#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P26663 uniprotkb:Q62245 intact:EBI-6857429 intact:EBI-1693|uniprotkb:Q62244|ensembl:ENSMUSP00000067786 psi-mi:polg_hcvbk(display_long) psi-mi:sos1_mouse(display_long)|uniprotkb:Sos1(gene name)|psi-mi:Sos1(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Ferreon et al. (2005) pubmed:15767257|mint:MINT-7218650|doi:10.1074/jbc.M500422200 taxid:11105(hcvbk)|taxid:11105("Hepatitis C virus genotype 1b (isolate BK)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7535585|mint:MINT-7311962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR024350|interpro:IPR027417|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0055036"(virion membrane)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1A1Q|rcsb pdb:1BT7|rcsb pdb:1C2P|rcsb pdb:1CSJ|rcsb pdb:1CU1|rcsb pdb:1GX5|rcsb pdb:1GX6|rcsb pdb:1JXP|rcsb pdb:1NHU|rcsb pdb:1NHV|rcsb pdb:1NS3|rcsb pdb:1OS5|rcsb pdb:1QUV|rcsb pdb:2AWZ|rcsb pdb:2AX0|rcsb pdb:2AX1|rcsb pdb:2BRK|rcsb pdb:2BRL|rcsb pdb:2DXS|rcsb pdb:2GIQ|rcsb pdb:2GIR|rcsb pdb:2HAI|rcsb pdb:2HWH|rcsb pdb:2HWI|rcsb pdb:2I1R|rcsb pdb:2JC1|rcsb pdb:2O5D|rcsb pdb:2JC0|rcsb pdb:2WCX|rcsb pdb:2WHO|rcsb pdb:2WRM|rcsb pdb:2XWY|rcsb pdb:2ZKU|rcsb pdb:3BR9|rcsb pdb:3BSA|rcsb pdb:3BSC|rcsb pdb:3CDE|rcsb pdb:3CIZ|rcsb pdb:3CJ0|rcsb pdb:3CJ2|rcsb pdb:3CJ3|rcsb pdb:3CJ4|rcsb pdb:3CJ5|rcsb pdb:3CO9|rcsb pdb:3CVK|rcsb pdb:3CWJ|rcsb pdb:3D28|rcsb pdb:3D5M|rcsb pdb:3E51|rcsb pdb:3FQK|rcsb pdb:3FRZ|rcsb pdb:3G86|rcsb pdb:3GYN|rcsb pdb:3H2L|rcsb pdb:3H59|rcsb pdb:3H5S|rcsb pdb:3H5U|rcsb pdb:3H98|rcsb pdb:3IGV|rcsb pdb:3MF5|rcsb pdb:3RVB|rcsb pdb:3UA7|rcsb pdb:3UDL|rcsb pdb:3VQS|rcsb pdb:4A92|rcsb pdb:4B6E|rcsb pdb:4B6F|rcsb pdb:4B71|rcsb pdb:4B73|rcsb pdb:4B74|rcsb pdb:4B75|rcsb pdb:4B76|rcsb pdb:4DGV|rcsb pdb:4DGY|rcsb pdb:4EO6|rcsb pdb:4EO8|rcsb pdb:4IH5|rcsb pdb:4IH6|rcsb pdb:4IH7|rcsb pdb:4K8B|rcsb pdb:4KAI|rcsb pdb:4KB7|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|rcsb pdb:4KE5|rcsb pdb:4MIA|rcsb pdb:4MIB|rcsb pdb:4MK7|rcsb pdb:4MK8|rcsb pdb:4MK9|rcsb pdb:4MKA|rcsb pdb:4KBI|rcsb pdb:4MKB|rcsb pdb:4TN2|rcsb pdb:4WXP|rcsb pdb:5FPS|rcsb pdb:5FPT|rcsb pdb:5FPY|rcsb pdb:5KZP|rcsb pdb:5W2E|rcsb pdb:6MVP|rcsb pdb:6W4G|rcsb pdb:8OHM|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504|mint:P26663|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|mint:MINT-7311964(identity) refseq:NP_033257.2|dip:DIP-29230N|ensembl:ENSMUSG00000024241(gene)|ensembl:ENSMUST00000068714(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001942"(hair follicle development)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007296"(vitellogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1904693"(midbrain morphogenesis)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|mint:Q62245|rcsb pdb:1B07|rcsb pdb:1GBQ|rcsb pdb:1PMS|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-193648|reactome:R-MMU-1963640|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-416482|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8853659|reactome:R-MMU-8983432|reactome:R-MMU-9013149|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-9607240|reactome:R-MMU-983695|mint:MINT-7311965(identity) - - crc64:3286088A5BA0A4A6 comment:homomint|comment:mint|figure legend:f6a f6b|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/04 2014/10/16 rogid:LiDfjMVpPXRZ7h687NIgnXpY6Lc11105 rogid:n5Gaz6esU+5ryBPr8s91dizgMnE10090 intact-crc:740FBAFEFAB3A05E|rigid:jKE5CmK5BS9VW0s/h0QhZgeGI3M false binding-associated region:1047-1227(MINT-7311975) binding-associated region:1136-1144(MINT-7311970) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26663 