#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49702	uniprotkb:P26990	intact:EBI-8631833|intact:UNK-6039729	intact:EBI-8631854|ensembl:ENSGALP00000041604|intact:MINT-6824981	psi-mi:arf5_chick(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short)|uniprotkb:CPS3(gene name synonym)	psi-mi:arf6_chick(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)|uniprotkb:CPS1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631891|mint:MINT-6825952	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|refseq:NP_990656.1|interpro:IPR005225(Small GTP-binding protein)|mint:P49702|mint:MINT-6825956(identity)|uniprotkb:P49702(P49702)	ensembl:ENSGALG00000026944(gene)|ensembl:ENSGALT00000045497(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P26990|interpro:IPR005225(Small GTP-binding protein)|refseq:NP_001075174.1|mint:MINT-6825953(identity)|uniprotkb:P26990(P26990)	-	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint	figure legend:F6|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2009/01/23	2014/10/16	rogid:6OUkkUZ6oQauUVtFo2kyODIfZZM9031	rogid:+aP3jnYLOKdSs77R9xzhe83W+n09031	intact-crc:CDE56DACE9EA6184|rigid:hwgZ2a3PBQhjBOIn8pZc83kmcNE	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P49702	uniprotkb:Q9DG15	intact:EBI-8631833|intact:UNK-6039729	intact:EBI-8612826|intact:MINT-260012|uniprotkb:E1BYJ4	psi-mi:arf5_chick(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short)|uniprotkb:CPS3(gene name synonym)	psi-mi:q9dg15_chick(display_long)	psi-mi:"MI:0416"(fluorescence microscopy)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631891|mint:MINT-6825952	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR027417|interpro:IPR006689(ARF/SAR superfamily)|refseq:NP_990656.1|interpro:IPR005225(Small GTP-binding protein)|mint:P49702|mint:MINT-6825956(identity)|uniprotkb:P49702(P49702)	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|interpro:IPR032352|interpro:IPR020683|interpro:IPR022018|refseq:NP_989627.1|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278|mint:Q9DG15|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|mint:MINT-6825959(identity)|uniprotkb:Q9DG15(Q9DG15)	-	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint	comment:mint	figure legend:F6|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2009/01/23	2014/10/16	rogid:6OUkkUZ6oQauUVtFo2kyODIfZZM9031	rogid:nPWbyHDAbeLHadKv/FLZLtVLShM9031	intact-crc:CDE56DACE9EA6184|rigid:hwgZ2a3PBQhjBOIn8pZc83kmcNE	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9DG15	uniprotkb:P26990	intact:EBI-8612826|intact:MINT-260012|uniprotkb:E1BYJ4	intact:EBI-8631854|ensembl:ENSGALP00000041604|intact:MINT-6824981	psi-mi:q9dg15_chick(display_long)	psi-mi:arf6_chick(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short)|uniprotkb:CPS1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8631907|mint:MINT-6825962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|interpro:IPR032352|interpro:IPR020683|interpro:IPR022018|refseq:NP_989627.1|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278|mint:Q9DG15|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|mint:MINT-6825966(identity)|uniprotkb:Q9DG15(Q9DG15)	ensembl:ENSGALG00000026944(gene)|ensembl:ENSGALT00000045497(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P26990|interpro:IPR005225(Small GTP-binding protein)|refseq:NP_001075174.1|mint:MINT-6825963(identity)|uniprotkb:P26990(P26990)	-	comment:mint	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint	figure legend:F7|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:9031(chick-neuron)|taxid:9031(Chick neuron)	-	2009/01/23	2014/10/16	rogid:nPWbyHDAbeLHadKv/FLZLtVLShM9031	rogid:+aP3jnYLOKdSs77R9xzhe83W+n09031	intact-crc:9BC858E55D0C7EB4|rigid:bs3znSnMYFTQk4rQEWHXtouFKJk	false	