#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P45976 uniprotkb:Q06102 intact:EBI-6940|uniprotkb:D6VWR1|ensemblfungi:YJR093C intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C psi-mi:fip1_yeast(display_long)|uniprotkb:J1911(orf name)|uniprotkb:YJR093C(locus name)|uniprotkb:FIP1(gene name)|psi-mi:FIP1(display_short) psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name) psi-mi:"MI:0096"(pull down) Tacahashi et al. (2003) pubmed:12626716|imex:IM-20251 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2215864|imex:IM-20251-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012626.1|sgd:S000003853|mint:P45976|dip:DIP-2029N|ensemblfungi:YJR093C(gene)|ensemblfungi:YJR093C_mRNA(transcript)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|rcsb pdb:3C66|reactome:R-SCE-77595 refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595 - crc64:471CA2B0CDF99D0A crc64:79C5993AE4E670EA figure legend:Figure 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2009/02/06 2014/10/16 rogid:iccGQAauzvRX7q/SWk7cBHcHUa0559292 rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292 intact-crc:3B6DA67554F4145E|rigid:yvr4PN/2YCuaCaoif/ectcmA80w false his tag:?-? necessary binding region:119-146(IPR000571) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06102 uniprotkb:P45976 intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C intact:EBI-6940|uniprotkb:D6VWR1|ensemblfungi:YJR093C psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name) psi-mi:fip1_yeast(display_long)|uniprotkb:J1911(orf name)|uniprotkb:YJR093C(locus name)|uniprotkb:FIP1(gene name)|psi-mi:FIP1(display_short) psi-mi:"MI:0096"(pull down) Tacahashi et al. (2003) pubmed:12626716|imex:IM-20251 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2215894|imex:IM-20251-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595 refseq:NP_012626.1|sgd:S000003853|mint:P45976|dip:DIP-2029N|ensemblfungi:YJR093C(gene)|ensemblfungi:YJR093C_mRNA(transcript)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|rcsb pdb:3C66|reactome:R-SCE-77595 - crc64:79C5993AE4E670EA crc64:471CA2B0CDF99D0A figure legend:Figure 5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/06 2014/10/16 rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292 rogid:iccGQAauzvRX7q/SWk7cBHcHUa0559292 intact-crc:309972FD260A0C93|rigid:yvr4PN/2YCuaCaoif/ectcmA80w false mutation decreasing interaction:130-130|35s radiolabel:?-? his tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q06102 uniprotkb:Q06224 intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C intact:EBI-38345|uniprotkb:D6VYS4|ensemblfungi:YLR277C psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name) psi-mi:ysh1_yeast(display_long)|uniprotkb:YSH1(gene name)|psi-mi:YSH1(display_short)|uniprotkb:BRR5(gene name synonym)|uniprotkb:Yeast 73 kDa homolog 1(gene name synonym)|uniprotkb:YLR277C(locus name)|uniprotkb:mRNA 3'-end-processing protein YSH1(gene name synonym) psi-mi:"MI:0096"(pull down) Tacahashi et al. (2003) pubmed:12626716|imex:IM-20251 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2215871|imex:IM-20251-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595 refseq:NP_013379.1|sgd:S000004267|mint:Q06224|dip:DIP-2470N|ensemblfungi:YLR277C(gene)|ensemblfungi:YLR277C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|rcsb pdb:6I1D|reactome:R-SCE-77595 - crc64:79C5993AE4E670EA crc64:901582F0C33AD6F7 figure legend:Figure 6|comment:"The wild-type and all of the truncations tested were able to pull down His6-Brr5-HA3, but GST-yth1(57-208)N2 and GST-yth1(1-118/147-208)ZF4 exhibited a weaker interaction. Thus, ZF4 and the N-terminus including ZF1 both contribute to efficient binding of Brr5."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2009/02/06 2014/10/16 rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292 rogid:hzM2FredjCDlhdDUSIwMuLop/DU559292 intact-crc:BC5397B520888A20|rigid:J2vaBJ0opJUKG4B6pnFOQXzkzA8 false glutathione s tranferase tag:?-? ha tag:?-?|his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)