#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P05113 uniprotkb:Q01344 intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454 intact:EBI-1759442|uniprotkb:Q6ISX9|uniprotkb:Q14633|uniprotkb:Q15469|uniprotkb:B4E2G0|uniprotkb:B3IU77|ensembl:ENSP00000256452|ensembl:ENSP00000412209 psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym) psi-mi:il5ra_human(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:CDw125(gene name synonym) psi-mi:"MI:0440"(saturation binding) Tavernier et al. (1992) pubmed:1495999|imex:IM-20370 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435830|imex:IM-20370-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 refseq:NP_001230028.1|refseq:NP_000555.2|refseq:NP_783851.1|refseq:NP_783852.1|refseq:NP_783853.1|refseq:NP_783854.1|refseq:NP_783855.1|dip:DIP-3510N|ensembl:ENSG00000091181(gene)|ensembl:ENST00000256452(transcript)|ensembl:ENST00000446632(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004914"(interleukin-5 receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032674"(regulation of interleukin-5 production)|go:"GO:0043235"(receptor complex)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:1OBX|rcsb pdb:1OBZ|rcsb pdb:3QT2|rcsb pdb:3VA2|rcsb pdb:6H41|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 - - - figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/16 2014/10/16 rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606 rogid:i24aGKbsW1miS4SgLpfiJjR1yvo9606 intact-crc:E12FA54C33AA4800|rigid:N9H9e+RrDyK6kuVOBDtvSoZdY4M false 125i radiolabel:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P32927 uniprotkb:P05113 intact:EBI-1809771|uniprotkb:Q5JZI1|uniprotkb:Q6ICE0|ensembl:ENSP00000384053 intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454 psi-mi:il3rb_human(display_long)|uniprotkb:CSF2RB(gene name)|psi-mi:CSF2RB(display_short)|uniprotkb:IL3RB(gene name synonym)|uniprotkb:IL5RB(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)|uniprotkb:CDw131(gene name synonym) psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym) psi-mi:"MI:0440"(saturation binding) Tavernier et al. (1992) pubmed:1495999|imex:IM-20370 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435838|imex:IM-20370-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000386.1|refseq:XP_005261397.1|dip:DIP-127N|ensembl:ENSG00000100368(gene)|ensembl:ENST00000403662(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030526"(granulocyte macrophage colony-stimulating factor receptor complex)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038043"(interleukin-5-mediated signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|rcsb pdb:1C8P|rcsb pdb:1EGJ|rcsb pdb:1GH7|rcsb pdb:2GYS|rcsb pdb:2NA8|rcsb pdb:2NA9|rcsb pdb:4NKQ|rcsb pdb:5DWU|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-5683826|reactome:R-HSA-5688849|reactome:R-HSA-5688890|reactome:R-HSA-912526 refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 - - - figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/16 2014/10/16 rogid:NZgW441MxxYgvAaUOGnwbuyj6uw9606 rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606 intact-crc:A466E6F47D5B7548|rigid:cvnn5ursyKAjFRt+Q5P2bfzbp3I false - 125i radiolabel:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P32927 uniprotkb:Q01344 intact:EBI-1809771|uniprotkb:Q5JZI1|uniprotkb:Q6ICE0|ensembl:ENSP00000384053 intact:EBI-1759442|uniprotkb:Q6ISX9|uniprotkb:Q14633|uniprotkb:Q15469|uniprotkb:B4E2G0|uniprotkb:B3IU77|ensembl:ENSP00000256452|ensembl:ENSP00000412209 psi-mi:il3rb_human(display_long)|uniprotkb:CSF2RB(gene name)|psi-mi:CSF2RB(display_short)|uniprotkb:IL3RB(gene name synonym)|uniprotkb:IL5RB(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)|uniprotkb:CDw131(gene name synonym) psi-mi:il5ra_human(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:CDw125(gene name synonym) psi-mi:"MI:0440"(saturation binding) Tavernier et al. (1992) pubmed:1495999|imex:IM-20370 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435838|imex:IM-20370-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000386.1|refseq:XP_005261397.1|dip:DIP-127N|ensembl:ENSG00000100368(gene)|ensembl:ENST00000403662(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030526"(granulocyte macrophage colony-stimulating factor receptor complex)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038043"(interleukin-5-mediated signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|rcsb pdb:1C8P|rcsb pdb:1EGJ|rcsb pdb:1GH7|rcsb pdb:2GYS|rcsb pdb:2NA8|rcsb pdb:2NA9|rcsb pdb:4NKQ|rcsb pdb:5DWU|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-5683826|reactome:R-HSA-5688849|reactome:R-HSA-5688890|reactome:R-HSA-912526 refseq:NP_001230028.1|refseq:NP_000555.2|refseq:NP_783851.1|refseq:NP_783852.1|refseq:NP_783853.1|refseq:NP_783854.1|refseq:NP_783855.1|dip:DIP-3510N|ensembl:ENSG00000091181(gene)|ensembl:ENST00000256452(transcript)|ensembl:ENST00000446632(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004914"(interleukin-5 receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032674"(regulation of interleukin-5 production)|go:"GO:0043235"(receptor complex)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:1OBX|rcsb pdb:1OBZ|rcsb pdb:3QT2|rcsb pdb:3VA2|rcsb pdb:6H41|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 - - - figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/16 2014/10/16 rogid:NZgW441MxxYgvAaUOGnwbuyj6uw9606 rogid:i24aGKbsW1miS4SgLpfiJjR1yvo9606 intact-crc:A466E6F47D5B7548|rigid:cvnn5ursyKAjFRt+Q5P2bfzbp3I false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P05113 uniprotkb:P32927 intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454 intact:EBI-1809771|uniprotkb:Q5JZI1|uniprotkb:Q6ICE0|ensembl:ENSP00000384053 psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym) psi-mi:il3rb_human(display_long)|uniprotkb:CSF2RB(gene name)|psi-mi:CSF2RB(display_short)|uniprotkb:IL3RB(gene name synonym)|uniprotkb:IL5RB(gene name synonym)|uniprotkb:GM-CSF/IL-3/IL-5 receptor common beta subunit(gene name synonym)|uniprotkb:CDw131(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tavernier et al. (1992) pubmed:1495999|imex:IM-20370 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435871|imex:IM-20370-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 refseq:NP_000386.1|refseq:XP_005261397.1|dip:DIP-127N|ensembl:ENSG00000100368(gene)|ensembl:ENST00000403662(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030526"(granulocyte macrophage colony-stimulating factor receptor complex)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038043"(interleukin-5-mediated signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011365(Cytokine IL-3/IL-5/GM-CSF receptor common beta chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015373(Interferon-alpha/beta receptor, fibronectin type III)|interpro:IPR036116|rcsb pdb:1C8P|rcsb pdb:1EGJ|rcsb pdb:1GH7|rcsb pdb:2GYS|rcsb pdb:2NA8|rcsb pdb:2NA9|rcsb pdb:4NKQ|rcsb pdb:5DWU|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-5683826|reactome:R-HSA-5688849|reactome:R-HSA-5688890|reactome:R-HSA-912526 - - - figure legend:5b|comment:Cos cells were cotransfected with IL5R alpha.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/16 2014/10/16 rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606 rogid:NZgW441MxxYgvAaUOGnwbuyj6uw9606 intact-crc:DCA00C61DCED8723|rigid:RQs8fGIoWKBypRiFVrbUcQcuPr4 false 125i radiolabel:?-? - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q01344 uniprotkb:P05113 intact:EBI-1759442|uniprotkb:Q6ISX9|uniprotkb:Q14633|uniprotkb:Q15469|uniprotkb:B4E2G0|uniprotkb:B3IU77|ensembl:ENSP00000256452|ensembl:ENSP00000412209 intact:EBI-2435811|uniprotkb:Q13840|ensembl:ENSP00000231454 psi-mi:il5ra_human(display_long)|uniprotkb:IL5RA(gene name)|psi-mi:IL5RA(display_short)|uniprotkb:IL5R(gene name synonym)|uniprotkb:CDw125(gene name synonym) psi-mi:il5_human(display_long)|uniprotkb:IL5(gene name)|psi-mi:IL5(display_short)|uniprotkb:T-cell replacing factor(gene name synonym)|uniprotkb:Eosinophil differentiation factor(gene name synonym)|uniprotkb:B-cell differentiation factor I(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tavernier et al. (1992) pubmed:1495999|imex:IM-20370 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435881|imex:IM-20370-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230028.1|refseq:NP_000555.2|refseq:NP_783851.1|refseq:NP_783852.1|refseq:NP_783853.1|refseq:NP_783854.1|refseq:NP_783855.1|dip:DIP-3510N|ensembl:ENSG00000091181(gene)|ensembl:ENST00000256452(transcript)|ensembl:ENST00000446632(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004914"(interleukin-5 receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032674"(regulation of interleukin-5 production)|go:"GO:0043235"(receptor complex)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|interpro:IPR003532(Short hematopoietin receptor, family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|rcsb pdb:1OBX|rcsb pdb:1OBZ|rcsb pdb:3QT2|rcsb pdb:3VA2|rcsb pdb:6H41|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 refseq:XP_011541675.1|refseq:XP_011541676.1|refseq:NP_000870.1|dip:DIP-28N|ensembl:ENSG00000113525(gene)|ensembl:ENST00000231454(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005125"(cytokine activity)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008083"(growth factor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0045645"(positive regulation of eosinophil differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR000186(Interleukin-5)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1HUL|rcsb pdb:3QT2|rcsb pdb:3VA2|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-912526 - - - figure legend:5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/09/16 2014/10/16 rogid:i24aGKbsW1miS4SgLpfiJjR1yvo9606 rogid:XmPcnCcFxgGfHCIQY7LphdNRKMY9606 intact-crc:22D42CB4ACD73E73|rigid:N9H9e+RrDyK6kuVOBDtvSoZdY4M false - 125i radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)