binding-associated region:229-740(MINT-6825969)	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q6LC82	uniprotkb:Q9DG15	intact:EBI-8631931|ensembl:ENSGALP00000011538|intact:UNK-5955104|uniprotkb:F1N8D9	intact:EBI-8612826|intact:MINT-260012|uniprotkb:E1BYJ4	psi-mi:q6lc82_chick(display_long)|uniprotkb:cRac1A(gene name)|psi-mi:cRac1A(display_short)|uniprotkb:RAC1(gene name synonym)	psi-mi:q9dg15_chick(display_long)	psi-mi:"MI:0096"(pull down)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8632003|mint:MINT-6825974	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-GGA-3928662|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-4420097|reactome:R-GGA-389359|reactome:R-GGA-445144|reactome:R-GGA-5218920|reactome:R-GGA-5625740|reactome:R-GGA-5625970|reactome:R-GGA-5626467|reactome:R-GGA-5627123|reactome:R-GGA-5663213|reactome:R-GGA-5663220|reactome:R-GGA-5668599|reactome:R-GGA-5687128|reactome:R-GGA-6798695|reactome:R-GGA-6811558|reactome:R-GGA-8849471|reactome:R-GGA-8875555|reactome:R-GGA-9013149|reactome:R-GGA-9032759|reactome:R-GGA-983231|ensembl:ENSGALG00000007130(gene)|ensembl:ENSGALT00000011552(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6LC82|reactome:R-GGA-114604|reactome:R-GGA-1257604|reactome:R-GGA-193648|reactome:R-GGA-2029482|reactome:R-GGA-2424491|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|reactome:R-GGA-2871796|refseq:NP_990348.1|mint:MINT-6825978(identity)|uniprotkb:Q6LC82(Q6LC82)	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|interpro:IPR032352|interpro:IPR020683|interpro:IPR022018|refseq:NP_989627.1|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278|mint:Q9DG15|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|mint:MINT-6825975(identity)|uniprotkb:Q9DG15(Q9DG15)	-	comment:mint	comment:mint	figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9031	rogid:nPWbyHDAbeLHadKv/FLZLtVLShM9031	intact-crc:F654F64728758124|rigid:Dnf8vYdzqghDzURIBMMfdtEA+T4	false	glutathione s tranferase tag:?-?(MINT-6825981)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6LC82	uniprotkb:Q5ZLR6	intact:EBI-8631931|ensembl:ENSGALP00000011538|intact:UNK-5955104|uniprotkb:F1N8D9	intact:EBI-8631977|intact:MINT-6825004	psi-mi:q6lc82_chick(display_long)|uniprotkb:cRac1A(gene name)|psi-mi:cRac1A(display_short)|uniprotkb:RAC1(gene name synonym)	psi-mi:arhg6_chick(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:RCJMB04_5b15(orf name)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8632003|mint:MINT-6825974	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-GGA-3928662|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-4420097|reactome:R-GGA-389359|reactome:R-GGA-445144|reactome:R-GGA-5218920|reactome:R-GGA-5625740|reactome:R-GGA-5625970|reactome:R-GGA-5626467|reactome:R-GGA-5627123|reactome:R-GGA-5663213|reactome:R-GGA-5663220|reactome:R-GGA-5668599|reactome:R-GGA-5687128|reactome:R-GGA-6798695|reactome:R-GGA-6811558|reactome:R-GGA-8849471|reactome:R-GGA-8875555|reactome:R-GGA-9013149|reactome:R-GGA-9032759|reactome:R-GGA-983231|ensembl:ENSGALG00000007130(gene)|ensembl:ENSGALT00000011552(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6LC82|reactome:R-GGA-114604|reactome:R-GGA-1257604|reactome:R-GGA-193648|reactome:R-GGA-2029482|reactome:R-GGA-2424491|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|reactome:R-GGA-2871796|refseq:NP_990348.1|mint:MINT-6825978(identity)|uniprotkb:Q6LC82(Q6LC82)	interpro:IPR032409|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001006432.1|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|mint:Q5ZLR6|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6825983(identity)|uniprotkb:Q5ZLR6(Q5ZLR6)	-	comment:mint	function:"Acts as a RAC1 guanine nucleotide exchange factor (GEF)"|comment:mint	figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9031	rogid:CBL2c9qaCqyB8+OkQNYJEQ5Mktg9031	intact-crc:F654F64728758124|rigid:Dnf8vYdzqghDzURIBMMfdtEA+T4	false	glutathione s tranferase tag:?