#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15498	uniprotkb:P78314	intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym)	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:"MI:0018"(two hybrid)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7314971|mint:MINT-7301258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N|mint:MINT-7301261(identity)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301260(identity)	-	-	-	figure legend:f2a|comment:homomint|comment:domino|comment:mint|comment:3BP2 taxid has not been specified	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/11/18	2014/10/16	rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	intact-crc:CE230391999B518D|rigid:tqwbeQBpMocQtGpUygj7qY4kzaA	false	binding-associated region:?-?(MINT-7301266)|tag:?-?(MINT-7301263)	tag:?-?(MINT-7301270)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P52735	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:"MI:0018"(two hybrid)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315012|mint:MINT-7301276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301285(identity)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|mint:MINT-7301278(identity)	-	-	-	figure legend:f2a|comment:homomint|comment:domino|comment:mint|comment:3BP2 taxid has not been specified	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	intact-crc:F61F7B42A8809037|rigid:FkszY1IL30WTqwz1kihTFsbyhwc	false	tag:?-?(MINT-7301286)	tag:?-?(MINT-7301282)|binding-associated region:513-868(MINT-7301279)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P52735	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315097|mint:MINT-7301295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301304(identity)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|mint:MINT-7301297(identity)	-	-	-	comment:homomint|comment:domino|comment:mint|comment:proteins taxid has not been specified|figure legend:f2b f4c	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	intact-crc:CE1650432C5BDDE0|rigid:FkszY1IL30WTqwz1kihTFsbyhwc	false	ha tag:?-?(MINT-7301305)|binding-associated region:201-240(MINT-7301453)	myc tag:?-?(MINT-7301298)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P15498	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315287|mint:MINT-7301313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301315(identity)	go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N|mint:MINT-7301319(identity)	-	-	-	comment:homomint|comment:domino|comment:mint|comment:proteins taxid has not been specified|figure legend:f2b f4b	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606	intact-crc:2AC985E7D8F52F66|rigid:tqwbeQBpMocQtGpUygj7qY4kzaA	false	binding-associated region:201-240(MINT-7301447)|ha tag:?-?(MINT-7301316)	myc tag:?-?(MINT-7301320)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:Q9UKW4	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-297568|uniprotkb:O95230|uniprotkb:Q9Y5X8|uniprotkb:B1APV5|uniprotkb:B1AMM0|uniprotkb:B4E232|uniprotkb:B7ZLR1|uniprotkb:E9PQ97|uniprotkb:O60498|ensembl:ENSP00000359073	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:vav3_human(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315310|mint:MINT-7301329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301335(identity)	refseq:NP_001073343.1|refseq:NP_006104.4|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035734|interpro:IPR035881|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q9UKW4|rcsb pdb:2D86|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|ensembl:ENSG00000134215(gene)|ensembl:ENST00000370056(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001772"(immunological synapse)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042493"|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|refseq:XP_005270417.1|mint:MINT-7301331(identity)	-	-	-	figure legend:f2c|comment:homomint|comment:mint|comment:proteins taxid has not been specified	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606	intact-crc:2EB75DB517F0243E|rigid:9BKb37ei98zPe0RMKZYuDj20z6g	false	ha tag:?-?(MINT-7301336)	myc tag:?-?