#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0AFZ5 uniprotkb:P0A6H5 intact:EBI-2012039|uniprotkb:P03840|uniprotkb:P08846|uniprotkb:P71224|ensemblbacteria:AAC74044|ensemblbacteria:BAA35716 intact:EBI-369317|uniprotkb:Q2M8M7|uniprotkb:P32168|ensemblbacteria:AAC76913|ensemblbacteria:BAE77379 psi-mi:sula_ecoli(display_long)|uniprotkb:sulA(gene name)|psi-mi:sulA(display_short)|uniprotkb:sfiA(gene name synonym)|uniprotkb:b0958(locus name)|uniprotkb:JW0941(locus name) psi-mi:hslu_ecoli(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:htpI(gene name synonym)|uniprotkb:b3931(locus name)|uniprotkb:JW3902(locus name)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:Heat shock protein HslU(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2003) pubmed:12670962|imex:IM-20409 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2506597|imex:IM-20409-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000288710.1|refseq:NP_415478.1|dip:DIP-10945N|ensemblbacteria:AAC74044(transcript)|ensemblbacteria:b0958(gene)|ensemblbacteria:BAA35716(gene)|ensemblbacteria:BAA35716(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009432"(SOS response)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:2000245"(negative regulation of FtsZ-dependent cytokinesis)|interpro:IPR004596(Cell division inhibitor SulA)|interpro:IPR027417 refseq:WP_001293341.1|refseq:NP_418366.1|ensemblbacteria:AAC76913(transcript)|ensemblbacteria:b3931(gene)|ensemblbacteria:BAE77379(gene)|ensemblbacteria:BAE77379(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|rcsb pdb:1DO0|rcsb pdb:1DO2|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1YYF|rcsb pdb:5JI3|rcsb pdb:5TXV|rcsb pdb:6PXI|rcsb pdb:6PXK|rcsb pdb:6PXL|interpro:IPR004491(Heat shock protein HslU)|dip:DIP-31855N - - - figure legend:Figs. 5 and 6.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/12/04 2014/10/16 rogid:jDP2XT7XgQsile5JZQSJ+GXtHZs83333 rogid:EERS/16O3gptXoyz8uOxjqZiY4883333 intact-crc:443B0BD12D54EDBD|rigid:+E8iJzzJWEkVfbo8iSGmr+2zfcw false mutation increasing interaction:89-89|mutation disrupting interaction:57-57|sufficient binding region:43-125(IPR004596) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7B8 uniprotkb:P0A7B8 intact:EBI-552265|uniprotkb:P31059|uniprotkb:P97542|uniprotkb:Q2M8M8|ensemblbacteria:AAC76914|ensemblbacteria:BAE77378 intact:EBI-552265|uniprotkb:P31059|uniprotkb:P97542|uniprotkb:Q2M8M8|ensemblbacteria:AAC76914|ensemblbacteria:BAE77378 psi-mi:hslv_ecoli(display_long)|uniprotkb:hslV(gene name)|psi-mi:hslV(display_short)|uniprotkb:htpO(gene name synonym)|uniprotkb:b3932(locus name)|uniprotkb:yiiC(gene name synonym)|uniprotkb:Heat shock protein HslV(gene name synonym)|uniprotkb:JW3903(locus name) psi-mi:hslv_ecoli(display_long)|uniprotkb:hslV(gene name)|psi-mi:hslV(display_short)|uniprotkb:htpO(gene name synonym)|uniprotkb:b3932(locus name)|uniprotkb:yiiC(gene name synonym)|uniprotkb:Heat shock protein HslV(gene name synonym)|uniprotkb:JW3903(locus name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2003) pubmed:12670962|imex:IM-20409 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2585242|imex:IM-20409-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418367.1|refseq:WP_000208242.1|dip:DIP-35866N|ensemblbacteria:AAC76914(transcript)|ensemblbacteria:b3932(gene)|ensemblbacteria:BAE77378(gene)|ensemblbacteria:BAE77378(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR022281|interpro:IPR023333|interpro:IPR029055|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1NED|rcsb pdb:4G4E|rcsb pdb:5JI3|rcsb pdb:6PXI refseq:NP_418367.1|refseq:WP_000208242.1|dip:DIP-35866N|ensemblbacteria:AAC76914(transcript)|ensemblbacteria:b3932(gene)|ensemblbacteria:BAE77378(gene)|ensemblbacteria:BAE77378(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR022281|interpro:IPR023333|interpro:IPR029055|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1NED|rcsb pdb:4G4E|rcsb pdb:5JI3|rcsb pdb:6PXI - - - figure legend:Fig. 