-?(MINT-6825981)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6LC82	uniprotkb:P49024	intact:EBI-8631931|ensembl:ENSGALP00000011538|intact:UNK-5955104|uniprotkb:F1N8D9	intact:EBI-2896280	psi-mi:q6lc82_chick(display_long)|uniprotkb:cRac1A(gene name)|psi-mi:cRac1A(display_short)|uniprotkb:RAC1(gene name synonym)	psi-mi:paxi_chick(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short)	psi-mi:"MI:0096"(pull down)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8632003|mint:MINT-6825974	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-GGA-3928662|reactome:R-GGA-3928664|reactome:R-GGA-3928665|reactome:R-GGA-4420097|reactome:R-GGA-389359|reactome:R-GGA-445144|reactome:R-GGA-5218920|reactome:R-GGA-5625740|reactome:R-GGA-5625970|reactome:R-GGA-5626467|reactome:R-GGA-5627123|reactome:R-GGA-5663213|reactome:R-GGA-5663220|reactome:R-GGA-5668599|reactome:R-GGA-5687128|reactome:R-GGA-6798695|reactome:R-GGA-6811558|reactome:R-GGA-8849471|reactome:R-GGA-8875555|reactome:R-GGA-9013149|reactome:R-GGA-9032759|reactome:R-GGA-983231|ensembl:ENSGALG00000007130(gene)|ensembl:ENSGALT00000011552(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6LC82|reactome:R-GGA-114604|reactome:R-GGA-1257604|reactome:R-GGA-193648|reactome:R-GGA-2029482|reactome:R-GGA-2424491|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|reactome:R-GGA-2871796|refseq:NP_990348.1|mint:MINT-6825978(identity)|uniprotkb:Q6LC82(Q6LC82)	go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0017166"(vinculin binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|rcsb pdb:2L6F|rcsb pdb:2L6G|rcsb pdb:2L6H|rcsb pdb:4R32|go:"GO:0005925"(focal adhesion)|refseq:NP_990315.1|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|mint:P49024|mint:MINT-6825986(identity)|uniprotkb:P49024(P49024)	-	comment:mint	-	figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9031	rogid:gFcb1txdr5lCKvDMcZnyDVkcSbg9031	intact-crc:F654F64728758124|rigid:Dnf8vYdzqghDzURIBMMfdtEA+T4	false	glutathione s tranferase tag:?-?(MINT-6825981)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5ZLR6	uniprotkb:Q9DG15	intact:EBI-8631977|intact:MINT-6825004	intact:EBI-8612826|intact:MINT-260012|uniprotkb:E1BYJ4	psi-mi:arhg6_chick(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:RCJMB04_5b15(orf name)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)	psi-mi:q9dg15_chick(display_long)	psi-mi:"MI:0096"(pull down)	Albertinazzi et al. (2003)	mint:MINT-6825945|pubmed:12686588|doi:10.1091/mbc.E02-07-0406	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8632028|mint:MINT-6825992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR032409|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001006432.1|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|mint:Q5ZLR6|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6825993(identity)|uniprotkb:Q5ZLR6(Q5ZLR6)	go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|interpro:IPR032352|interpro:IPR020683|interpro:IPR022018|refseq:NP_989627.1|interpro:IPR038508|interpro:IPR036770|interpro:IPR037278|mint:Q9DG15|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|mint:MINT-6825996(identity)|uniprotkb:Q9DG15(Q9DG15)	-	function:"Acts as a RAC1 guanine nucleotide exchange factor (GEF)"|comment:mint	comment:mint	figure legend:F3A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:CBL2c9qaCqyB8+OkQNYJEQ5Mktg9031	rogid:nPWbyHDAbeLHadKv/FLZLtVLShM9031	intact-crc:0D85B48C9BE9BB5C|rigid:+eAV4BZOFx4RIG74zq8m1E8qRhc	false	-	glutathione s tranferase tag:?-?(MINT-6825999)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)