(MINT-7301332)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P19174	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315362|mint:MINT-7301369	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301373(identity)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|mint:MINT-7301381(identity)	-	-	-	figure legend:f3d|comment:homomint|comment:domino|comment:mint|comment:3BP2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	intact-crc:451E1F76C05FBECF|rigid:DbzMs6Mqpbq1qUvv8lxNa4Tpjs4	false	glutathione s tranferase tag:?-?(MINT-7301391)|binding-associated region:455-553(MINT-7301393)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P43405	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-78302|ensembl:ENSP00000364898|ensembl:ENSP00000364907	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:ksyk_human(display_long)|uniprotkb:SYK(gene name)|psi-mi:SYK(display_short)|uniprotkb:Spleen tyrosine kinase(gene name synonym)|uniprotkb:p72-Syk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315362|mint:MINT-7301369	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301373(identity)	refseq:NP_001128524.1|refseq:NP_001167638.1|refseq:NP_001167639.1|refseq:NP_003168.2|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043313"(regulation of neutrophil degranulation)|go:"GO:0043366"(beta selection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071226"(cellular response to molecule of fungal origin)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090237"(regulation of arachidonic acid secretion)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990858"(cellular response to lectin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43405|rcsb pdb:1A81|rcsb pdb:1CSY|rcsb pdb:1CSZ|rcsb pdb:1XBA|rcsb pdb:1XBB|rcsb pdb:1XBC|rcsb pdb:3BUW|rcsb pdb:3EMG|rcsb pdb:3FQE|rcsb pdb:3FQH|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019815"(B cell receptor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032009"(early phagosome)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032752"(positive regulation of interleukin-3 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032928"(regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0016170"(interleukin-15 receptor binding)|rcsb pdb:3FQS|rcsb pdb:3SRV|rcsb pdb:3TUB|rcsb pdb:3TUC|rcsb pdb:3TUD|rcsb pdb:3VF8|rcsb pdb:3VF9|rcsb pdb:4DFL|rcsb pdb:4DFN|rcsb pdb:4F4P|rcsb pdb:4FL1|rcsb pdb:4FL2|rcsb pdb:4FL3|rcsb pdb:4FYN|rcsb pdb:4FYO|rcsb pdb:4FZ6|rcsb pdb:4FZ7|rcsb pdb:4GFG|rcsb pdb:4I0R|ensembl:ENSG00000165025(gene)|ensembl:ENST00000375746(transcript)|ensembl:ENST00000375754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|rcsb pdb:4I0S|rcsb pdb:4I0T|rcsb pdb:4PUZ|rcsb pdb:4PV0|rcsb pdb:4PX6|rcsb pdb:4RSS|rcsb pdb:4RX7|rcsb pdb:4RX8|rcsb pdb:4RX9|rcsb pdb:4WNM|rcsb pdb:4XG2|rcsb pdb:4XG3|rcsb pdb:5TIU|rcsb pdb:5TR6|rcsb pdb:5TT7|rcsb pdb:5Y5T|rcsb pdb:5Y5U|rcsb pdb:6HM6|rcsb pdb:6HM7|rcsb pdb:6SSB|rcsb pdb:6VOV|rcsb pdb:6ZC0|rcsb pdb:6ZCP|rcsb pdb:6ZCQ|rcsb pdb:6ZCR|rcsb pdb:6ZCS|rcsb pdb:6ZCU|rcsb pdb:6ZCX|rcsb pdb:6ZCY|rcsb pdb:4XG4|reactome:R-HSA-114604|reactome:R-HSA-2029481|reactome:R-HSA-2029482|rcsb pdb:4XG7|rcsb pdb:4XG8|rcsb pdb:4XG9|rcsb pdb:4YJO|rcsb pdb:4YJP|rcsb pdb:4YJQ|rcsb pdb:4YJR|rcsb pdb:4YJS|rcsb pdb:4YJT|rcsb pdb:4YJU|rcsb pdb:4YJV|rcsb pdb:5C26|rcsb pdb:5C27|rcsb pdb:5CXH|rcsb pdb:5CXZ|rcsb pdb:5CY3|rcsb pdb:5GHV|rcsb pdb:5LMA|rcsb pdb:4XG6|rcsb pdb:5LMB|rcsb pdb:5T68|refseq:XP_011517248.1|refseq:XP_005252204.1|reactome:R-HSA-2029485|reactome:R-HSA-2424491|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-5607764|reactome:R-HSA-5621480|reactome:R-HSA-9020558|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|reactome:R-HSA-983695|dip:DIP-253N|mint:MINT-7301382(identity)	-	-	-	figure legend:f3d|comment:homomint|comment:domino|comment:mint|comment:3BP2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:SAOtCMFKG07Wej573EklHjusYVA9606	intact-crc:451E1F76C05FBECF|rigid:DbzMs6Mqpbq1qUvv8lxNa4Tpjs4	false	glutathione s tranferase tag:?-?(MINT-7301391)|binding-associated region:455-553(MINT-7301393)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78314	uniprotkb:P15498	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315362|mint:MINT-7301369	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301373(identity)	go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N|mint:MINT-7301371(identity)	-	-	-	figure legend:f3d|comment:homomint|comment:domino|comment:mint|comment:3BP2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606	intact-crc:451E1F76C05FBECF|rigid:DbzMs6Mqpbq1qUvv8lxNa4Tpjs4	false	glutathione s tranferase tag:?