#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95257 uniprotkb:Q8TAE8 intact:EBI-448202|intact:EBI-5773903|uniprotkb:Q9C076|uniprotkb:Q5VZ87|ensembl:ENSP00000252506 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45g_human(display_long)|uniprotkb:DDIT2(gene name synonym)|uniprotkb:Cytokine-responsive protein CR6(gene name synonym)|uniprotkb:DNA damage-inducible transcript 2 protein(gene name synonym)|uniprotkb:GADD45G(gene name)|psi-mi:GADD45G(display_short)|uniprotkb:CR6(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2266820|imex:IM-19358-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006696.1|dip:DIP-24218N|ensembl:ENSG00000130222(gene)|ensembl:ENST00000252506(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2WAL|rcsb pdb:3FFM refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/27 2014/10/16 rogid:/0gLr1aWX5yOU3Ytc4/IZn700IQ9606 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:54B640435CED8417|rigid:4OewzapTS08Pz9YwVwu5R/UP3JY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95257 uniprotkb:Q8TAE8 intact:EBI-448202|intact:EBI-5773903|uniprotkb:Q9C076|uniprotkb:Q5VZ87|ensembl:ENSP00000252506 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45g_human(display_long)|uniprotkb:DDIT2(gene name synonym)|uniprotkb:Cytokine-responsive protein CR6(gene name synonym)|uniprotkb:DNA damage-inducible transcript 2 protein(gene name synonym)|uniprotkb:GADD45G(gene name)|psi-mi:GADD45G(display_short)|uniprotkb:CR6(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0096"(pull down) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2266830|imex:IM-19358-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006696.1|dip:DIP-24218N|ensembl:ENSG00000130222(gene)|ensembl:ENST00000252506(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2WAL|rcsb pdb:3FFM refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/27 2014/10/16 rogid:/0gLr1aWX5yOU3Ytc4/IZn700IQ9606 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:8E812131105CD9D5|rigid:4OewzapTS08Pz9YwVwu5R/UP3JY false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8TAE8 uniprotkb:P24522 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:"MI:0096"(pull down) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2266886|imex:IM-19358-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) - - - figure legend:Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/27 2014/10/16 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 intact-crc:13EEB3381394490E|rigid:MfGBdTwivT4hemI+V1zhq6vqgmI false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P22339 uniprotkb:Q8TAE8 intact:EBI-2266938|uniprotkb:Q3U342|uniprotkb:Q9R106|ensembl:ENSMUSP00000015456 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45b_mouse(display_long)|uniprotkb:Gadd45b(gene name)|psi-mi:Gadd45b(display_short)|uniprotkb:Myd118(gene name synonym)|uniprotkb:Myeloid differentiation primary response protein MyD118(gene name synonym)|uniprotkb:Negative growth regulatory protein MyD118(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0096"(pull down) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2266958|imex:IM-19358-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032681.1|ensembl:ENSMUSG00000015312(gene)|ensembl:ENSMUST00000015456(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064 refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/27 2014/10/16 rogid:V6lVAUQi7jMqNPY9wYQlUTDhrjk10090 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:A2ACC9E6A0FB81E3|rigid:5lgtb0NZNv9dHDCb3BLJLbyGkTE false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P24522 uniprotkb:Q8TAE8 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2266976|imex:IM-19358-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2009/02/27 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:066553B8AA23C7A0|rigid:MfGBdTwivT4hemI+V1zhq6vqgmI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22339 uniprotkb:Q8TAE8 intact:EBI-2266938|uniprotkb:Q3U342|uniprotkb:Q9R106|ensembl:ENSMUSP00000015456 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45b_mouse(display_long)|uniprotkb:Gadd45b(gene name)|psi-mi:Gadd45b(display_short)|uniprotkb:Myd118(gene name synonym)|uniprotkb:Myeloid differentiation primary response protein MyD118(gene name synonym)|uniprotkb:Negative growth regulatory protein MyD118(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2266981|imex:IM-19358-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032681.1|ensembl:ENSMUSG00000015312(gene)|ensembl:ENSMUST00000015456(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064 refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2009/02/27 2014/10/16 rogid:V6lVAUQi7jMqNPY9wYQlUTDhrjk10090 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:4BB94C80EF67C368|rigid:5lgtb0NZNv9dHDCb3BLJLbyGkTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAE8 uniprotkb:O95257 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 intact:EBI-448202|intact:EBI-5773903|uniprotkb:Q9C076|uniprotkb:Q5VZ87|ensembl:ENSP00000252506 psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:ga45g_human(display_long)|uniprotkb:DDIT2(gene name synonym)|uniprotkb:Cytokine-responsive protein CR6(gene name synonym)|uniprotkb:DNA damage-inducible transcript 2 protein(gene name synonym)|uniprotkb:GADD45G(gene name)|psi-mi:GADD45G(display_short)|uniprotkb:CR6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2266986|imex:IM-19358-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 refseq:NP_006696.1|dip:DIP-24218N|ensembl:ENSG00000130222(gene)|ensembl:ENST00000252506(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2WAL|rcsb pdb:3FFM - - - figure legend:Fig. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2009/02/27 2014/10/16 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 rogid:/0gLr1aWX5yOU3Ytc4/IZn700IQ9606 intact-crc:4AC05F936067A978|rigid:4OewzapTS08Pz9YwVwu5R/UP3JY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TAE8 uniprotkb:P22339 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 intact:EBI-2266938|uniprotkb:Q3U342|uniprotkb:Q9R106|ensembl:ENSMUSP00000015456 psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:ga45b_mouse(display_long)|uniprotkb:Gadd45b(gene name)|psi-mi:Gadd45b(display_short)|uniprotkb:Myd118(gene name synonym)|uniprotkb:Myeloid differentiation primary response protein MyD118(gene name synonym)|uniprotkb:Negative growth regulatory protein MyD118(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267001|imex:IM-19358-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 refseq:NP_032681.1|ensembl:ENSMUSG00000015312(gene)|ensembl:ENSMUST00000015456(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064 - - - figure legend:Fig. 3D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 rogid:V6lVAUQi7jMqNPY9wYQlUTDhrjk10090 intact-crc:ECE052F88925A750|rigid:5lgtb0NZNv9dHDCb3BLJLbyGkTE false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P24522 uniprotkb:Q8TAE8 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267010|imex:IM-19358-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:9FCA1E368A86C4DA|rigid:MfGBdTwivT4hemI+V1zhq6vqgmI false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95257 uniprotkb:Q8TAE8 intact:EBI-448202|intact:EBI-5773903|uniprotkb:Q9C076|uniprotkb:Q5VZ87|ensembl:ENSP00000252506 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:ga45g_human(display_long)|uniprotkb:DDIT2(gene name synonym)|uniprotkb:Cytokine-responsive protein CR6(gene name synonym)|uniprotkb:DNA damage-inducible transcript 2 protein(gene name synonym)|uniprotkb:GADD45G(gene name)|psi-mi:GADD45G(display_short)|uniprotkb:CR6(gene name synonym) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267019|imex:IM-19358-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006696.1|dip:DIP-24218N|ensembl:ENSG00000130222(gene)|ensembl:ENST00000252506(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2WAL|rcsb pdb:3FFM refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Fig. 3E|caution:It is not clear if the GADD45G immunoprecipitated in this experiment is endogenous or transfected human. It has been assumed that this is exogenous.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:/0gLr1aWX5yOU3Ytc4/IZn700IQ9606 rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 intact-crc:921C399B94E5D3D0|rigid:4OewzapTS08Pz9YwVwu5R/UP3JY false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8SPE7 uniprotkb:O95257 intact:EBI-2267139 intact:EBI-448202|intact:EBI-5773903|uniprotkb:Q9C076|uniprotkb:Q5VZ87|ensembl:ENSP00000252506 psi-mi:g45ip_chlae(display_long)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym) psi-mi:ga45g_human(display_long)|uniprotkb:DDIT2(gene name synonym)|uniprotkb:Cytokine-responsive protein CR6(gene name synonym)|uniprotkb:DNA damage-inducible transcript 2 protein(gene name synonym)|uniprotkb:GADD45G(gene name)|psi-mi:GADD45G(display_short)|uniprotkb:CR6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267132|imex:IM-19358-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018472|interpro:IPR043035|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle) refseq:NP_006696.1|dip:DIP-24218N|ensembl:ENSG00000130222(gene)|ensembl:ENST00000252506(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2WAL|rcsb pdb:3FFM - - - figure legend:Fig. 3F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:9DiN5P08HcQ99LMhV+744JT2FGc9534 rogid:/0gLr1aWX5yOU3Ytc4/IZn700IQ9606 intact-crc:54240BC2C401BE22|rigid:PA2Bcii7YT6cgMWZqPe3Ds6osZg false - flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P24522 uniprotkb:Q8SPE7 intact:EBI-448167|uniprotkb:Q5TCA7|uniprotkb:Q5TCA8|ensembl:ENSP00000360025 intact:EBI-2267139 psi-mi:ga45a_human(display_long)|uniprotkb:DNA damage-inducible transcript 1 protein(gene name synonym)|uniprotkb:GADD45A(gene name)|psi-mi:GADD45A(display_short)|uniprotkb:DDIT1(gene name synonym)|uniprotkb:GADD45(gene name synonym) psi-mi:g45ip_chlae(display_long)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267154|imex:IM-19358-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186671.1|refseq:NP_001915.1|refseq:NP_001186670.1|dip:DIP-24217N|ensembl:ENSG00000116717(gene)|ensembl:ENST00000370986(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064|rcsb pdb:2KG4|reactome:R-HSA-6804114|reactome:R-HSA-9617828|go:"GO:0042803"(protein homodimerization activity) interpro:IPR018472|interpro:IPR043035|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle) - - - figure legend:Fig. 3F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:3X3fjZ3b5kaLnfhh5bSDMP4Xu+o9606 rogid:9DiN5P08HcQ99LMhV+744JT2FGc9534 intact-crc:F891CDFC8BE2A090|rigid:G6mM99oaxrLJYnOu4DhglZSba8U false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P22339 uniprotkb:Q8SPE7 intact:EBI-2266938|uniprotkb:Q3U342|uniprotkb:Q9R106|ensembl:ENSMUSP00000015456 intact:EBI-2267139 psi-mi:ga45b_mouse(display_long)|uniprotkb:Gadd45b(gene name)|psi-mi:Gadd45b(display_short)|uniprotkb:Myd118(gene name synonym)|uniprotkb:Myeloid differentiation primary response protein MyD118(gene name synonym)|uniprotkb:Negative growth regulatory protein MyD118(gene name synonym) psi-mi:g45ip_chlae(display_long)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2003) pubmed:12716909|imex:IM-19358|mint:MINT-5216338 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2267161|imex:IM-19358-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032681.1|ensembl:ENSMUSG00000015312(gene)|ensembl:ENSMUST00000015456(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR024824|interpro:IPR029064 interpro:IPR018472|interpro:IPR043035|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle) - - - figure legend:Fig. 3F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2009/02/27 2014/10/16 rogid:V6lVAUQi7jMqNPY9wYQlUTDhrjk10090 rogid:9DiN5P08HcQ99LMhV+744JT2FGc9534 intact-crc:F26087FD2F1CB040|rigid:UxPOxPQr37gzq7Eir1TIB+8Sg94 false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)