#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O95278	uniprotkb:O95278	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506722|imex:IM-20410-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/04	2014/10/16	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:F5CFE41317CE7ACE|rigid:B9or3fX0aQhfn5UWTB6udjwFhXI	false	sufficient binding region:129..129-331	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UQK1	uniprotkb:O95278	intact:EBI-2506727|ensembl:ENSP00000238994|uniprotkb:B2R7X0|uniprotkb:O95686	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:ppr3c_human(display_long)|uniprotkb:PPP1R3C(gene name)|psi-mi:PPP1R3C(display_short)|uniprotkb:PPP1R5(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 5(gene name synonym)|uniprotkb:Protein targeting to glycogen(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506742|imex:IM-20410-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119938(gene)|ensembl:ENST00000238994(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030683|interpro:IPR038175|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_005389.1	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/04	2014/10/16	rogid:CuAZTVcnibazQLOIaTqnP0qTqY49606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:CAF14D16195D50B2|rigid:p0LhnnaHpRwZ1kbYhh8mB7MKSVA	false	sufficient binding region:48-317	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UQK1	uniprotkb:O95278	intact:EBI-2506727|ensembl:ENSP00000238994|uniprotkb:B2R7X0|uniprotkb:O95686	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:ppr3c_human(display_long)|uniprotkb:PPP1R3C(gene name)|psi-mi:PPP1R3C(display_short)|uniprotkb:PPP1R5(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 5(gene name synonym)|uniprotkb:Protein targeting to glycogen(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506903|imex:IM-20410-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119938(gene)|ensembl:ENST00000238994(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030683|interpro:IPR038175|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_005389.1	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	-	-	-	figure legend:Fig. 3A, 3C|caution:Q9UQK1 - sequence refered to in the paper appears to have been subsequently withdrawn, so coordinates have been remapped to current UniProtKB sequence.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/04	2014/10/16	rogid:CuAZTVcnibazQLOIaTqnP0qTqY49606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:DF64857585F83E5F|rigid:p0LhnnaHpRwZ1kbYhh8mB7MKSVA	false	sufficient binding region:141-263(IPR005036)|mutation disrupting interaction:247-247,250-250|mutation:85-85,87-87	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95278	uniprotkb:Q9UQK1	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	intact:EBI-2506727|ensembl:ENSP00000238994|uniprotkb:B2R7X0|uniprotkb:O95686	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:ppr3c_human(display_long)|uniprotkb:PPP1R3C(gene name)|psi-mi:PPP1R3C(display_short)|uniprotkb:PPP1R5(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 5(gene name synonym)|uniprotkb:Protein targeting to glycogen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507079|imex:IM-20410-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	ensembl:ENSG00000119938(gene)|ensembl:ENST00000238994(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030683|interpro:IPR038175|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_005389.1	omim:254780(see-also)	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/04	2015/02/05	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	rogid:CuAZTVcnibazQLOIaTqnP0qTqY49606	intact-crc:1C095859C734ABF3|rigid:p0LhnnaHpRwZ1kbYhh8mB7MKSVA	false	mutation disrupting interaction:32-32|mutation disrupting interaction:84-84|mutation disrupting interaction:108-108|mutation disrupting interaction:194-194|mutation decreasing interaction:240-240|mutation decreasing interaction:279-279|mutation disrupting interaction:293-293|mutation disrupting interaction:294-294|mutation disrupting interaction:301-301|mutation increasing interaction:266-266	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95278	uniprotkb:O95278	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507106|imex:IM-20410-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	omim:254780(see-also)	-	-	figure legend:Fig. 5A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/12/04	2015/02/05	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:5C235212743F0184|rigid:B9or3fX0aQhfn5UWTB6udjwFhXI	false	mutation decreasing interaction:293-293|mutation decreasing interaction:301-301|mutation decreasing interaction:108-108|mutation disrupting interaction:194-194	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UQK1	uniprotkb:O95278	intact:EBI-2506727|ensembl:ENSP00000238994|uniprotkb:B2R7X0|uniprotkb:O95686	