#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62245	uniprotkb:P29355	intact:EBI-1693|uniprotkb:Q62244|ensembl:ENSMUSP00000067786	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:sos1_mouse(display_long)|uniprotkb:Sos1(gene name)|psi-mi:Sos1(display_short)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139421|mint:MINT-7385442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033257.2|dip:DIP-29230N|ensembl:ENSMUSG00000024241(gene)|ensembl:ENSMUST00000068714(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001942"(hair follicle development)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007296"(vitellogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1904693"(midbrain morphogenesis)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|mint:Q62245|rcsb pdb:1B07|rcsb pdb:1GBQ|rcsb pdb:1PMS|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-193648|reactome:R-MMU-1963640|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-416482|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8853659|reactome:R-MMU-8983432|reactome:R-MMU-9013149|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-9607240|reactome:R-MMU-983695|mint:MINT-7385445(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385444(identity)	-	crc64:3286088A5BA0A4A6	-	figure legend:t1|comment:homomint|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:190.0x10^-6(molar)	2009/12/17	2014/10/16	rogid:n5Gaz6esU+5ryBPr8s91dizgMnE10090	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:0FF006674C2F1B6D|rigid:CE/Hux+c6rMtZQl0McBfYvfsCvs	false	binding-associated region:1136-1142(MINT-7385455)	binding-associated region:155-214(MINT-7385449)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139453	uniprotkb:P29355	intact:MINT-7385477	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:pp-g4-l(display_short)|psi-mi:EBI-7139453(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139446|mint:MINT-7385461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385479(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385469(identity)	-	comment:mint|no-uniprot-update:	-	figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.048x10^-6(molar)	2009/12/17	2014/10/16	rogid:JEDEfn4/15p1vnqoTIQhzrvuT6g-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:CA653136C7AC7B72|rigid:m4p40MBFNhkHFntO1iroM4oG9xQ	false	-	binding-associated region:155-214(MINT-7385470)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139490	uniprotkb:P29355	intact:MINT-7385512	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:g4-l(display_short)|psi-mi:EBI-7139490(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139495|mint:MINT-7385500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385514(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385505(identity)	-	comment:mint|no-uniprot-update:	-	figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.6x10^-6(molar)	2009/12/17	2014/10/16	rogid:As372uMXjrCt+kJe8yNUZFJ4aK8-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:C45A88EA06898AC2|rigid:/GW1d3Cj/EAIpWKgJxezxcXsOTc	false	-	binding-associated region:155-214(MINT-7385506)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139468	uniprotkb:P29355	intact:MINT-7385494	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:pp-g3-l(display_short)|psi-mi:EBI-7139468(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139473|mint:MINT-7385482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385496(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385487(identity)	-	comment:mint|no-uniprot-update:	-	figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.025x10^-6(molar)	2009/12/17	2014/10/16	rogid:PbAipvD37bm9suAU99XYNwczVOk-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:2E4F980375E148F4|rigid:UEsKAnUfnmQ4x/pHSNDdfOEM0v4	false	-	binding-associated region:155-214(MINT-7385488)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139534	uniprotkb:P29355	intact:MINT-7385530	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:l(display_short)|psi-mi:EBI-7139534(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139527|mint:MINT-7385517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385532(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385522(identity)	-	comment:mint|no-uniprot-update:	-	figure legend:t1|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.936x10^-6(molar)	2009/12/17	2014/10/16	rogid:WXmnmQ3InTy8D/6uauN6pFfIuKw-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:5B675419909F9DA3|rigid:tEJgZp35ExsTWLcw7aplgz5omWg	false	-	binding-associated region:155-214(MINT-7385523)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139453	uniprotkb:P29355	intact:MINT-7385477	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:pp-g4-l(display_short)|psi-mi:EBI-7139453(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139579|mint:MINT-7385536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385539(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385541(identity)	-	comment:mint|no-uniprot-update:	-	comment:domino|comment:mint|figure legend:f1 f2b f3c|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/17	2014/10/16	rogid:JEDEfn4/15p1vnqoTIQhzrvuT6g-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:22383574B4968CCC|rigid:m4p40MBFNhkHFntO1iroM4oG9xQ	false	-	binding-associated region:155-214(MINT-7385542)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7139534	uniprotkb:P29355	intact:MINT-7385530	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:l(display_short)|psi-mi:EBI-7139534(display_long)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139706|mint:MINT-7385570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-7385573(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385575(identity)	-	comment:mint|no-uniprot-update:	-	figure legend:f2c|comment:domino|comment:mint|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/17	2014/10/16	rogid:WXmnmQ3InTy8D/6uauN6pFfIuKw-2	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:32694F45D41C9F3F|rigid:tEJgZp35ExsTWLcw7aplgz5omWg	false	-	binding-associated region:155-214(MINT-7385576)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62245	uniprotkb:P29355	intact:EBI-1693|uniprotkb:Q62244|ensembl:ENSMUSP00000067786	intact:EBI-315286|ensemblmetazoa:C14F5.5.1	psi-mi:sos1_mouse(display_long)|uniprotkb:Sos1(gene name)|psi-mi:Sos1(display_short)	psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ferguson et al. (2004)	pubmed:14978303|mint:MINT-7219510|doi:10.1110/ps.03470504	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7139608|mint:MINT-7385553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033257.2|dip:DIP-29230N|ensembl:ENSMUSG00000024241(gene)|ensembl:ENSMUST00000068714(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001942"(hair follicle development)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007296"(vitellogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1904693"(midbrain morphogenesis)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|mint:Q62245|rcsb pdb:1B07|rcsb pdb:1GBQ|rcsb pdb:1PMS|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-193648|reactome:R-MMU-1963640|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-416482|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5673001|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8853659|reactome:R-MMU-8983432|reactome:R-MMU-9013149|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-9607240|reactome:R-MMU-983695|mint:MINT-7385556(identity)	refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|mint:MINT-7385561(identity)	-	crc64:3286088A5BA0A4A6	-	comment:homomint|comment:domino|comment:mint|figure legend:f2a f3a|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/17	2014/10/16	rogid:n5Gaz6esU+5ryBPr8s91dizgMnE10090	rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239	intact-crc:8C24313D9FC22D0D|rigid:CE/Hux+c6rMtZQl0McBfYvfsCvs	false	binding-associated region:1136-1142(MINT-7385557)	binding-associated region:155-214(MINT-7385562)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)