#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28327 uniprotkb:Q16555 intact:EBI-7865560|intact:MINT-1507451|ensembl:ENSBTAP00000042484 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 psi-mi:grk1_bovin(display_long)|uniprotkb:GRK1(gene name)|psi-mi:GRK1(display_short)|uniprotkb:RHOK(gene name synonym)|uniprotkb:G protein-coupled receptor kinase 1(gene name synonym) psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0414"(enzymatic reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7865556|mint:MINT-6826109 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007601"(visual perception)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032965|interpro:IPR036305|interpro:IPR037716|mint:P28327|rcsb pdb:2I94|rcsb pdb:3C4W|rcsb pdb:3C4X|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:3C4Y|rcsb pdb:3C4Z|rcsb pdb:3C50|rcsb pdb:3C51|rcsb pdb:3QC9|rcsb pdb:3T8O|rcsb pdb:4L9I|rcsb pdb:4PNI|rcsb pdb:4WBO|go:"GO:0050254"(rhodopsin kinase activity)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|refseq:NP_776598.1|ensembl:ENSBTAG00000019963(gene)|ensembl:ENSBTAT00000045068(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|mint:MINT-6826110(identity)|uniprotkb:P28327(P28327) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826113(identity)|uniprotkb:Q16555(Q16555) - comment:mint|function:Phosphorylates rhodopsin thereby initiating its deactivation - figure legend:F1A|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:eM0swfTKn7hxl0UaF0fUxQW6DuI9913 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 intact-crc:82CFEF28FD335075|rigid:0DHHz2k7i5Coq5RanEIC121rQrY false - glutathione s tranferase tag:?-?(MINT-6826116) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16555 uniprotkb:P81948 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-6943159|ensembl:ENSBTAP00000065307|uniprotkb:Q17QT1|intact:MINT-3387904|uniprotkb:Q5E986 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:tba4a_bovin(display_long)|uniprotkb:TUBA1(gene name synonym)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865657|mint:MINT-6826124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826128(identity)|uniprotkb:Q16555(Q16555) ensembl:ENSBTAG00000030974(gene)|ensembl:ENSBTAT00000085322(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P81948|refseq:NP_001071626.1|mint:MINT-6826133(identity)|uniprotkb:P81948(P81948) - - comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain figure legend:F1A|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9913 intact-crc:984D1BA2D391E3FD|rigid:m4HHsdHO7iGkyn0IxISPnHXd5Hk false glutathione s tranferase tag:?-?(MINT-6826131) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q16555 uniprotkb:Q6B856 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-7634703|intact:MINT-6604256 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:tbb2b_bovin(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865657|mint:MINT-6826124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826128(identity)|uniprotkb:Q16555(Q16555) mint:Q6B856|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:1SA0|rcsb pdb:1SA1|rcsb pdb:1TVK|rcsb pdb:1Z2B|rcsb pdb:2P4N|rcsb pdb:2WBE|rcsb pdb:2XRP|rcsb pdb:3DCO|rcsb pdb:3DU7|rcsb pdb:3E22|rcsb