#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35169 uniprotkb:P38873 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-24864|uniprotkb:D3DLD4|ensemblfungi:YHR186C psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:kog1_yeast(display_long)|uniprotkb:Kontroller of growth protein 1(gene name synonym)|uniprotkb:Local anesthetic-sensitive protein 24(gene name synonym)|uniprotkb:YHR186C(locus name)|uniprotkb:KOG1(gene name)|psi-mi:KOG1(display_short)|uniprotkb:LAS24(gene name synonym)|uniprotkb:H9998.14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434984|imex:IM-20365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 refseq:NP_012056.1|sgd:S000001229|mint:P38873|dip:DIP-2639N|ensemblfungi:YHR186C(gene)|ensemblfungi:YHR186C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|reactome:R-SCE-3371571|reactome:R-SCE-9639288 - crc64:ACB1781B9963BB1E crc64:B927EE93700176D3 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:8fDDVTuayLjREVAHrrpxJ9ExeCM559292 intact-crc:BEF33DFB644AC8F3|rigid:7E6ZpaDiVXHS/kvFKH6FB9EcMVc false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P35169 uniprotkb:Q08921 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-37395|uniprotkb:D6W3I8|ensemblfungi:YPL180W psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:tco89_yeast(display_long)|uniprotkb:YPL180W(locus name)|uniprotkb:TCO89(gene name)|psi-mi:TCO89(display_short)|uniprotkb:89 kDa TOR complex 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434984|imex:IM-20365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 refseq:NP_015145.1|sgd:S000006101|mint:Q08921|dip:DIP-5347N|ensemblfungi:YPL180W(gene)|ensemblfungi:YPL180W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0009651"(response to salt stress)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|interpro:IPR018857 - crc64:ACB1781B9963BB1E - figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:e5XaDahzdAGS+ynPYEbLZrSPFPE559292 intact-crc:BEF33DFB644AC8F3|rigid:7E6ZpaDiVXHS/kvFKH6FB9EcMVc false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P35169 uniprotkb:P32600 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434984|imex:IM-20365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 - crc64:ACB1781B9963BB1E crc64:F2349690146058CF figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 intact-crc:BEF33DFB644AC8F3|rigid:7E6ZpaDiVXHS/kvFKH6FB9EcMVc false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P35169 uniprotkb:P41318 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434984|imex:IM-20365-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK - crc64:ACB1781B9963BB1E crc64:536AA1DB8E8151F0 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 intact-crc:BEF33DFB644AC8F3|rigid:7E6ZpaDiVXHS/kvFKH6FB9EcMVc false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:P47041 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434993|imex:IM-20365-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757 - crc64:F2349690146058CF crc64:99F0F96840311F4B figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292 intact-crc:9FB2028DFFCE5CFD|rigid:6Bmiwv/6dtJr1+GRNN/eulLaU08 false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:Q04749 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-28131|uniprotkb:D6VZP2|ensemblfungi:YMR068W psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:avo2_yeast(display_long)|uniprotkb:YMR068W(locus name)|uniprotkb:YM9916.07(orf name)|uniprotkb:AVO2(gene name)|psi-mi:AVO2(display_short)|uniprotkb:Adheres voraciously to TOR2 protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434993|imex:IM-20365-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_013784.1|sgd:S000004672|dip:DIP-1958N|mint:Q04749|ensemblfungi:YMR068W(gene)|ensemblfungi:YMR068W_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|rcsb pdb:6EMK - crc64:F2349690146058CF - figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:T4jLsFiHINxRGduuu5DmqEPF3EE559292 intact-crc:9FB2028DFFCE5CFD|rigid:6Bmiwv/6dtJr1+GRNN/eulLaU08 false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:P40061 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-22621|uniprotkb:D3DM00|ensemblfungi:YER093C psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:tsc11_yeast(display_long)|uniprotkb:AVO3(gene name synonym)|uniprotkb:YER093C(locus