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:ppr3c_human(display_long)|uniprotkb:PPP1R3C(gene name)|psi-mi:PPP1R3C(display_short)|uniprotkb:PPP1R5(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 5(gene name synonym)|uniprotkb:Protein targeting to glycogen(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2506828|imex:IM-20410-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119938(gene)|ensembl:ENST00000238994(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030683|interpro:IPR038175|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_005389.1	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/04	2014/10/16	rogid:CuAZTVcnibazQLOIaTqnP0qTqY49606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:5AA5256F72476399|rigid:p0LhnnaHpRwZ1kbYhh8mB7MKSVA	false	sufficient binding region:141-263(IPR005036)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95278	uniprotkb:Q9UQK1	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	intact:EBI-2506727|ensembl:ENSP00000238994|uniprotkb:B2R7X0|uniprotkb:O95686	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:ppr3c_human(display_long)|uniprotkb:PPP1R3C(gene name)|psi-mi:PPP1R3C(display_short)|uniprotkb:PPP1R5(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 5(gene name synonym)|uniprotkb:Protein targeting to glycogen(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507033|imex:IM-20410-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	ensembl:ENSG00000119938(gene)|ensembl:ENST00000238994(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030683|interpro:IPR038175|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_005389.1	go:"GO:0044444"(obsolete cytoplasmic part)	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2009/12/04	2014/10/16	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	rogid:CuAZTVcnibazQLOIaTqnP0qTqY49606	intact-crc:E3D997D562B06509|rigid:p0LhnnaHpRwZ1kbYhh8mB7MKSVA	false	-	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P13807	uniprotkb:O95278	intact:EBI-740553|intact:EBI-963094|intact:EBI-2948518|uniprotkb:Q9BTT9|ensembl:ENSP00000317904	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:gys1_human(display_long)|uniprotkb:GYS1(gene name)|psi-mi:GYS1(display_short)|uniprotkb:GYS(gene name synonym)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0051"(fluorescence technology)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507048|imex:IM-20410-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155059.1|refseq:NP_002094.2|ensembl:ENSG00000104812(gene)|ensembl:ENST00000323798(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0007507"(heart development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0061547"(glycogen synthase activity, transferring glucose-1-phosphate)|interpro:IPR008631(Glycogen synthase)|mint:P13807|reactome:R-HSA-3322077|reactome:R-HSA-3785653|reactome:R-HSA-3814836|reactome:R-HSA-3828062	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	go:"GO:0042587"(glycogen granule)|go:"GO:0016529"(sarcoplasmic reticulum)	-	-	figure legend:Fig. 4C, D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2009/12/04	2014/10/16	rogid:qJ6wzje5P3wnfVq0oaFQqhAIQ1Q9606	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:74C1930D4DE87A48|rigid:Yw4n8MjjkV5n21BVdf+befaEZhc	false	enhanced green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
chebi:"CHEBI:28087"	uniprotkb:O95278	intact:EBI-2507162	intact:EBI-2506661|uniprotkb:O95483|uniprotkb:Q5T3F5|uniprotkb:Q8IU96|uniprotkb:Q8IX24|uniprotkb:Q8IX25|uniprotkb:Q9BS66|uniprotkb:Q9UEN2|ensembl:ENSP00000356489|uniprotkb:B3KMU5|uniprotkb:B4DRZ2|uniprotkb:Q6IS15	psi-mi:glycogen(display_short)|psi-mi:"CHEBI:28087"(display_long)	psi-mi:epm2a_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glycogen phosphatase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Fernandez-Sanchez et al. (2003)	pubmed:14532330|imex:IM-20410	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2507138|imex:IM-20410-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011534418.1|ensembl:ENSG00000112425(gene)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|ensembl:ENST00000367519(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|rcsb pdb:4R30|rcsb pdb:4RKK|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_001018051.1|refseq:NP_005661.1|refseq:XP_006715627.1|refseq:XP_016866789.1|refseq:XP_016866790.1|refseq:XP_016866791.1	-	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/12/04	2014/10/16	-	rogid:SzLH6Z+48utiGISu59PgvgBzXD49606	intact-crc:99663F8E80793E63	false	-	mutation disrupting interaction:32-32|mutation disrupting interaction:108-108|mutation disrupting interaction:279-279|mutation disrupting interaction:293-293|mutation disrupting interaction:294-294|mutation disrupting interaction:301-301	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)