pdb:3IZ0|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3J2U|rcsb pdb:4AQV|rcsb pdb:4AQW|rcsb pdb:4ATU|rcsb pdb:4ATX|rcsb pdb:4CK5|rcsb pdb:4CK6|rcsb pdb:4CK7|rcsb pdb:4I4T|rcsb pdb:4I50|rcsb pdb:4I55|rcsb pdb:4IHJ|rcsb pdb:4IIJ|rcsb pdb:4O2A|rcsb pdb:4O2B|rcsb pdb:4O4H|rcsb pdb:4O4I|rcsb pdb:4O4J|rcsb pdb:4O4L|rcsb pdb:4TUY|rcsb pdb:4TV8|rcsb pdb:4TV9|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXR|rcsb pdb:4UXS|rcsb pdb:4UXT|rcsb pdb:4UXY|rcsb pdb:4UY0|rcsb pdb:4YJ2|rcsb pdb:4YJ3|rcsb pdb:5EIB|rcsb pdb:5EZY|rcsb pdb:5GON|rcsb pdb:5H74|rcsb pdb:5H7O|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5ITZ|rcsb pdb:5IYZ|rcsb pdb:5J2T|rcsb pdb:5J2U|rcsb pdb:5JH7|rcsb pdb:5JVD|rcsb pdb:5LA6|rcsb pdb:5LOV|rcsb pdb:5LP6|rcsb pdb:5LXS|rcsb pdb:5LXT|rcsb pdb:5LYJ|rcsb pdb:5M50|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5M7G|rcsb pdb:5M8D|rcsb pdb:5M8G|rcsb pdb:5MF4|rcsb pdb:5ND2|rcsb pdb:5ND3|rcsb pdb:5ND4|rcsb pdb:5ND7|rcsb pdb:5NFZ|rcsb pdb:5NG1|rcsb pdb:5NJH|rcsb pdb:5NM5|rcsb pdb:5NQT|rcsb pdb:5NQU|rcsb pdb:5O7A|rcsb pdb:5OSK|rcsb pdb:5OV7|rcsb pdb:5S4L|rcsb pdb:5S4M|rcsb pdb:5S4N|rcsb pdb:5S4O|rcsb pdb:5S4P|rcsb pdb:5S4Q|rcsb pdb:5S4R|rcsb pdb:5S4S|rcsb pdb:5S4T|rcsb pdb:5S4U|rcsb pdb:5S4V|rcsb pdb:5M7E|rcsb pdb:5S4W|rcsb pdb:5S4X|rcsb pdb:5S4Y|rcsb pdb:5S4Z|rcsb pdb:5S50|rcsb pdb:5S51|rcsb pdb:5S52|rcsb pdb:5S53|rcsb pdb:5S54|rcsb pdb:5S55|rcsb pdb:5S56|rcsb pdb:5S57|rcsb pdb:5S58|rcsb pdb:5S59|rcsb pdb:5S5A|rcsb pdb:5S5B|rcsb pdb:5S5C|rcsb pdb:5S5D|rcsb pdb:5S5E|rcsb pdb:5S5F|rcsb pdb:5S5G|rcsb pdb:5S5H|rcsb pdb:5S5I|rcsb pdb:5S5J|rcsb pdb:5S5K|rcsb pdb:5S5L|rcsb pdb:5S5M|rcsb pdb:5S5N|rcsb pdb:5S5O|rcsb pdb:5S5P|rcsb pdb:5S5Q|rcsb pdb:5S5R|rcsb pdb:5S5S|rcsb pdb:5S5T|rcsb pdb:5S5U|rcsb pdb:5S5V|rcsb pdb:5S5W|rcsb pdb:5S5X|rcsb pdb:5S5Y|rcsb pdb:5S5Z|rcsb pdb:5S60|rcsb pdb:5S61|rcsb pdb:5S62|rcsb pdb:5S63|rcsb pdb:5S64|rcsb pdb:5S65|rcsb pdb:5S66|rcsb pdb:5S67|rcsb pdb:5XAF|rcsb pdb:5XAG|rcsb pdb:5XLT|rcsb pdb:5XLZ|rcsb pdb:5YZ3|rcsb pdb:5Z4P|rcsb pdb:5Z4U|rcsb pdb:5ZXH|rcsb pdb:6AGK|rcsb pdb:6BBN|rcsb pdb:6F7C|rcsb pdb:6EG5|rcsb pdb:6FII|rcsb pdb:6FJF|rcsb pdb:6FJM|rcsb pdb:6FKJ|rcsb pdb:6FKL|rcsb pdb:6GF3|rcsb pdb:6GJ4|rcsb pdb:6GZE|rcsb pdb:6HX8|rcsb pdb:6I5C|rcsb pdb:6JCJ|rcsb pdb:6K9V|rcsb pdb:6KNZ|rcsb pdb:6N47|rcsb pdb:6OJQ|rcsb pdb:6QQN|rcsb pdb:6QTN|rcsb pdb:6REV|rcsb pdb:6RF2|rcsb pdb:6RF8|rcsb pdb:6RFD|rcsb pdb:6S8K|rcsb pdb:6S9E|rcsb pdb:6SES|rcsb pdb:6WVL|rcsb pdb:6WVM|rcsb pdb:6WVR|rcsb pdb:6Y6D|rcsb pdb:6ZWB|rcsb pdb:6ZWC|rcsb pdb:7JFR|refseq:NP_001003900.1|dip:DIP-47524N|mint:MINT-6826125(identity)|uniprotkb:Q6B856(Q6B856) - - comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain figure legend:F1A|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:sluQMryNuOvp6xlV558+agiRwvE9913 intact-crc:984D1BA2D391E3FD|rigid:m4HHsdHO7iGkyn0IxISPnHXd5Hk false glutathione s tranferase tag:?-?