name)|uniprotkb:TSC11(gene name)|psi-mi:TSC11(display_short)|uniprotkb:Adheres voraciously to TOR2 protein 3(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434993|imex:IM-20365-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_011018.1|sgd:S000000895|dip:DIP-4957N|mint:P40061|ensemblfungi:YER093C(gene)|ensemblfungi:YER093C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757 - crc64:F2349690146058CF crc64:07BB5D75BA204E50 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:VWXhP0KgrXl8YKFmjxSKYVJbMcQ559292 intact-crc:9FB2028DFFCE5CFD|rigid:6Bmiwv/6dtJr1+GRNN/eulLaU08 false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:P41318 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434993|imex:IM-20365-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK - crc64:F2349690146058CF crc64:536AA1DB8E8151F0 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 intact-crc:9FB2028DFFCE5CFD|rigid:6Bmiwv/6dtJr1+GRNN/eulLaU08 false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:Q08236 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-29284|uniprotkb:D6W1Y9|ensemblfungi:YOL078W psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:avo1_yeast(display_long)|uniprotkb:Adheres voraciously to TOR2 protein 1(gene name synonym)|uniprotkb:YOL078W(locus name)|uniprotkb:AVO1(gene name)|psi-mi:AVO1(display_short)|uniprotkb:O1110(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2434993|imex:IM-20365-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_014563.1|sgd:S000005438|dip:DIP-6357N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|ensemblfungi:YOL078W(gene)|ensemblfungi:YOL078W_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|interpro:IPR008828(Stress-activated map kinase interacting 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031313|interpro:IPR031567|rcsb pdb:3ULB|rcsb pdb:3ULC|rcsb pdb:6EMK - crc64:F2349690146058CF crc64:ED2B30D014EE5652 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:TzyrCBNOWYLrFV9+MUOnWXXvJYs559292 intact-crc:9FB2028DFFCE5CFD|rigid:6Bmiwv/6dtJr1+GRNN/eulLaU08 false ha tag:?-? - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P38873 uniprotkb:P41318 intact:EBI-24864|uniprotkb:D3DLD4|ensemblfungi:YHR186C intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W psi-mi:kog1_yeast(display_long)|uniprotkb:Kontroller of growth protein 1(gene name synonym)|uniprotkb:Local anesthetic-sensitive protein 24(gene name synonym)|uniprotkb:YHR186C(locus name)|uniprotkb:KOG1(gene name)|psi-mi:KOG1(display_short)|uniprotkb:LAS24(gene name synonym)|uniprotkb:H9998.14(orf name) psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435003|imex:IM-20365-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012056.1|sgd:S000001229|mint:P38873|dip:DIP-2639N|ensemblfungi:YHR186C(gene)|ensemblfungi:YHR186C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|reactome:R-SCE-3371571|reactome:R-SCE-9639288 reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK - crc64:B927EE93700176D3 crc64:536AA1DB8E8151F0 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:8fDDVTuayLjREVAHrrpxJ9ExeCM559292 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 intact-crc:19B91C12AAEB8903|rigid:LD1x6Wb5xEAT5glZCCkflWozExo false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P38873 uniprotkb:P35169 intact:EBI-24864|uniprotkb:D3DLD4|ensemblfungi:YHR186C intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W psi-mi:kog1_yeast(display_long)|uniprotkb:Kontroller of growth protein 1(gene name synonym)|uniprotkb:Local anesthetic-sensitive protein 24(gene name synonym)|uniprotkb:YHR186C(locus name)|uniprotkb:KOG1(gene name)|psi-mi:KOG1(display_short)|uniprotkb:LAS24(gene name synonym)|uniprotkb:H9998.14(orf name) psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435003|imex:IM-20365-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012056.1|sgd:S000001229|mint:P38873|dip:DIP-2639N|ensemblfungi:YHR186C(gene)|ensemblfungi:YHR186C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|reactome:R-SCE-3371571|reactome:R-SCE-9639288 refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 - crc64:B927EE93700176D3 crc64:ACB1781B9963BB1E figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:8fDDVTuayLjREVAHrrpxJ9ExeCM559292 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 