#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38987 uniprotkb:P38285 intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131882|imex:IM-19189-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 - crc64:F650C8946A03707C crc64:EA1EC675D6A84F20 figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/05 2014/10/16 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 intact-crc:515B88199557A230|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38285 uniprotkb:P38987 intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131893|imex:IM-19189-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 - crc64:EA1EC675D6A84F20 crc64:F650C8946A03707C figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/05 2014/10/16 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 intact-crc:DD0AC62F75B10216|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P27636 uniprotkb:P38987 intact:EBI-4200|uniprotkb:D6VPM6|ensemblfungi:YAR019C intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C psi-mi:cdc15_yeast(display_long)|uniprotkb:CDC15(gene name)|psi-mi:CDC15(display_short)|uniprotkb:LYT1(gene name synonym)|uniprotkb:YAR019C(locus name) psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131901|imex:IM-19189-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009411.2|sgd:S000000072|dip:DIP-5728N|mint:P27636|ensemblfungi:YAR019C(gene)|ensemblfungi:YAR019C_mRNA(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903024"(positive regulation of ascospore-type prospore membrane formation)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2871796 refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 - crc64:99383BD871A4A726 crc64:F650C8946A03707C figure legend:Fig 5B, 5C|stimulant:Interaction is enhanced by deletion of AMN1 or BFA1.|inhibition:Interaction is inhibited by over-expression of AMN1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/01/05 2014/10/16 rogid:yqpqAQ/5PSh5Ei2oS8nlSQzojqs559292 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 intact-crc:62F1963B0D655BA2|rigid:VVs6spIjwTrUKAI2+/wrIvBdDWY false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38987 uniprotkb:P38285 intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131920|imex:IM-19189-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 - crc64:F650C8946A03707C crc64:EA1EC675D6A84F20 figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2009/01/05 2014/10/16 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 intact-crc:F46934B37D2B8080|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38987 uniprotkb:P38285 intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131934|imex:IM-19189-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 - crc64:F650C8946A03707C crc64:EA1EC675D6A84F20 figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/05 2014/10/16 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 intact-crc:17CE8EDC4887F0BB|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false glutathione s tranferase tag:n-n his tag:n-n|35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38285 uniprotkb:P38987 intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131942|imex:IM-19189-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 - crc64:EA1EC675D6A84F20 crc64:F650C8946A03707C figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/05 2014/10/16 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 intact-crc:C8A097F28D024EDC|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false glutathione s tranferase tag:n-n 35s radiolabel:?-?|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38285 uniprotkb:P38987 intact:EBI-20853|uniprotkb:D6VQF3|ensemblfungi:YBR158W intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C psi-mi:amn1_yeast(display_long)|uniprotkb:CST13(gene name synonym)|uniprotkb:YBR158W(locus name)|uniprotkb:YBR1208(orf name)|uniprotkb:AMN1(gene name)|psi-mi:AMN1(display_short)|uniprotkb:ICS4(gene name synonym)|uniprotkb:Chromosome stability protein 13(gene name synonym)|uniprotkb:Increased copper-sensitivity protein 4(gene name synonym) psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:"MI:0096"(pull down) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2132027|imex:IM-19189-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009716.1|sgd:S000000362|dip:DIP-4930N|ensemblfungi:YBR158W(gene)|ensemblfungi:YBR158W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0043624"|go:"GO:0051301"(cell division)|go:"GO:2001042"(negative regulation of septum digestion after cytokinesis)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675 refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 - crc64:EA1EC675D6A84F20 crc64:F650C8946A03707C figure legend:Fig 6E, 6H|inhibition:Interaction is inhibited by His6-CDC15.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/05 2014/10/16 rogid:eeto5jdaq7nMtlvX3UGYw4YAh9c559292 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 intact-crc:92D4EBCCA20E2E8D|rigid:9uWehVlxOKAA0xIpyI0qvEnmlUI false glutathione s tranferase tag:n-n his tag:n-n|35s radiolabel:?-?|mutation decreasing interaction:34-34|mutation disrupting interaction:135-135 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27636 uniprotkb:P38987 intact:EBI-4200|uniprotkb:D6VPM6|ensemblfungi:YAR019C intact:EBI-19113|uniprotkb:D6VZA9|ensemblfungi:YML064C psi-mi:cdc15_yeast(display_long)|uniprotkb:CDC15(gene name)|psi-mi:CDC15(display_short)|uniprotkb:LYT1(gene name synonym)|uniprotkb:YAR019C(locus name) psi-mi:tem1_yeast(display_long)|uniprotkb:YML064C(locus name)|uniprotkb:TEM1(gene name)|psi-mi:TEM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wang et al. (2003) pubmed:12628189|imex:IM-19189 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2131993|imex:IM-19189-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009411.2|sgd:S000000072|dip:DIP-5728N|mint:P27636|ensemblfungi:YAR019C(gene)|ensemblfungi:YAR019C_mRNA(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903024"(positive regulation of ascospore-type prospore membrane formation)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2871796 refseq:NP_013647.1|sgd:S000004529|ensemblfungi:YML064C(gene)|ensemblfungi:YML064C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005816"(spindle pole body)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0023056"(positive regulation of signaling)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017231(Small GTPase, Tem1)|interpro:IPR027417|dip:DIP-1691N|mint:P38987 - crc64:99383BD871A4A726 crc64:F650C8946A03707C figure legend:Fig 6D, 6G|inhibition:Interaction is inhibited by GST-AMN1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/01/05 2014/10/16 rogid:yqpqAQ/5PSh5Ei2oS8nlSQzojqs559292 rogid:7qYoNacq3xo5Qd9zT5xM1WZwVgc559292 intact-crc:C5E941A92301E477|rigid:VVs6spIjwTrUKAI2+/wrIvBdDWY false myc tag:n-n his tag:n-n|35s radiolabel:?-?|mutation disrupting interaction:135-135|mutation disrupting interaction:34-34 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)