-7159912) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50570 uniprotkb:Q9P0V3 intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7912992|mint:MINT-7160580 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|mint:MINT-7160586(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160582(identity) - - - figure legend:f7b|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:888B3706D61E8899|rigid:tmqsevUI5A4WcJbJzn7hOFKhX2Q false - binding-associated region:50-139(MINT-7160621)|ha tag:?-?(MINT-7160583)|mutation disrupting interaction:92-92(MINT-7160678) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0V3 uniprotkb:Q9P0V3 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913040|mint:MINT-7184302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7184304(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7184308(identity) - - - figure legend:f1d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:47A36836F7FFE5A4|rigid:Y9eXp3iWgXBZpAKfIJ0sE8Ytfsk false ha tag:?-?(MINT-7184305) flag tag:?-?(MINT-7184309) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0V3 uniprotkb:P02786 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913016|mint:MINT-7160658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160660(identity) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7160667(identity) - - - figure legend:f7b|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 intact-crc:241203AA8DDFAFD0|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false binding-associated region:50-139(MINT-7160661)|mutation disrupting interaction:92-92(MINT-7160674)|ha tag:?-?(MINT-7160664) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0V3 uniprotkb:P39052 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-349613|ensembl:ENSRNOP00000010948 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913108|mint:MINT-7160359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160361(identity) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7160368(identity) - - - figure legend:f6c|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 intact-crc:4C540BAFD4EC0037|rigid:gCYM3wLW81uAeFmyMzWsLllhE5A false binding-associated region:50-139(MINT-7160362)|glutathione s tranferase tag:?-?(MINT-7160365) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39052 uniprotkb:Q9P0V3 intact:EBI-349613|ensembl:ENSRNOP00000010948 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913070|mint:MINT-7160338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7160342(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160340(identity) - - - figure legend:f6c|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:AC27E268BC82A9B9|rigid:gCYM3wLW81uAeFmyMzWsLllhE5A false - glutathione s tranferase tag:?-?(MINT-7160348)|binding-associated region:50-139(MINT-7160350) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02786 uniprotkb:Q9P0V3 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913168|mint:MINT-7160681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7160690(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7160683(identity) - - - figure legend:f7c|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:8D13FA4FBDFCB98D|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false binding-associated region:1-67(MINT-7183507) binding-associated region:50-139(MINT-7160684)|glutathione s tranferase tag:?-?(MINT-7160687) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08838 uniprotkb:P39052 intact:EBI-80080 intact:EBI-349613|ensembl:ENSRNOP00000010948 psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym) psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913148|mint:MINT-7160387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-7160391(identity) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7160389(identity) - - - figure legend:f6c|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 intact-crc:D66D1B7E37DB27D0|rigid:c+zKXXlh+tBlBGBPVhNW2MRXX/M false binding-associated region:610-683(MINT-7160392)|glutathione s tranferase tag:?-?(MINT-7160395) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39052 uniprotkb:O08838 intact:EBI-349613|ensembl:ENSRNOP00000010948 intact:EBI-80080 psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913128|mint:MINT-7160372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7160381(identity) go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-7160374(identity) - - - figure legend:f6c|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116 intact-crc:D4E4DB4EC71B15A9|rigid:c+zKXXlh+tBlBGBPVhNW2MRXX/M false - binding-associated region:610-683(MINT-7160377)|glutathione s tranferase tag:?-?(MINT-7160375) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39052 uniprotkb:Q9P0V3 intact:EBI-349613|ensembl:ENSRNOP00000010948 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913215|mint:MINT-7183885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7183894(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7183887(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f7h|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:C92A866855F31F5E|rigid:gCYM3wLW81uAeFmyMzWsLllhE5A false binding-associated region:740-870(MINT-7183895)|glutathione s tranferase tag:?-?(MINT-7183924) flag tag:?-?(MINT-7183888) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39052 uniprotkb:Q9P0V3 intact:EBI-349613|ensembl:ENSRNOP00000010948 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0096"(pull down) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913191|mint:MINT-7183617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7183625(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7183620(identity) - - - figure legend:f7e|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:92446D24447AD395|rigid:gCYM3wLW81uAeFmyMzWsLllhE5A false binding-associated region:740-870(MINT-7183626) binding-associated region:50-139(MINT-7183621)|glutathione s tranferase tag:?-?(MINT-7183634) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02786 uniprotkb:Q9P0V3 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913250|mint:MINT-7183510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7183519(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7183512(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f7d|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.43x10^-5(molar) 2009/06/11 2014/10/16 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:42417AD57EF01695|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false binding-associated region:1-67(MINT-7183520) binding-associated region:50-139(MINT-7183515) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9P0V3 uniprotkb:P39052 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 intact:EBI-349613|ensembl:ENSRNOP00000010948 psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:dyn2_rat(display_long)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7913290|mint:MINT-7183533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7183536(identity) rgd:2513|refseq:NP_037331.1|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0005768"(endosome)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005813"(centrosome)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|ensembl:ENSRNOG00000007649(gene)|ensembl:ENSRNOT00000010947(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39052|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-203641|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-8856828|interpro:IPR001849(Pleckstrin-like)|refseq:XP_006242670.1|refseq:XP_006242674.1|refseq:XP_006242675.1|dip:DIP-33275N|mint:MINT-7183541(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f7d|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.03x10^-6(molar) 2009/06/11 2014/10/16 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 rogid:3wEwbCVrr/RKqmxXaZ4PJRjl+v810116 intact-crc:88476746BCDB2712|rigid:gCYM3wLW81uAeFmyMzWsLllhE5A false binding-associated region:50-139(MINT-7183537) binding-associated region:740-870(MINT-7183542) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02786 uniprotkb:Q9P0V3 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 intact:EBI-1049513|uniprotkb:O95082|uniprotkb:Q309A3|uniprotkb:Q53QD0|uniprotkb:Q53TD1|intact:EBI-28967532|ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862 psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:sh3b4_human(display_long)|uniprotkb:Transferrin receptor-trafficking protein(gene name synonym)|uniprotkb:EH-binding protein 10(gene name synonym)|uniprotkb:SH3BP4(gene name)|psi-mi:SH3BP4(display_short)|uniprotkb:BOG25(gene name synonym)|uniprotkb:EHB10(gene name synonym)|uniprotkb:TTP(gene name synonym) psi-mi:"MI:0405"(competition binding) Tosoni et al. (2005) pubmed:16325581|mint:MINT-7148471|doi:10.1016/j.cell.2005.10.021 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7913324|mint:MINT-7183598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-7183606(identity) ensembl:ENSP00000340237|ensembl:ENSP00000375867|ensembl:ENSP00000386862|refseq:XP_011509193.1|refseq:XP_011509194.1|refseq:XP_011509195.1|refseq:XP_011509196.1|refseq:NP_055336.1|ensembl:ENSG00000130147(gene)|ensembl:ENST00000344528(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034260"(negative regulation of GTPase activity)|ensembl:ENST00000392011(transcript)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000409212(transcript)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR035455|interpro:IPR035456|interpro:IPR036028|mint:Q9P0V3|reactome:R-HSA-9639288|mint:MINT-7183601(identity) - - - figure legend:f7e|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/11 2014/10/16 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rogid:tCXIWMmxXloCTB14zNmKOqTjr8g9606 intact-crc:DB4B4EB7315AE97B|rigid:fTQ07xCm9XuZjkJLfAYqSSE3JUE false binding-associated region:1-67(MINT-7183607) binding-associated region:50-139(MINT-7183602)|glutathione s tranferase tag:?-?(MINT-7183613) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)