(MINT-6826131) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q16555 uniprotkb:Q6B856 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-7634703|intact:MINT-6604256 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:tbb2b_bovin(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865640|mint:MINT-6826120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826151(identity)|uniprotkb:Q16555(Q16555) mint:Q6B856|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|rcsb pdb:1SA0|rcsb pdb:1SA1|rcsb pdb:1TVK|rcsb pdb:1Z2B|rcsb pdb:2P4N|rcsb pdb:2WBE|rcsb pdb:2XRP|rcsb pdb:3DCO|rcsb pdb:3DU7|rcsb pdb:3E22|rcsb pdb:3IZ0|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3J2U|rcsb pdb:4AQV|rcsb pdb:4AQW|rcsb pdb:4ATU|rcsb pdb:4ATX|rcsb pdb:4CK5|rcsb pdb:4CK6|rcsb pdb:4CK7|rcsb pdb:4I4T|rcsb pdb:4I50|rcsb pdb:4I55|rcsb pdb:4IHJ|rcsb pdb:4IIJ|rcsb pdb:4O2A|rcsb pdb:4O2B|rcsb pdb:4O4H|rcsb pdb:4O4I|rcsb pdb:4O4J|rcsb pdb:4O4L|rcsb pdb:4TUY|rcsb pdb:4TV8|rcsb pdb:4TV9|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXR|rcsb pdb:4UXS|rcsb pdb:4UXT|rcsb pdb:4UXY|rcsb pdb:4UY0|rcsb pdb:4YJ2|rcsb pdb:4YJ3|rcsb pdb:5EIB|rcsb pdb:5EZY|rcsb pdb:5GON|rcsb pdb:5H74|rcsb pdb:5H7O|rcsb pdb:5HNW|rcsb pdb:5HNX|rcsb pdb:5HNY|rcsb pdb:5HNZ|rcsb pdb:5ITZ|rcsb pdb:5IYZ|rcsb pdb:5J2T|rcsb pdb:5J2U|rcsb pdb:5JH7|rcsb pdb:5JVD|rcsb pdb:5LA6|rcsb pdb:5LOV|rcsb pdb:5LP6|rcsb pdb:5LXS|rcsb pdb:5LXT|rcsb pdb:5LYJ|rcsb pdb:5M50|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:5M5I|rcsb pdb:5M5L|rcsb pdb:5M5M|rcsb pdb:5M5N|rcsb pdb:5M5O|rcsb pdb:5M7G|rcsb pdb:5M8D|rcsb pdb:5M8G|rcsb pdb:5MF4|rcsb pdb:5ND2|rcsb pdb:5ND3|rcsb pdb:5ND4|rcsb pdb:5ND7|rcsb pdb:5NFZ|rcsb pdb:5NG1|rcsb pdb:5NJH|rcsb pdb:5NM5|rcsb pdb:5NQT|rcsb pdb:5NQU|rcsb pdb:5O7A|rcsb pdb:5OSK|rcsb pdb:5OV7|rcsb pdb:5S4L|rcsb pdb:5S4M|rcsb pdb:5S4N|rcsb pdb:5S4O|rcsb pdb:5S4P|rcsb pdb:5S4Q|rcsb pdb:5S4R|rcsb pdb:5S4S|rcsb pdb:5S4T|rcsb pdb:5S4U|rcsb pdb:5S4V|rcsb pdb:5M7E|rcsb pdb:5S4W|rcsb pdb:5S4X|rcsb pdb:5S4Y|rcsb pdb:5S4Z|rcsb pdb:5S50|rcsb pdb:5S51|rcsb pdb:5S52|rcsb pdb:5S53|rcsb pdb:5S54|rcsb pdb:5S55|rcsb pdb:5S56|rcsb pdb:5S57|rcsb pdb:5S58|rcsb pdb:5S59|rcsb pdb:5S5A|rcsb pdb:5S5B|rcsb pdb:5S5C|rcsb pdb:5S5D|rcsb pdb:5S5E|rcsb pdb:5S5F|rcsb pdb:5S5G|rcsb pdb:5S5H|rcsb pdb:5S5I|rcsb pdb:5S5J|rcsb pdb:5S5K|rcsb pdb:5S5L|rcsb pdb:5S5M|rcsb pdb:5S5N|rcsb pdb:5S5O|rcsb pdb:5S5P|rcsb pdb:5S5Q|rcsb pdb:5S5R|rcsb pdb:5S5S|rcsb pdb:5S5T|rcsb pdb:5S5U|rcsb pdb:5S5V|rcsb pdb:5S5W|rcsb pdb:5S5X|rcsb pdb:5S5Y|rcsb pdb:5S5Z|rcsb pdb:5S60|rcsb pdb:5S61|rcsb pdb:5S62|rcsb pdb:5S63|rcsb pdb:5S64|rcsb pdb:5S65|rcsb pdb:5S66|rcsb pdb:5S67|rcsb pdb:5XAF|rcsb pdb:5XAG|rcsb pdb:5XLT|rcsb pdb:5XLZ|rcsb pdb:5YZ3|rcsb pdb:5Z4P|rcsb pdb:5Z4U|rcsb pdb:5ZXH|rcsb pdb:6AGK|rcsb pdb:6BBN|rcsb pdb:6F7C|rcsb pdb:6EG5|rcsb pdb:6FII|rcsb pdb:6FJF|rcsb pdb:6FJM|rcsb pdb:6FKJ|rcsb pdb:6FKL|rcsb pdb:6GF3|rcsb pdb:6GJ4|rcsb pdb:6GZE|rcsb pdb:6HX8|rcsb pdb:6I5C|rcsb pdb:6JCJ|rcsb pdb:6K9V|rcsb pdb:6KNZ|rcsb pdb:6N47|rcsb pdb:6OJQ|rcsb pdb:6QQN|rcsb pdb:6QTN|rcsb pdb:6REV|rcsb pdb:6RF2|rcsb pdb:6RF8|rcsb pdb:6RFD|rcsb pdb:6S8K|rcsb pdb:6S9E|rcsb pdb:6SES|rcsb pdb:6WVL|rcsb pdb:6WVM|rcsb pdb:6WVR|rcsb pdb:6Y6D|rcsb pdb:6ZWB|rcsb pdb:6ZWC|rcsb pdb:7JFR|refseq:NP_001003900.1|dip:DIP-47524N|mint:MINT-6826121(identity)|uniprotkb:Q6B856(Q6B856) - - comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain figure legend:F1C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:sluQMryNuOvp6xlV558+agiRwvE9913 intact-crc:5E83C2DBEB09C3DE|rigid:m4HHsdHO7iGkyn0IxISPnHXd5Hk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16555 uniprotkb:P81948 