#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53632	uniprotkb:P40985	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	intact:EBI-2045008|uniprotkb:D6VWK9|ensemblfungi:YJR036C	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:hul4_yeast(display_long)|uniprotkb:HECT ubiquitin ligase 4(gene name synonym)|uniprotkb:HUL4(gene name)|psi-mi:HUL4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HUL4(gene name synonym)|uniprotkb:J1608(orf name)|uniprotkb:YJR036C(locus name)	psi-mi:"MI:0096"(pull down)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209909|imex:IM-20232-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	sgd:S000003797|interpro:IPR000569(HECT)|refseq:NP_012570.3|mint:P40985|interpro:IPR035983|ensemblfungi:YJR036C(gene)|ensemblfungi:YJR036C_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031499"(TRAMP complex)	-	crc64:8A58B29E4BFDC022	-	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	rogid:OW6nyv6vF/FLoAJSb+PWol4oP0Q559292	intact-crc:173ED1A3CEE40AA5|rigid:XTgYp4gRUkvEewGnYnWKS5Jv9sU	false	protein a tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53632	uniprotkb:P47047	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209909|imex:IM-20232-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	-	crc64:8A58B29E4BFDC022	crc64:1FA9EAADC546F669	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	intact-crc:173ED1A3CEE40AA5|rigid:XTgYp4gRUkvEewGnYnWKS5Jv9sU	false	protein a tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53632	uniprotkb:Q12476	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:"MI:0096"(pull down)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209909|imex:IM-20232-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	-	crc64:8A58B29E4BFDC022	crc64:5915C97FA39D6AFC	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	intact-crc:173ED1A3CEE40AA5|rigid:XTgYp4gRUkvEewGnYnWKS5Jv9sU	false	protein a tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P53632	uniprotkb:P40507	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0096"(pull down)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209909|imex:IM-20232-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	crc64:8A58B29E4BFDC022	crc64:3CA920FA1204EC9C	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:173ED1A3CEE40AA5|rigid:XTgYp4gRUkvEewGnYnWKS5Jv9sU	false	protein a tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P15938	uniprotkb:P53632	intact:EBI-13829|ensemblfungi:YKR086W|uniprotkb:D6VXE6	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:prp16_yeast(display_long)|uniprotkb:PRP16(gene name)|psi-mi:PRP16(display_short)|uniprotkb:YKR406(orf name)|uniprotkb:YKR086W(locus name)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209926|imex:IM-20232-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKR086W(gene)|ensemblfungi:YKR086W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000378"(RNA exon ligation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0040031"(snRNA modification)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:5LJ5|rcsb pdb:5WSG|sgd:S000001794|refseq:NP_013012.3|mint:P15938|dip:DIP-2824N	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	-	crc64:8A58B29E4BFDC022	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:VqNrP9XJw1F9tua3l1D9XHyPOBM559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:68B49CB49FAFC3D0|rigid:Lwa+gA6+iMmaLHWd1dhqedaQED0	false	sufficient binding region:315-503	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53632	uniprotkb:P40507	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0018"(two hybrid)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2214751|imex:IM-20232-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	crc64:8A58B29E4BFDC022	crc64:3CA920FA1204EC9C	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:E8C86F12E94D33F8|rigid:EwKtuGxgyKNPZ5X44g/f6GCfE50	false	-	necessary binding region:127-149	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12476	uniprotkb:P53632	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2214759|imex:IM-20232-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	crc64:5915C97FA39D6AFC	crc64:8A58B29E4BFDC022	figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:016365180C5F37D0|rigid:srO1ANQePXxC6aLgCF280UXMc4k	false	necessary binding region:80-171	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:P47047	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209938|imex:IM-20232-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	-	crc64:3CA920FA1204EC9C	crc64:1FA9EAADC546F669	figure legend:Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	intact-crc:6ECA5D50781C0CC2|rigid:CPItvhwiBvb39pN6TgzZgHx+Q5M	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40507	uniprotkb:P53632	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209938|imex:IM-20232-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	crc64:3CA920FA1204EC9C	crc64:8A58B29E4BFDC022	figure legend:Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:6ECA5D50781C0CC2|rigid:CPItvhwiBvb39pN6TgzZgHx+Q5M	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12476	uniprotkb:P53632	