#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:15422"	uniprotkb:Q05931	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-35227|uniprotkb:D6VZ06|ensemblfungi:YLR369W	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hsp7q_yeast(display_long)|uniprotkb:SSQ1(gene name)|psi-mi:SSQ1(display_short)|uniprotkb:mtHSP70 homolog(gene name synonym)|uniprotkb:SSC2(gene name synonym)|uniprotkb:Stress-seventy subfamily Q protein 1(gene name synonym)|uniprotkb:YLR369W(locus name)|uniprotkb:Heat shock protein SSQ1, mitochondrial(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215660|imex:IM-20250-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_013473.1|sgd:S000004361|mint:Q05931|dip:DIP-6407N|ensemblfungi:YLR369W(gene)|ensemblfungi:YLR369W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	crc64:AC2DF42F3D623892	figure legend:Figs. 1, 4, 5C, 5D, 6, 7|comment:ATP is 32P-tagged|stimulant:"Jac1 (P53193) at a 50-fold excess"|stimulant:"Jac1 (P53193) and Isu1 (Q03020) at stoichiometric concentrations, further enhanced by the addition of Mge1."|comment:ATPase activity is not inhibited by unlabelled ATP indicating that nucleotide is tightly bound to protein|inhibition:Mge1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	-	rogid:PGcPon176Ea5v+lmsUYk5y4yaZU559292	intact-crc:15F430AF4C79EF33	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P0A6Z1	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-546238|uniprotkb:P36541|uniprotkb:P76990|uniprotkb:P77497|ensemblbacteria:AAC75579|ensemblbacteria:BAA16420	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hsca_ecoli(display_long)|uniprotkb:hscA(gene name)|psi-mi:hscA(display_short)|uniprotkb:hsc(gene name synonym)|uniprotkb:b2526(locus name)|uniprotkb:Hsc66(gene name synonym)|uniprotkb:JW2510(locus name)	psi-mi:"MI:0880"(atpase assay)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215745|imex:IM-20250-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC75579(transcript)|ensemblbacteria:b2526(gene)|ensemblbacteria:BAA16420(gene)|ensemblbacteria:BAA16420(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0043531"(ADP binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1990230"(iron-sulfur cluster transfer complex)|interpro:IPR010236(ISC system FeS cluster assembly, HscA chaperone)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042039|interpro:IPR043129|refseq:NP_417021.1|rcsb pdb:1U00|refseq:WP_001196613.1|dip:DIP-47348N	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	crc64:9C80E6EF1BFDAB48	figure legend:Fig. 4|comment:ATP is 32P-tagged|inhibition:Unlabelled ATP|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	-	rogid:JwYlfB8R+xSUlGgjas85aY/PQNY83333	intact-crc:90D87F544336704C	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53193	uniprotkb:Q03020	intact:EBI-23714|uniprotkb:D6VUB9|ensemblfungi:YGL018C	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:jac1_yeast(display_long)|uniprotkb:YGL018C(locus name)|uniprotkb:JAC1(gene name)|psi-mi:JAC1(display_short)|uniprotkb:SEO2(gene name synonym)|uniprotkb:J-type accessory chaperone 1(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215679|imex:IM-20250-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011497.1|sgd:S000002986|dip:DIP-5603N|reactome:R-SCE-1362409|reactome:R-SCE-1268020|ensemblfungi:YGL018C(gene)|ensemblfungi:YGL018C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|interpro:IPR036386|interpro:IPR036869|rcsb pdb:3UO2|rcsb pdb:3UO3	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	-	-	crc64:E240845A27D2E9EE	sample process:Using purified SPR for this purpose, Jac1 was passed over the surface of a sensor chip to which purified Isu1 was immobilized by random cross-linking.|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:0zP3ejO42N4UHAeb4wLKtjdC5V4559292	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:0E1291804B708B99|rigid:f0dBKozuEeHq0il9gbRUjKtNbts	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:Q05931	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-35227|uniprotkb:D6VZ06|ensemblfungi:YLR369W	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:hsp7q_yeast(display_long)|uniprotkb:SSQ1(gene name)|psi-mi:SSQ1(display_short)|uniprotkb:mtHSP70 homolog(gene name synonym)|uniprotkb:SSC2(gene name synonym)|uniprotkb:Stress-seventy subfamily Q protein 1(gene name synonym)|uniprotkb:YLR369W(locus name)|uniprotkb:Heat shock protein SSQ1, mitochondrial(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215688|imex:IM-20250-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_013473.1|sgd:S000004361|mint:Q05931|dip:DIP-6407N|ensemblfungi:YLR369W(gene)|ensemblfungi:YLR369W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)	-	crc64:E240845A27D2E9EE	crc64:AC2DF42F3D623892	figure legend:Fig. 2B|comment:Weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:PGcPon176Ea5v+lmsUYk5y4yaZU559292	intact-crc:0A22B9D569607277|rigid:/Xt7jLKpRglePbXMmlnF87PJsM4	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:Q05931	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-35227|uniprotkb:D6VZ06|ensemblfungi:YLR369W	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:hsp7q_yeast(display_long)|uniprotkb:SSQ1(gene name)|psi-mi:SSQ1(display_short)|uniprotkb:mtHSP70 homolog(gene name synonym)|uniprotkb:SSC2(gene name synonym)|uniprotkb:Stress-seventy subfamily Q protein 1(gene name synonym)|uniprotkb:YLR369W(locus name)|uniprotkb:Heat shock protein SSQ1, mitochondrial(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215703|imex:IM-20250-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_013473.1|sgd:S000004361|mint:Q05931|dip:DIP-6407N|ensemblfungi:YLR369W(gene)|ensemblfungi:YLR369W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)	-	crc64:E240845A27D2E9EE	crc64:AC2DF42F3D623892	figure legend:Fig. 2B|comment:ssq1 and jac1 added to the chip at concentrations where individual protein binding to isu1 is negligible but increases when added in concert.