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/12/04 2014/10/16 rogid:8q8Ps3ek2qLLuIwtux7TR7EQ70g83333 rogid:8q8Ps3ek2qLLuIwtux7TR7EQ70g83333 intact-crc:5F59C4CBA2F5714B|rigid:MWXS7L0Wtdobs/0ttHpF/lTUwBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A7B8 uniprotkb:P0A6H5 intact:EBI-552265|uniprotkb:P31059|uniprotkb:P97542|uniprotkb:Q2M8M8|ensemblbacteria:AAC76914|ensemblbacteria:BAE77378 intact:EBI-369317|uniprotkb:Q2M8M7|uniprotkb:P32168|ensemblbacteria:AAC76913|ensemblbacteria:BAE77379 psi-mi:hslv_ecoli(display_long)|uniprotkb:hslV(gene name)|psi-mi:hslV(display_short)|uniprotkb:htpO(gene name synonym)|uniprotkb:b3932(locus name)|uniprotkb:yiiC(gene name synonym)|uniprotkb:Heat shock protein HslV(gene name synonym)|uniprotkb:JW3903(locus name) psi-mi:hslu_ecoli(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:htpI(gene name synonym)|uniprotkb:b3931(locus name)|uniprotkb:JW3902(locus name)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:Heat shock protein HslU(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2003) pubmed:12670962|imex:IM-20409 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2585246|imex:IM-20409-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418367.1|refseq:WP_000208242.1|dip:DIP-35866N|ensemblbacteria:AAC76914(transcript)|ensemblbacteria:b3932(gene)|ensemblbacteria:BAE77378(gene)|ensemblbacteria:BAE77378(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR022281|interpro:IPR023333|interpro:IPR029055|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1NED|rcsb pdb:4G4E|rcsb pdb:5JI3|rcsb pdb:6PXI refseq:WP_001293341.1|refseq:NP_418366.1|ensemblbacteria:AAC76913(transcript)|ensemblbacteria:b3931(gene)|ensemblbacteria:BAE77379(gene)|ensemblbacteria:BAE77379(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|rcsb pdb:1DO0|rcsb pdb:1DO2|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1YYF|rcsb pdb:5JI3|rcsb pdb:5TXV|rcsb pdb:6PXI|rcsb pdb:6PXK|rcsb pdb:6PXL|interpro:IPR004491(Heat shock protein HslU)|dip:DIP-31855N - - - figure legend:Fig. 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/12/04 2014/10/16 rogid:8q8Ps3ek2qLLuIwtux7TR7EQ70g83333 rogid:EERS/16O3gptXoyz8uOxjqZiY4883333 intact-crc:A33FCBD06DDF8ED8|rigid:iMdTvcIYAnZzFGe74RNa+Ax06LA false - sufficient binding region:198-443,1-109 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A6H5 uniprotkb:P0A6H5 intact:EBI-369317|uniprotkb:Q2M8M7|uniprotkb:P32168|ensemblbacteria:AAC76913|ensemblbacteria:BAE77379 intact:EBI-369317|uniprotkb:Q2M8M7|uniprotkb:P32168|ensemblbacteria:AAC76913|ensemblbacteria:BAE77379 psi-mi:hslu_ecoli(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:htpI(gene name synonym)|uniprotkb:b3931(locus name)|uniprotkb:JW3902(locus name)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:Heat shock protein HslU(gene name synonym) psi-mi:hslu_ecoli(display_long)|uniprotkb:hslU(gene name)|psi-mi:hslU(display_short)|uniprotkb:htpI(gene name synonym)|uniprotkb:b3931(locus name)|uniprotkb:JW3902(locus name)|uniprotkb:Unfoldase HslU(gene name synonym)|uniprotkb:Heat shock protein HslU(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2003) pubmed:12670962|imex:IM-20409 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2585258|imex:IM-20409-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_001293341.1|refseq:NP_418366.1|ensemblbacteria:AAC76913(transcript)|ensemblbacteria:b3931(gene)|ensemblbacteria:BAE77379(gene)|ensemblbacteria:BAE77379(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|rcsb pdb:1DO0|rcsb pdb:1DO2|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1YYF|rcsb pdb:5JI3|rcsb pdb:5TXV|rcsb pdb:6PXI|rcsb pdb:6PXK|rcsb pdb:6PXL|interpro:IPR004491(Heat shock protein HslU)|dip:DIP-31855N refseq:WP_001293341.1|refseq:NP_418366.1|ensemblbacteria:AAC76913(transcript)|ensemblbacteria:b3931(gene)|ensemblbacteria:BAE77379(gene)|ensemblbacteria:BAE77379(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|rcsb pdb:1DO0|rcsb pdb:1DO2|rcsb pdb:1E94|rcsb pdb:1G4A|rcsb pdb:1G4B|rcsb pdb:1HQY|rcsb pdb:1HT1|rcsb pdb:1HT2|rcsb pdb:1YYF|rcsb pdb:5JI3|rcsb pdb:5TXV|rcsb pdb:6PXI|rcsb pdb:6PXK|rcsb pdb:6PXL|interpro:IPR004491(Heat shock protein HslU)|dip:DIP-31855N - - - figure legend:Fig. 4.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/12/04 2014/10/16 rogid:EERS/16O3gptXoyz8uOxjqZiY4883333 rogid:EERS/16O3gptXoyz8uOxjqZiY4883333 intact-crc:EC40D22DDAD33D1F|rigid:1PqDf3/ktjPxBdx0/3iim3DsHEg false sufficient binding region:110-241 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)