#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P29474 uniprotkb:Q8IVI9 intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 psi-mi:nos3_human(display_long)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short) psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:"MI:0096"(pull down) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848755|mint:MINT-7213409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|ensembl:ENSG00000164867(gene)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042311"(vasodilation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0097746"(blood vessel diameter maintenance)|ensembl:ENST00000297494(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007263"(nitric oxide mediated signal transduction)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391|mint:MINT-7213414(identity) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213411(identity) - - - comment:homomint|comment:mint|figure legend:4a|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/30 2018/04/06 rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 intact-crc:23E17FC3CBD81EED|rigid:+rZKVR9ltxTy5J+4XnHED+KP9uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:O08816 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-6142604 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0096"(pull down) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848777|mint:MINT-7213422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213424(identity) mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane)|mint:MINT-7213425(identity) - - - comment:homomint|comment:mint|figure legend:4a|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 intact-crc:76709E67AB3CD253|rigid:1xqvCflVM3aSEzJkYUSHyezrQ8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:Q05193 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym) psi-mi:"MI:0096"(pull down) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848766|mint:MINT-7213417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213421(identity) refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|mint:MINT-7213419(identity) - - - comment:homomint|comment:mint|figure legend:4a|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606 intact-crc:1BA11FB4387008E6|rigid:ojCqwtmQiE6I+yZG18b0UhlFg2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:O08816 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-6142604 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0096"(pull down) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848807|mint:MINT-7213444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213448(identity) mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane)|mint:MINT-7213446(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:4c|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 intact-crc:8F1E4F95FCE46FB7|rigid:1xqvCflVM3aSEzJkYUSHyezrQ8g false binding-associated region:?-?(MINT-7213454) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:Q05193 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym) psi-mi:"MI:0096"(pull down) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848788|mint:MINT-7213439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213443(identity) refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|mint:MINT-7213441(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:4c|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606 intact-crc:23918BBAD77B4909|rigid:ojCqwtmQiE6I+yZG18b0UhlFg2A false binding-associated region:?-?(MINT-7213450) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29474 uniprotkb:Q8IVI9 intact:EBI-1391623|uniprotkb:A0S0A7|uniprotkb:E9PFR2|uniprotkb:Q13662|uniprotkb:Q14251|uniprotkb:Q14434|uniprotkb:Q6GSL5|uniprotkb:A8KA63|uniprotkb:B2RCQ1|uniprotkb:Q548C1|uniprotkb:Q9UDC6|uniprotkb:A0S0A8|ensembl:ENSP00000297494 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 psi-mi:nos3_human(display_long)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NOS3(gene name)|psi-mi:NOS3(display_short) psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848836|mint:MINT-7213465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000594.2|refseq:NP_001153581.1|refseq:NP_001153582.1|refseq:NP_001153583.1|refseq:XP_016867721.1|dip:DIP-38479N|ensembl:ENSG00000164867(gene)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042311"(vasodilation)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0097746"(blood vessel diameter maintenance)|ensembl:ENST00000297494(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007263"(nitric oxide mediated signal transduction)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|mint:P29474|rcsb pdb:1M9J|rcsb pdb:1M9K|rcsb pdb:1M9M|rcsb pdb:1M9Q|rcsb pdb:1M9R|rcsb pdb:1NIW|rcsb pdb:2LL7|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2MG5|rcsb pdb:2N8J|rcsb pdb:3EAH|rcsb pdb:3NOS|rcsb pdb:4D1O|rcsb pdb:4D1P|rcsb pdb:5UO8|rcsb pdb:5UO9|rcsb pdb:5UOA|rcsb pdb:5UOB|rcsb pdb:5UOC|rcsb pdb:5VVB|rcsb pdb:5VVC|rcsb pdb:5VVD|rcsb pdb:5XOF|rcsb pdb:6AV6|rcsb pdb:6AV7|rcsb pdb:6CIE|rcsb pdb:6CIF|rcsb pdb:6NH1|rcsb pdb:6NH2|rcsb pdb:6NH3|rcsb pdb:6NH4|rcsb pdb:6NH5|rcsb pdb:6NH6|rcsb pdb:6NH7|rcsb pdb:6NH8|rcsb pdb:6NHF|rcsb pdb:6POU|rcsb pdb:6POV|rcsb pdb:6POW|rcsb pdb:6POX|rcsb pdb:6POY|rcsb pdb:6POZ|rcsb pdb:6PP0|rcsb pdb:6PP1|rcsb pdb:6PP2|rcsb pdb:6PP3|rcsb pdb:6PP4|reactome:R-HSA-1222556|reactome:R-HSA-1474151|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-203754|reactome:R-HSA-392154|reactome:R-HSA-5218920|reactome:R-HSA-9009391|mint:MINT-7213467(identity) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213469(identity) - - - comment:homomint|comment:mint|figure legend:4b|curation depth:mimix curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2009/06/30 2018/04/06 rogid:FIvVY2y5ltfs8KVWaMEHCEt2pMk9606 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 intact-crc:115EF307A5BE7549|rigid:+rZKVR9ltxTy5J+4XnHED+KP9uU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:O08816 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-6142604 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848858|mint:MINT-7213475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213479(identity) mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane)|mint:MINT-7213477(identity) - - - comment:homomint|comment:mint|figure legend:4b|curation depth:mimix curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 intact-crc:1EB1F83050CEDFC9|rigid:1xqvCflVM3aSEzJkYUSHyezrQ8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IVI9 uniprotkb:Q05193 intact:EBI-1391643|uniprotkb:Q27HG3|uniprotkb:Q53S62|uniprotkb:Q96CJ9|uniprotkb:A8K2I9|uniprotkb:B3KSF5|uniprotkb:E7EPT9|ensembl:ENSP00000318921 intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014 psi-mi:nostn_human(display_long)|uniprotkb:eNOS-trafficking inducer(gene name synonym)|uniprotkb:Nitric oxide synthase trafficker(gene name synonym)|uniprotkb:Nitric oxide synthase traffic inducer(gene name synonym)|uniprotkb:BM247 homolog(gene name synonym)|uniprotkb:NOSTRIN(gene name)|psi-mi:NOSTRIN(display_short) psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Icking et al. (2005) pubmed:16234328|mint:MINT-7213401|doi:10.1242/jcs.02620 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7848847|mint:MINT-7213470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034813.2|refseq:NP_001165102.1|refseq:NP_001165103.1|refseq:NP_443178.2|ensembl:ENSG00000163072(gene)|ensembl:ENST00000317647(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267|interpro:IPR028535|interpro:IPR031160|interpro:IPR035656|interpro:IPR036028|interpro:IPR036274|mint:Q8IVI9|rcsb pdb:2YUN|reactome:R-HSA-203641|mint:MINT-7213474(identity) refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|mint:MINT-7213472(identity) - - - comment:homomint|comment:mint|figure legend:4b|curation depth:mimix curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2009/06/30 2014/10/16 rogid:995orjHO0YRgvNcLMP1kX2qC25s9606 rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606 intact-crc:7950EA2D814F0C5A|rigid:ojCqwtmQiE6I+yZG18b0UhlFg2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)