-?(MINT-7301391)|binding-associated region:455-553(MINT-7301393)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52735	uniprotkb:P22681	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315427|mint:MINT-7301412	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|mint:MINT-7301416(identity)	refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377|mint:MINT-7301414(identity)	-	-	-	figure legend:f3c|comment:homomint|comment:domino|comment:mint|comment:Vav2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	intact-crc:150E25059B0C79E9|rigid:8TWycfbvdt0BLCQWKQsxGc/hk9s	false	binding-associated region:513-868(MINT-7301432)|glutathione s tranferase tag:?-?(MINT-7301430)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52735	uniprotkb:P78314	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315427|mint:MINT-7301412	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|mint:MINT-7301416(identity)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301420(identity)	-	-	-	figure legend:f3c|comment:homomint|comment:domino|comment:mint|comment:Vav2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	intact-crc:150E25059B0C79E9|rigid:8TWycfbvdt0BLCQWKQsxGc/hk9s	false	binding-associated region:513-868(MINT-7301432)|glutathione s tranferase tag:?-?(MINT-7301430)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52735	uniprotkb:P43405	intact:EBI-297549|ensembl:ENSP00000360916|uniprotkb:A2RUM4|uniprotkb:A8MQ12|uniprotkb:Q5SYV3|uniprotkb:Q5SYV4|uniprotkb:Q5SYV5|uniprotkb:Q6N012|uniprotkb:Q6PIJ9|uniprotkb:Q6Q317|uniprotkb:B6ZDF5	intact:EBI-78302|ensembl:ENSP00000364898|ensembl:ENSP00000364907	psi-mi:vav2_human(display_long)|uniprotkb:VAV2(gene name)|psi-mi:VAV2(display_short)	psi-mi:ksyk_human(display_long)|uniprotkb:SYK(gene name)|psi-mi:SYK(display_short)|uniprotkb:Spleen tyrosine kinase(gene name synonym)|uniprotkb:p72-Syk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315427|mint:MINT-7301412	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160293(gene)|ensembl:ENST00000371850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030168"(platelet activation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P52735|rcsb pdb:2DLZ|rcsb pdb:2DM1|rcsb pdb:2LNW|rcsb pdb:2LNX|rcsb pdb:4ROJ|reactome:R-HSA-114604|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2424491|reactome:R-HSA-2871796|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|reactome:R-HSA-2871809|reactome:R-HSA-3928665|reactome:R-HSA-416482|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|reactome:R-HSA-4420097|refseq:NP_001127870.1|refseq:NP_003362.2|refseq:XP_005272270.1|dip:DIP-33088N|mint:MINT-7301416(identity)	refseq:NP_001128524.1|refseq:NP_001167638.1|refseq:NP_001167639.1|refseq:NP_003168.2|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043313"(regulation of neutrophil degranulation)|go:"GO:0043366"(beta selection)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071226"(cellular response to molecule of fungal origin)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090237"(regulation of arachidonic acid secretion)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990858"(cellular response to lectin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43405|rcsb pdb:1A81|rcsb pdb:1CSY|rcsb pdb:1CSZ|rcsb pdb:1XBA|rcsb pdb:1XBB|rcsb pdb:1XBC|rcsb pdb:3BUW|rcsb pdb:3EMG|rcsb pdb:3FQE|rcsb pdb:3FQH|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019815"(B cell receptor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032009"(early phagosome)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032752"(positive regulation of interleukin-3 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032928"(regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0016170"(interleukin-15 receptor binding)|rcsb pdb:3FQS|rcsb pdb:3SRV|rcsb pdb:3TUB|rcsb pdb:3TUC|rcsb pdb:3TUD|rcsb pdb:3VF8|rcsb pdb:3VF9|rcsb pdb:4DFL|rcsb pdb:4DFN|rcsb pdb:4F4P|rcsb pdb:4FL1|rcsb pdb:4FL2|rcsb pdb:4FL3|rcsb pdb:4FYN|rcsb pdb:4FYO|rcsb pdb:4FZ6|rcsb pdb:4FZ7|rcsb pdb:4GFG|rcsb