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209951|imex:IM-20232-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	crc64:5915C97FA39D6AFC	crc64:8A58B29E4BFDC022	figure legend:Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:A50756F390BB94EA|rigid:k+gArezsdIFijSikL7XvHG5WRl0	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12476	uniprotkb:P47047	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209951|imex:IM-20232-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	-	crc64:5915C97FA39D6AFC	crc64:1FA9EAADC546F669	figure legend:Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	intact-crc:A50756F390BB94EA|rigid:k+gArezsdIFijSikL7XvHG5WRl0	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47047	uniprotkb:P53632	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209967|imex:IM-20232-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	crc64:1FA9EAADC546F669	crc64:8A58B29E4BFDC022	figure legend:Fig 3D, S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:D062EB8CBEBC60B3|rigid:Zs2zvEmMfSvGJkQiRjOnrWmtoDc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47047	uniprotkb:P53632	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	intact:EBI-19517|uniprotkb:D6W1V2|ensemblfungi:YOL115W	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:pap2_yeast(display_long)|uniprotkb:TRF4(gene name synonym)|uniprotkb:HRC584(orf name)|uniprotkb:O0716(orf name)|uniprotkb:YOL115W(locus name)|uniprotkb:PAP2(gene name)|psi-mi:PAP2(display_short)|uniprotkb:DNA polymerase sigma(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:Topoisomerase 1-related protein TRF4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209976|imex:IM-20232-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	refseq:NP_014526.1|sgd:S000005475|ensemblfungi:YOL115W(gene)|ensemblfungi:YOL115W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006400"(tRNA modification)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071047"(polyadenylation-dependent mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR043519|rcsb pdb:2MOW|rcsb pdb:4U4C|rcsb pdb:3NYB|dip:DIP-4214N|mint:P53632	-	crc64:1FA9EAADC546F669	crc64:8A58B29E4BFDC022	figure legend:Fig 3D, S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	rogid:ndWhFobdQrq5tf9WBXuA09dyMA0559292	intact-crc:549828126D500FF3|rigid:Zs2zvEmMfSvGJkQiRjOnrWmtoDc	false	-	calmodulin binding peptide plus protein a tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P48561	uniprotkb:P47047	intact:EBI-19525|uniprotkb:D6W0P5|ensemblfungi:YNL299W	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	psi-mi:trf5_yeast(display_long)|uniprotkb:TRF5(gene name)|psi-mi:TRF5(display_short)|uniprotkb:YNL299W(locus name)|uniprotkb:N0440(orf name)|uniprotkb:Topoisomerase 1-related protein TRF5(gene name synonym)	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209984|imex:IM-20232-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014100.2|sgd:S000005243|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR002058(PAP/25A-associated)|ensemblfungi:YNL299W(gene)|ensemblfungi:YNL299W_mRNA(transcript)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|mint:P48561|interpro:IPR043519	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	-	-	crc64:1FA9EAADC546F669	figure legend:Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:LGAMmHC1JOdurgO0HZ17ndGKZn8559292	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	intact-crc:8FECCEC15C86A266|rigid:W8c/A/M/3AmOKwBbzM/133F8gV8	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47047	uniprotkb:Q12149	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	intact:EBI-1782|uniprotkb:Q6B280|uniprotkb:D6W267|ensemblfungi:YOR001W	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:rrp6_yeast(display_long)|uniprotkb:RRP6(gene name)|psi-mi:RRP6(display_short)|uniprotkb:UNC733(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 6(gene name synonym)|uniprotkb:YOR001W(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Vanacova et al. (2005)	pubmed:15828860|imex:IM-20232	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2209993|imex:IM-20232-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	refseq:NP_014643.1|sgd:S000005527|dip:DIP-4560N|ensemblfungi:YOR001W(gene)|ensemblfungi:YOR001W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0071028"(nuclear mRNA surveillance)|mint:Q12149|go:"GO:0071033"|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|rcsb pdb:1M0Y|rcsb pdb:2HBJ|rcsb pdb:2HBK|rcsb pdb:2HBL|rcsb pdb:2HBM|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:4WFC|rcsb pdb:4WFD|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5C0Y|rcsb pdb:5K36|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|reactome:R-SCE-6791226	-	crc64:1FA9EAADC546F669	crc64:B19A0B2ED74C6DA7	figure legend:Fig S2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/16	2014/10/16	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	rogid:29oQaOEcqYSzOIn7B6hj29GvisU559292	intact-crc:29F984C710618669|rigid:D37lewQX/bzhhfyAfbORidvBjdk	false	-	calmodulin binding peptide plus protein a tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)