#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q95NU8 uniprotkb:Q7KJ08 intact:EBI-104595|uniprotkb:Q9V657|ensemblmetazoa:FBpp0087128|ensemblmetazoa:FBpp0305279 intact:EBI-2320938|ensemblmetazoa:FBpp0086264|ensemblmetazoa:FBpp0304259 psi-mi:q95nu8_drome(display_long)|uniprotkb:jeb(gene name)|psi-mi:jeb(display_short)|uniprotkb:CG13180(gene name synonym)|uniprotkb:CG13182(gene name synonym)|uniprotkb:Dmel\CG30040(gene name synonym)|uniprotkb:Jeb(gene name synonym)|uniprotkb:"l(2)SH0422"(gene name synonym)|uniprotkb:"l(2)k05644"(gene name synonym)|uniprotkb:CG30040(orf name)|uniprotkb:Dmel_CG30040(orf name) psi-mi:q7kj08_drome(display_long)|uniprotkb:Alk(gene name)|psi-mi:Alk(display_short)|uniprotkb:ALK(gene name synonym)|uniprotkb:DAlk(gene name synonym)|uniprotkb:DAlk53(gene name synonym)|uniprotkb:Dmel\CG8250(gene name synonym)|uniprotkb:alk(gene name synonym)|uniprotkb:dALK(gene name synonym)|uniprotkb:dAlk(gene name synonym)|uniprotkb:mili(gene name synonym)|uniprotkb:CG8250(orf name)|uniprotkb:Dmel_CG8250(orf name) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2003) pubmed:14523446|imex:IM-20299 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320965|imex:IM-20299-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610726.1|flybase:FBgn0086677|refseq:NP_001260910.1|ensemblmetazoa:FBgn0086677(gene)|ensemblmetazoa:FBtr0088021(transcript)|ensemblmetazoa:FBtr0333065(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0007522"(visceral muscle development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043195"(terminal bouton)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR036055|go:"GO:0005576"(extracellular region) refseq:NP_652600.1|flybase:FBgn0040505|refseq:NP_001261027.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR000998(MAM)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|ensemblmetazoa:FBgn0040505(gene)|ensemblmetazoa:FBtr0087118(transcript)|ensemblmetazoa:FBtr0331926(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0048565"(digestive tract development)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission) - - - figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2009/05/05 2014/10/16 rogid:SlCRLmYpfW1RO2i0y95yS6bwzIQ7227 rogid:gA9rBsORmRKz3pxRxXK4e5HA4687227 intact-crc:0141C5EBFB18F6DB|rigid:Zex1TZ2F06cJjiXy7oLq7pQpLlo false tag:?-? sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7KJ08 uniprotkb:Q95NU8 intact:EBI-2320938|ensemblmetazoa:FBpp0086264|ensemblmetazoa:FBpp0304259 intact:EBI-104595|uniprotkb:Q9V657|ensemblmetazoa:FBpp0087128|ensemblmetazoa:FBpp0305279 psi-mi:q7kj08_drome(display_long)|uniprotkb:Alk(gene name)|psi-mi:Alk(display_short)|uniprotkb:ALK(gene name synonym)|uniprotkb:DAlk(gene name synonym)|uniprotkb:DAlk53(gene name synonym)|uniprotkb:Dmel\CG8250(gene name synonym)|uniprotkb:alk(gene name synonym)|uniprotkb:dALK(gene name synonym)|uniprotkb:dAlk(gene name synonym)|uniprotkb:mili(gene name synonym)|uniprotkb:CG8250(orf name)|uniprotkb:Dmel_CG8250(orf name) psi-mi:q95nu8_drome(display_long)|uniprotkb:jeb(gene name)|psi-mi:jeb(display_short)|uniprotkb:CG13180(gene name synonym)|uniprotkb:CG13182(gene name synonym)|uniprotkb:Dmel\CG30040(gene name synonym)|uniprotkb:Jeb(gene name synonym)|uniprotkb:"l(2)SH0422"(gene name synonym)|uniprotkb:"l(2)k05644"(gene name synonym)|uniprotkb:CG30040(orf name)|uniprotkb:Dmel_CG30040(orf name) psi-mi:"MI:0049"(filter binding) Lee et al. (2003) pubmed:14523446|imex:IM-20299 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2320986|imex:IM-20299-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_652600.1|flybase:FBgn0040505|refseq:NP_001261027.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR000998(MAM)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|ensemblmetazoa:FBgn0040505(gene)|ensemblmetazoa:FBtr0087118(transcript)|ensemblmetazoa:FBtr0331926(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0048565"(digestive tract development)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071212"(subsynaptic reticulum)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission) refseq:NP_610726.1|flybase:FBgn0086677|refseq:NP_001260910.1|ensemblmetazoa:FBgn0086677(gene)|ensemblmetazoa:FBtr0088021(transcript)|ensemblmetazoa:FBtr0333065(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0007522"(visceral muscle development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0042051"(compound eye photoreceptor development)|go:"GO:0042694"(muscle cell fate specification)|go:"GO:0043195"(terminal bouton)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0061176"(type Ib terminal bouton)|go:"GO:0061177"(type Is terminal bouton)|go:"GO:1900074"(negative regulation of neuromuscular synaptic transmission)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR036055|go:"GO:0005576"(extracellular region) - - - figure legend:4b, 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/05/05 2014/10/16 rogid:gA9rBsORmRKz3pxRxXK4e5HA4687227 rogid:SlCRLmYpfW1RO2i0y95yS6bwzIQ7227 intact-crc:E67CDD36864ABFCD|rigid:Zex1TZ2F06cJjiXy7oLq7pQpLlo false - tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)