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:PGcPon176Ea5v+lmsUYk5y4yaZU559292	intact-crc:186807FE4F74EB42|rigid:E5tl5UfIrpZYZg6U9ErMtN5fJS0	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:P53193	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-23714|uniprotkb:D6VUB9|ensemblfungi:YGL018C	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:jac1_yeast(display_long)|uniprotkb:YGL018C(locus name)|uniprotkb:JAC1(gene name)|psi-mi:JAC1(display_short)|uniprotkb:SEO2(gene name synonym)|uniprotkb:J-type accessory chaperone 1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215703|imex:IM-20250-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_011497.1|sgd:S000002986|dip:DIP-5603N|reactome:R-SCE-1362409|reactome:R-SCE-1268020|ensemblfungi:YGL018C(gene)|ensemblfungi:YGL018C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|interpro:IPR036386|interpro:IPR036869|rcsb pdb:3UO2|rcsb pdb:3UO3	-	crc64:E240845A27D2E9EE	-	figure legend:Fig. 2B|comment:ssq1 and jac1 added to the chip at concentrations where individual protein binding to isu1 is negligible but increases when added in concert.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:0zP3ejO42N4UHAeb4wLKtjdC5V4559292	intact-crc:186807FE4F74EB42|rigid:E5tl5UfIrpZYZg6U9ErMtN5fJS0	false	his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05931	uniprotkb:P38523	intact:EBI-35227|uniprotkb:D6VZ06|ensemblfungi:YLR369W	intact:EBI-7891|uniprotkb:D6W2T6|ensemblfungi:YOR232W	psi-mi:hsp7q_yeast(display_long)|uniprotkb:SSQ1(gene name)|psi-mi:SSQ1(display_short)|uniprotkb:mtHSP70 homolog(gene name synonym)|uniprotkb:SSC2(gene name synonym)|uniprotkb:Stress-seventy subfamily Q protein 1(gene name synonym)|uniprotkb:YLR369W(locus name)|uniprotkb:Heat shock protein SSQ1, mitochondrial(gene name synonym)	psi-mi:grpe_yeast(display_long)|uniprotkb:MGE1(gene name)|psi-mi:MGE1(display_short)|uniprotkb:GRPE(gene name synonym)|uniprotkb:GRPE1(gene name synonym)|uniprotkb:YGE1(gene name synonym)|uniprotkb:YOR232W(locus name)|uniprotkb:O5099(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215754|imex:IM-20250-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013473.1|sgd:S000004361|mint:Q05931|dip:DIP-6407N|ensemblfungi:YLR369W(gene)|ensemblfungi:YLR369W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)	sgd:S000005758|refseq:NP_014875.3|dip:DIP-775N|ensemblfungi:YOR232W(gene)|ensemblfungi:YOR232W_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042026"(protein refolding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)	-	crc64:AC2DF42F3D623892	crc64:816A5E26C648E613	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:PGcPon176Ea5v+lmsUYk5y4yaZU559292	rogid:wkvU4fHqvggWswkIDrsEDkEF2YA559292	intact-crc:CDE5D374B214628F|rigid:Q47hfGWIRwD5K4d34z9cvB4n1QY	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:Q05931	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-35227|uniprotkb:D6VZ06|ensemblfungi:YLR369W	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:hsp7q_yeast(display_long)|uniprotkb:SSQ1(gene name)|psi-mi:SSQ1(display_short)|uniprotkb:mtHSP70 homolog(gene name synonym)|uniprotkb:SSC2(gene name synonym)|uniprotkb:Stress-seventy subfamily Q protein 1(gene name synonym)|uniprotkb:YLR369W(locus name)|uniprotkb:Heat shock protein SSQ1, mitochondrial(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215721|imex:IM-20250-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_013473.1|sgd:S000004361|mint:Q05931|dip:DIP-6407N|ensemblfungi:YLR369W(gene)|ensemblfungi:YLR369W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)	-	crc64:E240845A27D2E9EE	crc64:AC2DF42F3D623892	figure legend:Fig. 3D|comment:Complex only forms in absence of Calcium|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:PGcPon176Ea5v+lmsUYk5y4yaZU559292	intact-crc:536412A0444CE01E|rigid:/Xt7jLKpRglePbXMmlnF87PJsM4	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P53193	uniprotkb:Q03020	intact:EBI-23714|uniprotkb:D6VUB9|ensemblfungi:YGL018C	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:jac1_yeast(display_long)|uniprotkb:YGL018C(locus name)|uniprotkb:JAC1(gene name)|psi-mi:JAC1(display_short)|uniprotkb:SEO2(gene name synonym)|uniprotkb:J-type accessory chaperone 1(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Dutkiewicz et al. (2003)	pubmed:12756240|imex:IM-20250	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2215734|imex:IM-20250-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011497.1|sgd:S000002986|dip:DIP-5603N|reactome:R-SCE-1362409|reactome:R-SCE-1268020|ensemblfungi:YGL018C(gene)|ensemblfungi:YGL018C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|interpro:IPR036386|interpro:IPR036869|rcsb pdb:3UO2|rcsb pdb:3UO3	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	-	-	crc64:E240845A27D2E9EE	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/02/05	2014/10/16	rogid:0zP3ejO42N4UHAeb4wLKtjdC5V4559292	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:799A4425D0996D6B|rigid:f0dBKozuEeHq0il9gbRUjKtNbts	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)