uniprotkb:Q62245 intact:EBI-6857429 intact:EBI-1693|uniprotkb:Q62244|ensembl:ENSMUSP00000067786 psi-mi:polg_hcvbk(display_long) psi-mi:sos1_mouse(display_long)|uniprotkb:Sos1(gene name)|psi-mi:Sos1(display_short) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Ferreon et al. (2005) pubmed:15767257|mint:MINT-7218650|doi:10.1074/jbc.M500422200 taxid:11105(hcvbk)|taxid:11105("Hepatitis C virus genotype 1b (isolate BK)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7535667|mint:MINT-7311978 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR024350|interpro:IPR027417|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0055036"(virion membrane)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1A1Q|rcsb pdb:1BT7|rcsb pdb:1C2P|rcsb pdb:1CSJ|rcsb pdb:1CU1|rcsb pdb:1GX5|rcsb pdb:1GX6|rcsb pdb:1JXP|rcsb pdb:1NHU|rcsb pdb:1NHV|rcsb pdb:1NS3|rcsb pdb:1OS5|rcsb pdb:1QUV|rcsb pdb:2AWZ|rcsb pdb:2AX0|rcsb pdb:2AX1|rcsb pdb:2BRK|rcsb pdb:2BRL|rcsb pdb:2DXS|rcsb pdb:2GIQ|rcsb pdb:2GIR|rcsb pdb:2HAI|rcsb pdb:2HWH|rcsb pdb:2HWI|rcsb pdb:2I1R|rcsb pdb:2JC1|rcsb pdb:2O5D|rcsb pdb:2JC0|rcsb pdb:2WCX|rcsb pdb:2WHO|rcsb pdb:2WRM|rcsb pdb:2XWY|rcsb pdb:2ZKU|rcsb pdb:3BR9|rcsb pdb:3BSA|rcsb pdb:3BSC|rcsb pdb:3CDE|rcsb pdb:3CIZ|rcsb pdb:3CJ0|rcsb pdb:3CJ2|rcsb pdb:3CJ3|rcsb pdb:3CJ4|rcsb pdb:3CJ5|rcsb pdb:3CO9|rcsb pdb:3CVK|rcsb pdb:3CWJ|rcsb pdb:3D28|rcsb pdb:3D5M|rcsb pdb:3E51|rcsb pdb:3FQK|rcsb pdb:3FRZ|rcsb pdb:3G86|rcsb pdb:3GYN|rcsb pdb:3H2L|rcsb pdb:3H59|rcsb pdb:3H5S|rcsb pdb:3H5U|rcsb pdb:3H98|rcsb pdb:3IGV|rcsb pdb:3MF5|rcsb pdb:3RVB|rcsb pdb:3UA7|rcsb pdb:3UDL|rcsb pdb:3VQS|rcsb pdb:4A92|rcsb pdb:4B6E|rcsb pdb:4B6F|rcsb pdb:4B71|rcsb pdb:4B73|rcsb pdb:4B74|rcsb pdb:4B75|rcsb pdb:4B76|rcsb pdb:4DGV|rcsb pdb:4DGY|rcsb pdb:4EO6|rcsb pdb:4EO8|rcsb pdb:4IH5|rcsb pdb:4IH6|rcsb pdb:4IH7|rcsb pdb:4K8B|rcsb pdb:4KAI|rcsb pdb:4KB7|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|rcsb pdb:4KE5|rcsb pdb:4MIA|rcsb pdb:4MIB|rcsb pdb:4MK7|rcsb pdb:4MK8|rcsb pdb:4MK9|rcsb pdb:4MKA|rcsb pdb:4KBI|rcsb pdb:4MKB|rcsb pdb:4TN2|rcsb pdb:4WXP|rcsb pdb:5FPS|rcsb pdb:5FPT|rcsb pdb:5FPY|rcsb pdb:5KZP|rcsb pdb:5W2E|rcsb pdb:6MVP|rcsb pdb:6W4G|rcsb pdb:8OHM|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504|mint:P26663|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|mint:MINT-7311980(identity) refseq:NP_033257.2|dip:DIP-29230N|ensembl:ENSMUSG00000024241(gene)|ensembl:ENSMUST00000068714(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001942"(hair follicle development)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007296"(vitellogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1904693"(midbrain morphogenesis)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|mint:Q62245|rcsb pdb:1B07|rcsb pdb:1GBQ|rcsb pdb:1PMS|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-193648|reactome:R-MMU-1963640|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-416482|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8853659|reactome:R-MMU-8983432|reactome:R-MMU-9013149|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-9607240|reactome:R-MMU-983695|mint:MINT-7311984(identity) - - crc64:3286088A5BA0A4A6 figure legend:f5a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/12/04 2014/10/16 rogid:LiDfjMVpPXRZ7h687NIgnXpY6Lc11105 rogid:n5Gaz6esU+5ryBPr8s91dizgMnE10090 intact-crc:6EED3CE80AC783D3|rigid:jKE5CmK5BS9VW0s/h0QhZgeGI3M false binding-associated region:1047-1227(MINT-7311981) binding-associated region:1136-1144(MINT-7311985) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)