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-6943159|ensembl:ENSBTAP00000065307|uniprotkb:Q17QT1|intact:MINT-3387904|uniprotkb:Q5E986 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:tba4a_bovin(display_long)|uniprotkb:TUBA1(gene name synonym)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865640|mint:MINT-6826120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826151(identity)|uniprotkb:Q16555(Q16555) ensembl:ENSBTAG00000030974(gene)|ensembl:ENSBTAT00000085322(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P81948|refseq:NP_001071626.1|mint:MINT-6826154(identity)|uniprotkb:P81948(P81948) - - comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain figure legend:F1C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9913 intact-crc:5E83C2DBEB09C3DE|rigid:m4HHsdHO7iGkyn0IxISPnHXd5Hk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16555 uniprotkb:Q2LC84 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-7865699|uniprotkb:B2GVA9|intact:MINT-6825111|uniprotkb:F1MAI8 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:numb_rat(display_long)|uniprotkb:Numb(gene name)|psi-mi:Numb(display_short) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865694|mint:MINT-6826136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826143(identity)|uniprotkb:Q16555(Q16555) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|reactome:R-RNO-437239|reactome:R-RNO-5610780|reactome:R-RNO-5632684|mint:Q2LC84|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|interpro:IPR006020(Phosphotyrosine interaction region)|rgd:620107|mint:MINT-6826140(identity)|uniprotkb:B2GVA9(B2GVA9) - - comment:mint figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:glGvjtSgEtUZYE81TErzlKmTaVA10116 intact-crc:F158B3C721905E3B|rigid:6WMzym0q2nYXtrQhtCfEmKuGEXs false glutathione s tranferase tag:?-?(MINT-6826146) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q16555 uniprotkb:P60711 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865694|mint:MINT-6826136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826143(identity)|uniprotkb:Q16555(Q16555) rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711|mint:MINT-6826137(identity)|uniprotkb:P60711(P60711) - - - figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116 intact-crc:F158B3C721905E3B|rigid:6WMzym0q2nYXtrQhtCfEmKuGEXs false glutathione s tranferase tag:?-?(MINT-6826146) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q16555 uniprotkb:P68370 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232 psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym) psi-mi:"MI:0096"(pull down) Arimura et al. (2005) pubmed:16260611|mint:MINT-6826103|doi:10.1128/MCB.25.22.9973-9984.20 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7865694|mint:MINT-6826136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1|mint:MINT-6826143(identity)|uniprotkb:Q16555(Q16555) rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189|mint:MINT-6826148(identity)|uniprotkb:P68370(P68370) - - - figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/23 2014/10/16 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116 intact-crc:F158B3C721905E3B|rigid:6WMzym0q2nYXtrQhtCfEmKuGEXs false glutathione s tranferase tag:?-?(MINT-6826146) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)