#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P19073	uniprotkb:P38785	intact:EBI-4274|uniprotkb:Q05978|uniprotkb:D6VYN1|ensemblfungi:YLR229C	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	psi-mi:cdc42_yeast(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:SRO2(gene name synonym)|uniprotkb:YLR229C(locus name)|uniprotkb:L8083.13(orf name)|uniprotkb:Suppressor of RHO3 protein 2(gene name synonym)	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:"MI:0018"(two hybrid)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132117|imex:IM-20214-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-862N|refseq:NP_013330.1|sgd:S000004219|mint:P19073|ensemblfungi:YLR229C(gene)|ensemblfungi:YLR229C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030031"(cell projection assembly)|go:"GO:0031106"(septin ring organization)|go:"GO:0031384"(regulation of initiation of mating projection growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0043332"(mating projection tip)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0071944"(cell periphery)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SCE-2029482|reactome:R-SCE-389359|reactome:R-SCE-5626467|reactome:R-SCE-5627123|reactome:R-SCE-5687128|reactome:R-SCE-9013148|reactome:R-SCE-9013406|reactome:R-SCE-9013409|reactome:R-SCE-983231	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	-	crc64:30BD644BA9836B2C	-	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/05	2014/10/16	rogid:4FDrNURFjSZOYUFf/dADXTpoMTc559292	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	intact-crc:3C3E81495C6879B1|rigid:+O+53AIl6gHOfrokHQKQCHI/ckY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47113	uniprotkb:P38785	intact:EBI-3586|uniprotkb:D6VWM4|ensemblfungi:YJR053W	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	psi-mi:bfa1_yeast(display_long)|uniprotkb:Cell cycle arrest protein BFA1(gene name synonym)|uniprotkb:BFA1(gene name)|psi-mi:BFA1(display_short)|uniprotkb:YJR053W(locus name)|uniprotkb:J1667(orf name)	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:"MI:0018"(two hybrid)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132121|imex:IM-20214-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003814|refseq:NP_012587.3|dip:DIP-4825N|mint:P47113|ensemblfungi:YJR053W(gene)|ensemblfungi:YJR053W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR034586	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	-	crc64:1EA75D26FCF041DA	-	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/05	2014/10/16	rogid:+J/c8Kt9mA/BgFlxHwBvNKuor5U559292	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	intact-crc:B4FDF60A6AD9A87C|rigid:Yt9zEBqed80WyNk5giyWZ7NJxWg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00684	uniprotkb:P38785	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:"MI:0018"(two hybrid)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132128|imex:IM-20214-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	-	crc64:4EB3985DFA3FD823	-	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/05	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	intact-crc:58B91B6829FA0965|rigid:8MHHTclZ/2fYHgbdU/ykknu+dyE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38785	uniprotkb:P26448	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132137|imex:IM-20214-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	-	-	crc64:A1DDBFB548E81EA3	figure legend:Fig 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/05	2014/10/16	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:E44743A926355813|rigid:KQE0C6xKBzUa0BRPX4FbyBbvMnk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38785	uniprotkb:Q00684	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132149|imex:IM-20214-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	-	-	crc64:4EB3985DFA3FD823	figure legend:Fig 3B, S1B|inhibition:Interaction is inhibited by NET1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:45B680D984DFC3E3|rigid:8MHHTclZ/2fYHgbdU/ykknu+dyE	false	glutathione s tranferase tag:n-n	maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38785	uniprotkb:P47113	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	intact:EBI-3586|uniprotkb:D6VWM4|ensemblfungi:YJR053W	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:bfa1_yeast(display_long)|uniprotkb:Cell cycle arrest protein BFA1(gene name synonym)|uniprotkb:BFA1(gene name)|psi-mi:BFA1(display_short)|uniprotkb:YJR053W(locus name)|uniprotkb:J1667(orf name)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132161|imex:IM-20214-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	sgd:S000003814|refseq:NP_012587.3|dip:DIP-4825N|mint:P47113|ensemblfungi:YJR053W(gene)|ensemblfungi:YJR053W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR034586	-	-	crc64:1EA75D26FCF041DA	figure legend:Fig 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	rogid:+J/c8Kt9mA/BgFlxHwBvNKuor5U559292	intact-crc:3D3221D035002D5E|rigid:Yt9zEBqed80WyNk5giyWZ7NJxWg	false	glutathione s tranferase tag:n-n	maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P26448	