pdb:4I0R|ensembl:ENSG00000165025(gene)|ensembl:ENST00000375746(transcript)|ensembl:ENST00000375754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001775"(cell activation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002366"(leukocyte activation involved in immune response)|go:"GO:0002554"(serotonin secretion by platelet)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|rcsb pdb:4I0S|rcsb pdb:4I0T|rcsb pdb:4PUZ|rcsb pdb:4PV0|rcsb pdb:4PX6|rcsb pdb:4RSS|rcsb pdb:4RX7|rcsb pdb:4RX8|rcsb pdb:4RX9|rcsb pdb:4WNM|rcsb pdb:4XG2|rcsb pdb:4XG3|rcsb pdb:5TIU|rcsb pdb:5TR6|rcsb pdb:5TT7|rcsb pdb:5Y5T|rcsb pdb:5Y5U|rcsb pdb:6HM6|rcsb pdb:6HM7|rcsb pdb:6SSB|rcsb pdb:6VOV|rcsb pdb:6ZC0|rcsb pdb:6ZCP|rcsb pdb:6ZCQ|rcsb pdb:6ZCR|rcsb pdb:6ZCS|rcsb pdb:6ZCU|rcsb pdb:6ZCX|rcsb pdb:6ZCY|rcsb pdb:4XG4|reactome:R-HSA-114604|reactome:R-HSA-2029481|reactome:R-HSA-2029482|rcsb pdb:4XG7|rcsb pdb:4XG8|rcsb pdb:4XG9|rcsb pdb:4YJO|rcsb pdb:4YJP|rcsb pdb:4YJQ|rcsb pdb:4YJR|rcsb pdb:4YJS|rcsb pdb:4YJT|rcsb pdb:4YJU|rcsb pdb:4YJV|rcsb pdb:5C26|rcsb pdb:5C27|rcsb pdb:5CXH|rcsb pdb:5CXZ|rcsb pdb:5CY3|rcsb pdb:5GHV|rcsb pdb:5LMA|rcsb pdb:4XG6|rcsb pdb:5LMB|rcsb pdb:5T68|refseq:XP_011517248.1|refseq:XP_005252204.1|reactome:R-HSA-2029485|reactome:R-HSA-2424491|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354192|reactome:R-HSA-5607764|reactome:R-HSA-5621480|reactome:R-HSA-9020558|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9706374|reactome:R-HSA-983695|dip:DIP-253N|mint:MINT-7301418(identity)	-	-	-	figure legend:f3c|comment:homomint|comment:domino|comment:mint|comment:Vav2 taxid has not been specified.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/11/18	2014/10/16	rogid:usp18HylJidh6mU3Zf0cAzo5ABM9606	rogid:SAOtCMFKG07Wej573EklHjusYVA9606	intact-crc:150E25059B0C79E9|rigid:8TWycfbvdt0BLCQWKQsxGc/hk9s	false	binding-associated region:513-868(MINT-7301432)|glutathione s tranferase tag:?-?(MINT-7301430)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15498	uniprotkb:P78314	intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym)	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315462|mint:MINT-7301343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N|mint:MINT-7301345(identity)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301349(identity)	-	-	-	figure legend:f3a|comment:homomint|comment:mint	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2009/11/18	2014/10/16	rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	intact-crc:AEFF651449FB3D25|rigid:tqwbeQBpMocQtGpUygj7qY4kzaA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15498	uniprotkb:P78314	intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6	intact:EBI-727062|uniprotkb:O00500|uniprotkb:O15373|uniprotkb:P78315|uniprotkb:A6NNC2|uniprotkb:B2R5R6|uniprotkb:B4DT04|uniprotkb:D3DVR0|intact:EBI-28985856|ensembl:ENSP00000348685|ensembl:ENSP00000422168|uniprotkb:D6R919	psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym)	psi-mi:3bp2_human(display_long)|uniprotkb:SH3BP2(gene name)|psi-mi:SH3BP2(display_short)|uniprotkb:3BP2(gene name synonym)|uniprotkb:RES4-23(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Foucault et al. (2005)	pubmed:15345594|mint:MINT-7219191|doi:10.1182/blood-2003-08-2965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7315473|mint:MINT-7301359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N|mint:MINT-7301363(identity)	refseq:NP_001116153.1|refseq:NP_001139327.1|refseq:NP_001139328.1|refseq:NP_003014.3|ensembl:ENSP00000348685|ensembl:ENST00000435136|ensembl:ENSP00000403231|ensembl:ENSP00000422168|ensembl:ENST00000511747|ensembl:ENSP00000424846|ensembl:ENST00000513020|ensembl:ENSP00000424072|ensembl:ENST00000515737|ensembl:ENSP00000422605|ensembl:ENSG00000087266(gene)|ensembl:ENST00000356331(transcript)|ensembl:ENST00000503393(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035847|interpro:IPR035848|interpro:IPR036860|mint:P78314|rcsb pdb:2CR4|rcsb pdb:3TWR|mint:MINT-7301361(identity)	-	-	-	figure legend:f3b|comment:homomint|comment:mint	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2009/11/18	2014/10/16	rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606	rogid:W+/geQfSvLlQA6UvDPYN4zQCzh89606	intact-crc:EB15C5A4CD531EB4|rigid:tqwbeQBpMocQtGpUygj7qY4kzaA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)