intact-crc:19B91C12AAEB8903|rigid:LD1x6Wb5xEAT5glZCCkflWozExo false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P38873 uniprotkb:Q08921 intact:EBI-24864|uniprotkb:D3DLD4|ensemblfungi:YHR186C intact:EBI-37395|uniprotkb:D6W3I8|ensemblfungi:YPL180W psi-mi:kog1_yeast(display_long)|uniprotkb:Kontroller of growth protein 1(gene name synonym)|uniprotkb:Local anesthetic-sensitive protein 24(gene name synonym)|uniprotkb:YHR186C(locus name)|uniprotkb:KOG1(gene name)|psi-mi:KOG1(display_short)|uniprotkb:LAS24(gene name synonym)|uniprotkb:H9998.14(orf name) psi-mi:tco89_yeast(display_long)|uniprotkb:YPL180W(locus name)|uniprotkb:TCO89(gene name)|psi-mi:TCO89(display_short)|uniprotkb:89 kDa TOR complex 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435003|imex:IM-20365-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012056.1|sgd:S000001229|mint:P38873|dip:DIP-2639N|ensemblfungi:YHR186C(gene)|ensemblfungi:YHR186C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|reactome:R-SCE-3371571|reactome:R-SCE-9639288 refseq:NP_015145.1|sgd:S000006101|mint:Q08921|dip:DIP-5347N|ensemblfungi:YPL180W(gene)|ensemblfungi:YPL180W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0009651"(response to salt stress)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|interpro:IPR018857 - crc64:B927EE93700176D3 - figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:8fDDVTuayLjREVAHrrpxJ9ExeCM559292 rogid:e5XaDahzdAGS+ynPYEbLZrSPFPE559292 intact-crc:19B91C12AAEB8903|rigid:LD1x6Wb5xEAT5glZCCkflWozExo false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P41318 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK - crc64:536AA1DB8E8151F0 crc64:536AA1DB8E8151F0 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P38873 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-24864|uniprotkb:D3DLD4|ensemblfungi:YHR186C psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:kog1_yeast(display_long)|uniprotkb:Kontroller of growth protein 1(gene name synonym)|uniprotkb:Local anesthetic-sensitive protein 24(gene name synonym)|uniprotkb:YHR186C(locus name)|uniprotkb:KOG1(gene name)|psi-mi:KOG1(display_short)|uniprotkb:LAS24(gene name synonym)|uniprotkb:H9998.14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_012056.1|sgd:S000001229|mint:P38873|dip:DIP-2639N|ensemblfungi:YHR186C(gene)|ensemblfungi:YHR186C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|reactome:R-SCE-3371571|reactome:R-SCE-9639288 - crc64:536AA1DB8E8151F0 crc64:B927EE93700176D3 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:8fDDVTuayLjREVAHrrpxJ9ExeCM559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:Q08236 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-29284|uniprotkb:D6W1Y9|ensemblfungi:YOL078W psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:avo1_yeast(display_long)|uniprotkb:Adheres voraciously to TOR2 protein 1(gene name synonym)|uniprotkb:YOL078W(locus name)|uniprotkb:AVO1(gene name)|psi-mi:AVO1(display_short)|uniprotkb:O1110(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_014563.1|sgd:S000005438|dip:DIP-6357N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|ensemblfungi:YOL078W(gene)|ensemblfungi:YOL078W_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|interpro:IPR008828(Stress-activated map kinase interacting 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031313|interpro:IPR031567|rcsb pdb:3ULB|rcsb pdb:3ULC|rcsb pdb:6EMK - crc64:536AA1DB8E8151F0 crc64:ED2B30D014EE5652 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:TzyrCBNOWYLrFV9+MUOnWXXvJYs559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P32600 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 - crc64:536AA1DB8E8151F0 crc64:F2349690146058CF figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:Q08921 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-37395|uniprotkb:D6W3I8|ensemblfungi:YPL180W psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:tco89_yeast(display_long)|uniprotkb:YPL180W(locus name)|uniprotkb:TCO89(gene name)|psi-mi:TCO89(display_short)|uniprotkb:89 kDa TOR complex 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_015145.1|sgd:S000006101|mint:Q08921|dip:DIP-5347N|ensemblfungi:YPL180W(gene)|ensemblfungi:YPL180W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0009651"(response to salt stress)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|interpro:IPR018857 - crc64:536AA1DB8E8151F0 - figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:e5XaDahzdAGS+ynPYEbLZrSPFPE559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P35169 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 - crc64:536AA1DB8E8151F0 crc64:ACB1781B9963BB1E figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P47041 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757 - crc64:536AA1DB8E8151F0 crc64:99F0F96840311F4B figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:P40061 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-22621|uniprotkb:D3DM00|ensemblfungi:YER093C psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:tsc11_yeast(display_long)|uniprotkb:AVO3(gene name synonym)|uniprotkb:YER093C(locus name)|uniprotkb:TSC11(gene name)|psi-mi:TSC11(display_short)|uniprotkb:Adheres voraciously to TOR2 protein 3(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_011018.1|sgd:S000000895|dip:DIP-4957N|mint:P40061|ensemblfungi:YER093C(gene)|ensemblfungi:YER093C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757 - crc64:536AA1DB8E8151F0 crc64:07BB5D75BA204E50 figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:VWXhP0KgrXl8YKFmjxSKYVJbMcQ559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P41318 uniprotkb:Q04749 intact:EBI-28598|uniprotkb:D6W1H1|ensemblfungi:YNL006W intact:EBI-28131|uniprotkb:D6VZP2|ensemblfungi:YMR068W psi-mi:lst8_yeast(display_long)|uniprotkb:Lethal with SEC13 protein 8(gene name synonym)|uniprotkb:YNL006W(locus name)|uniprotkb:N2005(orf name)|uniprotkb:LST8(gene name)|psi-mi:LST8(display_short) psi-mi:avo2_yeast(display_long)|uniprotkb:YMR068W(locus name)|uniprotkb:YM9916.07(orf name)|uniprotkb:AVO2(gene name)|psi-mi:AVO2(display_short)|uniprotkb:Adheres voraciously to TOR2 protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435011|imex:IM-20365-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-3371571|sgd:S000004951|refseq:NP_014392.3|dip:DIP-5318N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YNL006W(gene)|ensemblfungi:YNL006W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034399"(nuclear periphery)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037588|rcsb pdb:6EMK refseq:NP_013784.1|sgd:S000004672|dip:DIP-1958N|mint:Q04749|ensemblfungi:YMR068W(gene)|ensemblfungi:YMR068W_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|rcsb pdb:6EMK - crc64:536AA1DB8E8151F0 - figure legend:Fig. 1, Table III|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:DJkTl61Tdn8EtP/6tE7UFerq8w0559292 rogid:T4jLsFiHINxRGduuu5DmqEPF3EE559292 intact-crc:E81BB1ACF3C4D342|rigid:lRv7sJ+JfkjYLzInUZo1PMl21z8 false ha tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32600 uniprotkb:P47041 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435031|imex:IM-20365-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757 - crc64:F2349690146058CF crc64:99F0F96840311F4B figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292 intact-crc:7011937A76E328D9|rigid:Mi1ONNMYVUDOPW1H9nLklzCMTy8 false ha tag:?-? myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q08921 uniprotkb:P35169 intact:EBI-37395|uniprotkb:D6W3I8|ensemblfungi:YPL180W intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W psi-mi:tco89_yeast(display_long)|uniprotkb:YPL180W(locus name)|uniprotkb:TCO89(gene name)|psi-mi:TCO89(display_short)|uniprotkb:89 kDa TOR complex 1 protein(gene name synonym) psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Reinke et al. (2004) pubmed:14736892|imex:IM-20365 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2435040|imex:IM-20365-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015145.1|sgd:S000006101|mint:Q08921|dip:DIP-5347N|ensemblfungi:YPL180W(gene)|ensemblfungi:YPL180W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0009651"(response to salt stress)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|interpro:IPR018857 refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 - - crc64:ACB1781B9963BB1E figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/09/04 2014/10/16 rogid:e5XaDahzdAGS+ynPYEbLZrSPFPE559292 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 intact-crc:93A1562A5641611D|rigid:/0tiaXy1duCR9a4VywhlNNa7/H4 false myc tag:c-c ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)