uniprotkb:P38785	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132171|imex:IM-20214-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Fig 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	intact-crc:50AA9EB54085983D|rigid:KQE0C6xKBzUa0BRPX4FbyBbvMnk	false	maltose binding protein tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38987	uniprotkb:P38785	intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C	intact:EBI-7575|uniprotkb:D3DL10|ensemblfungi:YHR061C	psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short)	psi-mi:gic1_yeast(display_long)|uniprotkb:YHR061C(locus name)|uniprotkb:GIC1(gene name)|psi-mi:GIC1(display_short)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132182|imex:IM-20214-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987	refseq:NP_011928.1|sgd:S000001103|mint:P38785|dip:DIP-1217N|ensemblfungi:YHR061C(gene)|ensemblfungi:YHR061C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR000095(PAK-box/P21-Rho-binding)	-	crc64:F650C8946A03707C	-	figure legend:Fig 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292	rogid:y2lnXpqRRXqJrVkJnFjL9wRqp5E559292	intact-crc:FD230EE10824D1EA|rigid:K6CP3pCm2zC2Ec9ExJU0YeUIaF4	false	maltose binding protein tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38987	uniprotkb:P26448	intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132195|imex:IM-20214-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	-	crc64:F650C8946A03707C	crc64:A1DDBFB548E81EA3	figure legend:Fig 4A, 4G|inhibition:Interaction is inhibited by GST-GIC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:13F58915642FDABF|rigid:fdhRdnk2fX8ottOjfCaJgZQMJSo	false	his tag:n-n	maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38987	uniprotkb:P47113	intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C	intact:EBI-3586|uniprotkb:D6VWM4|ensemblfungi:YJR053W	psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short)	psi-mi:bfa1_yeast(display_long)|uniprotkb:Cell cycle arrest protein BFA1(gene name synonym)|uniprotkb:BFA1(gene name)|psi-mi:BFA1(display_short)|uniprotkb:YJR053W(locus name)|uniprotkb:J1667(orf name)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132212|imex:IM-20214-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987	sgd:S000003814|refseq:NP_012587.3|dip:DIP-4825N|mint:P47113|ensemblfungi:YJR053W(gene)|ensemblfungi:YJR053W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR034586	-	crc64:F650C8946A03707C	crc64:1EA75D26FCF041DA	figure legend:Fig 4B|inhibition:Interaction is inhibited by GST-GIC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292	rogid:+J/c8Kt9mA/BgFlxHwBvNKuor5U559292	intact-crc:3CF45C0003B7C946|rigid:A9mYnsAZ0hUDsHG7wBx/QY+tEE8	false	his tag:n-n	maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P26448	uniprotkb:P47113	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-3586|uniprotkb:D6VWM4|ensemblfungi:YJR053W	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:bfa1_yeast(display_long)|uniprotkb:Cell cycle arrest protein BFA1(gene name synonym)|uniprotkb:BFA1(gene name)|psi-mi:BFA1(display_short)|uniprotkb:YJR053W(locus name)|uniprotkb:J1667(orf name)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132227|imex:IM-20214-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	sgd:S000003814|refseq:NP_012587.3|dip:DIP-4825N|mint:P47113|ensemblfungi:YJR053W(gene)|ensemblfungi:YJR053W_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051301"(cell division)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR034586	-	crc64:A1DDBFB548E81EA3	crc64:1EA75D26FCF041DA	figure legend:Fig 4C|inhibition:Interaction is inhibited by GST-GIC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:+J/c8Kt9mA/BgFlxHwBvNKuor5U559292	intact-crc:BC078E5D777B833F|rigid:um4Pb8wb2htWVOHapGH0/+sIe3c	false	glutathione s tranferase tag:n-n	maltose binding protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00684	uniprotkb:P47035	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132298|imex:IM-20214-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	crc64:4EB3985DFA3FD823	crc64:80EDF9A8065EB5A2	figure legend:Fig S1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/05	2014/10/16	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:D1706E0580111522|rigid:pfc6F7X5GhV4Htgws7vy7cnj5ug	false	maltose binding protein tag:n-n	sufficient binding region:1-600|his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38987	uniprotkb:P26448	intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hofken et al. (2004)	pubmed:14734533|imex:IM-20214	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2132253|imex:IM-20214-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	-	crc64:F650C8946A03707C	crc64:A1DDBFB548E81EA3	figure legend:Fig 4D|inhibition:Interaction is inhibited by GIC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/05	2014/10/16	rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:0A33FECCB72DE53C|rigid:fdhRdnk2fX8ottOjfCaJgZQMJSo	false	myc tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)